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Monkeys in Medical News

Why Chimps, Monkeys Don't Develop Alzheimer's

Study shows the plaques in non-human primates differ from those in humans MONDAY, May 25 (HealthDay News) -- Scientists have long noticed a curious phenomenon among primates: Humans get the devastating neurological disorder known as Alzheimer's disease, but their closest evolutionary c...

Vaccine Shields Monkeys From Simian Form of HIV

Scientists inject antibody-coding genes directly into muscles SUNDAY, May 17 -- Raising hopes for the development of an AIDS vaccine that might actually work, researchers report they were able to protect monkeys against infection with simian immunodeficiency virus (SIV), the primate ve...

College Kids and Monkeys About Equal on Math

It doesn't take language to do numbers, researcher explains FRIDAY, Feb. 13 (HealthDay News) -- Many primates are capable of basic math and pre-verbal "number sense," but it's the use of language to explain abstractions that allows humans to take math to much higher levels, says a Duke...

Subordinate monkeys more likely to choose cocaine over food

WINSTON-SALEM, N.C. Having a lower social standing increases the likelihood that a monkey faced with a stressful situation will choose cocaine over food, according to a study at Wake Forest University School of Medicine. More dominant monkeys undergoing the same stressful situation had fewer chan...

AVMA Urges Outlawing Trafficking of Chimps, Monkeys and Nonhuman Primates and Pets

SCHAUMBURG, Ill., March 11 /PRNewswire-USNewswire/ -- Citing concerns about the spread of disease and injury, inhumane treatment of animals, and ecological damage, Dr. Gail Golab, PhD, DVM, director of the American Veterinary Medical Association (AVMA) Animal Welfare Division, spoke on the dan...

Parasites a key to the decline of red colobus monkeys in forest fragments

Forest fragmentation threatens biodiversity, often causing declines or local extinctions in a majority of species while enhancing the prospects of a few. A new study from the University of Illinois shows that parasites can play a pivotal role in the decline of species in fragmented forests. This i...

Progression of SIV infection in monkeys raises

A sudden loss of T cells -- white blood cells crucial to the immune system -- is not the trigger for the onset of AIDS, according to a study published in the September 2007 issue of the Journal of Immunology by a team of researchers at Tulane National Primate Research Center. The study, Acute ...

Reduced diet thwarts aging, disease in monkeys

MADISON The bottom-line message from a decades-long study of monkeys on a restricted diet is simple: Consuming fewer calories leads to a longer, healthier life. Writing today (July 10) in the journal Science , a team of researchers at the University of Wisconsin-Madison, the Wisconsin Nationa...

Post-transplant combo can replace toxic immune-suppressing drugs in monkeys

Transplant patients rely on drugs to prevent graft rejection, but at the cost of serious side effects. The class of immunosuppressive drugs known as calcineurin inhibitors (examples are cyclosporine and tacrolimus) can damage patients' kidneys and lead to high blood pressure, among other problems....

Possible AIDS Treatment Shows Promise in Monkeys

It stops virus from fooling immune cells, researchers say WEDNESDAY, Dec. 10 (HealthDay News) -- Researchers report that a treatment under development appears to stop the equivalent of the AIDS virus in monkeys. Nine rhesus macaque monkeys infected with a virus known as SIV underwe...

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Monkeys in Medical Technology

Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions

...75% reduction at the highest dose accompanied by a significant increase (>100-fold) in glucose excretion in the urine in multiple species including monkeys Secondary improvements in glucose tolerance and insulin sensitivity Significant reduction in plasma glucose levels in extremely hyperg...

Human Genome Sciences Submits Biologics License Application to FDA for ABthrax(TM)

...cgi-bin/prnh/20080416/HGSLOGO ) The BLA submission includes the results of two randomized placebo-controlled studies conducted in rabbits and monkeys to evaluate the efficacy of raxibacumab. These studies showed a survival benefit in two relevant animal species, which is the requirement for establi...

Novel Vaccine Approach Offers Hope in Fight Against HIV

...les that block infection, the scientists protected monkeys from infection by a virus closely related to HIV -... administration of the AAV carriers, the immunized monkeys were injected with live, AIDS-causing SIV. The majority of the immunized monkeys were completely protected from SIV infection, and ...

ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients

...ek interim in both species, the No Observed Adverse Effect Level (NOAEL) in monkeys and male rats remains 1000 mg/kg at 13 weeks, the highest dose being tested...y in rats is now complete, while the dosing portion of the 39-week study in monkeys is scheduled to conclude in June. Anadys expects that the results from the...

