Molecule

Chemists create 'Superbowl' molecule; May lead to better health

In a development that could one day score a touchdown for better health, chemists in Australia have created a "superbowl" molecule that shows promise for precision drug delivery, according to a recent study in the Journal of the American Chemical Society. Shaped like a miniature football stadium, the molecule is capable of delivering a wide range of drugs ?from painkillers to chemotherapy cocktai...

DNA Molecules Used To Assemble Nanoparticles

University of Michigan researchers have developed a faster, more efficient way to produce a wide variety of nanoparticle drug delivery systems, using DNA molecules to bind the particles together. Nanometer-scaled dendrimers can be assembled in many configurations by using attached lengths of single-stranded DNA molecules, which naturally bind to other DNA strands in a highly specific fash...

Key molecule in plant photo-protection identified

Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characteristic brain plaques are removed.Researchers at Washington University School of Medicine in St. Louisinjected mice with an antibody for a key component of brain plaques,the amyloid beta (Abeta) peptide. In areas of the brain whereantibodies cleared plaque...

Inflammatory molecules released by pollen trigger allergies

How do pollen particles provoke allergic reactions? A new study in the February 21 issue of The Journal of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoting immune response. Pollen from plants exposed to air pollutants produce more of these allergy-provoking c...

Researchers discover molecule that causes secondary stroke

Scientists at the University of Cincinnati (UC) College of Medicine have discovered the cause of a deadly type of secondary stroke known as cerebral vasospasm. A constriction of the blood vessels in the brain, cerebral vasospasm usually occurs three to 10 days following a massive brain bleed known as hemorrhagic stroke. Sixty percent of patients who survive the initial stroke develop vasos...

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Molecule at Biology Products

Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.

Description:ions and aligns them with histological images so you can localize drugs and metabolites prior to synthesizing radiolabeled c...
Company:Protein Discovery, Inc.

StabilGuard Biomolecule Stabilizer from SurModics, Inc.

Description:StabilGuard Biomolecule Stabilizer is a bovine protein-free alternative to StabilCoat Immunoassay Stabilizer. It is an aqueous solution that contains non-toxic chemicals in a PBS buffer (phosphate buffered saline), pH 6.6 - 7.2, and does not contain a preservative. This product maintains the activity of antibodies and other biomolecules that are absorbed or immobilized to solid substrates, by s...
Company:SurModics, Inc.

Mouse Anti-L1 Cell Adhesion Molecule Monoclonal Antibody, Unconjugated, Clone UJ127 from GeneTex

Description:Mouse Monoclonal to L1 Cell Adhesion Molecule Homogenous suspension of 16 week human fetal brain...
Company:GeneTex

Molecule at Biology Technology

Small-Molecule Quantitation Using Automated Single-Shot Averaging MALDI-TOF Mass Spectrometry

Traditionally, MALDI-TOF mass spectrometry has been used very little for quantitative studies. Analysts have usually assumed that potential differences in ionization efficiency between analyte and internal standards and an inherent heterogeneity of the sample spot would limit MALDI-TOF mass spectrometry as a quantitative technique. In addition...

GenTel will sell Dutch firm's biomolecule labeling technology

GenTel will market and sell the Universal Linkage System labeling reagents of o...

Molecule at Biology Definition

Macromolecule

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Molecule at Biology Dictionary

Recombinant DNA molecule

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Macromolecules

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Molecule at Medicine News

Poisonous Parkinson's molecule discovered

Researchers in Texas have found a molecule which may harm the brain areas involved in Parkinson's disease. There is no firm diagnostic test for Parkinson's disease - the doctor has to rely on the clinical examination of the patient. But it's known that cells producing a chemical called dopamine - which controls muscle activity - in an area of the brain called the substantia nigra slowly die as th...

Glenmark’s new molecule to go through trial

Glenmark Pharmaceuticals Ltd today said its newly- found andti-diabetic/anti-obesity molecule will be put into clinical trials by later this year. Mr Glenn Saldanha, Executive Director, Glenmark pharmaceuticals, told newspersons that the company’s R&D team has established ‘proof of concept’ in animals for this molecule.// The global diabetes market is estimated to be in the region of...

