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observed in Medical News

Keryx Biopharmaceuticals, Inc. Announces Poster Presentations Highlighting Observed Clinical Activity of KRX-0401 (Perifosine) to be Presented at the Upcoming American Society of Hematology Meeting in Atlanta, Georgia

Data on Perifosine in the Treatment of Patients with Relapsed/Refractory Multiple Myeloma to be presented on Saturday, December 8th at 5:30pm NEW YORK, Dec. 7 /PRNewswire-FirstCall/ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX ) today announced that abstracts related to KRX-0401 (Perifosi...

Differences observed between black and white women in use of breast cancer therapy

A new study finds treatment for breast cancer differs between African-American women and white women, though the differences are partly dependent on insurance type. The study appears in the November 15, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society. Dr. Mousumi B...

The New England Journal of Medicine Publishes EURIDIS/ADONIS Study Results Showing Dronedarone Maintained Sinus Rhythm in Patients With Atrial Fibrillation or Flutter With no Observed Pro-Arrhythmia

PARIS, Sept. 5 /PRNewswire-FirstCall/ -- Sanofi-aventis announced the publication of two international trials -- EURIDIS and ADONIS -- which demonstrated that dronedarone (MULTAQ(TM)), a new anti-arrhythmic agent in late stage development, is significantly more effective than placebo in mainta...

50 years of hairy-cell leukemia research to be observed

COLUMBUS, Ohio In 1958, Ohio State University cancer researcher Dr. Bertha Bouroncle first identified a deadly disease now known as hairy-cell leukemia, a once fatal disease that can now be effectively treated. Now, 50 years later researchers from across the globe are gathering for a sympos...

Scientists Observed Live Cell Migration

Johns Hopkins researchers have found a way to directly observe cell migration -- in real time and in living tissue. Cell, the scientists say their advance could lead to strategies for controlling both normal growth and the spread of cancer, processes that depend on the programmed, organized moveme...

Vitamin D Deficiency Observed in Breast Feeding Mothers

In a study published in Clinical Pediatrics, it is reported that breast feeding mothers may be deficient in vitamin D. If this deficit is taken care of, their children// may not be affected by vitamin D deficiency disorders. Joyce M. Lee and his team belonging to University of Michigan conducte...

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observed in Medical Technology

Keryx Biopharmaceuticals, Inc. Announces Poster Presentation Highlighting Observed Clinical Activity of KRX-0401 (Perifosine) at the American Society of Clinical Oncology Meeting in Chicago, Illinois

Phase 2 Results of Perifosine in the Treatment of Patients with Relapsed/Refractory Waldenstrom's Macroglobulinemia to be presented Tomorrow, Tuesday, June 3rd at 12:00pm in Room E450a NEW YORK, June 2 /PRNewswire-FirstCall/ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX ) toda...

Nektar Terminates All Negotiations With Potential Partners for Inhaled Insulin; Increased Number of Lung Cancer Cases Observed in Ongoing Clinical Studies of Inhaled Insulin Patients

SAN CARLOS, Calif., April 9, 2008 /PRNewswire-FirstCall/ -- Nektar Therapeutics (Nasdaq: NKTR ) announced today that it has ceased all negotiations with potential partners for its inhaled insulin programs as a result of new data analysis from ongoing clinical trials conducted by Pfizer Inc. A...

Labopharm files New Drug Submission with Health Canada for novel antidepressant

...rcent in the trazodone group. In the trazodone group, four percent of patients discontinued treatment due to somnolence or sedation. The drop out rate observed in this study is comparable to drop out rates in typical depression studies. The results of this study are found in the May 2009 issue of Psychiatry (...

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...s, such as being thirsty all the time, having to urinate or "pass urine" more often than usual, or feeling weak or hungry. Weight gain has been observed with INVEGA((R)) SUSTENNA(TM) and other atypical antipsychotic medications. If you notice that you are gaining weight, please notify your doctor. ...

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

...stically significant improvements compared with baselines were also observed in platelet and spleen sizes, and nominally significant improvements were observed in liver size at this dose. Results were clinically important as defined by standard criteria and consistent with the previously published Phase I/II ...

Pharmasset Reports Positive Preliminary Antiviral Data With PSI-7851 for the Treatment of Hepatitis C

...7851 Antiviral Activity Summary Preliminary Antiviral Response observed Following PSI-7851 Administered as Monothe... conducted studies involving our product candidates will not be repeated or observed in ongoing or future studies involving our product candidates, the risk tha...
observed in Medical Products

Vasopressin (AVP) RIA Test

Description:... in which the renal tubules fail to reabsorb solute-free water. In contrast, sustained, elevated levels of AVP in the absence of any known stimuli are observed in syndrome of inappropriate antidiuretic hormone (SIADH) and can result from a number of factors including secretion of AVP by malignancy, disorders ...
Company:Diagnostic Systems Laboratories, Inc.

