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Oocytes in Medical News

Renewable Oocytes of Mice created hope in Human Fertility Treatment

Using mice as an experimental animal, researchers have discovered that despite its age female mice have a renewable number of oocytes (egg) supply in their ovaries//. As a preliminary step, this study would pave way for many further discoveries in the field of ovarian stem cell research and wom...

Reduced ovarian reserve associated with increased risk of trisomic pregnancy

...herapy, may cause a decrease in ovarian reserve. However, a woman's ovarian reserve is most likely to be mainly determined by her genes: the number of oocytes a woman is born with and the rate of depletion of her oocyte pool is believed to be heritable. This is reflected in the similar ages at menopause of m...

Stem Cells Spur New Eggs in Ovaries of Adult Mice

...ale mammals, including humans, are born with a finite number of the eggs or oocytes needed to produce offspring. "These stem cells are continuous. They were...said. For years, scientists had believed that the capability to produce oocytes was lost in most mammalian species at birth. That line of thought was t...

Fertility experts present the latest research at reproductive medicine meeting

...ted with any measurable detrimental effects on the oocytes or resulting embryos. They found that Ovidrel inje...tion induction and as a result, had similar mature oocytes harvested as age-matched controls. The fertilizati... and all patients successfully achieved embryos or oocytes for cryopreservation despite their illness and the...

Technique Preserves Future Fertility in Girls With Cancer

...researchers at Hadassah Hebrew University Medical Center in Jerusalem, working with 19 patients ages 5 to 20, were able to retrieve an average of nine oocytes (immature eggs) per patient, and 34 percent of these eggs successfully matured. The researchers will next test the ability of these eggs to become fer...

New ovarian stimulation technique offers more cancer patients the chance to preserve their fertility

...1.4 days in the second group. A mean average of 13 oocytes were collected from the first group and 10 from the second group. Nearly 77% and 73% of the oocytes were mature in the respective groups, and after in...plasmic sperm injection (ICSI), 70% and 75% of the oocytes were fertilised respectively. The researchers f...

June 2008 highlights

...found that reproductive markers were disrupted not only in the female offspring of these rats, but also in the grand offspring, which are derived from oocytes present in fetuses of the treated females. Changes in the second generation included blunting of preovulatory LH release, reduced progesterone concent...

Pacific Fertility Center Announces Breakthrough in Egg Freezing Technology

...th embryos created from vitrified and warmed donor oocytes (eggs), successfully delivered a baby in late Octo...ology to oocytes. "Even though we've been handling oocytes and embryos for many years, this technology provid...ith the procedure, we began to freeze high quality oocytes from donors that had proven fertility. Using these...

Study Spots Gene That Plays Role in Infertility

... where they are available for immediate release and, perhaps, fertilization. Menopause occurs when there are no more follicles and, therefore, no more oocytes left. The length of a woman's reproductive life is determined by the size of her follicle pool and the rate at which this pool is depleted. Unti...

Human embryonic stem cell lines created that avoid immune rejection

...Stem Cell and colleagues at the company and from the Russian Academy of Medical Sciences, described the successful parthenogenetic activation of human oocytes and the subsequent derivation of cell lines having the morphology and markers characteristic of human embryonic stem cells. In a paper entitled, HLA H...
Oocytes in Medical Technology

CRi Oosight(TM) Instrument Crucial in IVF Breakthrough Demonstrating a Correlation Between Non-Invasive Egg Metrics and Pregnancy

... and zona. In this study, spindle density was significantly higher in those oocytes resulting in pregnancy. The work by Dr. Kilani's group, "Are there non-invasive markers in human oocytes that can predict pregnancy outcome?" was published in March by Reproductive...

Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs

...CESTER, Mass., Feb. 2 /PRNewswire-FirstCall/ -- Advanced Cell Technology, Inc. (OTC Pink Sheets: ACTC) and its collaborators reported today that human oocytes (or 'eggs') have the capacity to extensively reprogram adult human cells. The research, which appears online ahead of print in the journal Cloning an...

