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nonhuman in Medical News

Researchers find first conclusive evidence of Alzheimer's-like brain tangles in nonhuman primates

Researchers at the Yerkes National Primate Research Center, Emory University, have discovered the first conclusive evidence of Alzheimer's-like neurofibrillary brain tangles in an aged nonhuman primate. The unprecedented finding, described in the online issue of the Journal of Comparative Neurolog...

AVMA Urges Outlawing Trafficking of Chimps, Monkeys and Nonhuman Primates and Pets

SCHAUMBURG, Ill., March 11 /PRNewswire-USNewswire/ -- Citing concerns about the spread of disease and injury, inhumane treatment of animals, and ecological damage, Dr. Gail Golab, PhD, DVM, director of the American Veterinary Medical Association (AVMA) Animal Welfare Division, spoke on the dan...

Yerkes researchers propose ambitious new strategies for AIDS vaccine research

... simian immunodeficiency viruses (SIVs) in African nonhuman primates, they propose an additional new approach ...essons learned from studying SIVs in their natural nonhuman primate hosts may provide a path to an effective A...IDS vaccine. SIVs are found exclusively in African nonhuman primate species and represent the original source ...

K-State Researcher, Collaborators Study Virulence of Pandemic H1N1 Virus; Work at K-State Would Protect Pig Industry If the Virus Jumps to Swine Populations

...urposes as controls to validate our testing systems." The researchers also studied the virulence of two strains of the pandemic H1N1 virus in a nonhuman primate model as a way to predict how the strains would affect humans. Comparing an isolate from California with one from Mexico, Richt and his collab...

Yerkes researchers use eye tracking to detect mild dementia in humans

...kes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive i...ntific understanding and to improve the health and well-being of humans and nonhuman primates. Today, the center, as one of only eight National Institutes of He...

College Kids and Monkeys About Equal on Math

...bjects without actually counting them. It might come as no surprise that nonhuman primates have some fundamental sense of numbers. "There are all sorts of reasons why number would be useful for nonhuman animals in the wild," Brannon said. "In foraging situations, animals need t...

Pre-verbal number sense common to monkeys, babies, college kids

...ntal sense of number without language should come as little surprise, Brannon says. "There are all sorts of reasons why number would be useful for nonhuman animals in the wild. In foraging situations animals need to make decisions about how long to stay in a given patch of food and when to move on," Brann...

Color Red Makes Men Amorous

...cal roots, said the researchers, who noted that previous studies found that nonhuman male primates are particularly attracted to females displaying red. For exa...o males. "Our research demonstrates a parallel in the way that human and nonhuman male primates respond to red," the study authors concluded. "In doing so, o...

Psychological study reveals that red enhances men's attraction to women

...red more likely stems from deeper biological roots. Research has shown that nonhuman male primates are particularly attracted to females displaying red. Female ...t males. "Our research demonstrates a parallel in the way that human and nonhuman male primates respond to red," concluded the authors. "In doing so, our fin...

Researchers develop first transgenic monkey model of Huntington's disease

...wide range of diseases using non human primate models. Yerkes primate center is an ideal place to carry out this work because of its expertise in nonhuman primate transgenesis, non-invasive neural imaging, and experience with behavior assessment, said Dr. Harding. ...
nonhuman in Medical Technology

Vaxfectin-formulated Measles DNA Vaccine Elicits Long-term Protection and Sterilizing Immunity in Nonhuman Primates

SEATTLE, May 31, 2007 /PRNewswire-FirstCall/ -- Vical Incorporated today announced that a measles DNA vaccine formulated with the company's Vaxfectin(TM) adjuvant elicited protective levels of neutralizing antibodies in juvenile (1 - 2 year old) nonhuman primates confirmed by complete protection f...

U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant

... from the dengue-1 (DEN-1) virus. Following successful challenge testing in nonhuman primates, NMRC conducted a Phase 1 trial of the unadjuvanted monovalent vac...ll four serotypes of dengue, and formulated with the Vaxfectin(R) adjuvant. nonhuman primate immunogenicity and challenge data with the tetravalent DNA vaccine,...