Aldosterone RIA Test

Description:...sure and blood volume. Aldosterone also enhances urinary potassium and hydrogen (acid) excretion. Abnormally high plasma aldosterone levels are observed in primary hyperaldosteronism, in which renin levels are low, blood pressure is elevated and potassium levels are decreased [3,5]. Abnormally high ald...
Company:Diagnostic Systems Laboratories, Inc.

Leptin IRMA Test

Description:...hat may occur. Some examples of rapid changes in leptin levels would be starvation and forced feeding where changes within 24 to 48 hours are readily observed in serum leptin concentrations. Similarly, there are rapid declines postpartum suggesting that something other than the amount of adipose tissue may ...
Company:Diagnostic Systems Laboratories, Inc.

Leptin ELISA Test

Description:...hat may occur. Some examples of rapid changes in leptin levels would be starvation and forced feeding where changes within 24 to 48 hours are readily observed in serum leptin concentrations. Similarly, there are rapid declines postpartum suggesting that something other than the amount of adipose tissue may ...
Company:Diagnostic Systems Laboratories, Inc.

ACTH RIA Test

Description:...ic disorders and in certain systemic infections. Elevated plasma levels are observed in patients with ACTH-secreting pituitary (Cushings disease) and non-pituit...al disorders affecting cortisol secretion. Increased ACTH secretion is also observed in pregnancy, during the menstrual cycle and stress. Buckingham JC et a...
Company:Diagnostic Systems Laboratories, Inc.

PVC Multichannel Solution Basins

Description:...f the solution. The corners have pouring lips to dispose of the excess solution. Basin capacity is 55 mL. PVC material allows the solution level to be observed through the sides of the basin. New design enables easy removal from package for immediate use. Non-sterile. Dimensions: 60 mm L x 138 mm W x 27 mm H...
Company:PGC Scientifics
observed in Medical Definition

Depolarization-induced suppression of inhibition

...ence support the role of the CB1 receptor in DSI. This receptor is distributed very widely throughout the brain, covering all areas where DSI has been observed (Herkenham et al. 1990). The CB1 receptor also appears to be expressed mainly on GABA-ergic pre-synaptic terminals, making it an excellent candidate...

Cryostasis (clathrate hydrates)

...ce and bound water. In general, this process is not reversible to the point of restoring the tissues to life, although there are occasional exceptions observed in nature (vitrifying polyols (i.e., insects, amphibians), thermal hysteresis proteins (insects, fish). [4] [5] Clathrate hydrates are a clas...

Medicine

...t said something must be so, then that was the way it was, and anything one observed to the contrary was an anomaly (which was paralleled by a similar shift in ... arsphenamine / Salvarsan discovered by Paul Ehrlich in 1908 after he observed that bacteria took up toxic dyes that human cells did not. The first major ...

Mumijo

...Aristotle and Avicenna as a remedy with antiseptic and general stimulant properties used in Caucasus mountains . Most scientists agree that people observed wounded animals frequenting caves with mumijo and so discovered the substance. Similar substances are used for medicinal purposes throughout Tibet. ...

Ultradian

... factors that may also play a role in onset and severity of Bipolar disorder. The same kindling effect that is present with seizure disorders has been observed in early onset cases of Bipolar Disorder. Results are inconclusive at this time. Ultradian states in Bipolar Disorder are different from rapid cyc...
observed in Medical Dictionary

Waardenburg syndrome

...afness and facial bone defects and by variation in pigmentation Waardenburg syndrome (WS) is an inherited disorder often characterized by ... observed characteristic of Waardenburg syndrome is two differently colored ... Article describes Waardenburg syndrome , its symptoms, diagnosis, and...

Vasoconstriction

...ain stem, causing reflex changes in the heart rate with. Wolff suggested that the vasoconstriction occurring during the aura involves ... He observed that cerebral vasoconstriction had usually ended before the ... Vasoconstriction Christina Care Health System ... Vasoconstriction may be .....

Toeing in

...ausing the toes to point in. ... There are three common causes of in - toeing . ... ... Words: In - toeing , genu varus, ... ambulation, she was observed toeing - in with her left foot ... In - toeing is a position where the feet are pointing inward, ... In - toeing means that the foot ot fe...

Tick bites

...seases : An Overview ... who skin wild rabbits, more than half of all cases result from tick bites . ... ... acquiring Lyme disease from an observed tick bite is only 1.2 to 1.4 percent, ... one-third of people recall the tick bite that gave them Lyme disease. ... Tick bite informat...

Testes

...of the resulting... Human ectopic xenografting was performed using adult testes . ... In comparison to control testes , minor disorganization is observed after cooling. ... Genome-wide expression of azoospermia testes demonstrates a specific profile and ... 45 to 207 million spermatozoa produced p...

