Scientists identify lab-made proteins that neutralize multiple strains of seasonal and pandemic flu
Scientists have identified a small family of lab-made proteins that neutralize a broad range of influenza A viruses, including the H5N1 avian virus, the 1918 pandemic influenza virus and seasonal H1N1 flu viruses. These human monoclonal antibodies, identical infection-fighting proteins derived fro...Yerkes researchers propose ambitious new strategies for AIDS vaccine research
...ion or disease progression. This has been demonstrated in two large-scale clinical trials aimed, respectively, at eliciting HIV specific-antibodies to neutralize the virus and stimulating the immune system's "killer T-cells" to target the virus. "To put it another way, a conventional vaccine strategy can be ...Genes key to staph disease severity, drug resistance found hitchhiking together
...e assumed." The research group is continuing its study of PSM-mec in S. epidermidis , where the toxin is more prevalent. Ultimately, being able to neutralize PSM-mec and other toxins that attack human defenses could lead to new treatments for S. aureus and S. epidermidis disease. ...Preventing toxic shock syndrome and other severe diseases
...ny affect on the toxins," explains McCormick. "By understanding how these toxins work, we can look at developing drug inhibitors that will target and neutralize the toxins." On the flip side, McCormick believes these toxins could be utilized to fight cancer. "We know these toxins cause potent activation of...Photos: Don't Let Them See You Sweat This Summer
...rmer weather. Knock out body odor: Excessive underarm sweating can contribute to odors as the sweat dries and activates bacteria on your skin. neutralize odors by sprinkling baking soda on affected clothing and on athletic gear after use. Avoid mid-day workouts: When the sun is at its peek, the ...Calcium Isn't the Secret to Healthy Bones, Says Natural Solutions Magazine
...ts bone health more effectively: Protein is composed of amino acids. When you eat high-protein foods (including dairy), your body must neutralize these acids in the bloodstream, and it draws from its own reservoir of alkaline material--the calcium compounds in bone--to do that. When too much cal...NIAID media availability: New strategy proposed for designing antibody-based HIV vaccine
... These studies demonstrate that, contrary to widespread belief, it is not uncommon for people infected with HIV to naturally make antibodies that can neutralize a variety of HIV strains. These antibodies do not protect people from the virus because they arise years after HIV infection is established. However, ...Cytokine PharmaSciences Initiates Phase I Study of Oral Anti-Inflammatory Agent, CPSI-2364
...to produce than biologics and can be given orally. Moreover, because it is not a protein, CPSI-2364 is not expected to generate antibodies that could neutralize its activity and result in loss of efficacy over time." CPSI-2364 is a chemically-modified form of the synthetic guanylhydrozone, semapimod....Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy
...re pleased to advance the first of our LPM compounds designed to target and neutralize chemokine-mediated inflammation into clinical trials. CCL2-LPM has shown a ...ovel fusion protein therapeutics designed to selectively and systematically neutralize disease-related leukocytes. Founded in 2008, the company raised $11 million...Kiwifruit: Antioxidant Power in Quantity and Quality
...d in the Journal of the American College of Nutrition. Antioxidants include vitamins and phytochemicals called flavonoids that may have the power to neutralize unstable molecules called free radicals, which may be linked to chronic disease and aging. Consumption and increased absorption of antioxidants may he...CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date
...s types 16 and 18 with a cervical cancer vaccine to date. Experts believe that neutralizing antibodies -- so-called because they have the ability to neutralize cancer-causing virus types and prevent them from infecting cells in the cervix -- are essential for cervical cancer protection. The World Health Organ...Popular Energy Drinks Cause Tooth Erosion
...r reviewed journal, the pH level of soft drinks isn't the only factor that causes dental erosion. A beverage's "buffering capacity," or the ability to neutralize acid, plays a significant role in the cause of dental erosion. The study examined the acidity levels of five popular beverages on the market. The ...Abbott's ABT-874 Shows Positive Results for Maintenance of Response in Phase II Psoriasis Study
...Abbott is also researching biologic treatments for cancer and Alzheimer's disease. ABT-874 is a fully human monoclonal antibody designed to target and neutralize interleukin-12 and interleukin-23, two proteins associated with inflammation in psoriasis and other autoimmune disorders. Abbott plans to begin Phase ...Pre-clinical Data on Recent Advances with HIV VLP Vaccine Presented at AIDS Vaccine 07 Conference
