ImQuest Presentations at Keystone Symposium Focus on Advancements in Their Therapeutic and Microbicide Development Programs

FREDERICK, Md., March 25 /PRNewswire/ -- ImQuest Life Sciences presented their latest biological results supporting the continued development of their small molecule pyrimidinedione inhibitors of HIV-1 at the Prevention of meeting being held in Keystone, Colorado. The presentations highlighted new...

Clinical trial finds microbicide promising as HIV prevention method for women

March 5, 2009 -- A clinical trial involving more than 3,000 women in the U.S. and southern Africa demonstrates for the first time the promise of a vaginal microbicide gel for preventing HIV infection in women. According to findings presented at the Conference on Retroviruses and Opportunistic Infe...

ImQuest Presents New Anti-HIV Drug and Topical Microbicide Development Results on Lead Pyrimidinedione Products IQP-0410 and IQP-0528

FREDERICK, Md., April 16 /PRNewswire/ -- ImQuest Life Sciences today presented important new results on the development of their lead anti-HIV therapeutic development candidate, IQP-0410, and lead topical microbicide development candidate, IQP-0528. ImQuest scientists Robert W. Buckheit, Jr., ...

HIV Drug in Microbicide Gel Safe for Daily Use

None of the 200 women volunteers got HIV during 6-month study TUESDAY, Feb. 26 (HealthDay News) -- A vaginal microbicide gel that contains the antiretroviral drug tenofovir is safe for HIV-negative women to use every day, according to a six-month study of 200 women in India and the Un...

IPM Reaches Landmark Agreement with Pfizer to Develop FDA-Approved Antiretroviral Drug as Vaginal Microbicide

SILVER SPRING, Md., Jan. 30 /PRNewswire-USNewswire/ -- Expanding the pipeline of HIV prevention tools in development, the International Partnership for Microbicides (IPM) today announced that Pfizer Inc. (Pfizer) has agreed to give IPM a royalty-free license to maraviroc, its newly-approved HI...

Protection against HIV and Herpes is possible with the Experimental Microbicide

Indevus Pharmaceuticals have come out with a new experimental Microbicide PRO 2000. This protects a person against contracting HIV and the herpes simplex virus. The findings of the study were published in the journal // of infectious diseases. Microbicides are products such as gels, films a...

Dr. Liza Solomon, HIV/AIDS Expert, Joins Abt Associates as Principal Associate in Company's Domestic Health Division

...r all CDC funded prevention activities in the state. Immediately prior to joining Abt Associates, Dr. Solomon was deputy director of the Alliance for microbicide Development, an international non-profit organization dedicated to encouraging the development of female-controlled HIV and STI preventive agents. Pre...

VivaGel(R) Demonstrates Anti-HIV and Herpes Activity Following Human Administration

... and HSV in more than half of the women enrolled in the study. This is the first clinical study to demonstrate potent antiviral activity of any microbicide beyond one hour after administration of the product in humans. These data indicate the potential for VivaGel(R) to be used other than immediately prio...

Shifting Scientific, Health Priorities and Global Economic Downturn Impact Investment in HIV Prevention R&D

...n in Cape Town South Africa by the HIV Vaccine and microbicide Resource Tracking Working Group. It is available o...ported vaccine R&D, and $244 million supported microbicide R&D, while other HIV prevention R&D receiv... and as oral PrEP, along with technical support to microbicide product developers. "The worldwide econ...

Piecing Together the HIV Prevention Puzzle

... AVAC Report Assesses Progress in AIDS Vaccine, microbicide and PrEP Research and Calls for Urgent Coordinatio... Positive results from current vaccine, PrEP and microbicide trials will also present challenges and opportunit... results from PrEP trials would require vaccine or microbicide trials to become larger, longer and more expensive...

microbicide in Medical Technology

ImQuest Scientists Present Important HIV Microbicide Development Results at Microbicides 2008 in Delhi, India

FREDERICK, Md., April 8, 2008 /PRNewswire/ -- ImQuest scientists Robert W. Buckheit, Jr., Ph.D. and Karen M. Watson, M.S. presented the results of studies performed with products licensed by ImQuest Life Sciences, Inc. at the recent Microbicides 2008, an international conference held in New De...

Microbicide Developer Receives License for Novel HIV Microbicide Candidate From Merck & Co., Inc.

SILVER SPRING, Md., March 11 /PRNewswire-USNewswire/ -- In a boost to HIV prevention research, Merck & Co., Inc., has agreed to provide a royalty-free license to the non-profit International Partnership for Microbicides (IPM) to develop a novel antiretroviral compound for use as a potential va...

