Protein discovery could unlock the secret to better TB treatment
UCL scientists have found a protein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and...Topical treatment shown to inhibit HIV and herpes simplex virus infection
Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina. The study, which was fund...Male circumcision reduces risk of HIV transmission from women to men
The first study to examine the probability ofHIV infection per act of heterosexual sex among a population withmultiple sexual partners has found that uncircumcised men have morethan twice the risk of acquiring HIV than do circumcised men.In the study, published in the Feb. 15 issue of The Journal ofInfectious Diseases, now available online, Jared Baeten and colleaguesfrom the United States...A much-needed shot in the arm for HIV vaccine development
International efforts towards developing avaccine against HIV infection have been given a much-needed boost bythe publication today of the Global HIV/AIDS Vaccine Enterprise'sscientific strategic plan, published online in the freely available,open-access global health journal PLoS Medicine.The Global HIV/AIDS Vaccine Enterprise is an international alliance ofindependent agencies and organiz...GATA: a graphic alignment tool for comparative sequence analysis
Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...Full-Configuration Camera Link NI PCIe-1429 from National Instruments Corporation
Description:The National Instruments PCIe-1429 is the industrys first PCI Express image acquisition board.With the NI PCIe-1429, you now can acquire images at the highest speeds, resolutions, and bit depths available for Camera Link cameras to perform demanding imaging applications such as synchronized data and image acquisition, fault analysis, and advanced motion tracking. In the past, acquiring ima...Bio-Stack Twister II Microplate Handler from BioTek Instruments
Description:The Bio-Stack Twister II Microplate Handler is a high-capacity, plug-and-play bench top automation solution for integrating BioTeks washers, readers and liquid handling systems together with expandable microplate capacity, ultimate flexibility and intuitive and powerful software. Whether you are adding capacity to single devices or linking several modules together to complete a robotic system, th...ELx50 Microplate Strip Washer from BioTek Instruments
Description:The ELx50 is a fast and versatile automated strip washer which can come equipped with our patented Dual-ActionTM 16-channel manifold. This breakthrough design allows for independent control of the dispense and aspiration manifolds for overfill washing and overflow protection in both 96- and 384-well formats. The problem of fitting dispense and aspirate tubes into a much smaller 384-well is solved...Bio-Stack Microplate Stacker from BioTek Instruments
Description:The Bio-Stack is compatible with BioTeks microplate washers, dispensers and detection systems. Speed, ease of use and walkaway automation are guaranteed for any routine microplate process. When used with the ELx405 washer or Fill continuous reagent dispenser, the Bio-Stacks small footprint fits easily in most standard laboratory hoods without the need for a computer....Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice or Rats
Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice orRats Precise and cost-effective micronucleus analysis made easy with theicroFlow Micronucleus Analysis Kit Litron Laboratories, Rochester, NY Mark J. Dycaico<br...Signal Transduction Reporting Systems Using Cis-Acting Enhancer Elements
Stratagene Cloning Systems, Inc. Enhancer elements are the convergent points for many intracellular signaltransduction pathways. For simple, rapid and convenient assessment of the invivo activation of these pathways, Stratagene has d...Fractionating DNA Fragments Generated by Differential Display PCR
Pfizer Central Research, Sandwich, UK. 01304 618482 Differential display PCR (DDPCR) is a widely used technique foridentifying genes differentially expressed between cell types. Application ofDDPCR to allergic disease provides a potential means for elucidating themechanisms involved in allergic...Mammalian Expression Vector for Efficient Cloning of PCR Fragments
Tanya Hosfield Kerstien Padgett Tim Sanchez QuinnLu Stratagene Cloning Systems, Inc. cloningstrategy by introducing a new vector for high-efficiency cloning of PCRfragme...An Assessment of the Eppendorf twin.tec plate performance in PCR* applications
M. Arun Kumar, PhD, and Vincent Prezioso, PhD, Brinkmann BioSystems Laboratory To evaluate the performances of Eppendorf 96-well twin.tec PCR plates, we carried out PCR reactions with twin.tec plates and PCR microplates from another commercial mi...Restriction fragment length polymorphism
