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Angelina Jolie Poses in Nude

Angelina Jolie the famous actress and wife of Brad Pitt has commissioned US artist Don Bachardy to paint three portraits of her to celebrate the different stages of her pregnancy. Angelina had asked Mr.Bachardy not to talk to anyone about her request. About the portrait. The paint...

Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

...ficity of the ablated retargeted vector towards human pancreatic cancer cells was enhanced almost 10-fold in vitro. In a subsequent in vivo study of a nude (nu/nu ) mouse model however, no increased adenoviral targeting to subcutaneously growing human pancreas cancer nodules was seen upon injection into t...

Stemedica Medical Team Cautions Patients About Stem Cell Therapy & Comments on PLoS Medicine Article

...cess should be. For example, there was no data provided relating to tumorgenicity, toxicity, or bio-distribution testing of the manufactured cells in nude mice which is a mandatory requirement as a first and critical step to assessing cell safety." "Stemedica is committed to a manufacturing...

The Largest and Most Comprehensive College Dating and Sex Survey Uncovers Surprising Behaviors of Students In and Out of the Bedroom

... likely to pass out from alcohol than non-vegans. "These statistics point to a shift in norms and the dismantling of taboos. Whereas "sex tapes" and nude photos were once considered the domain of porn, it's now becoming normal to post online for all the world to see. Novelty, exhibitionism and the searc...

Oncology Clinical Research Scientist Recommends a Nuanced Preclinical Study Process to Speed Drug Development

...- and radiation-adjunct therapies, gene therapies, adoptive cell transfers and other leading edge technologies. He has himself worked with SCID-hu and nude immune deficient animals, many genetically altered (transgenic and knockout) and mutant mice in most common strains of mice. His experience extends to...

New study shows potential to treat or prevent viral cancers

...loping radioimmunotherapy of infectious diseases and cancers. The study involved treating experimental cervical cancer and hepatocellular carcinoma in nude mice with antibodies to respective viral antigens expressed on these tumors. The antibodies were radiolabeled with 188-Rheniuma powerful beta-emitting...

Monoclonal antibody Hb3: A marker for colon cancer progression or as a therapeutic target?

...ult of gene amplification. The overexpression of an Np63 isoform in Rat 1A cells increases colony growth in soft agar and xenograft tumor formation in nude mice. It is hypothesized that agrNp63 alpha promotes survival and the maintenance of proliferative capacity in both epithelial stem cells and cancer c...

Panacea Pharmaceuticals Announces Selection of PAN-622 - A Fully Human Sequence Monoclonal Antibody Against HAAH - As Its Lead Cancer Therapeutic Product

...iver cancer as measured by inhibition of tumor growth, and thus has been selected as Panacea's lead anti-cancer drug candidate. In recent experiments, nude mice were injected subcutaneously with a human liver cancer cell line and tumors were allowed to grow for 3 days prior to the initiation of treatment....

Stem Cells from Human Fat Tissue to Hunt for and Kill Cancerous Tumours

...eep out into the tumour, producing a lethal by-stander effect. Researchers first injected the engineered mesenchymal stem cells, then 5-FC in nude mice, animals with an inhibited immune system, engrafted with human colon cancer. The study found that tumour growth was inhibited by up to 68...

Marilyn Monroe was Just too Hygienic for Clark Gable!

... would be described as a form of irritable bowel syndrome," he adds. To add to all this was the fact that Marilyn "rarely bathed, slept in the nude and ate a lot in bed - shoving what was left on her plate under the sheets before going to sleep." Bret's biography of Gable hits bookstores ...
nude in Medical Technology

Local Research Foundation Achieves Milestone in Fight Against Cancer

...y against a wide array of human cancers growing in nude mice with a striking lack of toxicity. CZ48 is als...innovated the use of nude mice in cancer research. nude mouse tests are now the final, non-human studies r...nts. Many scientists around the world consider the nude mouse one of the 20th century's most significant b...

