Ancient immune defense mechanism is no match for HIV-1
Researchers have discovered that mammalian cells infected with HIV-1 engage a primitive defense mechanism that was previously observed only in plants and invertebrates. The research also reveals exactly how HIV-1 successfully thwarts this rare form of immunity in vertebrate cells. However, elucidation of the mechanism HIV-1 uses to protect itself provides some critical insight into a potential vu...Multiple genes permit closely related fish species to mix and match their color vision
Vision, like other biological attributes, is shaped by evolution through environmental pressures and demands, and even closely-related species that are in other ways very similar might respond to their particular environments by interpreting the visual world slightly differently, using photoreceptors that are attuned to particular wavelengths of light. By studying a special group of closely-relat...Cells use mix-and-match approach to tailor regulation of genes
Scientists eager to help develop a new generation of pharmaceuticals are studying cellular proteins called transcription factors, which bind to upstream sequences of genes to turn the expression of those genes on or off. Some pharmaceutical companies are also hoping to develop drugs that selectively block the binding of transcription factors as a way to short-circuit the harmful effects of diseas...Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
In one of the most ambitious spinoffs of the human genome project, researchers at Dana-Farber Cancer Institute, Children's Hospital Boston, the Broad Institute of Harvard and MIT, and other collaborating centers have unveiled a new, systematic approach to drug discovery that matches diseases with potential treatments using a universal language based on cells' distinctive gene activity profiles, o...Researchers create genetically matched embryonic stem cells for transplantation
Researchers at Children's Hospital Boston report a new and efficient strategy, using eggs alone, for creating mouse embryonic stem cells that can be transplanted without the risk of rejection because the cells are compatible with the recipient's immune system. The findings will be published online in the journal Science on December 14. Though done in mice, the work establishes the principl...BacterioMatch II Two-Hybrid System Vector Kit from Stratagene
Description:...RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes
Stratagene Cloning Systems from the cDNAsequences of mismatch repair genes. These genes code for specialized proteinsthat participate in correcting areas of base mispairing in DNA. We have...Optimizing pfuturbo DNA Polymerase Amplification Reactions with Perfect Match PCR Enhancer
Optimizing pfuturbo DNA Polymerase Amplification Reactions withPerfect Match Stratagene Certain PCR amplification systems produce multiple pro...Matched siRNAs and Assays: Ambion + Applied Biosystems = RNAi Success
Ambion and Applied Biosystems have joined forces to provide a complete convenient, solution for performing gene silencing experiments and validating the results by real-time RT-PCR. Ambion's Validated and Pre-designed siRNAs eliminate the guesswork--and the tedious labwork--associated with si...Tech Council online feature will help match job seekers to skills needed
JobSightUSA helps companies that are considering locating or expanding in Wisconsin to quickly find and hi...Online matchmaking comes to the boardroom
Di...Age Matters in Kidney Matching
Over the years kidney transplantation has come a long way. The number of successfully transplanted kidneys has been able to help more and more people lead a normal lifestyle. //However, a recent study looking into the issue, “If Age matters when matching donor and recipient kidneys,” gave not only the researchers a whole new perspective but also the transplant community. Researchers fr...Cricket Match Lands Mother and Child in ICU after Lathi Charge
Chandigarh: A nine-year-old girl and her mother, injured in a lathi charge during the second one-day international (ODI) between India and England in Faridabad, a satellite town of Delhi, are in the intensive care unit (ICU) of a hospital. // The little girl, Vidhi, had a broken collarbone and a broken wrist and her condition is being closely monitored by doctors. They said Vidhi had s...'Mix and match' of proteins may have a significant role in immunity
Proteins appear to transform more often than biologists once thought. Cutting and rearrangement of the components of these molecules into new structures is carried out by// the human cells. The immune system of the body may be enhanced by this mechanism. This method could also help researchers understand better how the immune system recognizes the infected cells that need to be attacked...Partial-match cell transplants for kids with resistant leukemia
Children with most resistant leukemia can be treated with a superior method of blood stem cell transplantations, when regular treatment fails, as showed by the clinicians at the St. Jude Children's Research Hospital. // The St. Jude technique allows blood stem cells to come from parents or unmatched adult siblings; and it avoids the aggressive, toxic treatments that usually must accom...Researchers Create Genetically-Matched Embryonic Stem Cells for Transplantation
Researchers at Children’s Hospital Boston report a new and efficient strategy, using eggs alone, for creating mouse embryonic stem cells that can be transplanted// without the risk of rejection because the cells are compatible with the recipient’s immune system. Though done in mice, the work establishes the principle of using unfertilized eggs as a source of customized embryonic stem c...AcuMatch P-Series Press-Fit Femoral Stems
Description:A cementless femoral stem that promotes bone in-growth and reduces thigh pain....Acumatch M-Series System - Straight Stem
Description:The AcuMatch M-Series modular femoral stem is a unique, innovative three-piece modular stem designed to address even the most complicated of clinical indications....