sequences) by which they may be dis...Advances in Treatment of Cataracts
Cataracts occur when the eye's lens becomes cloudy and obstructs the passage of light to the retina. These obstructions can lead to vision loss. //Cataract is a major cause of blindness in India. Modern corrective surgery requires implantation of artificial lenses, however these implants often leave patients dependent on eyeglasses. But now, a recent study at Harvard Medical School has sh...Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
It is not high levels of cholesterol but low levels that are making news. Recent reports are indicating that Low levels of Cholesterol maybe linked to depression and violent behavior. A new study shows that men with relatively low cholesterol levels were up to seven times more likely to report symptoms of severe depression. Edward Suarez, PhD from Duke University Medical Center in Durha...Recommendations for Treatment of Blood Pressue
The National Heart, Lung, and Blood Institute (NHLBI) and the National High Blood Pressure Education Program (NHBPEP),USA, have come out with recommendations to treat Hypertension.Control of systolic blood pressure is as important as control of Diastolic blood pressure. This is a crucial message for health care providers, patients, and their families. For many years, the importance of low...Developmental, neurologic problems common in extremely preterm infants
Extremely preterm infants born before 25 weeks' gestation often have severe neurologic and developmental disabilities, researchers report in the August 10th issue of The New EnglandJournal of Medicine.The EPICure Study Group identified 308 children born at the gestational age of 25 weeks or earlier in the UK and Ireland. Of these, 283 were assessed for neurologic function Based on their l...Thyroid hormone treatment hastens recovery after cardiac surgery
Thyroid hormone treatment after surgery requiring heart bypass speeds recovery in children undergoing correction of congenital heart defects, according to a clinical trial published in The Lancet. The effects were greatest in the patients who underwent long and difficult surgeries. Following trauma or surgery or during a critical illness, thyroid hormone concentrations plummet. Ma...Maumenee-Barraquer Vitreous Sweep Spatula - Right
Description:10 mm angled tip with indentation on side and gently curved blade. Round knurled handle with polished finish. Indentation: right side....Maumenee-Barraquer Vitreous Sweep Spatula - Left
Description:10 mm angled tip with indentation on side and gently curved blade. Round knurled handle with polished finish. Indentation: left side....Point of Care Strep Tests Speed Treatment, Lower Costs
Beta-hemolytic group A streptococcus (S. pyogenes) is the most common bacterial agent associated with upper respiratory tract infections. Although it usually involves mild symptoms (such as headache, fever or abdominal pain) if left untreated streptococcal infection can worsen and become life-threatening. Early diagnosis and treatment of group A streptococcal pharyngitis has been shown to red...Rapid HIV Testing Increases Possibility of Treatment
According to a November, 2005 joint press release from UNAIDS (Joint United Nations Programme on HIV/AIDS) and the World Health Organization, the number of people living with HIV globally reached an estimated high of 40.3 million people in 2005, with over 3 million deaths caused by AIDS. The latest data from...Choosing Lab Quality Management Software
Lakeridge Healths large multi-site lab faced challenges with manual document control processes and accreditation management challenges which were exacerbated by staff shortages and growing test volumes. The lab realized that better document control was essential for accreditation compliance and also to enable their laboratorians to more efficiently access and manage do...Optimizing Quality Control Data Management
Automation continues to gain importance in modern clinical laboratories in step with increasing test consolidation, rising demands from clinicians for rapid turnaround times, and an ever-mounting shortage of licensed medical technologists. Ultimately, the laboratories that implement high-quality automation solutions are better equipped to meet these modern demands....Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
NEW YORK, July 12, 2007 /PRNewswire-FirstCall/ -- ImCloneSystems Incorporated and Bristol-Myers Squibb Company todayannounced results from an open-label Phase III study of ERBITUX(R)(Cetuximab) plus a taxane and carboplatin in the first-linetreatment for metastatic non-small cell lung cancer (NSCLC). Thestudy did not meet its primary endpoint of progression-freesurvival (PFS) as assessed...