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p14ARF in Medical News

Also in the May 27 JNCI

... Overlapping Tumor Suppressor Genes Independently Involved in Melanoma Mutations in the p14arf tumor suppressor gene (ARF) may play a role in melanoma, independent of the effect of the p16 gene. ARF and p16 are overlapping genes at a location...
p14ARF in other areas

p14arf - Wikipedia, the free encyclopedia

p14ARF is an alternate reading frame (ARF) product of the CDKN2A locus. Both p16INK4a and p14ARF are involved in cell cycle regulation. p14ARF inhibits mdm2, thus promoting p53, which promotes p21 activation, which then binds and inactivates certain cyclin-CDK complexes, which would otherwise promote transcription of genes that would carry the cell through...

p14ARF antibody, p14ARF [ARF 4C6/4] Antibody, Mouse Monoclonal Antibody

... mouse p14ARF antibody (interacts with human - not yet tested in other species) ... The p14ARF (or P19ARF in mouse) proteins can induce both G1 and G2 phase arrest ...

p14ARF, p15INK4b and p16INK4a methylation status in chronic myelogenous ...

The INK4 family of proteins p15INK4b, p14ARF and p16INK4a function as cell cycle ... p14ARF and p16INK4a promoter methylation often occurs in solid tumors but also ...

Sidney Kimmel Cancer Center - Gjerset Lab

p14ARF engages in interactions and functions beyond the p53 pathway that can be ... Epigenetic changes at the p14ARF locus may be among the earliest occurrences in ...

Antibody Directory | Advanced Search

Search Antibodies | monoclonal, polyclonal, primary, secondary and therapeutic ... Your Search for "p14ARF " returned 3 Antibodies. Filter by Company Name ...

p14ARF Promoter Hypermethylation in Plasma DNA as an Indicator of ...

Plasma p14ARF promoter hypermethylation was associated with the presence of ... Frequent p16-Independent Inactivation of p14ARF in Human Melanoma ...
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