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Osteoarthritis at Biology News

Matrilin-3 gene discovered to prevent onset of osteoarthritis

A gene that is associated with osteoarthritis and skeletal deformities in people has been shown to be responsible for preventing the onset of osteoarthritis in adult mice, according to a recent study led by Rhode Island Hospital. The matrilin-3 gene plays a role in early bone development, controls bone mineral density in adulthood and prevents osteoarthritis later in life. Mutations in m...

Osteoarthritis may be sign of faster 'biological ageing'

Osteoarthritis, the degenerative inflammatory bone disease, may be a sign of faster "biological ageing," suggests research published ahead of print in the Annals of the Rheumatic Diseases. X-rays of both hands were taken of all participants to check for signs...
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New device for discerning Osteoarthritis

According to researchers, a new technique which images cartilage could lead to earlier detection of Osteoarthritis. An X ray exam is the standard way of detecting Osteoarthritis, a painful disease //where the cartilage between the joints wears away. But an X ray cannot image the cartilage direct it only shows that the gap between the bones is getting narrower. Researchers at the Unive...

Meniscal Damage Could Lead To Cartilage Loss And Knee Osteoarthritis

A new study has now provided insights into association between cartilage loss, meniscal damage and knee osteoarthritis. Osteoarthritis is a severe disabling disease// that affects nearly 20 million Americans, characterized by loss of cartilage. A pair of meniscus, situated on either side of the knee offer support and protection to keep it healthy. The C-shaped tissue performs many fu...

Osteoarthritis and Estrogen are connected

According to researchers from the University of California, they have observed that postmenopausal women who use estrogen are at a higher risk for developing Osteoarthritis. Osteoarthritis is a tissue change in the joints that causes pain in that area.// Osteoarthritis affects 20 percent to 30 percent of adults over 40 years old. Experts estimate up to 70 percent of women 60 years or older suffer...

Hyaluronan supplementation therapy for Knee Osteoarthritis

Osteoarthritis, a common problem in the knees, is a form of arthritis where one or more joints undergo tissue change. A key problem involved in in these type of joint problems is the loss of a special salt called hyaluronan within the fluid that moisturizes the area. This fluid is called synovial fluid. Hyaluronan supplementation injections are being given to humans since 1987, after the therapy...

Green tea beneficial in preventing osteoarthritis

Green tea, first discovered in China nearly 5000 years ago, has been linked to many health benefits including preventing coronary heart disease, stroke and certain types of cancer. Researchers in the University of Sheffield have now discovered that two compounds found in green tea, EGCG (epigallocatchin gallate) and ECG (epicatechin gallate) can help prevent osteoarthritis by blocking the enzyme...

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Anesiva Announces Phase 2 Data Showing Substantial, Long-Term Pain Reductions with Adlea(TM) (formerly 4975) in Osteoarthritis of the Knee

- Pain Reductions Observed at Eight Weeks Sustained up to 12 Weeksand Drug Remains Very Well Tolerated - SOUTH SAN FRANCISCO, Calif., July 02, 2007/PRNewswire-FirstCall/ -- Anesiva, Inc. today announced preliminarylonger-term, follow-up results from a Phase 2 study showing that a1mg treatment with Adlea(TM) (formerly 4975) in patients withmoderate-to-severe osteoarthritis of the knee prod...

Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension

* New data from 741-patient trial show those treated withPrexige experienced significantly smaller impact on blood pressurecompared to ibuprofen[1] * Many patients with osteoarthritis also have high bloodpressure; even small changes in blood pressure can impactcardiovascular risk[2],[3] * Prexige approved in more than 50 countries and currently underreview in US for use in o...

Lumiracoxib Study Showed Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension

New data From 741-patient Trial Show Those Treated with LumiracoxibExperienced Significantly Smaller Impact on Blood Pressure Comparedto Ibuprofen EAST HANOVER, N.J., June 15, 2007 /PRNewswire/ -- Patients withosteoarthritis who also have controlled hypertension experienced aslight decrease in average daily blood pressure when treated withthe investigational selective COX-2 inhibitor lumi...
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