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mutate in Medical News

Virus Can Mutate lethally With Help Of Carbohydrates

Study finds that viruses too look out for carbohydrate molecules so as to prepare for an invasion onto our cells.// A new study by the University of Florida, which has been published in the current Journal of Biological Chemistry, states that it not only humans but viruses too that crave for ...

WHO Warns That Bird Flu Virus Could Mutate Anytime

The World Health Organisation (WHO) has said that the risk of the H5N1 virus undergoing a lethal mutation is still high. In a report analyzing 205 infections that occurred from December 2003 and April 2006. // Since the human infections have peaked in winter and spring months, the WHO also war...

Tips from the journals of the American Society for Microbiology

...an-to-human transmission has remained limited, the fatality rate among those reported human cases is greater than 60%. The threat that the virus will mutate and achieve efficient human-to-human spread emphasizes the need for effective preventative therapies. Vaccination is considered the optimal method ...

Eliminating polio requires global, coordinated effort -- Health Affairs article highlights risks, rewards of eradication

...ng use and eventual termination of the oral polio vaccination among countries because weakened live virus strains in the oral vaccine can occasionally mutate and circulate as vaccine-derived poliovirus; Securing stocks of wild poliovirus stored in laboratories all over the world; Promoting effective...

Swine Flu Summit Focuses on Preparedness

...instance -- and 120 other countries, especially in the Southern Hemisphere where the flu season is under way. Scientists are concerned the virus could mutate as it travels around the world, becoming more virulent and posing a greater health threat. What makes the H1N1 strain different from the typical se...

U.S. Considers Massive Swine Flu Vaccination Program

...s it migrates from the Northern Hemisphere to the Southern Hemisphere, where the flu season is now under way. Scientists are concerned the virus could mutate as it circulates around the world, becoming more virulent and posing a greater health threat. "The virus is not mutating for the moment, it is stab...

1 Million Americans Likely Stricken by Swine Flu: CDC

...s it migrates from the Northern Hemisphere to the Southern Hemisphere, where the flu season is now under way. Scientists are concerned the virus could mutate as it circulates around the world, becoming more virulent and posing a greater health threat. "The virus is not mutating for the moment, it is stab...

Swine Flu Continues to Flare Up, CDC Says

...ne flu doesn't yet seem any more lethal than the regular flu that each winter kills 36,000 people in the United States alone, scientists fear it could mutate as it circulates around the world, becoming more virulent and posing a greater health threat. Nearly 40,000 people in 76 countries have been infect...

New Swine Flu Strain Found in Brazil: Report

...ne flu doesn't yet seem any more lethal than the regular flu that each winter kills 36,000 people in the United States alone, scientists fear it could mutate as it circulates around the globe, becoming more virulent and posing a greater health threat. Nearly 36,000 people in 76 countries have been infect...

No Time for Complacency in Pandemic Planning: Aon

...tion does not indicate a change in the severity of the current outbreak. That said, influenza viruses are notoriously unpredictable and this virus may mutate to become more severe at any time. Pandemics typically manifest in three or more waves of disease which may differ in severity and can occur at any ti...

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mutate in Medical Technology

Glivec(R) is the First Adjuvant Treatment Approved in the UK to Delay Return of Gastrointestinal Cancer After Surgery

...ions.(11) KIT is a protein in the body that plays an important role in the growth and survival of GIST.(12) In patients with GIST, the KIT protein can mutate and become over active.(5) The normal role of KIT is to provide the 'signal' to cells in the body to grow and divide: this signal is not given ...

Arrayit to Mass Produce Rapid H1N1 Swine Flu Test Chip

...oring the progression of the pandemic, and selecting vaccine strains. Scientists around the world are concerned that the influenza virus could one day mutate and acquire the properties needed to quickly spread between people, resulting in a pandemic." Arrayit's unique microarray platform allows the des...

Muscadine Grape Skin Dietary Supplement Protects against Cancer Therapy Radiation Side Effects

...s. Some cancer patients that undergo radiation treatment unfortunately develop leukemia. This occurs when normal stem cell found in bone marrow mutate and grow into tumors, causing leukemia's or blood cell cancers. A safe and natural way to protect patients is needed and this may be through the use ...

Preventing Prostate Cancer and BPH: Prostate-Health Expert Available (National Men's Health Week Is June 9-15)

...ked to prostate cancer in several occupational-health studies. This known human carcinogen inhibits DNA repair, which allows cancer cells to mutate and multiply. -- African-American men are known to have a higher risk of prostate cancer than white men. Kristal and colleagues also foun...

Abbott's m2000(TM) Molecular Diagnostic Instrument and RealTime HIV-1 Test Win Chicago Innovation Award

...nce the first diagnostic tests for the HIV virus came on the market in 1985, public health authorities have been concerned about the virus' ability to mutate and create new strains of subtypes that may elude detection. Optimal treatment of HIV depends on accurate measurement of viral levels, but if variant ...

Novavax Pandemic Flu Vaccine Provided Protection Against a Lethal Challenge of Live Virus, Pre-Clinical Data Show

...Bright said. "The goal of prevention in a pandemic setting is to be prepared with a vaccine that can protect against varying strains of the virus that mutate as they travel around the globe, and to have enough supply to protect vulnerable populations. We believe our VLP vaccine may provide a unique solution...

New Flu Vaccine From PepTcell Could Provide Immunity Against All Strains of Influenza Virus

...ective against all strains of flu virus, including pandemic strains. Current flu vaccines only work against specific virus strains. As these strains mutate frequently, vaccines also need to be updated. As such they do not provide protection against emerging flu strains, such as seasonal or avian flu. Usin...

New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus

...ective against all strains of flu virus, including pandemic strains. Current flu vaccines only work against specific virus strains. As these strains mutate frequently, vaccines also need to be updated. As such they do not provide protection against emerging flu strains, such as seasonal or avian flu. Usin...

BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine

...us. Farmers and poultry producers already have suffered losses in the billions of dollars. There is widespread concern that a strain of avian flu will mutate into a new form that is contagious among humans. Since there is currently no truly effective vaccine available to protect humans from H5N1 and humans ...
mutate in Biological News

Forced evolution: Can we mutate viruses to death?

HOUSTON -- Nov. 10, 2008 -- It sounds like a science fiction movie: A killer contagion threatens the Earth, but scientists save the day with a designer drug that forces the virus to mutate itself out of existence. The killer disease? Still a fiction. The drug? It could become a reality thanks to a...

Darwin in a test tube

...sly evolve in the test tube. The basis of this evolution comes from the fact that each time one of the molecules replicates, there is a chance it will mutate typically about once per round of replication so the population can acquire new traits over time. Two years ago, Voytek managed to develop a seco...

Avian flu research sheds light on swine flu outbreak

...influenza transmission) with the virus he created, and allowed the virus to mutate in the species. Before long, healthy ferrets that shared air space but not...and when they occur in nature, or even which strain of avian influenza will mutate to infect mammals. "This is just the tip of the iceberg," said Perez. "...

CSHL-led team identifies key decision-point at which cells with broken DNA repair themselves or die

...to signals from such resident sensors when they are triggered by exposure to radiation or other toxic processes, which if unchecked can cause genes to mutate and cancerous tumors to begin forming. A team of biologists led by Professor Nicholas Tonks, Ph.D., F.R.S., of Cold Spring Harbor Laboratory (CSH...

A natural approach for HIV vaccine

...o is a Howard Hughes Medical Institute investigator. "This should make people think about what an effective vaccine should look like." HIV strains mutate rapidly, making them especially wily adversaries of the immune system. But one element is shared almost universally among the diverging strains a pro...

Scripps research team identifies key molecules that inhibit viral production

...eeded. But one of the critical problems in developing drugs for HCV is that it mutates at such prodigious rates. An RNA virus like hepatitis C can mutate at a rate estimated as high as one million times that of DNA viruses; in contrast, DNA viruses contain an enzyme (polymerase) that acts as something o...

Relationships in rank and file

... between amino acids is measured by how often they mutate into each other without adverse effects, a measure... much more about how likely two amino acids are to mutate into each other", explains Soeding, who heads the ...n, the amino acid valine, for example, can usually mutate into any of the other 19 amino acids without any a...

Researchers recreate SARS virus, open door for potential defenses against future strains

...r vaccines and treatments that would be effective against any strain of SARS that might infect humans in the future. Viruses that start in animals and mutate to infect humans tend to be slightly different each year. An example is the influenza virus, which is different each year and requires a different vac...

New type of vaccines deliver stronger and faster immune response

... animals. The scientists also believe that the new technology will be effective despite the ability of different viruses and bacteria to constantly mutate and develop resistance. Key benefits of the new technology: The new platform delivers a broad and very powerful immune re-sponse, enabling t...

Washington University scientists first to sequence genome of cancer patient

...gests that there is a tremendous amount of genetic diversity in cancer, even in this one disease," Wilson says. "There are probably many, many ways to mutate a small number of genes to get the same result, and we're only looking at the tip of the iceberg in terms of identifying the combinations of genetic m...
mutate in Biological Technology

CEL-SCI Corporation Releases Letter to Shareholders

...level meeting in Cancun, Mexico. At this meeting the WHO's Director General was underscoring the unstoppable nature of swine flu and its potential to mutate - "Constant, random mutation is the survival mechanism of the microbial world. Like all influenza viruses, H1N1 has the advantage of surprise on its s...

ImmunoVaccine Technologies Partners with FIT Biotech to advance a therapeutic HIV vaccine

...ndidate," commented Dr. Marc Mansour, Vice President R&D at IVT. The development of an HIV vaccine is complicated by the ability of the virus to mutate rapidly. FIT Biotech has addressed this challenge by designing a synthetic DNA plasmid, known as GTU(R) MultiHIV that covers the antigenic variability...

