mediastinal

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

...luded in calculations of total cumulative dose Cardiac toxicity may also occur at lower cumulative doses (400 mg/m2) in patients with prior mediastinal irradiation or who are receiving concurrent cyclophosphamide therapy Acute infusion-related reactions including, but not limited t...

NOSCAR announces 2008 NOTES Research Award winners

...dy with Histopathologic Evaluation of Cystotomy Healing Georg O. Spaun, MD, Legacy Health System, Clackamas, OR The Role of Flexible Endoscopy in mediastinal Dissection for Esophageal Surgery Thadeus Trus, MD, University of Rochester, Rochester, NY The NOSCAR Delphi Project: Towards a Research Agenda in...

What should we do when esophageal perforation occurs?

...iastinum, and deep subcutaneous collection suggestive of cervical posterior mediastinal collection. The patient was managed surgically through both an endoscopic a...aused by a foreign body is rare, but can cause potentially life threatening mediastinal complications. CT-scanning enables accurate and timely diagnosis and provid...

Less invasive methods may provide accurate means to determine lung cancer stage

...ecommends invasive staging with tissue confirmation of suspected metastatic mediastinal [center part of the thoracic cavity] lymph nodes. Mediastinoscopy or thorac... EUS plus EBUS also had higher sensitivity for detecting lymph nodes in any mediastinal location and for patients without lymph node enlargement on chest CT. I...

PET imaging significantly enhances standard imaging in lung cancer staging

...imaging is accurate in differentiating between benign and malignant lung tumours as small as 1 centimetre. PET was also shown to be more effective for mediastinal (lymph nodes in the centre of the chest) staging in non-small cell lung cancer. Nonetheless, confirmation of PET findings by surgical biopsy remains ...

Oncolytics Biotech Inc. reports positive interim results of UK phase Ia/Ib trials

...ths, the target tumour had shrunk 64%, with stable disease continuing in the four non-treated tumours, including a 15% volume reduction in non-treated mediastinal disease that was maintained for more than six months. The squamous skin cancer patient experienced a 50% reduction in the target tumour, as well as s...

Modern Radiation Therapy ups Lung Cancer Survival

...n therapy (SRT), often followed by chemotherapy if the lesion was larger than 3 cm or radiotherapy and chemotherapy if the surgical margin or hilar or mediastinal nodes were positive at the time of operation. The five-year survival outcomes are very high, with 50 to 67 percent of these patients living at least f...

mediastinal in Medical Technology

Human Genome Sciences Announces Positive Results in Second of Two Phase 3 Trials of Albuferon(R) in Chronic Hepatitis C

... of serious and/or severe respiratory, thoracic or mediastinal disorders was 2.5% (11/442) for 900-mcg albinterfe...and serious and/or severe respiratory, thoracic or mediastinal disorders were 3.0% (13/440) for 1200-mcg albinter...mpleted, rates of serious respiratory, thoracic or mediastinal disorders were: 0.7% (5/755) for 900-mcg albinter...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

...lculations of total cumulative dose - Cardiac toxicity may also occur at lower cumulative doses (400 mg/m2) in patients with prior mediastinal irradiation or who are receiving concurrent cyclophosphamide therapy * Acute infusion-related reactions including, but not limited to,...

Two DOXIL(R) Studies to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...lculations of total cumulative dose -- Cardiac toxicity may also occur at lower cumulative doses (400 mg/m2) in patients with prior mediastinal irradiation or who are receiving concurrent cyclophosphamide therapy -- Acute infusion-related reactions including, but not limited to, ...

Twelve DOXIL(R) Clinical Studies to be Presented at American Society of Hematology Annual Meeting

...ed in calculations of total cumulative dose -- Cardiac toxicity may also occur at lower cumulative doses (400 mg/m2) in patients with prior mediastinal irradiation or who are receiving concurrent cyclophosphamide therapy -- Acute infusion-related reactions including, but not limited to, fl...

Caelyx Delays Time to Disease Progression as Maintenance Therapy in Patients with Metastatic Breast Cancer

...diones should be included in calculations of total cumulative dosage. Cardiac toxicity may also occur at lower cumulative doses in patients with prior mediastinal irradiation or who are receiving concurrent cyclophosphamide therapy. DOXIL should be administered to patients with a history of cardiovascular diseas...

mediastinal in Medical Definition

Anterior mediastinal mass

... Anterior mediastinal compartment, also known as anterosuperior compart...cle: thymoma Most common primary anterior mediastinal tumor (20%) in adults but rarely seen in children....oma Secondary most common primary anterior mediastinal mass in adults. Most are seen in the anterior comp...

mediastinal in Medical Dictionary

Mediastinitis

...stinitis . ... Patients with mediastinitis can be critically ill. ... mediastinal fibrosis is the least common,but the most severe,late complication ... Ofte...may show a more detailed view of the mediastinitis . ... Introduction· mediastinal Masses· Mediastinitis · Pleural Effusion· Pleural ... Patients who have sev...

Intracellular

...athways. ... Intracellular variably-sized coccoid forms in breast cancer. ... Intracellular bacteria in Hodgkin's disease and sclerosing mediastinal B-cell ... ... interacting with the intracellular domain of the ... Fe65L2 is able to interact, both in vitro and in vivo, with the intracellul...

Inhalation anthrax

...sually fatal, and even with aggressive antibiotic and ... Home page for all CDC anthrax information. Includes basic information as well as ... mediastinal widening with inhalation anthrax (JAMA 1999:281:1735-1745) ... Inhalation or respiratory anthrax is an infectious disease caused by b...

mediastinal in Biological News

Radiation after surgery doubles survival time for some lung cancer patients

... Patients with lung cancer that has spread to mediastinal lymph nodes ?located between the chest, breastbone...rapy benefited patients whose cancer had spread to mediastinal lymph nodes. At that stage, those who underwent ch... resected non-small cell lung cancer with involved mediastinal lymph nodes in addition to chemotherapy. The data ...

mediastinal in Biological Technology

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...ded in calculations of total cumulative dose Cardiac toxicity may also occur at lower cumulative doses (400 mg/m2) in patients with prior mediastinal irradiation or who are receiving concurrent cyclophosphamide therapy Acute infusion-related reactions including, but not lim...

Human Genome Sciences Announces Albuferon(R) Meets Primary Endpoint in Phase 3 Trial in Chronic Hepatitis C

...r peginterferon alfa-2a; and severe and/or serious respiratory, thoracic or mediastinal disorders were 1.0% (3/313) for 900-mcg albinterferon alfa-2b, vs. 1.3% (4/...ron alfa-2a treatment group; severe and/or serious respiratory, thoracic or mediastinal disorders were 1.6% (5/310) in the treatment group originally randomized to...

Oncolytics Biotech Inc. Announces 2007 Third Quarter Results

...ths, the target tumour had shrunk 64%, with stable disease continuing in the four non-treated tumours, including a 15% volume reduction in non-treated mediastinal disease that was maintained for more than six months. The squamous skin cancer patient experienced a 50% reduction in the target tumour, as well as st...

Oncolytics Biotech Inc. Reports Positive Interim Results of U.K. Phase Ia/Ib Combination REOLYSIN(R) and Radiation Clinical Trial

...ths, the target tumour had shrunk 64%, with stable disease continuing in the four non-treated tumours, including a 15% volume reduction in non-treated mediastinal disease that was maintained for more than six months. The squamous skin cancer patient experienced a 50% reduction in the target tumour, as well as st...