IMF Launches World’s First DNA Database for Myeloma Patients
A biologist at Washington University in St. Louis has shown that for some fish species, females prefer males with larger sexual organs, and actually choose them for mating. That does not exclude males with an average-sized sex organ, called a gonopodium. These fish out-compete the larger-endowed males in a predator-laden environment because they have a faster burst speed than the males with large...Compound from marine bacteria shows potential as multiple myeloma therapy
An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell. The experimental compound, NPI-0052, has been found to block or inhibit c...Genome changes tracked during multiple myeloma initiation, progression and treatment
Scientists have made significant progress toward elucidating key genetic events associated with the development and progression of multiple myeloma (MM), an incurable malignancy that is the second most common cancer of the blood. The results, published in the April issue of Cancer Cell, provide new genetic and biological insights that open innovative directions for the discovery of effective ther...An advanced genetic diagnostic method for multiple myeloma
A researcher at the University of Navarra, Borja Sáez Ochoa, has proposed a new genetic diagnostic method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages. The dissertation of this biologist, produced in the Department of Genetics of the School of Sciences of the University of Navarra, and in the Institute of Human Genet...Investigating the measles virus as a tool to kill multiple myeloma
Mayo Clinic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow that currently has no cure. This is the third of a series of molecular medicine studies in patients testing the potential of measles to kill cancer. “This is the beginning of a long but exciting process,?says Angela Dispenzieri, M.D.,...Associated therapy for multiple myeloma
According to a new study it is observed that thalidomide is effective as first-line therapy for newly diagnosed multiple myeloma patients when combined with a standard chemotherapy agent. Researchers from the Mayo Clinic in Rochester, Minn.// gave 60 newly diagnosed myeloma patients the drug thalidomide along with the synthetic steroid dexamethasone. Results show 55 percent of patients responded...Latest drug shows promise in multiple myeloma
According to researchers, many trials show that a new type of drug can assist patients with multiple myeloma who have failed to respond to other treatments.// Multiple myeloma is an incurable cancer of the bone marrow. Researchers at Dana-Farber Cancer Institute have been assessing a new drug, called bortezomib, in a group of 180 patients who had not been helped by other forms of treatment. In th...Bortezomib for salvage therapy against progressive myeloma
Despite the initial efficacy of these therapies against multiple myeloma (MM), relapse is invariably the rule. Bortezomib (Velcade, formerly PS-341, Millennium, USA) is a novel first-class agent that inhibits the proteasome, a // multicatalytic cellular enzyme whose activity entails several molecular mechanisms, including, in particular, the NF-kB pathway. Currently, bortezomib, alon...Plasma Exchange Of No Use In Multiple Myeloma
New findings published in the Annals of Internal Medicine this week have found that the standard therapy for patients who are on the verge of kidney failure is useless. //The study conducted by researchers at Lawson Health Research Institute scientists in London, Canada found that a treatment called "plasma exchange" in patients with multiple myeloma has no benefits. This means that the...Lenalidomide, Granted Approval by FDA to Join Multiple Myeloma Drugs
Graham Burton, M.D., SVP, Regulatory Affairs and Pharmacovigilance said that FDA’s approval of REVLIMID (lenalidomide) offered a new oral drug option// to the group of people suffering from multiple myeloma. Celgene Corporation (Nasdaq: CELG) announced that the U.S. Food and Drug Administration (FDA) has granted approval for its Supplemental New Drug Application (sNDA) for an additional...Chromosome Analysis, Multiple Myeloma Panel by FISH
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Multiple Myeloma Panel by FISH
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...