Research Attributes Lack of HIV/AIDS Vaccine to Use of Chimpanzees

...appeared to increase vulnerability to HIV infection in human clinical trial participants, though the vaccine had proven safe and effective in tests in nonhuman primates. Yet some scientists are calling for a return to the use of chimpanzees, despite their previous failings. Other scientists doubt that a ret...

Karolinska Institutet to Test Vical's Vaxfectin(R) Adjuvant With Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

...ccines. Vaxfectin(R)-formulated DNA vaccines have demonstrated good tolerability and significant immune responses in multiple animal models, including nonhuman primates, and recently underwent successful initial human testing with the company's H5N1 pandemic influenza DNA vaccines. Vaxfectin(R) has also demon...

Karolinska Institute to Test Vical's Vaxfectin(R) Adjuvant with Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

...ccines. Vaxfectin(R)-formulated DNA vaccines have demonstrated good tolerability and significant immune responses in multiple animal models, including nonhuman primates, and recently underwent successful initial human testing with the company's H5N1 pandemic influenza DNA vaccines. Vaxfectin(R) has also demon...

Vical Demonstrates Dose-sparing of Protein-based H5N1 Influenza Vaccine With Vaxfectin(TM) Adjuvant

...eutralizing antibodies in infant (6 - 10 week old) nonhuman primates confirmed by complete protection followin...unced similar results in juvenile (1 - 2 year old) nonhuman primates. Both measles studies were conducted in c... In the recently completed measles study in infant nonhuman primates, neutralizing antibody levels exceeded th...

Vical's Vaxfectin Adjuvant Achieves Dose-Sparing Effect With Seasonal Influenza Vaccine

...DNA vaccines, and Vaxfectin(TM)-formulated DNA vaccines have demonstrated good tolerability and adjuvant activity in multiple animal models, including nonhuman primates. The Fluzone(R) data suggest that Vaxfectin(TM) could provide a dose-sparing effect with the government-stockpiled H5N1 pandemic influenza va...
nonhuman in Medical Dictionary

Uvea

...om the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word games. Notes on ophthalmology involving nonhuman animals ... The uvea (uveal tract) is the vascular tunic of the eye and consists of the iris, ... Information about uvea in the free onlin...

Sclera

...es you from the pupil to the retina and beyond. ... Think of the sclera as your eyeball's outer coat. ... Notes on ophthalmology involving nonhuman animals ... The sclera makes up most of the fibrous tunic of the ... Acquired Abnormalities of the Sclera . Ectasia ... Sclera have a blue, p...

Parainfluenza virus

... to respiratory ... Collins PL, Chanock RM, McIntosh K. Parainfluenza viruses . ... Attenuation of bovine parainfluenza virus type 3 in nonhuman primates and its ... Serological studies of parainfluenza type 3 virus , bovine adenovirus type 3 and ... Overview: Parainfluenza viruse...

Leukocytes

...d in the absence of the masking effects of light-dark and sleep-wake cycles, correlates with habitual sleep ... Notes on ophthalmology involving nonhuman animals ... and contains leukocytes and lysozymes (Moore ... Lysozymes and leukocytes provide antibacterial activity. ... ...

Ebola

...after a river in the ... The fifth, Ebola -Reston, has caused disease in nonhuman primates, but not ... Fact sheet including transmission methods, sympto...fter a river in the ... The fourth, Ebola -Reston, has caused disease in nonhuman primates, but not ... Ebola Virus. The virus comes from the Filovir...

Conjunctiva

...ivided into the bulbar ... sealing the Space Between the Conjunctiva and Tenon's Capsule with Fibrin Glue ... Notes on ophthalmology involving nonhuman animals ... Extension of conjunctiva over the cornea. Acquired Abnormalities. Conjunctivitis ... Bulbar conjunctiva ... CONJUNCTIVA ... con...
nonhuman in Biological News

Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus

Using multi-disciplinary analysis that included cognitive, neurophysiologic, virologic, and molecular techniques, the team found both a low-level viral infection in the brain and immune cells that had infiltrated the brain in order to protect against the virus. "As in the rest of the body, in th...

K-State researcher, collaborators study virulence of pandemic H1N1 virus

...ic purposes as controls to validate our testing systems." The researchers also studied the virulence of two strains of the pandemic H1N1 virus in a nonhuman primate model as a way to predict how the strains would affect humans. Comparing an isolate from California with one from Mexico, Richt and his collab...