Schering-Plough Announces Phase III Data for Sustained Follicle Stimulant

...ed cycle) was similar to that achieved in patients receiving 200 IU recombinant FSH (follitropin beta) (38.1 percent per started cycle). The number of oocytes retrieved (co-primary endpoint) was within the limits of clinical equivalence, and the estimated difference of +1.2 was in favor of the corifollitropi...

Embryo Viability Studies Support Utility of Novel, Metabolomic Profiling Technology

...esented this week at the 24th annual Meeting of the European Society for Human Reproduction and Embryology (ESHRE), include perspectives in evaluating oocytes (eggs), embryos and blastocysts (late stage embryos) to determine embryo viability using the company's novel, proprietary technology. "As embryos de...

Molecular Biometrics Hires Denny Sakkas, PhD Renowned Yale Embryologist and International Thought-Leader, as Chief Scientific Officer; Opening U.S. Research Facility

...ny's lead product candidates are diagnostic tests used to evaluate embryos, oocytes and sperm viability for in vitro fertilization (IVF). Molecular Biometric...s in the areas of infertility (to determine viability of embryos, sperm and oocytes used in IVF), maternal fetal medicine (to monitor the health status of a gr...

Study Reports Successful Cloning of Human Embryo Using Adult DNA

...ument, the cloning of a human embryo using donated oocytes (egg cells) and DNA from the cells of an adult don...sies. Subsequently, several of the reconstructed oocytes continued to develop as normal embryos, to the bla...sful results, including the use of freshly donated oocytes from successful egg donors. While the study is a...

Ferring Reports on ENDOMETRIN Presentations at Pacific Coast Reproductive Society Annual Meeting

... <0.001 BMI 25.0 24.9 0.181 Duration 10.0 10.6 oocytes 14.0 13.4 0.225 Continuing Pregnancy (%) 41.3 40.6 0...
Oocytes in Medical Products

IX51 Inverted System Microscope

Features:...logen illumination pillar and has a 45mm working distance and 0.5NA to provide excellent 3-D relief images of specimens in plastic vessels, especially oocytes during microinjection observations ...
Company:Olympus America Scientific
Oocytes in Medical Dictionary

Immunofluorescence

...For immunofluorescence staining, sections were quenched for 15 min in Tris ... Immunofluorescence microscopy on sections of paraformaldehyde-fixed oocytes was ... Translations of immunofluorescence . immunofluorescence synonyms, immunofluorescence antonyms. ... indirect immunofluorescence . tec...
Oocytes in Biological News

Stem cell research: From molecular physiology to therapeutic applications

...e reliably used to fulfill the promise of stem cell therapy in regenerative medicine. Dr. Lin Liu's group found that pES cells generated from immature oocytes in mice exhibit pluripotency resembling fES cells, as evidenced by similarly high chimera production and germline transmission. Thus, immature eggs ma...

Ovarian transplantation: First baby is born after a new technique

...r of eggs we could, and carry out an IVF procedure on this patient. "Six months after the operation, we transferred two blastocysts. A total of 22 oocytes were retrieved and produced 16 embryos, which in turn produced seven blastocysts. Unfortunately the first time round this patient developed an ectopic...

Ovarian transplantation: New technique gives greatly improved results in this delicate operation

...esting with fluorescent microscopy to determine the loss or preservation of oocytes in fresh and frozen ovarian tissue of 15 young women undergoing cancer trea...r by classical slow freezing methods. "We found that 91.9% of the fresh oocytes were viable compared with 88.9% of those vitrified. However, slow freezing ...

Who goes abroad for fertility treatment and why?

...ium, looked in more detail at the situation in his own country. 16 out of the 18 Belgian reproductive medicine centres which were licensed to handle oocytes and create embryos were surveyed on the nationality of foreign patients coming for treatment between 2000 and 2007, as well as on the type of treatmen...

ESHRE launches international study of polar body screening

...he data at ESHRE 2010 in Rome and to start the RCT with the involvement of at least six centres in different European countries later the same year. oocytes to be used in the pilot phase will be obtained from volunteer patients who have given consent for their use in this study. There will be no age restri...