Resistant tumors could be treated with the discovery of a new molecule within cancer cells

A new research study published in the journal, Cancer Cell reported that scientists have discovered why some tumors respond less well to drug treatment as compared to others. Researchers have found that high levels of a specific molecule within cancer cells seem to block the effect of drugs such as Taxol, which are used to treat a number of cancers in their later stages. In the study, the// resea...

Ways to counter radiation effects with new molecule discovery

Radiation inflicts serious damage to the DNA within our cells, which could lead to cancer. However, researchers have now found a molecule that triggers a protective mechanism in the body, which both repairs the damage and induces severely damaged cells to destroy themselves. The molecule called MDC1, which initiates this protection mechanism, was discovered by researchers at the Institute of Canc...

Same molecule found in meat, milk, tumors

A non-human molecule found in red meat and milk makes its way into the human system when eaten -- and seems to build up especially in tumors, say researchers.// The compound, called sialic acid, is found on the surfaces of animal cells but is not found in people, and may be one reason why animal-to-human organ and tissue transplants do not work well. Animals have a version called Neu5Gc...

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Molecule at Medicine Products

PTH Intact Molecule with Calcium

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

PTH Intact Molecule

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Molecule at Medicine Technology

Halozyme Therapeutics' Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society

- Co-Injection of rHuPH20 with Humira Estimated to Increase theMaximal Steady State Subcutaneous Bioavailability from 64% to 100%- SAN DIEGO, July 09, 2007 /PRNewswire-FirstCall/ -- HalozymeTherapeutics, Inc. , a biopharmaceutical company developing andcommercializing recombinant human enzymes, today announced thatfinal results of the Enhanze(TM) Technology clinical trialdemonstrating im...

Anadys Pharmaceuticals Nominates ANA598, a Small-Molecule, Non-Nucleoside Inhibitor of The NS5b Polymerase, as a Candidate for Clinical Development in Chronic Hepatitis C Virus Infection

SAN DIEGO, June 20, 2007 /PRNewswire-FirstCall/ -- AnadysPharmaceuticals, Inc. , a biopharmaceutical company committed tothe discovery, development and commercialization of novel medicinesfor the treatment of hepatitis and cancer, announced today that ithas nominated ANA598 as a candidate for clinical development as anorally-administered direct antiviral for the treatment of chronichepat...

Prolexys Pharmaceuticals and Columbia University Researchers Publish Study on Anti-Tumor Properties of a Selective Small Molecule Anti-Tumor Agent With Novel Mechanism of Action

SALT LAKE CITY, June 14, 2007 /PRNewswire/ -- ProlexysPharmaceuticals and announced today a publication describing theproperties of the selective small molecule anti-tumor agent,erastin. Prolexys and Columbia applied the company'schemi-proteomics technology to understand the mechanism of actionof erastin. The results, to be published in the June 14, 2007 issueof the journal Nature reveal...

MedImmune and Micromet Publish Data on Novel Anti-Cancer BiTE Molecule

- New Compound Targeting Receptor Tyrosine Kinase EphA2 Shows TumorDestruction at Low Dose Levels in Preclinical Models - GAITHERSBURG, Md. and CARLSBAD, Calif., April 19, 2007/PRNewswire-FirstCall/ -- MedImmune, Inc. and Micromet, Inc. todayannounced that published proof-of-concept data with a new BiTE(R)molecule (bscEphA2xCD3) show that the compound killed tumor cellsat dose levels cons...

Micromet and MedImmune Present Data From Preclinical Study of New BiTE Molecule Targeting CEA

GAITHERSBURG, Md. and CARLSBAD, Calif., April 18, 2007/PRNewswire-FirstCall/ -- Micromet, Inc. and MedImmune, Inc. todayannounced data from a preclinical study in which BiTE(R) moleculestargeting carcinoembryonal antigen (CEA) were shown to preventsubcutaneous tumor growth and formation of lung metastases. Anestablished marker for tumor progression, CEA is frequentlyexpressed on breast,...

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