Medarex Announces Preclinical Data from Multiple Research Programs Demonstrating Anti-Tumor Activity in Cancer

...monstrated significant anti-tumor activity at doses as low as 0.3 umole/kg. In addition, the antibody-drug conjugate was well-tolerated in cynomolgous monkeys and mouse models. The critical role of cleavable linkers for minor groove binding alkylating agent (MGBA) based antibody-drug conjugates (Abstr...

Anadys Pharmaceuticals Resumes Clinical Investigation of TLR7 Mechanism in HCV

...er therapeutic potential can be achieved without adverse toxicology findings. The immune stimulation observed with every-other-day dosing of ANA773 in monkeys included induction of interferon-alpha and interferon dependent responses at levels that are sustained over 13 weeks of dosing. The recently obtaine...

Infant Vaccines Produce Autism Symptoms in New Primate Study by University of Pittsburgh Scientists

...y 19 /PRNewswire-USNewswire/ -- Findings released Friday showed that infant monkeys given vaccines officially recommended by the CDC and the American Academy o...h (IMFAR) in London. Safety studies of medicines are typically conducted in monkeys prior to use in humans, yet such basic research on the current childhood va...

InterMune Announces Top-Line Results of Phase 1b Trial of ITMN-191 (R7227) and Provides Program Update

...pounds for the treatment of patients suffering from chronic HCV infection. InterMune also announced today that a 13-week chronic toxicology study in monkeys has been successfully completed and that this study supports the intended longer duration of dosing of ITMN-191 planned in the Phase 2 clinical develo...

Idenix Pharmaceuticals Provides Update on Hepatitis C Pipeline at JP Morgan Healthcare Conference

... clinical development. In a 7-day preclinical toxicology study of IDX184, no toxicities, including gastrointestinal or hematological, were observed in monkeys at doses greater than or equal to 600 mg/kg/day. In HCV genotype-1 infected chimpanzees, once- daily oral administration of 10 mg/kg of either nucleot...

New Approach to Treating Anthrax Significantly Improves Survival Rates in Pivotal Efficacy Studies

...gs In one of the animal studies, three groups of monkeys were exposed by inhalation to anthrax spores and t...ys, the study found that: -- 64.3 percent of monkeys that received a single high dose of ABthrax su...rvived (p=0.0064 vs. placebo). -- None of the monkeys in the placebo control group survived. A separate...
Monkeys in Medical Dictionary

Yellow Fever

...uses of ... Yellow fever is caused by a virus that is spread by several species of Aedes and ... The natural sources of yellow fever are monkeys and mosquitoes, which inhabit ... ...

Shigellosis

...ne illness caused by infection by bacteria of the genus Shigella. Shigellosis rarely occurs in animals other than humans and other primates like monkeys and chimpanzees. The... Shigellosis is an intestinal infection caused by bacteria that can give a person ... How Is Shigellosis Diagnosed ...

Semicircular canals

...the vestibule ... Semicircular canals . 16. ... 22. Semicircular canals . 23. Cochlear duct. MULTIPLE CHOICE. Choose ... ... (VOR) in rhesus monkeys following plugging of the lateral semicircular canals . ... Based on this hypothesis, semicircular canal plugging has been used to ... ...

Retrovirus

...an Retrovirus Laboratory, California Regional Primate Research Center, ... Simian type D retrovirus (SRV) is enzootic in many populations of Asian monkeys ... ...

Lesion

... eosinophilic ... Electron microscopic examination of the lesion did not demonstrate Birbeck granules. ... JOV article - Is residual vision in monkeys with unilateral lesion in the primary visual cortex like normal, near-threshold vision? by Yoshida, Takaura, & Isa List of 16 disease ca...

Feces

... disease that ... CPV is hardy and can remain in feces -contaminated ground for five months or more ... feces - 20 definitions - 1: the stuff monkeys throw at each other and later sniff for pleasure (think of it as monkey cocaine) 2: crap Did President Bush misspeak and say ' feces ' instead of ...

Ebola Virus

...close cousins, but the Marburg virus is not a form of Ebola ... ... monkeys from the Ebola virus , a microbe that has devastated several African ....t's New ... Ebola -Reston virus caused severe illness and death in monkeys imported to ... People can be exposed to Ebola virus from direct contac...
Monkeys in Biological News

Bolivian rainforest study suggests feeding behavior in monkeys and humans have ancient, shared roots

Behavioural ecologists working in Bolivia have found that wild spider monkeys control their diets in a similar way to humans, contrary to what has been thought up to now. Rather than trying to maximize their daily energy intake, the monkeys tightly regulate their daily protein intake, so that it s...

