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orthologous in Medical News

Researchers Identify Sipa 1 Gene, Responsible For Cancer Metastasis

...ntitative trait genetic mapping showed the presence of a putative metastasis efficiency locus on mouse chromosome 19. This chromosome region, which is orthologous to human 11q12-13, harbors a known metastasis suppressor gene Brms1. However, this gene has no obvious polymorphisms that influence metastasis. ...

Evoprinter, a multigenomic comparative tool for rapid identification of functionally important DNA

...a long-standing goal of biology. The comparison of orthologous DNA sequences from multiple vertebrate or inverteb... step in this process is the alignment of multiple orthologous DNAs. The multiDNA alignments are accomplished eit...c sequence is required to initiate the analysis of orthologous DNAs from multiple species. Based on the success o...
orthologous in Biological News

Computational verification of protein-protein interactions by orthologous co-expression

In the March 3 issue of Nature, Johns Hopkins researchers report that two proteins best known for very different activities actually come together to turn the liver into a sugar-producing factory when food is scarce. Because the liver's production of sugar is a damaging problem in people with diabe...

Genomatix gets patent for comparative genomics method

..., announced today that it was issued patent No. EP 1 800 232 B1, "Identification and assignment of functionally corresponding regulatory sequences for orthologous loci in eukaryotic genomes" by the European Patent Office. The Patent relates to a sophisticated method for identification of networks of functiona...

Corn researchers discover novel gene shut-off mechanisms

...lass of small RNAs produced by RDR2. Independently of the UD groups, Chandler and her team at the University of Arizona had identified from corn an orthologous gene--a gene that has the same function in different organisms. In corn, this gene, which the Chandler lab found, is called the mediator of paramutati...
orthologous in Biological Definition

Evolution

...ces where other evidence is scarce. Further evidence for common descent comes from genetic detritus such as pseudogenes , regions of DNA which are orthologous to a gene in a related organism, but are no longer active and appear to be undergoing a steady process of degeneration [6] . Since metabolic proc...

Gene duplication

...gene duplication event are paralogs. Paralogs usually code for proteins with different function and/or structure as stated above. This is opposed to orthologous genes that code for proteins with similar function but that exists in different species. Orthologs are created from a speciation event. (See Homolo...
orthologous in Biological Dictionary

Pseudoautosomal regions

... 1225 ... the GC counts along the human pseudoautosomal region 1. ... The great ape short-arm pseudoautosomal region (PAR1) is ... by the orthologous pseudoautosomal regions of many other. mammals. ... It has been demonstrated that recombination in the human p-arm pseudoautosomal regio...

Post-meiotic segregation

...ic abnormalities. MutS homologs. Msh2. No ... have an increase in post - meiotic segregation (PMS), a term ... post - meiotic segregation , orthologous to yeast PMS1) and. PMS1 (orthologous to yeast MLH2) ... ...

Intergenic

...ergenic regions, often occur in clumps and are rare ... In order to find orthologous intergenic regions, we searched for pairs of ... The 16S-23S rDNA int...rgenic regions of plant nuclear genomes, because plant ... In theory orthologous intergenic data is valuable for studying ... Details on Gene Mutation,...

Exon

...rmation about Exon in the Columbia Encyclopedia, Computer Desktop Encyclopedia, computing dictionary. ... the two motifs are conserved in mouse orthologous genes that undergo exon skipping. ... For example, mutations in exon 18 of the breast cancer BRCA1 gene cause ... PTB: A REPRESSOR OF EXON...

Contig map

...es in the Contig Map ... As a result, extensive BAC contig maps should be readily assembled, even in ... The complete contig map for the orthologous region of the dog genome is shown in ... A chromosome map showing the locations of those regions of a chromosome where ... Contig maps ...

Binding site

...n AMPK 82 - 535 ... Transcription factor binding site predictions for each of 2086 E. coli genes are ... sorted by known TF- binding sites . orthologous gene lists links ... Biological activity and binding site characteristics of the PA1b entomotoxin on ... This binding site was present on...
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