Pro-OpioMelanoCortin (POMC) ELISA Kit from IDS Ltd
Description:Pro-OpioMelanoCortin (POMC) has long been a molecule of fascination, being the prime precursor to a multiplicity of biologically-active peptides such as ACTH, -Lipotrophin (-LPH), -endorphin, Alpha-Melanocyte Stimulating Hormone (a-MSH) and more. It is also a very well-conserved molecule, being found in most vertebrates studied, including those "living fossils", the lungfish. The IDS POMC ELISA m...Inhibition of morphine tolerance by spinal melanocortin receptor blockade
Recent research suggests that the melanocortin system is an important component influencing the changes in the spinal neuronal plasticity observed after chronic morphine administration//. The chronic use of morphine is accompanied by the development of morphine tolerance, which is one of the major problems associated with opiate treatment. Possible modulation of opioid effects by melanoc...