once

Purdue proves concept of using nano-materials for drug discovery

Researchers at Purdue University have built and demonstrated a prototype for a new class of miniature devices to study synthetic cell membranes in an effort to speed the discovery of new drugs for a variety of diseases, including cancer. The researchers created a chip about one centimeter square that holds thousands of tiny vessels sitting on top of a material that contains numerous pores...

Researchers make surprise discovery that some neurons can transmit three signals at once

Generations of neuroscientists have been indoctrinated into believing that our senses, thoughts, feelings and movements are orchestrated by a communication network of brain cells, or neurons, each responsible for relaying one specific chemical message called a neurotransmitter. Either neurons release a neurotransmitter that excites a neighboring cell, thereby triggering an electrical discharge an...

Once given 'no respect,' cells' tiny RNAS take driver's seat

Ribonucleic acid, or RNA, has long been thought to be important only to translate a gene's DNA into the proteins that are cells' workhorses. But new evidence shows that tiny bits of RNA not used to make proteins actually play central roles in normal biology and in the development of cancers. "Scientists have known for a few years that production of these tiny RNAs, known as microRNAs, is o...

Once-dreaded leprosy 'replaced' by tuberculosis, say researchers

What caused leprosy ?a widely dreaded disease in medieval Europe ?to fade from the scene? By the 16th century, the scourge had practically disappeared there. Their conclusion is based upon th...

Researchers offer proof-of-concept for Altered Nuclear Transfer

Scientists at Whitehead Institute for Biomedical Research have successfully demonstrated that a theoretical--and controversial--technique for generating embryonic stem cells is indeed possible, at least in mice. The theory, called altered nuclear transfer (ANT), proposes that researchers first create genetically altered embryos that are unable to implant in a uterus, and then extract ste...

More>>

once at Biology Products

ATX Ponceau S red staining solution from Sigma-Aldrich

Description:Packaging: 6 bottles for 1 l ready-to-use-solution...
Company:Sigma-Aldrich

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. One mL stains 100 minigels. A 500 µL unit size (S-7564) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. 500 µL stains 50 minigels. A 1 mL unit size (S-7568) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

SYBR Green II RNA gel stain*10,000X concentrate in DMSO**special packaging* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. A 500 µL unit size (S-7564) and 1mL unit size (S-7568) are available....
Company:Molecular Probes (Invitrogen)

Murashige and Skoog basal salt solution with Gamborg's B5 vitamins, 10X concentrate from Research Organics, Inc.

Description:...
Company:Research Organics, Inc.

More>>

once at Biology Technology

Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume

by Varying the Final Elution Volume Eppendorf 5 Prime, Boulder, Colorado Perfect gDNA Blood Mini Kit protocol recommend...

Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume

by Varying the Final Elution Volume Eppendorf 5 Prime, Boulder, Colorado Perfect gDNA Blood Mini Kit protocol recommend...

Quantitation of Cabergoline at Extremely Low Plasma Concentrations with a Triple Quadrupole Mass Spectrometer

Nicola Hughes, Jean-Jacques Dunyach, 1Biovail Contract Research,Toronto,Ontario,Canada; 2Thermo Finnigan,San Jose,CA,USA; 3Therm...

UW prof makes laser for scanning lots of information at once

Researchers can derive information about a material based on its sensitivity to different colors. This laser system allows them to try a full range of color...

Benchmark Plus Microplate Reader: Quantitation of Protein Concentration Using Two Different Colorimetric Assay Kits, Rev A

Theresa Redila-Flores, Bio-Rad Laboratories, 2000 Alfred Nobel Drive,Hercules, CA 94547 USA The Bradford and Lowry assays are 2 colorimetric assays that are commonly used to quantitate protein concentration. Bio-Rads protein assay (catalog #500-0001), based on the Bradford dye-binding assay (Bradford 1976), measures t...

More>>

once at Biology Dictionary

Concentration gradient

<A href="http:/ / www.phschool.com/ science/ biology_place/ glossary/ c.html" tar...

once at Medicine News

Acupuncture for conception

There are many grueling and expensive options to explore for women who are trying to conceive the latest of it being Acupuncture. According to an article from the San Francisco Chronicle, older women are particularly favour acupuncture because they may have been through the other options. They usually face multiple problems when it comes to conception. A woman is born with a certain nu...

Ajanta Launches World's First Once-A-Day Nimesulide Oral Formulation

The Mumbai-based Ajanta Pharmaceuticals (APL) has launched its once-a-day 200mg controlled release nimesulide brand Nimlodi for arthritis. Nimlodi, which was developed by the Company through new drug delivery system, is the world's first once-a-day nimesulide brand for the treatment of arthritis. Ajanta, which manufactures both Allopathic and Ayurvedic medicines, developed this oral formu...

Time to re-assess lung donation concept

According to researchers, it may be possible to increase the supply of lungs for transplant.There is always a shortage of organs for transplantation.// Researchers in San Francisco and Nashville have been looking at the supply of lungs for transplant. They note that currently 80 per cent of lungs are rejected. That's a very high number. Could the criteria for selection be too strict?...

