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naive in Medical News

New Survey Suggests That Consumers Are Naive to the Risk of Botox Parties and the Importance of FDA Approval for Cosmetic Injectables

Survey also reveals less than 5% trust magazines or advertising for treatment information NEW YORK, May 20 /PRNewswire-USNewswire/ -- The Physicians Coalition for Injectable Safety ( http://www.injectablesafety.org ) and the health and beauty community RealSelf.com ( http://www.realself.com ...

Anesthesia Can Make Patients Vomit After Cosmetic Surgery - World's Top Expert Says PK Anesthesia Is Better

...us, the tube that takes food from the mouth to the stomach. More commonly, PONV tears sutures or causes blood clots (hematomas). "I was very naive about eliminating PONV. Without generating profits for some patent-protected drug (i.e. a 'proprietary' as opposed to a generic one) as part of the PO...

ALIMTA(R) (pemetrexed for injection) Receives Positive Opinion From CHMP as Maintenance Therapy for Nonsquamous Non-Small Cell Lung Cancer

...metastatic nonsquamous NSCLC after prior chemotherapy. Pemetrexed also is indicated, in combination with cisplatin, for the treatment of chemotherapy naive patients with unresectable malignant pleural mesothelioma. Globally, lung cancer is the most common form of cancer and the biggest killer, causin...

AGA Institute presents cutting-edge research during DDW

...e SONIC Study: A Randomized, Double-Blind Trial Comparing Infliximab and Infliximab plus Azathioprine to Azathioprine in Patients with Crohn's Disease naive to Immunomodulators and Biologic Therapy. W.J. Sandborn et al. (3:30 p.m.)* * This study is being highlighted during a DDW press conference on Tue...

Study Demonstrates Internet Risks for Teen Girls

... a manner that increases the risk for online sexual advances. Your behavior can change based on how you present yourself to the world. It isn't just naive kids who are vulnerable. Those who choose to present themselves as 'sexually sophisticated' are particularly vulnerable to those who would choose to b...

Light Sciences Oncology Announces Results of Study on Immunotherapeutic Mechanism of Aptocine(TM), a Novel Light-Activated Drug Therapy for Cancer

...the lymph node (LN) cells from treated and control mice were transferred to naive recipient mice. Recipients were challenged with a tumorigenic dose of 4T1 c... in their lungs. Aptocine acts as an in vivo vaccine--challenging a naive mouse with tumor 40 days after transferring immune cells from an Aptocine-t...

Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes

...ol and placebo groups had comparable A1C levels (8.2 and 8.1 percent, respectively). Results showed that patients on metformin-based therapy but naive to Welchol (i.e., those treated with placebo during the 26-week randomized phase), who were subsequently treated with Welchol for 52 weeks (n=41) duri...

Research Findings on Nine GlaxoSmithKline Cancer Compounds to be Presented at ASCO 2009

...mpound with a MET/VEGFR2 mechanism of action. ORAL PRESENTATION: "A randomized, double-blind Phase III study of pazopanib in treatment naive and cytokine-pretreated patients with advanced renal cell carcinoma (RCC)." Dr. C. Sternberg, San Camillo and Forlanini Hospitals, Italy; Presentation...

Process controlling T cell growth and production identified

..., who is the principal investigator of the current study. "What we discovered was that ELF4 activates an inhibitor that leads to cell arrest, stopping naive T cells from proliferation." A population of nave CD8 T-cell is always circulating in the body and maintained at a constant level. Memory T cells a...

50,000 Letters Sent to Notre Dame Alumni Re: Obama; In Letter, Bishop Gracida Urged Former U.S. Ambassador to the Vatican Mary Ann Glendon to Refuse Award

...be startled; the hypocrisy of the nation must be exposed; and its crimes against God and man must be proclaimed and denounced... ...But I am not naive ... there are many faculty and alumni who have bought into the confusion of the death movement. They place unity and peace above justice -- and there...
naive in Medical Technology

In Vitro and In Vivo Data Show Alfacell's Onocanse is Active Against Naive and Chemoresistant Neuroblastoma Cells

Pre-Clinical Results Demonstrate Potential of ONCONASE for Treatment of Neuroblastoma BLOOMFIELD, N.J., June 27, 2007 /PRNewswire-FirstCall/ -- Alfacell Corporation today announced that new data show ONCONASE, the company's lead drug candidate, is active against naive and chemoresistant neuroblast...

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

... the safety and efficacy of velaglucerase alfa in 25 patients with Type 1 Gaucher disease. Patients aged two years and older who were treatment naive were eligible to participate in the study if they presented with disease-related anemia and had at least one of the following clinical manifestations ...