Bioheart Reports Promising Results From Preclinical Study of Adipose-Derived Acute Cell Therapy

... cardiomyocytes (heart cells) subsequent to injection of ADSCs following heart attack, or acute myocardial infarction (AMI). The study consisted of 99 nude rats* randomized into one of six treatment arms (including a control group receiving injection-vehicle containing cell media only). ADSCs for the trea...

Resveratrol Longevity Science Makes Dramatic U-Turn, But Resveratrol Supplements Remain Unchanged

...esveratrol combined with quercetin or other small molecules. [Combined resveratrol, quercetin, and catechin treatment reduces breast tumor growth in a nude mouse model. Translational Oncology 2008 March; 1(1):19-27; Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with c...

Tumor Eradication Article Published by Cancer Research

...alay, PhD, an internationally-recognized scientist who founded Genelux Corporation in 2001. The article, titled "Eradication of Solid Human Tumors in nude Mice with an Intravenously Injected Light-Emitting Oncolytic Vaccinia Virus," documents animal studies that have resulted in complete eradication of h...

Tapestry Pharmaceuticals to Present Data on TPI 287 at the 2007 AACR Annual Meeting

...entation entitled, "TPI 287 crosses the blood brain barrier and contributes to antitumor activity in the U251 glioblastoma intracranial tumor model in nude mice." The poster (#1441) will be presented Sunday, April 15, 2007 from 1:00 - 5:00 p.m. at the Experimental and Molecular Therapeutics 8 session. A...

Cytokinetics Announces Non-clinical Data to be Presented at the 2007 AACR Annual Meeting

...3295: Abstract #1522: GSK-923295, a Potent and Selective CENP-E Inhibitor, Has Broad Spectrum Activity Against Human Tumor Xenografts in nude Mice. (Poster displayed on Sunday, April 15, 2007, 1:00 PM - 5:00 PM, PT, Poster Section 31, Poster Board 8.) Abstract #3179: Detai...

DNA Therapeutics Reports a Novel Mechanism of Action and a Biomarker of its Lead Molecule Dbait That Open an Innovative Pathway-Targeting in Molecular Cancer Therapy

...ept work was presented last November at the 18th EORTC-NCI-AACR Symposium "Molecular Targets and Cancer Therapeutics" (Prague): the median survival of nude mice grafted with human tumor cell lines treated by intra-tumoral injection of Dbait, in association with radiotherapy, is significantly increased in ...

Onconova Therapeutics Announces Presentation of Clinical and Non-Clinical Results for Its Lead Compound ON 01910.Na at American Association of Cancer Research Conference in Los Angeles

...f Oxaliplatin" by J. Jiang, Y. Li, L. Wang, J. Qu, P. Mannam, E. P. Reddy and James F. Holland (Mount Sinai School of Medicine, New York). Employing a nude mouse model system and human liver, hormone refractory prostate, melanoma, pancreatic and colon tumors, single agent activity of ON 01910.Na was shown...

AEterna Zentaris Discloses In Vivo Data for its GHRH Antagonist JMR-132 at the AACR Annual Meeting in Los Angeles

...he treatment of early and metastatic breast cancer. Binding sites were found for GHRH in the MX-1 human breast cancer cell line. The treatment of nude mice bearing MX-1 xenografts with JMR-132 at the dose of 10 (micro)g/day s.c. significantly (p<0.05) inhibited tumor growth, as shown by a 62.9% decre...

Gloucester Pharmaceuticals Reports on Romidepsin and Erlotinib Combination in Non-Small Cell Lung Cancer Presented at American Association of Cancer Research Annual Meeting

... vivo arm of the study H1299 xenografts were inoculated subcutaneously into nude mice. The developing tumors were treated with either romidepsin, erlotinib ...ines by induction of profound apoptosis. This synergy was also shown in the nude mice xenografts but was not observed in epidermal growth factor (EGFR) muta...
nude in Biological News

The nude mouse tale: Omega-3 fats save the life of a terminal cancer patient

Ron Pardini is not a medical doctor. Yet he is seen as a hero by his cancer-stricken neighbor, "D.H." Pardini helped the 78-year-old after D.H. was diagnosed with terminal lung cancer. "In 2000 he was told by his doctor he had only a few months to live," said Pardini, a professor of biochemistry ...