Universitat Autonoma de Barcelona researchers first to clone mice in Spain

... order to clone the animals, researchers collected oocytes and surrounding cumulus cells from several female ...e. The chromosomes were extracted from each of the oocytes and substituted with a cell from the cumulus by cytoplasm injection. Once the oocytes had been reconstructed, they were activated by sim...

Animal eggs not suitable substitutes to produce stem cells

...y Mary Ann Liebert, Inc., demonstrates that animal oocytes lack the capacity to fully reprogram adult human c...), compared the reprogramming of human cells using oocytes obtained from cows, rabbits, and humans. They repo...s." The ability to reprogram human cells using oocytes would enable the production of patient-specific st...

CSHL scientists discover a new way in which epigenetic information is inherited

...o remains to be seen whether this mechanism of epigenetic inheritance is found in organisms besides fruit flies. "Small RNAs are probably deposited in oocytes of every animal," he hypothesizes. ...

December 2008 highlights from Biology of Reproduction

... ovarian development establishes the population of oocytes and follicles and instigates evelopment of a cohor...les fail to form, the result is oocyte demise, yet oocytes are also essential for follicular development. Sev...icles appear to form in Sohlh2 -null ovaries, the oocytes are rapidly lost and follicles do not develop to t...

October 2008 Biology of Reproduction highlights

... Perils of culture. There is growing interest in the developmental origins of adult disease, and effects of both nutrition and environment on oocytes and embryos on adult health of offspring have been demonstrated. However, mechanisms by which deleterious effects are established during these early d...
Oocytes in Biological Technology

Unisense FertiliTech A/S Receives CE Mark of Approval for EmbryoScope(TM) Embryo Monitoring System

...pe, with the goal of improving embryo assessment and to facilitate the goal of elective single embryo transfer." During IVF treatment, multiple oocytes are removed from the patient and fertilized in-vitro. The resulting fertilized eggs are cultured for a period of 2 to 5 days, before the embryologist ...

Schering-Plough Announces Phase II and III Data for Corifollitropin Alfa

...orifollitropin alfa resulted in significantly more oocytes and an equally short duration of treatment as thos...eeks or more after embryo transfer. The number of oocytes retrieved was the co-primary endpoint. The incide...1% 50.6% The mean number of oocytes retrieved per attempt was 13.7 (+/-8.2) for the co...

Animal Eggs Not Suitable Substitutes to Produce Stem Cells

... Mary Ann Liebert, Inc., demonstrates that animal oocytes lack the capacity to fully reprogram adult human c... , compared the reprogramming of human cells using oocytes obtained from cows, rabbits, and humans. They repo...." The ability to reprogram human cells using oocytes would enable the production of patient-specific st...

EMD Serono Launches Landmark Patient Registry for Egg Freezing

...er a three year period. Women participating in the Registry will have their oocytes frozen, thawed and the resulting fertilized embryos transferred. It is open...alified investigators across the country who are freezing and later thawing oocytes for embryo production. Local ethics committee or Institutional Review Board...

Stemagen First to Create Cloned Human Embryos From Adult Cells

...sts were successfully created from approximately 10% of all mature donated oocytes, an unexpectedly high rate given past research in this field. The oocytes used in this study were donated, without compensation, by egg donors and intended parents undergoing egg donation cycles for reproductive purposes at ...

Your Data: Detection of Oocyte-specific Gene Expression Using Ambion's Cells-to-cDNA Kit

...ed protocol, Dr. Bortvin was able to easily detect both his gene-specific transcript and the GAPDH housekeeping mRNA from single oocytes using the Cells-to-cDNA Kit protocol. Figure 1. Gene-specific RT-PCR on a Single Mouse Oocyte Using t...

Transgenic Animals

...ts or other small mammals are used to introduce foreign DNA into oocytes or embryos (blastocysts). ... it is closer to the oocyte surface. These oocytes are subsequently transferred into the uterus of pseudopregnant ...

Intracytoplasmic Spermatocyte Injection (ICSI)

...pressing the joystick button. If several oocytes are obtained, only 34 oocytes are injected as a rule. They are then p...ams F-10-medium [5] and the remaining oocytes are then injected. Further methods of procedure ...
Oocytes in Biological Definition

Cell growth

...l adhesion between myocytes and some are involved in adhesion-dependent cell-to-cell signaling that allows for a cascade of cell fusion events. oocytes can be unusually large cells in species for which embryonic development takes place away from the mother's body. Their large size can be achieved eit...