New Results From ARTEN Study of Nevirapine Plus Tenofovir and Emtricitabine (TDF/FTC) Versus Boosted Protease Inhibitor Regimen of Atazanavir/Ritonavir Plus TDF/FTC Revealed

...gelheim Pharmaceuticals, Inc. "The study also provides additional important data on the effect of VIRAMUNE on patient lipid profiles in antiretroviral naive patients." Efficacy Data Of the patients who received nevirapine in the study (n=376), 67 percent achieved the study's primary end...

Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV

...cidosis, bone marrow suppression, fat atrophy and, with certain agents, increased risk of myocardial infarction.(5-7) About the Phase II naive Study This randomized, controlled, open-label study is projected to enroll approximately 200 treatment-naive HIV-infected adult patients at m...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

... This trial will consist of a six-month double-blind, randomized, placebo-controlled treatment stage and will enroll approximately 60 subjects who are naive to enzyme replacement therapy (ERT) or who have not received ERT for at least six months prior to the start of treatment with Amigal. The Amigal trea...

New Study Showed Lantus(R) Plus One, Two or Three Shots of Apidra(R) Lowered Patients' Blood Sugar

...tific Sessions of the American Diabetes Association (ADA). The study was a multicenter, randomized, open-label, parallel group study in insulin naive patients. Lantus(R) was started for a 14-week run-in period, after which time patients not at goal (A1C<7%) at week 0 were randomized to a 24-week...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

...ely to Maintain Steroid-Free Remission in Patients naive to Immunomodulators and BiologicTherapy CHIC...inadequate response to conventional therapies, but naive to immunomodulators and biologic therapy, were pre...rately to severely active Crohn's disease who were naive to immunomodulator and biologic therapy. A total ...

Medivation Announces Positive New Efficacy Data From Phase 1-2 Trial of MDV3100 in Advanced Prostate Cancer Patients

... (50% or more stable (stable favorable from baseline) disease) disease) status) Chemotherapy- naive 62 percent 80 percent 63 percent 75 percent Post-chemotherapy 51 percent 65 percent 51 percent 37 percent ...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...ann JF, de Bruijne J, et al. Safety and Antiviral Activity of SCH 900518 Administered as Monotherapy and in Combination with Peginterferon Alfa-2b to naive and Treatment-Experienced HCV Infected Patients. 44th European Association for the Study of the Liver (EASL) 2009 Annual Meeting; April 22-26, Copenh...

Amicus Therapeutics Announces Issuance of New Plicera(TM) Composition of Matter Patent

...pment programs and our pharmacological chaperone technology platform." Plicera is currently being studied in an ongoing Phase 2 study in patients naive to enzyme replacement therapy. This six-month study is designed to evaluate safety and to demonstrate trends of efficacy, as measured by the standard...
naive in Biological News

New simulation shows consequences of a world without Earth's natural sunscreen

...rgest recorded Antarctic ozone hole was recorded in 2006. "I didn't think that the Montreal Protocol would work as well as it has, but I was pretty naive about the politics," Stolarski added. "The Montreal Protocol is a remarkable international agreement that should be studied by those involved with glo...

New culture method for hepatitis C virus uses primary hepatocytes and patient serum

...ion of core protein (for virus particle formation). Release of infectious virus particles was confirmed, as media from these cells were able to infect naive hepatocytes. Finally, virus particles were examined by electron microscopy and shown to possess the expected size and shape of HCV virus particles. ...

Flu shot effective against drifted influenza, nasal spray vaccine less so

...sal spray is very effective in children and may be more effective than the killed vaccine in the young. "FluMist works very well in children with naive immune systems," Ohmit said. The FDA approval of FluMist limits its use to people between age 5 and 49 years. In another paper in the same edition...

Polynesia explorers created worldwide web of scientific knowledge

...ntered negatives: "ferocious island politics, exploitative native elites and disruptive consequences of their own visits that called into question the naive assumption of fraternity with native peoples," Liebersohn wrote. Despite everything, these three travelers became "influential and insightful ethnogra...

Ancient DNA helps UF researchers unearth potential hemophilia therapy

...t UF researchers bypassed this immune response by performing gene therapy on mice within 24 hours of their birth, when their immune systems were still naive and would accept the protein. This type of approach cannot be used in human babies yet because doctors have no way of gauging how severe hemophilia...

New technology shows our ancestors ate…everything!

