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melanomas in Medical News

SOX9 renders melanomas sensitive to retinoic acid and stops tumor growth

Melanomas are often resistant to standard cancer therapies such as radiotherapy, chemotherapy, and retinoic acid (RA). Given the lack of available treatments for melanoma, the prognosis for patients is often poor. However, Vincent Hearing and colleagues at the National Cancer Institute at the Nati...

New Research on Genetic Changes in Melanomas and Teens' Use of Indoor Tanning Could Lead to Better Prevention and Treatment Strategies

CHICAGO, July 30 /PRNewswire/ -- Melanoma, the most serious form of skin cancer, accounts for more than 75 percent of all skin cancer deaths. Despite repeated health warnings based on proven science that overexposure to ultraviolet (UV) light is the most preventable cause of all skin cancers, ...

Most lethal melanomas are on scalp and neck

CHAPEL HILL People with scalp or neck melanomas die at nearly twice the rate of people with melanoma elsewhere on the body, including the face or ears, researchers at the University of North Carolina at Chapel Hill have found. The analysis of 51,704 melanoma cases in the U.S. confirms that sur...

Older Men Need to Take Closer Look for Melanomas

If you can't examine your own back, have a loved one take a look, study says MONDAY, April 20 (HealthDay News) -- A new study delivers a lifesaving message to older men about the potentially deadly skin cancer known as melanoma: If you can't examine your own back, have a loved one take...

Larger skin lesions appear more likely to be melanomas

Skin lesions larger than 6 millimeters in diameter appear more likely to be melanomas than smaller lesions, according to a report in the April issue of Archives of Dermatology, one of the JAMA/Archives journals. The findings suggest that the diameter guidelines currently used by dermatologists to ...

Drug Proves Effective in Slowing Melanomas

Riluzole, used to treat Lou Gehrig's disease, inhibits aggressive growth, study finds TUESDAY, April 15 (HealthDay News) -- The drug riluzole, approved in the United States to treat amyotrophic lateral sclerosis (ALS), slows the growth of highly aggressive melanoma skin cancer, accordi...

Gene in Melanomas

Research in mice has drawn a direct link between a human gene and the risk of melanoma, the deadliest form of skin cancer.A team led by Professor Marco Polo from the National Centre of Investigative Oncology in Sweden found that genetically engineered mice with a mutation in the gene, known as Cdk4...

Latest device for identifying Melanomas

A research from Australian company has finalized development of a digital screening device it says will take the guesswork out of diagnosing melanomas, the third most common cancer in Australia. Victor Skladnev, managing director of Polartechnics said that in terms of its ability to diagnose melano...

$1 million grant to RI Hospital M.D. for primary care melanoma screening training program

...etection of melanoma and ultimately reduce the number of melanoma deaths by half. According to the American Cancer Society, an estimated 68,720 new melanomas will be diagnosed in the United States this year. While melanoma accounts for only about five percent of all skin cancer cases, it has by far a much h...

TGen-led team is 1 of 7 selected for $1 million skin-cancer grants

...itt Cancer Center and Research Institute Patrick Hwu, M.D., M.D. Anderson Cancer Center Identification and Validation of Combination Therapies for melanomas Principal Investigators: Team Lead: Michael J. Weber, Ph.D., University of Virginia Levi Garraway, M.D., Ph.D., Dana-Farber Cancer Institute Dan...
melanomas in Medical Technology

Melanoma and Pregnancy: What Every Woman Needs to Know About the Risks, Prognosis

...ver the years, there has been ongoing controversy concerning the effect of hormones on melanoma," said Dr. Driscoll. "Some researchers speculated that melanomas may grow rapidly and spread due to the hormones associated with pregnancy. While we know that hormones may impact other types of cancer, such as breas...

AmpliMed Corporation Announces Promising 1-year Survival Data from Phase I/II Study of Amplimexon(R) in Metastatic Malignant Melanoma

... American Cancer Society, melanoma represents about 5% of all skin cancers, but causes almost 75% of all skin cancer related deaths. Whereas localized melanomas are largely curable by surgery, metastatic melanoma has a poor prognosis and there are few effective treatments. This results in an average survival t...

