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Microbicides in Medical News

International Partnership for Microbicides Receives US $130 Million from UK Government and the Gates Foundation

New support will accelerate development of new tools to help women protect themselves from HIV SILVER SPRING, Md., Feb. 24 /PRNewswire-FirstCall/ -- The International Partnership for Microbicides (IPM) announced today that it has received a total of US $130 million in grants from the UK Depar...

Vaginal Microbicides Might Help More Men Than Women

Researchers say clinical trials' design may also mask risk of HIV drug resistance THURSDAY, July 10 ( HealthDay News) -- A new study questions whether vaginal microbicides being developed to help protect women against HIV infection could lead to new drug resistance from the virus that ...

Researchers develop new tool to predict who will use microbicides

Providence, RI Using a new tool designed to measure a womans willingness to use a microbicide (topical gels designed to prevent the sexual transmission of HIV), researchers at The Miriam Hospital and Brown University found that women who have used protective methods in the past, and those with ca...

Computer Tool Predicts Effectiveness Of Microbicides

Duke University biomedical engineers have announced that they have created a computer tool that can increase the effectiveness of the topical microbicides// used by women for preventing HIV infections. Researchers said that microbicides are needed since the infections globally are soaring. By...

Shifting Scientific, Health Priorities and Global Economic Downturn Impact Investment in HIV Prevention R&D

...om 2007 levels. At the same time, funding for both microbicides and pre-exposure prophylaxis (PrEP) increased by e...al (ARV)-based candidates. Investment increased in microbicides overall at the same time that the field intensifie...cal transmission. The HIV Vaccines and microbicides Resource Tracking Working Group was established i...

Family Health International Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research Project Led by David Sokal, M.D.

...nces group, is building on past successes in developing new reproductive health technologies. Dr. Sokal has invented a device for delivery of vaginal microbicides using low-cost non-woven materials, and has obtained two patents for this novel vaginal device. He also has a patent for a new method of nonsurgical ...

Clinical trial finds microbicide promising as HIV prevention method for women

...et say that we have an effective microbicide." microbicides are substances intended to reduce or prevent the s...fections when applied topically. Several candidate microbicides are being tested in clinical trials, although none...ated the safety and effectiveness of two candidate microbicides for preventing male-to-female sexual transmission ...

Anti-HIV gel shows promise in large-scale study in women

...uccessfully met its goal of determining whether either of the two candidate microbicides had sufficient promise to be considered for testing in a larger Phase III c...ression and treatment response in HIV-infected women who were using topical microbicides or oral antiretrovirals as an HIV preventive measure when they acquired HIV...

HIV Can Penetrate a Woman's Healthy Genital Skin

... actually works. The mechanism was all very murky," Hope said. These findings, if confirmed in future studies, could help in the development of new microbicides and vaccines to protect women against HIV. "We urgently need new prevention strategies or therapeutics to block the entry of HIV through a woman's ...

Ford Foundation Says Rights and Opportunity Are Critical for People Living Longer with HIV

...ions are made that affect their lives. The Collective has also launched the microbicides Advocacy Project (MAP) to ensure that women living with HIV/AIDS are part of microbicides clinical trials so that they too will have access to the prevention tool wh...
Microbicides in Medical Technology

ImQuest Scientists Present Important HIV Microbicide Development Results at Microbicides 2008 in Delhi, India

FREDERICK, Md., April 8, 2008 /PRNewswire/ -- ImQuest scientists Robert W. Buckheit, Jr., Ph.D. and Karen M. Watson, M.S. presented the results of studies performed with products licensed by ImQuest Life Sciences, Inc. at the recent Microbicides 2008, an international conference held in New De...

New PRO2000 HIV-Prevention Findings Important Milestone on Path Toward Development of Effective Vaginal Microbicide

...RO2000 (0.5 percent concentration) by the UK-based microbicides Development Programme (MDP), a partnership of Afri...esult that helps validate the safe introduction of microbicides into communities. This trial and the others ...als (ARVs) that specifically target HIV. These ARV microbicides are based on the same antiretroviral drugs being u...

Indevus Pharmaceuticals Announces PRO 2000 Found to Show Promise in Large HIV Prevention Study

...by the United Kingdom's Medical Research Council (MRC) and conducted by the microbicides Development Programme (MDP), an international partnership of researchers established to develop microbicides for the prevention of HIV transmission. Study MDP 301 is a multi-national,...

Indevus Pharmaceuticals Announces Completion of Enrollment in Phase III Trial of PRO 2000

... partnership of researchers established to develop microbicides for the prevention of HIV transmission. This trial...treotide implant for acromegaly. About MDP The microbicides Development Programme (MDP) is an Afro-European partnership to develop vaginal microbicides for the prevention of HIV transmission. MDP is coo...

ImQuest Receives Two Year Phase 2 SBIR Grant to Develop Pyrimidinedione Product as an Anti-HIV Topical Microbicide

...ID/NIH) to support the development of pyrimidinedione inhibitors as topical microbicides to prevent the sexual transmission of HIV. The two year Small Business Inno...," explained Dr. Buckheit. "In the absence of an effective vaccine, topical microbicides represent the best means to prevent new HIV infections throughout the world...