New PRO2000 HIV-Prevention Findings Important Milestone on Path Toward Development of Effective Vaginal Microbicide

Dr. Zeda Rosenberg, CEO of the International Partnership for Microbicides, issued the following statement on the results of the Phase II/IIb safety and effectiveness study of BufferGel and PRO2000 (0.5 percent concentration): SILVER SPRING, Md., Feb. 9 /PRNewswire/ -- The Microbicide Trials N...

ImQuest Receives Two Year Phase 2 SBIR Grant to Develop Pyrimidinedione Product as an Anti-HIV Topical Microbicide

FREDERICK, Md., July 29 /PRNewswire/ -- ImQuest BioSciences announced today the successful acquisition of funding from the National Institute of Allergy and Infectious Disease (NIAID/NIH) to support the development of pyrimidinedione inhibitors as topical microbicides to prevent the sexual tra...

HIV/AIDS Research Network Recommends Use of Abbott RealTime Viral Load Test for NIH-Sponsored Clinical Trials

...l Trials Group, International Maternal Pediatric Adolescent AIDS Clinical Trials Group, HIV Prevention Trials Network, HIV Vaccine Trials Network, and microbicide Trials Network. The networks are an affiliated group of national and international medical research institutions and investigators that conduct clinic...

ImQuest BioSciences Receives Phase I SBIR Grant to Develop a Novel Hepatitis C Virus Therapeutic Agent

... ImQuest BioSciences Inc. is a privately held U.S. company located in Frederick, Maryland, is a leading provider of anti-infective therapeutic and microbicide development services to the biotechnology and pharmaceutical industry. Arisyn Therapeutics Inc. is a privately held virtual biotechnology com...

Indevus Pharmaceuticals Announces PRO 2000 Found to Show Promise in Large HIV Prevention Study

...received PRO 2000, the Company's candidate vaginal microbicide for HIV prevention, had an approximately 30% lower...ounseling. This is the first trial to suggest any microbicide may prevent male-to-female sexual transmission of ...ss of PRO 2000 and another investigational vaginal microbicide (BufferGel(R), ReProtect, Inc.) in preventing HIV ...

ImQuest Submits Investigational New Product Application to the Food and Drug Administration to Initiate HIV Therapeutic Clinical Trials with IQP-0410

...o develop additional pyrimidinediones as next generation NNRTIs with an enhanced genetic barrier to resistance as well as efforts to develop a topical microbicide to prevent the sexual transmission of HIV. Additionally, ImQuest's development of Samjin's piperazine anti-tumor agents for the treatment of both soli...

Indevus Pharmaceuticals Announces Completion of Enrollment in Phase III Trial of PRO 2000

...trial of PRO 2000, the Company's candidate vaginal microbicide for the prevention of HIV and other sexually trans...0.5% dose of PRO 2000 and the largest trial of any microbicide to date. In July 2007, enrollment of 3,100 women w...tiveness of PRO 2000 and another candidate vaginal microbicide in preventing HIV infection in women. This trial w...

New AVAC Report on Pre-Exposure Prophylaxis Calls for Immediate Planning to Anticipate Study Results of Potential New HIV Prevention Option

...ions against HIV currently in development," Warren continued. "By mid-2009, more people will be enrolling in PrEP studies than in both HIV vaccine and microbicide efficacy trials combined. Advocates and communities affected by HIV need to understand PrEP and its implications for the AIDS advocacy and global heal...

microbicide in Medical Products

BETADINE® Solution Swabsticks

Description:... BETADINE® Solution Swabsticks are indicated whenever a topical microbicide is applied most conveniently with a swabstick....
Company:Purdue Pharma L.P.

TECHNI-CARE Surgical Scrub

Description:... Topical, Bactericide, microbicide for professional degerming, pre-op and post-op procedures. Advanced technology in skin disinfectants combining quaternary and substituted phenolic act...
Company:Care-Tech Laboratories, Inc.

microbicide in Biological News

New lab test offers better prediction of HIV microbicide safety

July 9, 2009 (BRONX, NY) Scientists at Albert Einstein College of Medicine of Yeshiva University have devised a laboratory test for predicting whether microbicides against HIV are safe for human use. The researchers have also discovered why several supposedly "safe" microbicides made women more ...

Scientists develop a new HIV microbicide -- and a way to mass produce it in plants

In what could be a major pharmaceutical breakthrough, research published online in The FASEB Journal ( http://www.fasebj.org ) describes how scientists from St George's, University of London have devised a one-two punch to stop HIV. First the report describes a new protein that can kill the viru...

UCSF study will test new vaginal microbicide for herpes and HIV

A team of researchers at UCSF is seeking young women to participate in the first U.S. study of the safety of a new a vaginal gel designed to prevent herpes and HIV infection. If it is effective and approved by the U.S. Food and Drug Administration, the gel would be an important weapon in the figh...