Simian crease

...mian crease " is not ... Partial Simian crease was significantly increased. ... A significantly high frequency of Simian Crease was also observed on palms of ... simian crease n A single crease across the palm produced from the fusion of proximal and distal palmar creases , seen i...
observed in Biological News

Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time

Extensive death of nerve cells leads to severe dementia in patients with Alzheimer's disease. Until now, it has only been possible to investigate the neuronal devastation in post mortem animal models, and by using complicated methods. Researchers at the German Center for Neurodegenerative Disease ...

Recombination protein dynamics observed with single monomer resolution

Using a sensitive, single-molecule measurement technique, researchers at the University of Illinois at Urbana-Champaign have observed the life cycle of RecA, a protein that plays a major role in repairing damaged DNA. The protein forms a filament, which grows and shrinks primarily by one monomer ...

Bladder cells feel stretch

...ell responses upon stretch stimulation, which mimics bladder distension. Upon stretch stimulation, robust Ca2+ influx and following ATP release were observed in urothelial cells. These phenomena were almost completely attributed to TRPV4 activation, since such responses were eliminated by a TRPV4 inhibitor ...

AGU journal highlights -- Aug. 6, 2009

...gnificant reduction in Southern Ocean carbon uptake, in good agreement with observed trends. The simulations show that ozone depletion, combined with increased ...ironmental processes, whether current climate models successfully replicate observed patterns in dimming and brightening, and how dimming and brightening may ev...

Carnegie Mellon's Jean VanBriesen leads research team on Monongahela River

...osal at wastewater treatment plants along the Monongahela in 2008 is suspected as a contributing factor in high levels of total dissolved solids (TDS) observed in the river. Carnegie Mellon researchers will work with the River Alert Information Network (RAIN), a regional association of d...

Mary had a lot of lambs: Researchers identify way to accelerate sheep breeding

...ually responsible for the trait. "Breeding out of season is a complex trait," Mateescu said, "so there are a lot of genes controlling it." Mateescu observed the phenotype the physical expression of the gene in the researchers' flock during a postdoctoral fellowship at Cornell. "In this case, we're tal...
observed in Biological Technology

Growth spurts

...mately the same size and shape. "Coalescence events have been previously observed in flask synthesis of colloidal nanocrystals and has been considered detrim...oscope (TEM) are brought to bear on a liquid cell that allows liquids to be observed inside a vacuum, enables the visualization of single nanoparticles in solut...

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

...in Japan. Pirfenidone was safe and generally well tolerated in both CAPACITY studies. There was no difference in SAEs and fewer deaths were observed with pirfenidone compared to placebo. Adverse events were comparable to previous clinical studies of pirfenidone. New, pre-specified expl...

OncoGenex Reports Second Quarter 2009 Financial Results

...docetaxel in a randomized phase 2 trial was 23.8 months compared to 16.9 months for patients treated with docetaxel alone -- a 6.9 month observed survival advantage for the OGX-011 arm. The unadjusted hazard ratio (HR), a measure used to compare the death rates between treatment gr...

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

...imothy Hoey, Ph.D., Vice President, Cancer Biology of OncoMed Pharmaceuticals and a co-author of the paper. "In models of colon and breast cancer, we observed that treatment with OMP-21M18 significantly decreased the proportion of cancer stem cells found in tumors compared to chemotherapy alone. In addition...

Angiotech Pharmaceuticals, Inc. announces financial results for the second quarter ended June 30, 2009

...crease their order levels later in 2009, however, there can be no assurance that we will record sales of surgical needles to these customers at levels observed in prior periods. Royalty Revenue. We generate significant revenue derived from royalties paid to us by partners that develop, market and sell pr...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results

...g the improved methodology demonstrated that all of the evaluable baseline samples had detectable interstitial capillary GL-3 and that reductions were observed in eight of the nine responders. It is expected that approximately 30 clinical sites worldwide will participate in this trial. Pli...
observed in Biological Products

TriEx Insect Expression Medium from Novagen

Description:... pTriEx baculovirus constructs. This cell/medium combination has been selected based on rapid, vigorous cell growth and high protein expression levels observed specifically with baculoviruses derived from the pTriEx-1.14 vectors. Please note that our Ready-Plaque Sf9 Cells and BacVector Insect Cell Medium are...
Company:Novagen

ProFound Label Transfer Sulfo SBED Protein:Protein Interaction Reagent from Pierce Biotechnology, Inc.

Description:...or biotinylated prey protein on a Western blot. • Label transfer is an in vitro method for discovering or verifying an interaction that was observed by way of another technique such as the in vivo yeast 2-hybrid method or by in vitro methods such as co-immunoprecipitation or pull-down assays. &bu...
Company:Pierce Biotechnology, Inc.

