Neuronal 'traffic jam' marks early Alzheimer's disease
Early Alzheimer's disease may be precipitated by a "traffic jam" within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers. In mouse models of Alzheimer's disease and in human brain samples from people with the disease, researchers observed a characteristic breakdown in...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characteristic brain plaques are removed.Researchers at Washington University School of Medicine in St. Louisinjected mice with an antibody for a key component of brain plaques,the amyloid beta (Abeta) peptide. In areas of the brain whereantibodies cleared plaque...Ecological destruction fuels emerging diseases
The destruction of habitat by human activity and the extinction of species around the world is more than a looming environmental catastrophe, warns a Canadian zoologist. This ecological damage also endangers human health by turning parasites into "evolutionary land mines." Dr. Daniel (Dan) Brooks, a parasitologist at the University of Toronto, says the decline of global biodiversity is li...Combination therapy boosts effectiveness of telomere-directed cancer cell death
Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...U of M researcher examines newly emerging deadly disease
Researchers at the University of Minnesota have identified a newly emerging illness, named staphylococcal purpura fulminans. The disease begins as a respiratory tract infection, which then is infected by Staphylococcus aureus. The infection then moves to the lungs, making superantigens (bacterial toxins that activate large numbers of T cells), often leading to death due to hypertension and shock....DNA/RNA Aptamer Microarray - Comprehensive Service from LC Sciences
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Description:Physical form: Essentially sulfate-free, powder containing carbohydrate and citrate buffer salts Chem comp: Protein ~ 50% (modified Warburg-Christian)...Anti-S-100 protein, ab heterodimer Monoclonal Antibody, Unconjugated from HyTest Ltd.
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Description:In an effort to help promote genomics-based research with S. aureus, Sigma-Genosys has developed the Staphylococcus aureus ORFmer set that contains PCR primers to amplify all open reading frames (ORFs) in the COL strain1. In addition, primer pairs are included to amplify ORFs that are unique to both the Mu50 and N315 strains of S. aureus. The ORFmer set contains primers to amplify all 2,731 ORFs...Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance
Stratagene We introduce six pairs of control RT-PCR primers that are designed todetect specific human gene transcripts with various expression levels. Theseprimer sets provide insight into whether cDNA synthesis has been effective forall ab...Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase
pfuturbo DNA polymerase for robust, high-fidelity PCRamplification Holly Hogrefe Brad Scott Kirk Nielson ValerieHedden Connie Hansen Janice Cline Frances Bai Jeff Amberg RondaAllen Mark Madden Stratagene an improved version of Pf...Pfu DNA Polymerase as a Hot Start Alternative
Stratagene Cloning Systems, Inc. This article describes the important, novel application of Stratagenes PfuDNA polymerase for minimizing PCR cold start mismatched primer-extensionreactions. These mismatched extension rea...PCR Performance Comparisons Between pfuturbo and Taq DNA Polymerases
pfuturbo DNA polymerase is the superior choice for robusthigh-fidelity PCR amplification Stratagene In this update, we compare the PCR performances of pfuturbo DNApolymerase * ,</...pfuturbo DNA Polymerase: A High-Performance, High-Fidelity Enzyme Ideal for PCR Cloning
A High-Performance, High-Fidelity Enzyme Ideal for PCR Cloning Stratagene was cloned into the PC...PCR emerging as a promising technique for Diagnosing Urinary Tuberculosis
Urinary Tuberculosis is often difficult to diagnose and many a times the diagnosis is made by exclusion. Urine polymerase chain reaction (PCR) is emerging as a promising technique for early diagnosis of Urinary Tuberculosis. The technique involves detection of bacteria by facilitating rapid amplification of small amounts of a genome sequence, Dr Narmada P Gupta told the Millennium Interna...Evidence Links Protein Damage to Neurodegenerative diseases like Parkinson's and Alzheimer's
Neurodegenerative diseases - including Parkinson's, Alzheimer's, Diffuse Lewy body disease, and Multiple System Arophy - are collectively called synucleinopathies. Most commonly they become symptomatic due to a deficiency of a specific neurotransmitter - in the case of Parkinson's it is dopamine. When the neurons that produce these chemicals die or become impaired, which occurs with oxida...Miracle cure for Alzheimer’s around the corner
Alzheimer’s Disease, one of the most common and perhaps the most dreadful kind of Dementia, where there is degeneration of the brain tissue, might at last have the much awaited miracle cure round the corner. A vaccine made headlines sometime ago, as being efficient in reducing plaque formation in mice, which is characteristic of Alzheimer’s. Latest reports say that it also improves mental...Abstain from sex- the latest mantra of American teens
The latest fad in the United States of America is surprisingly abstinence!!!!! Shockingly enough the teen crowd, particularly below 18 years, is taking the buzzword seriously.Last year there were many public abstinence pledges with many millionaire celebrities joining the jing bang. This pledge has been taken seriously, alteast for a certain period of time, according to some analysts who...Clinton's new problem - Is the outgoing American president suffering from skin cancer?
The outgoing U.S. president Bill Clinton will be remembered as one of the most controversial presidents ever. He created history by becoming the first American president in history to be impeached by the House of Representatives. Only because he managed to win at the senate did he save himself and his country further damage. He has been the center of many burning controversies throughout...Meridional Implant (106 Style)
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WNVis a positive single-stranded RNA flavivirus of about 11 kb. It primarily infe...Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
WINNIPEG, Manitoba - (July 11, 2007) Medicure Inc. (TSX:MPH;Amex:MCU), a cardiovascular focused, biopharmaceutical company,today announced that the two-year, follow-up results from theSTRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-ElutingStent Versus Abciximab and Bare Metal Stent In Acute MyocardialInfarct...Samaritan's Alzheimer's Drug Caprospinol Suggests Brain May be Able to Heal From Alzheimer's Disease
Animal Study Confirms Caprospinol's (SP-233) Ability to Clear BrainPlaque and Empower Rat Brain Cells to Recover Memory Function In Vivo 'Proof of Concept' Study Proposes Direct CorrelationBetween Removing Beta Amyloid Plaque and Memory Recovery LAS VEGAS, July 10, 2007 (PRIME NEWSWIRE) -- SamaritanPharmaceuticals Inc. (AMEX:LIV), a developer of innovative drugs,is ple...Molecular Target of Bradmer's Neuradiab Further Validated by Independent Findings
TSX: BMR TORONTO, July 10, 2007 /PRNewswire-FirstCall/ - BradmerPharmaceuticals Inc., a biopharmaceutical company dedicated to thedevelopment and commercialization of cancer therapies, todayannounced that new research published by an independent team inBasel, Switzerland validates tenascin as an important moleculartarget for the development of new treatments for glioblastomamultiforme (G...Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
MALVERN, Pa., June 28, 2007 /PRNewswire-FirstCall/ -- AuxiliumPharmaceuticals, Inc. today announced that Mr. Armando Anido, ChiefExecutive Officer and President, and Mr. Jim Fickenscher, ChiefFinancial Officer, will participate in the 2007 CEUT EmergingGrowth Opportunities Conference to be held July 10 through July 12,2007 at the Mandarin Oriental Hotel in New York City. Mr. Anido issche...