Simian foamy virus found in several people living and working with monkeys in Asia

A research team led by University of Washington scientists has found that several people in South and Southeast Asian countries working and living around monkeys have been infected with simian foamy virus (SFV), a primate virus that, to date, has not been shown to cause human disease. The findings...

Ugandan monkeys harbor evidence of infection with unknown poxvirus

Researchers report this month that red colobus monkeys in a park in western Uganda have been exposed to an unknown orthopoxvirus, a pathogen related to the viruses that cause smallpox, monkeypox and cowpox. Most of the monkeys screened harbor antibodies to a virus that is similar but not identica...

Moderate prenatal exposure to alcohol and stress in monkeys can cause touch sensitivity

A new study on monkeys has found that moderate exposure to alcohol and stress during pregnancy can lead to sensitivity to touch in the monkeys babies. In human children, sensitivity to touch is one of a number of characteristics of the approximately 5 percent of children who over-respond to senso...

Island monkeys do not recognize big cat calls

Monkeys living on an island without big cat predators do not show any particular alarm when recorded tiger growls are played to them, according to research by a UC Davis graduate student. The pig-tailed langurs do, however, flee in a hurry from the sound of human voices. "This contributes to a ...

Penn researchers find monkeys able to fend off AIDS-like symptoms with enhanced HIV vaccine

(PHILADELPHIA) Researchers at the University of Pennsylvania School of Medicine have discovered that using an immune system gene to enhance a vaccine used to study HIV in macaque monkeys provides the animals with greater protection against simian HIV (SHIV) than an unmodified vaccine. This multi-...

Humans and monkeys share Machiavellian intelligence

When it comes to their social behavior, people sometimes act like monkeys, or more specifically, like rhesus macaques, a type of monkey that shares with humans strong tendencies for nepotism and political maneuvering, according to research by Dario Maestripieri, an expert on primate behavior and a...

Influence of sex and handedness on brain is similar in capuchin monkeys and humans

Hiram, Ohio, August 29, 2007 Capuchin monkeys are playful, inquisitive primates known for their manual dexterity, complex social behavior, and cognitive abilities. New research now shows that just like humans, they display a fundamental sex difference in the organization of the brain, specifical...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

Anthrax vaccine administered in combination with a short course of antibiotics completely protected nonhuman primates from inhalational anthrax, the most lethal form of the disease, according to scientists at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). In a collab...

Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research

Scientists investigating the genetic makeup of rhesus macaque monkeys, a key species used in biomedical research, have found the rhesus in Nepal may provide a suitable alternative to alleviate a critical shortage of laboratory animals used in work to develop vaccines against diseases such as HIV/AI...

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Monkeys in Biological Technology

Combination vaccine protects monkeys from ebola and Marburg viruses

An experimental, combination vaccine against Ebola and Marburg viruses using virus-like particles (VLPs) provides complete protection against infection in monkeys. Researchers from the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) report their results today (Feb. 26) at ...

Practice makes perfect -- motor memory possible for neuroprosthetic control

... PLoS Biology , new research reveals that macaque monkeys can achieve a kind of consolidation of motor memor...University of California, Berkeley, taught macaque monkeys to use their own brain signals to move a computer ...ious targets using a prosthetic device, and as the monkeys learned to proficiently use the robotic device, th...

Anadys Pharmaceuticals Reports First Quarter 2009 Financial Results and Highlights

...ek interim in both species, the No Observed Adverse Effect Level (NOAEL) in monkeys and male rats remains 1000 mg/kg at 13 weeks, the highest dose being tested...y in rats is now complete, while the dosing portion of the 39-week study in monkeys is scheduled to conclude in June. Anadys expects that the results from the...

Idenix Pharmaceuticals Reports Data From Three Hepatitis C Development Programs at the 44th Annual Meeting of the European Association for the Study of the Liver

...5 showed limited metabolism and no cytotoxicity when incubated with mouse, rat, monkey or human hepatocytes. IDX375 demonstrated no adverse effects in monkeys given daily oral doses of 10 or 100 mg/kg for 7 days. About Idenix Idenix Pharmaceuticals, Inc., headquartered in Cambridge, Massachusetts,...

PharmAthene Presents Data for SparVax(TM) and Valortim(R), a Novel Vaccine and Anti-Toxin for the Prevention and Treatment of Anthrax Infection at the 7th Annual ASM Biodefense Meeting

..., 2009. Inhalational anthrax in certain primates such as African Green monkeys (AGMs) and cynomolgus monkeys (cynos) is believed to follow a similar disease course as in humans. Valort...

