Markers

Biomarkers isolated from saliva successfully predict oral and breast cancer

Screening for breast cancer and the early detection of other tumors one day may be as simple as spitting into a collection tube or cup, according to recent studies by UCLA researchers. In one early study based on a risk model, presented here at the 96th Annual Meeting of the American Association for Cancer Research, the UCLA scientists reported that genetic "biomarkers" isolated in saliva...

Measurement Challenges In Detecting Cancer Biomarkers

Effective control of sexually transmitted diseases (STDs) requires treatment of the sexual partners of infected patients. A new study shows that providing infected men with antibiotics to give their partners is more effective than traditional means of contacting and treating the partners, according to an article in the Sept. 1 issue of Clinical Infectious Diseases, now available online. Men with...

New markers of climate change

A new way to monitor the effects of climate change on rainforests is being investigated at Cambridge University. Researchers are using biomarkers in the shape of epiphytes ('air-plants' which grow on other plants) to find out how their photosynthesis and water evaporation have been affected by climate change over the last 50 years. Using types of epiphytes known as bromeliads, Monica Mejia...

U-M scientists discover identifying markers for primitive blood-forming stem cells

Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood. By reading the bar code, scientists can separate stem cells from their more advanced descen...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

Cancer researchers are working toward a future in which each patient's tumor will act like a crystal ball, revealing how oncologists should treat the cancer to obtain the best outcome. Currently, physicians cannot predict which patients with prostate cancer should receive extra therapy after surgery - or whether some of these patients have an indolent disease that does not even require su...

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Markers at Biology Products

Strep•Tag^® II Perfect Protein™ Markers, 16–100 kDa, Lyophilized from Novagen

Description:These protein size markers are a mixture of Strep•Tag® II fusion proteins ranging from 16 to 100 kDa. The markers provide precise size references for proteins on SDS-polyacrylamide gels after staining with Coomassie blue. Because each of the proteins contains the Strep•Tag II sequence, the markers can also be detected by the Strep•Tag II Monoclonal Antibody in Western blots. Th...
Company:Novagen

High Molecular Weight DNA Markers from Invitrogen

Description:High Molecular Weight DNA Markers are suitable for sizing linear double-stranded DNA from 9 to 48 kb on low-percentage agarose gels. The 13 bands consist of 8.3- to 48.5-kb fragments generated from restriction endonuclease digests of Lambda DNA (cIind1ts857 Sam7). Ethidium bromide staining causes the four bands identified by an asterisk (8271 bp 8612 bp 12220 bp and 19399 bp) to show greater inte...
Company:Invitrogen

[14C] Methylated Protein Molecular Weight Markers from GE Healthcare, formerly Amersham Biosciences

Description:[14C] Methylated Protein Molecular Weight Markers, 37 kBq, 1 uCi. Carbon-14 radiolabelled marker proteins enable molecular weight determination of the sample on Western blots.The Rainbow-labeled version also allows visual monitoring of band migration in the gel and on the blot.The specific activity of the [14C] version without Rainbow-labeling is 0.37-3.7 MBq/mg (10-100 uCi/mg) or 185 kBq/ml (5 u...
Company:GE Healthcare, formerly Amersham Biosciences

Markers at Biology Technology

Mammalian Expression Vectors with Interchangeable Selectable Markers

Site-specific recombinase-based vector system Stratagene system of eukaryotic expression vectors offers unparalleled convenience. The drug-resistance genes of these vectors can be exchanged without subcloning. Through site-specific recombination, hygromycin, puromycin,...

MicroRNA Profiling by Array Analysis Reveals Critical BioMarkers

Jaclyn Shingara, Kerri Keiger, