Man and mouse share genome structures
In the most detailed large-scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off. Their findings may help scientists understand regulatory mechanisms underlying cancer and human development. The research team includes first author Bradley Bernstein, recipient of a Howard Hughes Medical Institute (HHMI) physician postd...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characteristic brain plaques are removed.Researchers at Washington University School of Medicine in St. Louisinjected mice with an antibody for a key component of brain plaques,the amyloid beta (Abeta) peptide. In areas of the brain whereantibodies cleared plaque...Genome-wide mouse study yields link to human leukemia
Thanks to a handful of very special mice, scientists have discovered a new tumor suppressor gene and a unique chemical signature implicated in the development of human leukemia, findings that open up a "treasure box" of opportunity and possibility, study authors say. Researchers in The Ohio State University Comprehensive Cancer Center bred a type of mouse that develops acute lymphoblastic...Mouse brain tumors mimic those in human genetic disorder
A recently developed mouse model of braintumors common in the genetic disorder neurofibromatosis 1 (NF1)successfully mimics the human condition and provides unique insightinto tumor development, diagnosis and treatment, according toresearchers at Washington University School of Medicine in St. Louis.After validating their animal model, the team made two importantdiscoveries: New blood vesse...Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
Gastric and colorectal cancers account for more than 1 million deaths worldwide every year and several research groups have been working to identify the molecular events that result in the initiation and progression of these tumors. It has been established that interfering with the function of one gene, called Adenomatous Polyposis Coli (APC) has a profound effect on the cells lining the innermos...Mouse Anti-Amodiaquine Monoclonal Antibody, Unconjugated, Clone 6D10 from AntibodyShop A/S
Description:Amodiaquine...Mouse Anti-Protein S Monoclonal Antibody, Unconjugated, Clone HYB 232-02 from Abcam
Description:Mouse monoclonal [HYB 232-02] to Protein S ( SwissProtID: P07225...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Mouse Testis from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes
Stratagene Cloning Systems from the cDNAsequences of mismatch repair genes. These genes code for specialized proteinsthat participate in correcting areas of base mispairing in DNA. We have...Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
Weiping Yang Matt C. Petre Darrel Holmes Peter L.Pingerelli Stratagene Cloning Systems, Inc. Stratagenes IsoDetect mouse monoclonal antibody isotyping kit is asimple, rapid and sensitive method for identifying mouse monoclonal antibodyisotypes in a single step. Each IsoDetect test card...Mouse Tail Genomic DNA Isolation Protocol(1)
Note: Genomic DNA is fragile. High molecular weight DNA is sheared easily by mechanical forces. Use suitable large-bore pipet tips or equipment when pipetting genomic DNA. Do not vortex solutions containing genomic DNA. Place a 1 cm tail sample into a 1.5 ml microcentrifuge tube; this may be stored...Mouse Tail Genomic DNA Isolation Protocol(1)
Note: Genomic DNA is fragile. High molecular weight DNA is sheared easily by mechanical forces. Use suitable large-bore pipet tips or equipment when pipetting genomic DNA. Do not vortex solutions containing genomic DNA. Place a 1 cm tail sample into a 1.5 ml microcentrifuge tube; this may be stored...Mouse Allergen Found In Homes Could Trigger Asthma In Kids
The amount of mouse allergen found in the air in many inner-city homes could be significant enough to trigger asthma symptoms // in children say researchers. According to researchers children living in inner-city homes are continuously exposed to the allergy-causing substance found in mouse urine that is circulating in the air and exposure increases their risk for developing allergic sen...Researchers Develop Mouse Model Of Brain Tumor
A team of researchers, led by Dr. Martine Roussel of the St. Jude Children’s Research Hospital has developed a mouse model of medulloblastoma, the most common malignant brain tumor found in children. // Basically, medulloblastomas are malignant tumors that are formed by cells which are not yet mature or in other words by poorly developed brain cells. These tumors are usually formed in...German Scientists Create Stem Cells From Mouse Testes
German Scientists claim to have transformed testicular cells obtained from male mice into embryonic stem cells//, biological building blocks that have the remarkable ability to transform into other cell types. This research led to the belief the same could be achieved in humans, helping settle down the controversy associated with the derivation of embryonic stem cells from unused em...Mouse Models To Determine The Cause Of Aggressive Leukemia
According to the research conducted by the scientists at St. Jude Children’s Research Hospital it was found that mutation and loss of tumor suppressor gene resulted in aggressive leukemias.// Researchers have used mouse models to determine the reason behind aggressive nature and drug resistant nature of the acute lymphoblastic leukemia (ALL). The investigators found that the combination of a mut...Mouse Model Beneficial to Study of Head and Neck Cancer
The development of a mouse model by the Oregon Health & Science University Cancer Institute research laboratory has proved beneficial in the study of the often devastating// head and neck squamous cell cancers. The research was conducted by Xiao-Jing Wang, M.D., Ph.D., and his colleagues. The results of their research breakthrough have been published in the May 15 issue of Genes & Devel...Antigen-Antibody Pen For Mouse Primary antibodies
Description:Advantages of using the Antigen-Antibody Pens-Using a proprietary and patented technology, ADI has designed and developed specialized fountain pens, called Antigen-Antibody pens-TM, that will allow researchers to deliver or write/mark the blotting membranes in any form or shape or size. A specially formulated antigen-bonded colored dyes helps to see antigen being written on the membrane. One can...Human Anti-Mouse Antibody (HAMA), ELISA
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Allergen, Epidermals & Animal Proteins, Mouse Epithelium
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Allergen, Epidermals & Animal Proteins, Mouse Urine
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Targanta Study Shows Oritavancin Treatment Effective in a Mouse Model of Anthrax
Single-Dose Protection Observed Prior to or Up to 24 Hours AfterExposure to Anthrax TORONTO, Ontario, May 24, 2007 /PRNewswire/ -- TargantaTherapeutics Corporation announced today the results from a recentstudy demonstrating oritavancin as a potential therapy for treatingexposure to Bacillus anthracis, the bacterium which causes anthrax,an acute infectious disease. Oritavancin, a novel se...