Stem cell research: From molecular physiology to therapeutic applications

...rapy Center at Xuanwu Hospital. His current research interest focuses on the understanding of basic biological properties of stem cells and developing nonhuman primate models for stem cell-based therapy of degenerative diseases. He has developed a stem cell mediated expression system for treating Parkinson's ...

Common fish species has 'human' ability to learn

...hed in the academic journal Behavioral Ecology , show that the cognitive mechanisms underlying cumulative cultural evolution may be more prevalent in nonhuman animals than currently believed. The findings show that big brains, like those in humans, are not necessarily needed as a pre-requisite for cumulati...

Researchers shed light on trading behavior in animals -- and humans

...ehavior, Beran explained. "We need to continue these kinds of tests with nonhuman animals to properly place human behavior in context with nonhuman behavior, and to understand the evolutionary roots of human economic decisi...

Social support during breast-feeding helps humans have more children

...e other humans around to share the work burden. nonhuman primates, which have similar energy demands while ...ring requires a smaller increase in energy, giving nonhuman and human primates more options to meet that energ...strates the stark difference between the human and nonhuman primate lactation experience. "What is it that ...

Discovery could lead to a new animal model for hepatitis C

...cellular factors a total of four that are required for the virus to enter nonhuman cells. The hepatitis C virus exclusively targets human liver cells, sugg... allow uptake of the virus, genes that are not expressed in other human and nonhuman cells, explains Rice. In past years, three proteins CD81, CLDN1 and SR-BI ...

JCI online early table of contents: Jan. 19, 2009

...School of Medicine, Aurora, have found the offspring of both lean and obese nonhuman primate mothers chronically consuming a high-fat diet exhibited an increase... TITLE: Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates AUTHOR CONTACT: Kevin L. Grove Oregon Health and Science Univ...

Avian flu becoming more resistant to antiviral drugs, says University of Colorado study

...raduate Meredith Wilson, Farhat Habib of Kansas State University and Daniel Janies of Ohio State University. "As these adamantanes have gotten into nonhuman vectors like birds, the positive selection for resistance to avian flu is rising," said Hill. "If Tamiflu is ever used in the manner of adamantanes, w...

Apolipoprotein(a): A natural regulator of inflammation

...ing. In vivo investigation of Lp(a) function has been impeded by the lack of availability of small animal models. Lp(a) is expressed only in humans, nonhuman primates and the European hedgehog. In this study Hoover-Plow's group utilized mice with apo(a) in a plasminogen deficient or replete background to st...
nonhuman in Biological Technology

Development of a Multiplex Bead-Based Assay for Antibody Screening of a Nonhuman Primate Colony on the Bio-Plex System

LaRene Kuller, David Anderson, Dominic Andrada, and Richard Grant, National Primate Research Center, University of Washington, Seattle, WA 98195 USA Introduction We have been using four separate enzyme-linked immunosorbent assays (ELISAs) ...

Vical Reports Third Quarter 2008 Financial Results and Continued Progress in Product Development Programs

...onstrated significant immune responses in multiple animal models, including nonhuman primates. Vaxfectin(R) has also demonstrated a dose-sparing effect (the abi...ating long-term protection against measles challenge in juvenile and infant nonhuman primates with a Vaxfectin(R)-formulated DNA vaccine. Conference Call Vi...

Vaxfectin(R)-formulated Measles DNA Vaccine Could Address Unmet Need for Infants

...(Nasdaq: VICL ) today announced that results from nonhuman primate studies of a Vaxfectin(R)-formulated DNA v...tailed results from studies in juvenile and infant nonhuman primates demonstrating that the vaccine induced ra...ng an infant's first year. The juvenile and infant nonhuman primate studies provide encouragement that Vaxfect...

Researchers say scientific reporting needs more perspective, less hype

...rrounding scientific patents. Its going to take a long time. Tenneille Ludwig, a Ph.D., is leading the culture optimization program for human and nonhuman embryonic stem cells in the laboratory of University of Wisconsin-Madison stem cell researcher James Thomson. After describing some painstaking work b...