... Liu described that in preclinical studies, VLP vaccination after DNA priming induced HIV-1 neutralizing antibodies to tier 1 viruses that are easy to neutralize and to a select number of tier 2 viruses that are much harder to neutralize. The tier 2 viruses include HIV-1 subtype B viruses, which are common in E...Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy
Jerusalem, May 5, 2009 Researchers at the Hebrew University of Jerusalem have discovered a method to potentially eliminate the tumor-risk factor in utilizing human embryonic stem cells. Their work paves the way for further progress in the promising field of stem cell therapy. Human embryonic ...Adding high doses of sludge to neutralize soil acidity not advisable
This release is available in Spanish . Sludge obtained from water purification plants can be reused, as fertiliser for soils, for example or to reduce their acidity. The main aim of this University of the Basque Country (UPV/EHU) PhD research thesis was to study the effects of the applica...Bleach found to neutralize mold allergens
First-ever human studies show bleach solution reduces allergenic properties of moldResearchers at National Jewish Medical and Research Center have demonstrated that dilute bleach not only kills common household mold, but may also neutralize the mold allergens that cause most mold-related health com...Defensins neutralize anthrax toxin
Researchers at the University of Pennsylvania School of Medicine have identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein known to be expressed in a number of EBV-associated cancers. Their findings demonstrate a new mechanism by which EBV transforms human B c...First human gets new antibody aimed at hepatitis C virus
...MMS) today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody they developed that can neutralize the Hepatitis C virus (HCV). The first volunteer received the antibody known as MBL-HCV1 on July 28, 2009, and the study is now proceeding and wil...Penn-Wistar team gains insight into HIV vaccine failure
...d Ad5 neutralizing antibody (nAb) titers, the main immune gatekeeper in most vaccine strategies. Antibodies produced in response to previous infection neutralize viruses by binding to them and preventing their entry into host cells. They work in concert with other immune cells, including CD4 T-cells, which buil...Baylor researchers unravel mystery of DNA conformation
... functions such as DNA replication, transcription, repair and recombination. DNA is also accompanied by a cloud of counterions (charged particles that neutralize the genetic material's very negative charge) and, of course, the protein macromolecules that affect DNA activity. "Many models and experiments have...Novel antibody prevents infection by hepatitis C virus
...r coat, known as the glycoprotein. Once they found human antibodies that looked promising, they evaluated in vitro the ability of those antibodies to neutralize the virus and selected a lead candidate antibody for further characterization. Collaborative work with clinical researchers from the Department of Med...New study overturns orthodoxy on how macrophages kill bacteria
...mage DNA and other cellular components and cause cell death. Bacteria and animal cells contain special enzymes, called superoxide dismutases, which neutralize an important ROS, called superoxide. Macrophages have harnessed these lethal compounds, dumping large quantities of superoxide onto engulfed bacte...Caltech scientists show why anti-HIV antibodies are ineffective at blocking infection
...mply don't have a long enough reach to effectively neutralize the viruses they are meant to target. Their fin...nto an equally dramatic increase in its ability to neutralize a virus. Having antibodies with two arms is nature...ent parts and compared their abilities to bind and neutralize the virus. They found, as expected, that one-armed...Researcher working on destruction of chemical weapons
...e dark side of deadly chemical agents, and Texas A&M University chemist Dr. Frank Raushel is helping with the fight by developing an enzyme that might neutralize one such chemical agent, the organophosphates. Synthetic organophosphates started their journey as insecticides in the 1930s but soon made their way...Biotechnology Value Fund Delivers Letter to Board of Directors of Avigen, Inc.
...Nevertheless, our response was to offer a compromise proposal: modify the poison pill to allow anyone to acquire as much stock as they like, however, neutralize the voting power on all shares of Avigen stock above a specified threshold. We specifically offered to have any additional shares that we acquire to ...Interferon Antibody Bioassays Services from PBL InterferonSource
Description:...erferons are cytopathic effect inhibition assays, also known as CPE and antiviral assays. The neutralization assay measures the antibody's ability to neutralize the CPE activity of the cytokine. Sample types include; tissue culture supernatents; serum and delivery formulations. In these assays, one unit is de...