New Genetic Technology IDs Virus That Killed Transplant Recipients
...is true of up to 40 percent of the respiratory infections that kill about two million people worldwide each year, he said.
"This new application of metagenomic
pyrosequencing may well aid in the identification of unknown microbial agents that cause human disease," Whitley wrote.
"The real story is the comi...
Recently discovered virus associated with pediatric respiratory tract infection in Germany
...ing culture, antigen tests, and serology. Broad-range molecular systems pioneered by this team including MassTag PCR, GreeneChips and high throughput metagenomic
sequencing, enable pathogen discovery, surveillance and medical diagnostics. Recent application of these technologies led to diagnosis of viral hemorr...
Analysis of Lake Washington microbes shows the power of metagenomic approaches
WALNUT CREEK, CAToday's powerful sequencing machines can rapidly read the genomes of entire communities of microbes, but the challenge is to extract meaningful information from the jumbled reams of data. In a paper appearing in Nature Biotechnology August 17, a collaboration headed by researcher...
DOE JGI sets 'gold standard' for metagenomic data analysis
With the advent of more powerful and economical DNA sequencing technologies, gene discovery and characterization is transitioning from single-organism studies to revealing the potential biotechnology applications embedded in communities of microbial genomes, or metagenomes. The field of metagenomi...
PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information
In the March 3 issue of Nature, Johns Hopkins researchers report that two proteins best known for very different activities actually come together to turn the liver into a sugar-producing factory when food is scarce. Because the liver's production of sugar is a damaging problem in people with diabe...
Reviews of microbial gene language published in special issue of Trends in Microbiology
...P. The application of standards such as the Gene Ontology, and particularly the PAMGO terms, will be essential to make sense of the massive amounts of metagenomic
annotation that will be collected during this project."
Another paper in the series looks at how the Gene Ontology has been used to classify the f...
Genes from tiny marine algae suggest unsuspected avenues for new research
...l biology, we will be able to discover the function of such genes. This will advance our understanding of these organisms and their ecology as well as metagenomic
analyses. It's really basic cell biology, but the implications for doing ecological work are huge."
Figuring out what these genes "do" could also h...
New computational technique allows comparison of whole genomes as easily as whole books
...n encoding text, sounds and images. It may also help in tracing human ancestry and disease demography using whole genome sequences, and in grouping of metagenomic
data - the sequences of genome fragments from many organisms, most of which are unknown species, found in a given environmental niche or body organ.
Human Microbiome Project awards funds for technology development, data analysis and ethical research
...t advances in DNA sequencing technologies have accelerated a process called metagenomic
sequencing. Instead of focusing on the genomes of individual microbes, metagenomic
sequencing analyzes all of the DNA of all of the microbes found within a sa...
DOE JGI extends the capabilities of the Integrated Microbial Genome System
...les that were the subject of recently published studies. These include the metagenomic
and functional analysis a microbial community from Lake Washington in Seatt...em is the most comprehensive and constantly evolving resource for analyzing metagenomic
data, offering an array of valuable analysis tools in conjunction with link...
Surprising discovery from first large-scale analysis of biodiversity and biogeography of viruses
...S, resulting in the discovery of abundant viruses in the human gut (PLoS Biology, 2006) and different variants of dengue viruses. Now, with more viral metagenomic
data accumulated, we are able to summarise the biodiversity and biogeography on a global scale.
Microbialites are organosedimentary structures accr...
DOE JGI releases a new version of its metagenome data management and analysis system
... five additional metagenome datasets generated from microbial community samples that were the subject of recently published studies. These include the metagenomic
and functional analysis of termite hindgut microbiota (Nature 450, 560-565, 22 November 2007) and the single cell genetic analysis of TM7, a rare and ...