Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer
An international team of Mayo Clinic-led researchers is first to devise a system that consistently converts the measles virus into a therapeutic killer that hunts down and destroys cancer cells -- and cancer cells only. Their research findings appear as an advanced electronic article of Nature Biotechnology. The researchers harnessed the viral trait for attacking and commandeering cells,...Measles Deaths Worldwide Drop By Nearly 40% Over Five Years
The World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) today announced that countries are on target to halve deaths from measles, a leading vaccine-preventable killer, by the end of this year. Global measles deaths have plummeted by 39%, from 873 000 in 1999 to an estimated 530 000 in 2003. The largest reduction occurred in Africa, the region with the highest...New study shows measles immunization may prevent fatal brain infection
A new study has found wild-type measles virus in tissues from patients who died of a fatal brain infection, providing evidence against the notion that the strain of virus in the measles vaccine caused the infection. The study, in the November 15 issue of The Journal of Infectious Diseases, now available online, also concludes that vaccination against measles could prevent many more cases of the...Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer
Mayo Clinic Cancer Center has opened a new clinical study using a vaccine strain of the measles virus to attack recurrent glioblastoma multiforme, a largely untreatable brain tumor. This is the second of several pending molecular medicine studies in patients using measles to kill cancer. "We are looking at better ways to treat some of the most lethal cancers," says Eva Galanis, M.D., onco...Investigating the measles virus as a tool to kill multiple myeloma
Mayo Clinic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow that currently has no cure. This is the third of a series of molecular medicine studies in patients testing the potential of measles to kill cancer. “This is the beginning of a long but exciting process,?says Angela Dispenzieri, M.D.,...Measles IgM ELISA Kit, Single from Bio-Quant Inc.
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Replication of human immunodeficiency virus (HIV) is briefly suppressed during acute measles. A study of HIV-infected children found that HIV levels in the blood// were significantly lower while having measles compared to HIV-infected children who did not have measles. "We were surprised by these findings, because we expected to see HIV replication increase, not decrease with measles,...Drop in global deaths from measles
The U.S. Centers for Disease Control and Prevention has reported a global fall in the worldwide death toll from measles. Measeles is a contagious disease and is the fifth leading cause of death for children under the age of five.This has largely been possible due to improved vaccination programs in Latin America and southern Africa. Measles has been virtually wiped out in the industrialized count...Measles Risk in Transplant Patients
People with a compromised immune system who have undergone organ transplantation could be at a high risk of measles if they don’t receive the measles, mumps and rubella vaccine in a timely manner.// Completion of MMR vaccination in southeast London is among the lowest in the United Kingdom. Just over 60 percent of children aged 2 years received a first dose of the vaccine by March 2003...Drop in Worldwide Measles deaths by 40%
There is some good news this week from the World Health Organization (WHO) and the United Nations Children's Fund (UNICEF).// They announced that there is almost a 50% drop of measles death in the last five years worldwide. This is attributed to the successful vaccination programme being undertaken in developing countries. Measles is a vaccine-preventable condition. Global measles deaths have...