...ent of the surface's appearance and is described in the August 4 issue of Nature. "Paleontologists and physical anthropologists have had a somewhat naive view on diet, in part due to the limitations of time-consuming, subjective approaches to analyzing teeth," said Teaford. "So it's a huge step to have ...
naive in Biological Technology

Pharmasset and Roche Obtain FDA Consent to Start a Phase 2b Study With R7128 in Treatment Naive HCV Patients

PRINCETON, N.J., Jan. 12 /PRNewswire-FirstCall/ -- Pharmasset, Inc. (Nasdaq: VRUS ) announced today that they and their development partner, Roche, have agreed with the FDA on the final design for a phase 2b trial with R7128, a nucleoside inhibitor of hepatitis C (HCV), slated to initiate in the...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results

... The trial will consist of a six-month double-blind, randomized, placebo-controlled treatment stage and will enroll approximately 60 subjects who are naive to enzyme replacement therapy (ERT) or who have not received ERT for at least six months prior to the start of treatment with Amigal. The Amigal trea...

Anadys Pharmaceuticals Receives FDA Clearance of Phase II Protocol to Study ANA598 in Combination With Interferon-Alpha and Ribavirin in HCV Patients

...ed to commence within the next several weeks. In the Phase II study, naive genotype 1 patients will receive ANA598 or placebo in combination with Pega...potent antiviral activity and good tolerability. In a monotherapy study in naive genotype 1 patients, treatment with ANA598 for three days led to median dec...

Anadys Pharmaceuticals Reports Second Quarter 2009 Financial Results and Program Highlights

...hase II study of ANA598 in combination with pegylated interferon-alpha and ribavirin for the treatment of chronic hepatitis C. In the Phase II study, naive genotype 1 patients will receive ANA598 or placebo in combination with Pegasys(R) (peginterferon alfa-2a) and Copegus(R) (ribavirin, USP) (a current s...

Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures

...ed liver disease who have anti-HCV serum antibodies and /or the presence of HCV RNA. INFERGEN is currently FDA approved for TIW monotherapy dosing in naive and previous treatment failure patients. Important Safety Information Physicians and patients can obtain additional prescribing information ...

New Survey Reveals That More Than Half of Rheumatoid Arthritis Patients in Europe and Canada Feel Their Disease Controls Their Lives

...s - The surveyed patients were either on biologic therapy or were biologic naive but eligible for biologic treatment based on a broad set of criteria. Of t...ugh December 2008. A total of 586 patients, approximately 30 biologic naive and 35 currently using anti-TNF alpha agents from nine countries (Canada, F...

Anadys Pharmaceuticals, Inc. Announces Strategic Restructuring to Focus Operations on Continuing the Advancement of ANA598

...ceed, Anadys intends to initiate the trial during the third quarter of 2009. The current protocol design calls for 12 weeks of dosing ANA598 in naive genotype 1 patients in combination with SOC, compared to a control arm that will receive a placebo and SOC. After 12 weeks, patients are expected to ...

Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

... that pixantrone could extend our ability to use a highly active anthracycline-like drug in such patients and deserves to be examined in anthracycline naive patients as a potential alternative to currently available standard anthracycline drugs." The PIX 301 EXTEND ( E xpanding the reach of antrhacy...

Valeant Pharmaceuticals Reports Encouraging Final Results With Taribavirin Phase IIb Study

...drug of ribavirin which is in development for the treatment of chronic hepatitis C in conjunction with a pegylated interferon. The study in treatment naive genotype 1 infected subjects was of standard design, consisting of 48 weeks of treatment with a 24-week follow-up period. It explored three weight-ba...

ChemDiv Group Acquires Prudentas Through ChemRar High Tech Center

...: "Our decision to make this investment capitalizes on the growing trend of conducting clinical trials in Eastern Europe; based on the availability of naive patient populations, rapid and efficient trial recruitment and high data quality across a broad range of therapeutic indications including CNS, cardio...
naive in Biological Dictionary

T lymphocytes

...n their surface which are ... Although the requirements for T lymphocyte homing to lymph nodes (LNs) are well ... and arrest coefficients than naive T lymphocytes in the deep paracortex. ... T lymphocytes play a major role in defense against intracellular pathogens such ... " T " lympho...

T cell

...wn T cell mediated immunity towards the end of an ... Immunobiology is intended as an introductory text for use in immunology courses for ... naive T cells require a co-stimulatory signal from professional antigen ... T cell summary with 17 pages of encyclopedia entries, essays, summa...

B lymphocytes

... have potent phagocytic and microbicidal abilities" ... As a measure of B lymphocyte repertoire diversity, we have analysed size ... (CDR3) in naive and memory B lymphocytes isolated from patients before HSCT and ... In contrast, intravascular B lymphocytes have a much lower expressio...
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