Kosan Presents Preliminary Phase 2 Data Showing Antitumor Activity of Hsp90 Inhibitor Tanespimycin in Metastatic Melanoma at ASCO

...bits the activity of Hsp90. Hsp90 inhibition results in the degradation of a variety of RAF family proteins, including mutant BRAF. As the majority of melanomas have activation of the BRAF-MAP kinase pathway, it is postulated that tanespimycin interrupts the MAP kinase pathway and may lead to clinically signif...
melanomas in Medical Dictionary

Glomus jugulare tumor

... Glomus tympanicum and Glomus jugulare : Both commonly present as a ... Vascular tissue neoplasm: Glomus tumor (Glomangiosarcoma) Nevi and melanomas (8720-8799) ... Glomus jugulare tumor - Overview, A glomus jugulare tumor is a small, ball-like swelling in ... A person with a glo...
melanomas in Biological News

Molecular differences between early and advanced melanomas could provide new drug targets

The cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found. Understanding this key molecular difference between radial melanomas that spread on t...

The first hyperspectral scanner in Spain

.... In the medical sector, this innovative equipment will be of great use for the detection of cancer cells, enabling doctors to better differentiate melanomas and other skin conditions, for example. In the Construction Sector, the analysis of the chemical properties of cements will be possible, in order t...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

...d in certain cancer cells but not in normal cells. Thirty-five percent of non-small-cell lung cancers have this protein which also is present in some melanomas and head and neck cancers. "The principle is that you can possibly teach a patient's immune system to eliminate cancer cells that express certain...

Fish cancer gene linked to pigment pattern that attracts mates

...ith two partitions. They positioned a male with the faux pattern from which melanomas form on one side, and a male without the pattern on the other. After releas...xually mature at 4.5 months. The ones with the skin cancer gene can develop melanomas at about 7 months and die a few months later. "Melanoma formation cuts ...

As rates rise, researchers find better way to identify melanoma

... more often in metastatic melanomas. IMP-3 was also over-expressed in rare cases of invasive thin melanomas. This is significant because most thin melanomas have a good prognosis, but some act more aggressively and currently there is no accurate way to distinguish between the types of thin lesions. IMP-...

Sun exposure early in life linked to specific skin cancer gene mutation

...ust how these mutations contribute to the cause of melanomas has been a mystery. A new clue comes from scient...0 years old, may specifically increase the risk of melanomas with BRAF gene mutations. A different mutation, on...atellite-base measurements. DNA from the patients' melanomas was then analyzed for mutations. Patients wit...

Rising skin cancer rates are more likely to affect wealthy people, says 12-year review

...n more patients living in wealthier areas and increased levels of malignant melanomas and basal cell carcinomas.” The team looked at data collected by the N...nce didn’t, however, seem to affect squamous cell carcinoma. Malignant melanomas showed the greatest increase over the 12-year study period, with a 48 per c...

Why don't all moles progress to melanoma?

...bout one in 65 Americans born this year will be diagnosed with melanoma at some point during their lifetime. Scientists know that 30 percent of all melanomas begin in a mole. They know that 90 percent of moles contain cancer-causing mutations. What scientists didn't know is how melanocytes stop these mutati...

Speeding discovery of the 'human cancer genome'

...ound. Further study of that common region in mouse melanomas that independently developed their invasive abilit...tly expressed at higher levels in metastatic human melanomas compared to primary melanomas. Drugs aimed at... Chin said. Measurement of Nedd9 levels in primary melanomas might also provide an indication of the cancer's l...

Can dogs smell cancer?

...a by constantly sniffing the skin lesion. Subsequent studies published in major medical journals confirmed the ability of trained dogs to detect both melanomas and bladder cancers. The new study, led by Michael McCulloch of the Pine Street Foundation in San Anselmo, California, and Tadeusz Jezierski of the P...
melanomas in Biological Technology

Melanoma Research Foundation and Seattle Cancer Care Alliance Host Educational Symposium and Reception for Melanoma Patients, Family Members and Healthcare Providers

...melanoma in the United States, making this disease one of the fastest growing cancers in the U.S. and worldwide. Since 1975, the incidence rate of new melanomas has more than doubled-striking people of all ages, all races, all economic levels and both sexes. Currently, there are more new cases of melanoma than...
melanomas in Biological Dictionary

Vessel cell

...eted cell culture vessels , 2.2 through 14 liters total volume ... NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas ... Host cell eNOS but not iNOS contributes to angiogenesis and vessel morphogenesis ... The Hox gene abdominal-A specifies heart cell ...
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