Bioinformatics A New Science

... computer program that could search for patterns in DNA and quickly return results. Then Michele would verify the results in lab tests where she would mutate genes to discover their true functions. Bioinformatics is attracting hundreds of researchers from computer science and biology because it takes ver...

WARF Granted New Antibiotics Patent

... patent. There has only been one new class of antibiotics approved for use in the last 40 years. This is also a very good target because bacteria must mutate in many places to evade a compound that interferes with this binding, thus reducing the chances that a bacteria will become resistant to an antibiotic...

Studies Offer New Insight into HIV Vaccine Development

...n group has been studying immunity to AIDS viruses since the early 1990s. Most recently, the researchers have been studying the ways in which viruses mutate to "escape" recognition by the body's killer cells. Killer cells are white blood cells that perform immune "surveillance" throughout the body, detecti...

Flu institute a booster shot for Wisconsin biotech stature

...ance on the drug, which is being stockpiled around the globe, has been called into question. One of the challenges with influenza-A viruses is they mutate as they go through different organisms, either of the same species or when they jump species, which increases the degree of difficulty of making new f...

Technology played key role in E. coli alerts

...e genetic information available to other states, a point Gov. Jim Doyle emphasized in his statement on the outbreak. "In the E. coli case, the bugs mutate constantly," Foldy said. "But if you're seeing the same genetic pattern appearing around the country, you can use this evidence to link the cases to a...

TKB1 Cells Identify Receptor Tyrosine Kinase Interacting Proteins

...tion sites can be identified which, when mutated in vivo, lead to a loss of protein activity or stability. For example, when two tyrosine residues mutate within the juxtamembrane region of the platelet-derived growth factor receptor, the kinase is rendered catalytically inactive; 9 hence, interacti...

Randomize Gene Sequences with New PCR Mutagenesis Kit

...are represented. Taq is approximately three times more likely to mutate As and Ts than Gs and Cs (ATGC/GCAT ratio >1 2,3 ), while Mutazyme DNA polymerase is nearly three times more likely to mutate Gs and Cs (ATGC/GCAT ratio 0.2). Both enzymes prefer to incorpor...
mutate in Biological Products

TargeTron Gene Knockout System from Sigma-Aldrich

Description:...to the well-validated TargeTron algorithm on the Sigma website (www.sigma-aldrich.com/targetronaccess), using one or more of the output primer sets to mutate the TargeTron intron template via PCR, ligation of the fragment into the pACD4K-C linear vector, transformation of the host, induction of gene disrupt...
Company:Sigma-Aldrich
mutate in Biological Definition

Antigenic shift

...rds, giving influenza A the opportunity for a major reorganization of surface antigens. Influenza B and C only infect humans, minimizing the chance to mutate drastically. Flu strains are named after their types of hemagglutinin and neuraminidase surface proteins , so they will be called, for example, ...

Avian influenza

...health experts are concerned that a virus that mutates to the point where it can cross the species barrier (i.e. from birds to humans) will inevitably mutate to the point where it can be transmitted from human to human. It is at that point that a pandemic becomes likely. The first cases of avian influenz...

DNA

...ingle-stranded form. Because many of the DNA repair mechanisms of cells work only on paired bases, viruses that carry single-stranded DNA genomes mutate more frequently than they would otherwise. As a result, such species may adapt more rapidly to avoid extinction. The result would not be so favorable...

Gene duplication

...ons will lead to the death of the organism. When a gene is duplicated selection may be removed from one copy and now the other gene locus is free to mutate and discover new functions. Alternatively, the gene may acquire deleterious mutations and become a pseudogene . The postulate that gene duplicatio...

Life

...r that fire is not alive, because fire releases all the oxidative energy of its fuel as heat. Viruses reproduce, flames grow, some software programs mutate and evolve, future software programs will probably evince (even high-order) behavior, machines move, and proto-life, consisting of metabolizing cells ...

Molecular biology

...sequence to be copied (millions of times), or altered in predetermined ways. For example, PCR can be used to introduce restriction enzyme sites, or to mutate (change) particular bases of DNA. PCR can also be used to determine whether a particular DNA fragment is found in a cDNA library . Gel electro...
mutate in Biological Dictionary

Prostate gland

... cancer is a disease in which cancer develops in the prostate , a gland in the male reproductive system. It occurs when cells of the prostate mutate and begin to multiply uncontrollably. These cells may metastasize... Learn about prostate cancer treatment, causes, signs, stages, hormone ...

Mutation

...ation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence of the ... mutate a DNA sequence! ... A mutation is any spontaneous heritable change in DNA sequence that contributes ... A neutral mutation either results in...

DNA damage

...heory of aging proposes that aging is a consequence of unrepaired DNA damage accumulation. Damage in this context includes chemical reactions that mutate DNA and/or interfere with DNA replication. Although both mitochondrial and nuclear DNA damage can... Science and technology news stories tagg...

Back Mutation

...mosomes. ... Looks at changes in the information stored in the genetic material, how they occur, and what the consequences of such ... base could mutate back to its original ... ...
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