Amplification Efficiency of TaqMan Gene Expression Assays

... was diluted in a 100-fold dilution range to obtain a dilution series with known amounts of cDNA. A constant amount of cDNA reverse transcribed from a nonhuman transcript (not detected in the Stratagene RNA pool) was used as a control to measure fold change. This transcript was made by T7 transcription of a 2...

Combat RNase Contamination in the Lab

... href="http://www.ambion.com/catalog/CatNum.php?2694">SUPERaseIn RNase Inhibitor (patent pending) is a protein-based inhibitor of nonhuman origin that noncovalently binds and inhibits the most common and troublesome RNases including RNase A, B, C, 1 and T1. SUPERaseI...

Constructing Directional cDNA Libraries from Limited Amounts of RNA

... to a known human gene Class 2: Sequence has a significant match with a human protein Class 3: Sequence has a significant match to a nonhuman protein Class 4: Mitochondrial and vector sequence Class 5: Unknown genes. Sequence has no significant match in the public d...
nonhuman in Biological Products

SUPERaseIn from Ambion

Description:... SUPERaseIn RNase Inhibitor (patent pending) is a protein based inhibitor of nonhuman origin that noncovalently binds and inhibits the most common and troublesome RNases including RNase A, B, C, 1 and T1. SUPERaseIn can be used in any a...
Company:Ambion

QIAGEN RNase Inhibitor (7500 U) from QIAGEN

Description:... For potent inhibition of RNase A-type ribonucleases Product Description: QIAGEN RNase Inhibitor is a protein of nonhuman origin that binds noncovalently and inactivates a variety of ribonucleases (e.g., RNase A, B, and C). It does not interfere with RNase T1, T2, H, U1, ...
Company:QIAGEN

Breeding and Maintenance (Nonhuman Primates) from Alpha Genesis, Inc.

Description:... AGI provides both long and short-term enriched housing for nonhuman primates and other laboratory animals in both quarantine and non-quarantine settings on a per diem basis. Breeding services are also available utilizi...
Company:Alpha Genesis, Inc.
nonhuman in Biological Definition

Stem cell

...ic stem cells available for federally funded research are contaminated with nonhuman molecules from the culture medium used to grow the cells, for example, mouse cells and other animal cells. The nonhuman cell-surface sialic acid can compromise the potential uses of the embryonic...
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(Date:4/18/2014)... online in The Gerontologist reports ... associated with a decrease in anxiety about death and ... over their lives. In particular, listening to gospel music ... and an increase in sense of control. , These ... men, and individuals of both low- and high-socioeconomic status. ...
(Date:4/18/2014)... University psychologists have made a brain-related discovery that ... disorders. , This discovery opens up the possibility ... suppress a specific brain activity that the researchers ... The Journal of Neuroscience has just ... McDonald, an associate professor of psychology and his ...
(Date:4/17/2014)... in non-cancerous prostate tissue may have nearly twice the ... no inflammation, according to results of a new study ... Center. , The link between persistent inflammation and cancer ... cancer those with a Gleason score between 7 ... aggressive and rapidly growing prostate cancers. , "What we,ve ...
(Date:4/17/2014)... of Experimental Biology and Medicine a ... and Paul Kenis in the Institute of Genomic ... of Illinois Urbana-Champaign describe their recent work on ... variety of cell functions including energy metabolism, signaling, ... in regulating normal cellular behavior, redox status has ...
(Date:4/17/2014)... created a new technology for modifying human cells ... body and selectively target cancer and other sites ... monitor and modify human physiology is a promising ... technology enabled bioengineers to build such devices that ... a customized fashion. , "The project addressed a ...
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(Date:4/17/2014)... In the most densely forested and most densely ... centuries of human needs, values and practices. Disturbances associated ... for agriculture and development, have set the stage for ... Service study reports. , The report Five anthropogenic ... needs in the Northern United States was ...
(Date:4/17/2014)... development of stem cell therapies to cure a variety ... cell populations based on cell surface markers. Researchers from ... that is highly expressed in a type of stem ... describe in an article in BioResearch Open Access ... publishers. The article is available free on the ...
(Date:4/17/2014)... A credit-card-sized anthrax detection cartridge developed at Sandia ... makes testing safer, easier, faster and cheaper. , ... is commonly found in soils all over the world ... both humans and animals. The bacteria can survive in ... B. anthracis may occur through skin contact, inhalation ...
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