First head-to-head trials of once weekly Fosamax and Actonel therapies

The drug major Merck has launched the first two head-to-head clinical trials that compare the efficacy and tolerability of Fosamax (alendronate) once weekly 70mg and Actonel (risedronate) once-weekly 35mg. Fosamax and Actonel, both bisphosphonates indicated for the treatment of osteoporosis in post menopausal women are co-marketed by Aventis and Procter & Gamble through the Alliance for//...

Once-Daily Cipro(R) XR for Treating Complicated Urinary Tract Infections

Urinary tract infections (UTI) are often caused by bacteria and are frequently treated with antibiotics, such as fluoroquinolones. Fluoroquinolones have been recommended empirical therapy for treatment of complicated UTIs. Research indicates that Ciprofloxacin has high activity against E. coli that causes the majority of these infections. This new extended release formulation of ciproflox...

More>>

once at Medicine Products

Concepta Refraction Unit

Description:The only ergonomic work station of its kind with an optional built-in keratograph and flat-screen. The Concepta is a modern workstation for the examination and refraction of patients....
Company:Oculus, Inc.

Bausch & Lomb Concentrated Cleaner

Description:Bausch & Lomb concentrated cleaner is a sterile, concentrated homogeneous surfactant solution containing alkyl ether sulfate, ethoxylated alkyl phenol, tri-quaternary cocoa-based phospholipid and silica gel as cleaning agents....
Company:Bausch & Lomb, Inc.

Terrific Broth 10X Concentrate

Description:12% Tryptone, 24% Yeast Extract, 4.0% Glycerol. Supplied with 1 liter of 10x phosphate buffer (0190-1L)....
Company:Teknova, Inc.

Disposable Concentric Needle Electrodes

Description:Surgical-grade stainless steel disposable concentric needle with Trocar tip has an insulated platinum-alloy core and two attached 61-cm (24-in) lead wires. Needles sold in packages of 20....
Company:Cadwell Laboratories, Inc.

Disposable Detachable Concentric Needle Electrodes

Description:Surgical-grade stainless steel, detachable disposable concentric needle has a platinum-alloy core, color-coded cap, and a 2-mm (.08-in) brass plug connector. Needles sold in packages of 20. The 91-cm (36-in) shielded cable with 5-pin DIN connector is sold separately. The shielded cable is shipped nonsterile and may be autoclaved or disinfected (page 34). A starter kit containing two of each disp...
Company:Cadwell Laboratories, Inc.

More>>

once at Medicine Technology

Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis

LONDON, 2 July2007: Chi-Med, the Hutchison Whampoa backed pharmaceutical andhealthcare Group, today announces positive results for its Phase IIproof-of-concept study...

Labopharm to Present Poster on Dose Titration of Once-daily Tramadol at 3rd International Forum on Pain Medicine

- Article Discussing Pharmacokinetics and Dose Proportionality ofCompany's Once-Daily Tramadol to be Published in BiopharmaceuticsJournal - LAVAL, QC, June 29, 2007 /PRNewswire-FirstCall/ - Labopharm Inc.today announced that it will present a poster discussing the dosetitration of its once-daily formulation of tramadol at the 3rdInternational Forum on Pain Medicine to be held June 28 to J...

New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir

Minimal Weight Change Reported Unlike What Is Commonly Seen InInsulin Therapy CHICAGO, June 24, 2007 – Novo Nordisk today announcedresults of a new study that further demonstrated the safety andefficacy of insulin Levemir® (insulin detemir [rDNA origin]injection). Patients with Type 2 diabetes were able to adjusttheir own dosage of Levemir® and achieve improvements i...

Phase II Results Show Once-Daily Dosing of Human GLP-1 Analog Liraglutide, Brings Patients to A1c Target

New study demonstrates 75% of patients receiving highest doseachieves A1c with no associated hypoglycemia CHICAGO, June 25, 2007 /PRNewswire-FirstCall/ -- According tofindings presented today at the 67th Scientific Sessions of theAmerican Diabetes Association (ADA) in Chicago, Illinois, theinvestigational treatment liraglutide, a once- daily dose of humanGLP-1 analog under development by...

Phosphagenics Announces Positive Proof of Concept Results from Studies Utilizing Company's Dermal Drug Delivery Technology

MELBOURNE, Australia, June 25, 2007 /PRNewswire-FirstCall/ --Phosphagenics Limited (AIM: PSG) announced today positive resultsfrom pre-clinical studies of its TPM-02 dermal drug deliverytechnology formulated with retinoic acid, a leading topicaltreatment for severe acne and an active ingredient used inanti-aging cosmetics. The proof of concept studies showed a three-fold increase i...

More>>

once at Medicine Definition

Dose concentration

that contains it, often measured in units of <a...

once at Medicine Dictionary

Conception

, marked by implantation of the blastocyst...