Ploidy

...s can vary within an organism. In humans, most cells are diploid (containing one set of chromosomes from each parent), though sex cells ( sperm and oocytes ) are haploid. In contrast, tetraploidy (four sets of chromosomes), a type of polyploidy , is not uncommon in healthy plant species. Euploidy , o...

Ploidy

...s can vary within an organism. In humans, most cells are diploid (containing one set of chromosomes from each parent), though sex cells ( sperm and oocytes ) are haploid. In contrast, tetraploidy (four sets of chromosomes), a type of polyploidy , is not uncommon in healthy plant species. Euploidy , o...

Meiosis

...(visual evidence of crossing over) can be seen. In the human ovary , oocytes are stored in the diplotene stage since fetal life. Only just prior to ovul... the time of ovulation (meiosis II ends only just after fertilization ). oocytes that are not ovulated do not complete meiosis I. The end of Prophase I (a...
Oocytes in Biological Dictionary

Oocytes

An oocyte is part of the ovary development. ... Oocytes are rich in cytoplasm which contains yolk granules to nourish the cell ... oocyte ( ) n. A cell from which an egg or ovum develops by meiosis; a female gametocyte. ... Oocytes are rich in cytoplasm which contains ...

Zygotene

...requency of ENs associated with SCs and AEs during zygotene for six plant species ... At the zygotene , pachytene and diplotene stages, oocytes with fragmented axial ... The durations of the leptotene, zygotene and pachytene stages in mice were ... The staining became brighter through ...

Zona pellucida

.... Sperm– zona pellucida binding and penetration were assessed on the oocytes that ... In conclusion, defective sperm– zona pellucida interaction was...tes, ... Human zona pellucida were mechanically isolated by disrupting oocytes or embryos ... Whether the zona pellucida originates from the oocyt...

Xenopus

...iol. 42(4):476-507. de Sá, R. O. ... Microinjection of Xenopus laevis oocytes followed by thin-sectioning electron ... Part 3: Dissection of Xenopus oocytes. The next day, wash the oocytes 3 times ... Compare Cheap Prices for Xenopus at NexTag.com. Find Grea...

Spermatids

...be resolved when plastic sections are viewed ... ... Injection: Couples who go through spermatid injection should be counseled for potential ... oocytes by injecting spermatozoa, spermatids and spermatocytes. ... ... genes encode proteins located in human late spermatids and in sperm tail...

Spermatid

...body containing membrane ... A round spermatid was drawn into the injection pipette (Figure 2 b-1) ... Pronucleus formation in cynomolgus monkey oocytes post-round spermatid injection (ROSI) ... Since fertilization by round spermatid nucleus was first reported (Ogura and ... Round spermati...

SnRNA

... U snRNA assemble into the export complex. ... Arrows indicate the nucleotide changes in Xenopus U2 snRNA . ... Lanes 2 and 5 are U2-depleted oocytes supplemented with synthetic U2 snRNA . ... Cell death and differentiation is a monthly research journal focused on the ... The observations tha...

Microfilament

...tion, underwent GV ... Microtubule and microfilament dynamics in porcine oocytes during meiotic maturation. ... ... examines the effects of actin mic...tion Factors ... microfilament -mediated process. ... does not occur in oocytes pretreated with microfilament ... membrane and directing microfilament o...

Lampbrush

... A Lampbrush chromosome is a large chromosome found especially in the oocytes (immature eggs) of most animals, except mammals. Lampbrush chromosomes occur during the diplotene stage of meiosis I. Lampbrush chromosomes a...

Karyoplasm

...ilin 2 is also enriched in the karyoplasm of a wide range of cell types, ... Buffer-extractable fractions from the karyoplasm of stage IV–VI oocytes contain ... "ooplasms," and thus the parallel analysis of both karyoplasm and cytoplasm (cf. ... This article is an orphan, as few or no other...
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