2,7-Dichlorofluorescein (Fluorescence Reference Standard) from AnaSpec

Description:... pH-dependent fluorescence; Maximum intensity observed in basic solutions....
Company:AnaSpec

ApoDIRECT DNA Fragmentation Assay Kit from MBL International

Description:...rase (TdT) to catalyze incorporation of fluorescein-12-dUTP at the free 3-hydroxyl ends of the fragmented DNA. The fluorescein-labeled DNA can then be observed by fluorescence microscopy or analyzed by flow cytometry....
Company:MBL International

MitoLight Mitochondrial Apoptosis Detection Kit from CHEMICON

Description:... cytoplasm, fluorescing green (l em = 527-530 nm), providing a ready discrimination between apoptotic and nonapoptotic cells. The fluorescence can be observed by fluorescence microscopy using a band-pass filter (detects FITC and rhodamine) or analyzed by flow cytometry using FITC channel for green monomers (...
Company:CHEMICON

8-iso-13,14-dihydro-15-keto Prostaglandin F2alpha from Cayman Chemical

Description:...oprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into rabbits. Early in the infusion (within 10 minutes) 8-iso-13,14-dihydro-15-keto PGF2α was a signifi...
Company:Cayman Chemical
observed in Biological Definition

Abiogenesis

...istotle explicitly taught this form of abiogenesis, and laid it down as an observed fact that some animals spring from putrid matter, that plant lice arise fr...nued to postulate a "primordial archebiosis", in which the living organisms observed in the present world had originally arisen in a series of stages from non-l...

Apoptosis

...ble membrane that surrounds the nucleus still appears complete; however, as observed by Kihlmark and colleagues, specialized caspases have already advanced in t...o, that while the previous stage of initial chromatin condensation has been observed in nonapoptotic forms of programmed cell death, this advanced stage (called...

Biodiversity

...gists, environmentalists, political leaders, and concerned citizens world-wide. This use has coincided with the expansion of concern over extinction observed in the last decades of the 20th century. Contents showTocToggle("show","hide") 1 Biodiversity definitions 2 Origin of life and bi...

Bacterium

...cellaneous 8 See also 9 References 10 Further reading 11 External links History and taxonomy The first bacteria were observed by Antony van Leeuwenhoek in 1683 using a single-lens microscope of his own design. The name bacterium was introduced much later, by Ehrenberg...

Cancer

... risk for a number of different cancers; however, it is not currently known which specific components of fruits and vegetables are responsible for the observed associations or if healthy diets are simply associated with other beneficial interventions, e.g., exercise. Contrary to expectation, randomized trials...

Chromosome

...t possess histones or nuclei. In its relaxed state, the DNA can be accessed for transcription , regulation, and replication . Chromosomes were first observed by Karl Wilhelm von Ngeli in 1842 and their behavior later described in detail by Walther Flemming in 1882 . In 1910 , Thomas Hunt Morgan pr...
observed in Biological Dictionary

Zona pellucida

...acellular transparent envelope surrounding the mammalian oocyte. ... FTIR of a Mixture of Porcine Zona Pellucida Proteins. ... Surprisingly, we observed that zona pellucida of human fertilised oocytes, ... Human zona pellucida were mechanically isolated by disrupting oocytes or embryos ... ...

Tropism

..., CXCR4, or dual/mixed. ... Tropism & HIV Resources. What is Trofile™ How to Order Trofile™ CCR5 Antagonist & Trofile™ ... Other commonly observed tropisms include galvanotropism or electrotropism, ... The term tropism was formerly applied only to the responsive movements of fixed ... Maxa...

Trophoblast

...w articles on Trophoblast . Articles on Trophoblast in N Eng J Med, ... A laymen's explanation of the cancer theory that matches more of the observed characteristics of cancer that any other theory. trophoblast . Definition from Wiktionary, a free dictionary. Jump to: navigation, search ... wi...

Tet resistance

...rminant, tet (E) ... Although tet (M) is widely distributed and provides functional resistance to ... Residual TET resistance had also been observed when the corresponding glycine ... efflux protein Tet (K) determined by antibacterial resistance gene fusions. ... ... level tetracycline ...

Telomere

... The Telomere Book by David Kipling; 1995. Read The Telomere at Questia library. ... However, this mode of telomere replication has yet to be observed for eukaryotic ... ... on why this elongation is necessary see Telomere shortening. ... Identification of a specific telomere terminal transfer...

Spirochetes

...ochetes are known to activate a variety of cell types in vitro, we ... With regard to the two spirochetes , it seemed likely that differences observed ... and diversity of functional classes of proteins between the two spirochetes . ... Pathogenic spirochetes in the genus Borrelia are trans...
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