Proteolix Presents Preclinical Data for Oral Proteasome Inhibitor PR-047 at the 50th Annual Meeting of the American Society of Hematology

...ymotrypsin-like activity of the proteasome and induce tumor cell death across multiple human cell lines. Oral administration of PR-047 in rodents and monkeys resulted in rapid and prolonged dose-dependent inhibition of the proteasome. Furthermore, significant proteasome inhibition was achieved at doses wel...

Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients

...er therapeutic potential can be achieved without adverse toxicology findings. The immune stimulation observed with every-other-day dosing of ANA773 in monkeys included induction of interferon-alpha and interferon dependent responses at levels that are sustained over 13 weeks of dosing. Clinical Need and Ma...

GenOdyssee Receives Broad Product Applications Protection in EU for Founding Natural Evolution Technology

...on assay without significantly increased toxicity as demonstrated in Rhesus monkeys compared to standards of care IFN alpha 2 molecules. GEA007.1 product paten...ed in IFN alpha 2 treated cells. - Similar safety pharmacology in rhesus monkeys (Macaca mulatta) to IFN alpha 2. - Importantly, GEA007.1 is a natural hu...

Scientists restore movement to paralyzed limbs through artificial brain-muscle connections

...brain to muscles can restore voluntary movement in monkeys whose arms have been temporarily anesthetized. Th...esources. In the study, the researchers trained monkeys to control the activity of single nerve cells in t...e neural activity led to movements of a cursor, as monkeys played a target practice game. After each monke...

InterMune Earns Development Milestone in HCV Protease Inhibitor Collaboration With Roche

...ty and excellent safety and tolerability in all dosage regimens. Also in early April, InterMune announced that 13-week preclinical studies in rats and monkeys were successfully completed which were necessary before initiation of clinical studies in Phase 2 with longer treatment durations than those performed...
Monkeys in Biological Products

Rhesus Serum from Innovative Research

Description:... Rhesus Serum • Rhesus serum is collected from fasted Rhesus monkeys of mixed sex and 5-7 years of age. Available Anticoagulants: N-02: Citrate N-04: Heparin (Na) N-06: K2EDTA N-08: Potassium Oxalate N-10: ...
Company:Innovative Research

Cyno Serum from Innovative Research

Description:... Cyno Serum • Cyno serum is collected off the clot from fasted Cynomolgus monkeys of mixed sex and 5-7 years of age. Available Anticoagulants: N-02: Citrate N-04: Heparin (Na) N-06: K2EDTA N-08: Potassium Oxalate N-10: ...
Company:Innovative Research

8-iso-13,14-dihydro-15-keto Prostaglandin F2alpha from Cayman Chemical

Description:...rostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane ...
Company:Cayman Chemical
Monkeys in Biological Definition

Charles Darwin

...ctorian stage. On being asked by Wilberforce, whether he was descended from monkeys on his grandfather's side or his grandmother's side, Huxley, recognizing hi... Descent of Man that he felt more kin to certain altruistic tendencies in monkeys than he did "from a savage who delights to torture his enemies." He further...

Ebola

...irus was identified in Reston , Virginia among monkeys imported from the Philippines , and was named E...ne fell ill. Ebola–Reston has re-emerged in monkeys several times since then, but no humans have cont...rrhagic Fever Table”). It is unknown why the monkeys became ill, but not the humans (Draper 40). ...

Thermoregulation

...n is also reversed. The diurnal temperature curve follows the periods of rest and activity, and is not dependent on the incidence of day and night; in monkeys which are active during the night and resting during the day, the body temperature is highest at night and lowest through the day. They then made obse...

Yellow fever

... Flaviviridae , and is one of the smallest RNA viruses isolated from man. Mosquitos are the primary in transmission of the disease from forest monkeys to man and in man-to-man transmission. The mosquitos involved are Aedes simpsoni , Aedes africanus , and Aedes aegypti in Africa; and the H...
Monkeys in Biological Dictionary

Sub-cloning

... resource from the PUBLIC ... Sub - cloning vector-derived fragments requires the donor fragment to be excised ... China to Try Cloning of Rare monkeys - Using advanced technology to research ... Online - An online program finding sub - cloning strategies,in-frame deletions and ... Allele Biotech...

Proboscis

...nservation mangrove swamp area to view proboscis monkeys living in the wild. Information about probosci...rd games. Specialized plant-eaters, proboscis monkeys appear permanently potbellied ... Proboscis monkeys need large tracts of forest to sustain their dwind...

Mammals

...ifornia Museum of Paleontology. A group of warm-blooded animals with a bony skeleton, mammals include mice and other RODENTS, PRIMATES, such as monkeys and humans, and animals as var Mammal , animal that raises its young on milk. ... Most mammals are covered with hair or fur, and most have s...
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