First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
Chicken-produced antibodies demonstrate enhanced cell killing compared to conventionally produced anti-cancer antibodies Origen Therapeutics today announced the first published scientific report of fully functional, human sequence monoclonal antibodies (mAbs) produced in chickens. The antibodies were expressed solely in the chicken oviduct and deposited into egg white in concentrations of...Report calls for improved monoclonal antibodies against solid tumors
A new report by leading experts in monoclonal antibody research for oncology offers a conceptual framework for future research in the design of antibody therapies against solid tumors. Writing in the January 15, 2007 issue of CANCER ( ), a peer-reviewed journal of the American Cancer So...Recombination protein dynamics observed with single monomer resolution
Using a sensitive, single-molecule measurement technique, researchers at the University of Illinois at Urbana-Champaign have observed the life cycle of RecA, a protein that plays a major role in repairing damaged DNA. RecA is a DN...Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
Effector T cells (Teff cells) are involved in activating and directing other immune cells, while regulatory T cells (Tregs) act to curb the over-aggressive responses of the T cell population. Researchers continue to work on devising ways to mobilize anti-tumor Teff cells in order to better shape the immune response to tumors. Previously, James Allison and colleagues from Memorial Sloan-Ket...Therapeutic role found for carbon monoxide
In a medical case of Jekyll and Hyde, carbon monoxide ?the highly toxic gas emitted from auto exhausts and faulty heating systems ?has proven effective in treating the symptoms of pulmonary arterial hypertension (PAH), an extremely debilitating condition that typically leads to right heart failure and eventual death. The new findings, made in an animal study led by researchers at Beth Isra...Mouse Anti-Amodiaquine Monoclonal Antibody, Unconjugated, Clone 6D10 from AntibodyShop A/S
Description:Amodiaquine...Mouse Anti-Protein S Monoclonal Antibody, Unconjugated, Clone HYB 232-02 from Abcam
Description:Mouse monoclonal [HYB 232-02] to Protein S ( SwissProtID: P07225...Anti-S-100 protein, ab heterodimer Monoclonal Antibody, Unconjugated from HyTest Ltd.
Description:High affinity antibody reacting with S-100 ab heterodimer. Could be used for Western blotting application and immunoassay....Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
Weiping Yang Matt C. Petre Darrel Holmes Peter L.Pingerelli Stratagene Cloning Systems, Inc. Stratagenes IsoDetect mouse monoclonal antibody isotyping kit is asimple, rapid and sensitive method for identifying mouse monoclonal antibodyisotypes in a single step. Each IsoDetect test card...Two-dimensional Optimization of a Semi-nested PCR for Detecting Listeria monocytogenes
for Detecting Listeria monocytogenes Andrea Tanzer, Institute of Milk Hygiene, Milk Technology and Food Science, Austria Christian Rohrer, Eppendorf AG, Germany Introductio...Use of the DCode System to Detect the Food-Borne Bacterial Pathogen Listeria monocytogenes
Nikolaj Schmolker, Fintan van Ommen Kloeke and Gill Geesey, Departmentof Microbiology and Center for Biofilm Engineering, Montana State University,Bozeman, MT 59717-3980 Amplification of a region of the 16S rRNA gene of L. monocytogenes, Listeria innocua, and Listeria seeligeri by the polymerase chain reac...Novel Actemra monotherapy in treating patients with early aggressive rheumatoid arthritis
The first Phase III study involving the use of Actemra in the treatment of rheumatoid arthritis has revealed that it is superior to conventional treatment modality that uses disease modifying anti-rheumatic drugs (DMARDs to inhibit // joint destruction. It has also been found to provide symptomatic relief and improve sensation of pain. Rheumatoid arthritis is a debilitating autoimmune...Damage to arteries from injury can be avoided with carbon monoxide
Heart ailments that are treated with angioplasty or a transplantation may result in injury of the arteries. While in transplantation there is an ever-present risk of rejection of the// organ, in angioplasty, placing a balloon in the artery causes damage to the vessel walls. This in turn triggers the immune system response. A new study has however, revealed that pre-treatment with carbon m...Hearing loss can happen from regular exposure to carbon monoxide
Animal studies have shown the regular exposure to carbon monoxide can damage// the ears of young children. Carbon monoxide enters into the atmosphere from kerosene and gas stove combustions, generators and other liquid fuel powered equipments, car exhaust and tobacco smokes. At moderate concentrations carbon monoxide can cause angina, poor vision, and at times brain function impairment...9-PCV vaccine found to be helpful in invasive Pneumonococcal infection
Randomized double blind placebo controlled trial was done by Felicity cutts and colleagues in Gambia on the efficacy of // a Nine Valent Pneumococcal Conjugate Vaccine (9-PCV) against radiologically confirmed pneumonia and invasive pneumococcal disesase in children immunized before 12 months of age. The vaccine was found to reduce the incidence of vaccine type invasive pneumococcal dis...Self-Threading MONOKA (Fayet-Bernard Ritleng Type, PVP coating)
Description:This unique system uses prolene as thread-guide reducing time and trauma in lacrimal duct intubation. The hollow Ritleng Probe is inserted into the nasolacrimal duct and a thin prolene thread-guide is fed through it. The probe is then withdrawn leaving the polypropylene thread to pull the silicone tubing in place. Newly coated with a thin Polyvinylpyrrolidone (PVP) coating that makes the surface...Self-Threading MONOKA (Fayet-Bernard Ritleng Type, 3 mm COLLARETTE)
Description:This unique system uses prolene as thread-guide reducing time and trauma in lacrimal duct intubation. The hollow Ritleng Probe is inserted into the nasolacrimal duct and a thin prolene thread-guide is fed through it. The probe is then withdrawn leaving the polypropylene thread to pull the silicone tubing in place. Canalicular Laceration or Imperforate Nasolacrimal Duct. Silicone, Blue Polyproylen...Rapid Whole Blood Testing for Infectious Mononucleosis Antibodies
The Epstein Barr virus (EBV), which causes infectious mononucleosis (IM), is one of the most common human viruses. EBV occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95 percent of adults between 35 and 40 years of age have been infected. In most developed countries, including the U.S., infection with EBV most often occu...Opexa Advances Monocyte Derived Islet Technology to Proof of Principle in stz-induced NOD/SCID Mice
THE WOODLANDS, Texas--(BUSINESS WIRE)--Jun 27, 2007 - OpexaTherapeutics, Inc. (NASDAQ:OPXA), a company involved in thedevelopment and commercialization of cell therapies, presentedposter presentations at the 5th International Society for Stem CellResearch Annual Meeting (ISSCR) in Cairns, Queensland, Australiafrom June 17-20 and at the 13th Annual Meeting of the InternationalSociety for Cel...Phase I Results for ImClone Pipeline Anti-IGF-1R Monoclonal Antibody IMC-A12 Presented at ASCO
NEW YORK--(BUSINESS WIRE)--Jun 5, 2007 - First-in-human results forIMC-A12, a monoclonal antibody developed by ImClone SystemsIncorporated (NASDAQ: IMCL) and targeted to IGF-1R (insulin-likegrowth factor type 1 receptor), were presented at the annualmeeting of the American Society of Clinical Oncology in Chicago.The IGF-IR is expressed on the cell surface of must human cancersand transmits...