Study defines effective microbicide design for HIV/AIDS prevention

Duke University biomedical engineers have developed a computer tool they say could lead to improvements in topical microbicides being developed for women to use to prevent infection by the virus that causes AIDS. Providing women with improved microbicides is a pressing challenge because women no...

Cutting-edge amfAR grants fight HIV/AIDS in the lab and on the phone

...he new Fellowship recipients will examine viral latency and new targets for microbicide and anti-HIV drug development. "HIV does not slow down in a recession,"...viral entry. Such compounds would represent ideal active ingredients in new microbicide products. Social and behavioral - Applying social networking technolo...

UT pathologists believe they have pinpointed Achilles heel of HIV

...t appears to be very effective in killing the HIV virus. The main question now is if this can be applied to developing vaccine and possibly used as a microbicide to prevent sexual transmission," said David C. Montefiori, Ph.D., director of the Laboratory for AIDS Vaccine Research & Development at Duke Universi...

CONRAD receives $28.5M Gates Foundation grant for HIV prevention research

...n has awarded a total of $65 million to CONRAD for microbicide research. The award will support the developm... improved in vitro and small-animal models to test microbicide safety and efficacy, validation of clinical biomarkers and testing of the new microbicide candidates for clinical safety. Despite setba...

New licensing agreement to maximize AIDS drug development

... collaborated for many years on all aspects of our microbicide development programs, and we have a deep respect f... has been involved in the research of nearly every microbicide currently in clinical trials. They are currently managing a second Phase III trial of a microbicide called Ushercell in Uganda and South Africa, Benin...

Anti-HIV drug has potential to prevent transmission in women

...o treat HIV is also safe when applied as a vaginal microbicide gel. Microbicides are designed to prevent the sexu...made by Gilead Sciences. Currently, there is no microbicide available that has been approved for widespread us...ct acceptability study and did not evaluate if the microbicide would be effective in preventing the transmission ...

Vaginal gel may provide a new approach to HIV prevention

...protect the animals against an HIV-like virus. The research suggests that a microbicide using compounds that inhibit the processes by which HIV attaches to and ent...armaceutical company has licensed an anti-HIV compound for development as a microbicide when the class of drugs is so early in development. Women make up nearly...

microbicide in Biological Technology

ImQuest Presentations at CROI Report Significant Advances in Therapeutic and Microbicide Product Development Programs

FREDERICK, Md., Feb. 20 /PRNewswire/ -- ImQuest Life Sciences presented important new results on the continued development of their small molecule pyrimidinedione inhibitors of HIV-1 at the 16th Conference on Retroviruses and Opportunistic Infections held last week in Montreal. Presentations focus...

ImQuest BioSciences and Arisyn Therapeutics Announce Strategic Partnership to Develop Infectious Disease and Cancer Drugs

...ces, Inc. ImQuest BioSciences, a privately held U.S. company located in Frederick, Maryland is a leading provider of anti-infective therapeutic and microbicide development and anti-cancer services to the biotechnology and pharmaceutical industry. ImQuest has broad based capabilities to assist companies with t...

ImQuest Presents Data on the Anti-Hepatitis B Virus Activity of Pyrimidinediones at the 13th ISVHLD Meeting in Washington D.C.

...of infectious disease and cancer. ImQuest BioSciences , also located in Frederick, Maryland, is a leading provider of anti-infective therapeutic and microbicide development services to the biotechnology and pharmaceutical industry. For further information regarding this press release please contact: ...

ImQuest Receives $6.4 M Five Year Award from NIH to Develop Long-Lasting Combination Topical Microbicides To Prevent HIV Transmission

... lasting, safe, and acceptable combination topical microbicide product. ImQuest and a consortium of microbicide r...focus on the development of ImQuest's portfolio of microbicide products and the proposed combination microbicide ...d that the NIH has seen fit to fund this important microbicide development program and we look forward to working...

Leading AIDS Experts Urge Greater Focus on Behavior-Change Programs to Prevent HIV

...ere University in Uganda. "In the 21st century, reducing risky sex and drug use is absolutely essential for slowing HIV, especially since a vaccine or microbicide could take far longer than hoped." Report Identifies Key Elements of Successful Behavior-Change Programs The Working Group report points to divers...

ImQuest Awarded SBIR Grant to Define the Mechanism of Action of Their Lead Anti-HIV Therapeutic Compound IQP-0410

...nt of infectious disease and cancer. ImQuest BioSciences, also located in Frederick, Maryland, is a leading provider of anti-infective therapeutic and microbicide development services to the biotechnology and pharmaceutical industry. Robert W. Buckheit, Jr., Ph.D. EVP, Chief Scientific Officer rbuckheit@i...