HIV Prevention Expert Dr. Timothy Mastro Speaks on Future of Pre-Exposure Prophylaxis at International AIDS Conference

...is tenure at the CDC, Dr. Mastro oversaw HIV prevention research activities, including a landmark study on mother-to-child HIV transmission, trials of microbicides for women, and the first international HIV vaccine efficacy trial. He has also served as chief of the CDC HIV Vaccine Section and directed CDC's parti...

Microbicide Developer Receives License for Novel HIV Microbicide Candidate From Merck & Co., Inc.

...the class of molecules known as CCR5 blockers. microbicides are products, such as gels or films, that could be...d the world will have access to safe and effective microbicides -- and partnerships like this will help us get the...linical trial late in 2009. Safe and effective microbicides could provide women in the developing world with a...

Indevus Pharmaceuticals Provides Update on PRO 2000 Program

...ared to placebo gel. The trial is sponsored by the MRC and conducted by the microbicides Development Programme (MDP), an international partnership of researchers established to develop microbicides for the prevention of HIV transmission. The 0.5% dose of PRO 2000 is also b...
Microbicides in Biological News

Agreement will speed research on microbicides for women

Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or unusually severe infections, according to new findings reported in the August issue of Nature Genetics. The discovery may lead to new diagnostic tests for these two inherited...

International trial of two microbicides begins

A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National In...

New lab test offers better prediction of HIV microbicide safety

...e devised a laboratory test for predicting whether microbicides against HIV are safe for human use. The researcher...have also discovered why several supposedly "safe" microbicides made women more susceptible to HIV infection. The ...safety tests. But with just one exception, all the microbicides were found to be ineffective against HIV; and two ...

Scientists develop a new HIV microbicide -- and a way to mass produce it in plants

...nior researcher involved in the work. "A vaccine is still some way off, but microbicides could provide a more immediate solution, provided we can overcome major hur...he research paper, Ma and colleagues describe how they combined two protein microbicides (b12 monoclonal antibody and cyanovirin-N) into a single "fusion" molecule ...

Cutting-edge amfAR grants fight HIV/AIDS in the lab and on the phone

...ni, Ph.D./Mentor: Joseph Sodroski, M.D. Dana-Farber Cancer Institute, Boston, MA $125,000 A chemical campaign to identify HIV-1 entry inhibitors: microbicides have been envisioned as a means of preventing the sexual transmission of HIV, but to date human trials of such products have not been successful. Prev...

CONRAD receives $28.5M Gates Foundation grant for HIV prevention research

...rom the Bill & Melinda Gates Foundation to develop microbicides for HIV prevention. To date, the Gates Foundation...ment to making real progress in global health. microbicides are topical substances used intravaginally to potentially prevent HIV infection. Effective microbicides could be an important HIV prevention option for wo...

UCSF study will test new vaginal microbicide for herpes and HIV

...oscicki said that the safety trial is important because earlier spermicidal microbicides like nonoxynol 9, which was an ingredient in a variety of contraceptive pro...rate of HIV infection in women. So now we realize that we must approach new microbicides a little more carefully," Moscicki said. According to the U.S. Centers...

Study defines effective microbicide design for HIV/AIDS prevention

...ool they say could lead to improvements in topical microbicides being developed for women to use to prevent infect...that causes AIDS. Providing women with improved microbicides is a pressing challenge because women now account ...eir delivery. "There is a huge push to produce microbicides that would have any effectiveness at all in reduci...

New licensing agreement to maximize AIDS drug development

...a non-exclusive licensing agreement to research and develop Biosyn-patented microbicides for the prevention of HIV and other sexually transmitted diseases. The three microbicides covered under the agreement are in various stages of development and work u...

Anti-HIV drug has potential to prevent transmission in women

...so safe when applied as a vaginal microbicide gel. microbicides are designed to prevent the sexual transmission of...gel can prevent HIV from replicating, unlike other microbicides which have been designed to block HIV entry into c...sts while using the gel. Past safety trials of microbicides showed that certain gels caused ulcerations and in...
Microbicides in Biological Technology

ImQuest Receives $6.4 M Five Year Award from NIH to Develop Long-Lasting Combination Topical Microbicides To Prevent HIV Transmission

FREDERICK, Md., Aug. 6 /PRNewswire/ -- ImQuest BioSciences announced today the successful acquisition of funding from the National Institutes of Health to support the development of a long lasting, safe, and acceptable combination topical microbicide product. ImQuest and a consortium of microb...

Vaxart Demonstrates Efficacy of Oral Avian Flu Vaccine in Preclinical Studies

...u vaccine was protective against lethal exposure to H5N1 influenza. Tucker presented the data this morning at the Modern Mucosal Vaccines, Adjuvants & microbicides (MMVAM) international conference in Porto, Portugal. Delivery of flu vaccine via a capsule rather than an injection offers critical advantages, part...
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