SIRT1 takes down tumors

...l groups from c-Myc, hastening its breakdown. To test SIRT1's effects on tumor growth, the researchers implanted cancerous cells expressing c-Myc into nude mice that lack immune defenses. Boosting production of SIRT1 blocked tumor formation. How deacetylation of c-Myc sparks its destruction is still a ...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...that if the lytic peptide has no interaction with the membrane it is targeting, it cannot kill," Leuschner says. The research group next looked at nude mice ?mice lacking immune systems ?that carried xenografts of human breast cancer. In another proof-of-concept study, they found that if a nanoparticl...

Scientists turn tobacco against cancer

...ied from tobacco leaves could recognize, or bind to, human colorectal cancer cells. Next, they grafted human colorectal cancer cells onto the backs of nude mice ?mice stripped of their immune systems, and subsequently injected the animals with the plant-derived antibodies. Then they watched for tumor grow...

Use of PET can reduce, may eliminate more strenuous drug development trials with animals

..., Bio-X Program, Stanford University School of Medicine, Stanford, Calif. * "GRP Receptor-Targeted PET of a Rat Pancreas Carcinoma Xenograft in nude Mice With a 68Ga-Labeled Bombesin(6?4) Analog" was written by Jochen Schuhmacher, Ph.D., department of diagnostic and therapeutic radiology, German Ca...
nude in Biological Technology

Dr. Gail Naughton Speaks on Histogen's Business Plan and the Rise of Bioaesthetic Medicine during Commercial Translation of Regenerative Medicine

...lone in two preclinical models. In the CAM model (chollioallantoic membrane) tumor mass was significantly reduced by the presence of ExCeltrix. In the nude mouse model, cells with ExCeltrix showed little to no tumor growth, in comparison to the control which did form palpable tumors. Dr. Gail Naughto...

Oncolytics Biotech Inc. Announces 2008 Third Quarter Results

...a preclinical study demonstrating that a single IV administration of ReoT3D can result in substantial tumor growth delay in melanoma-bearing nude mice; - The grant of the Company's 29th U.S. patent, which covers methods of selectively removing cancer cells ex vivo from blood stem cells ...

Oncolytics Biotech Inc. Collaborators Present Reovirus and Melanoma Research at EORTC-NCI-AACR Symposium

...n all dose groups. The investigators concluded that a single IV administration of reovirus led to substantial tumor growth delay in melanoma-bearing nude mice, and the extent of acute phase reovirus replication in tumor tissues appeared to predict the subsequent tumor response. This proof-of-principle s...

Oncolytics Biotech Inc. Collaborators to Present REOLYSIN(R) Clinical Trial

... is scheduled to deliver a poster presentation entitled "In Vivo Efficacy and Replication Dynamics of Intravenously Administered Oncolytic Reovirus in nude Mice Bearing Human Melanoma Xenografts" at the EORTC-AACR-NCI Symposium on Molecular Targets and Cancer Therapeutics. About Oncolytics Biotech Inc. ...

Medarex Announces Presentations at Annual Meeting of the American Association for Cancer Research

...cheduled for Tuesday, April 15, 2008 at 8:00 a.m. -- "Mechanism of activation of a human anti-CD70 antibody-MGBA conjugate and efficacy in a nude rat model of renal carcinoma" (Abstract #4057, Immunoconjugates, Peptides, and Protein Therapeutics Session) - Poster session scheduled for Tu...

RNAi as a Tool for Mammalian Gene Analysis: Applications of siRNAs

...s of HCC cells and blocked cell proliferation. In addition, the cyclin E siRNA inhibited HCC tumor growth in nude mice demonstrating the potential for creating drugs targeting cyclin E. Pathway Analysis Another key ...
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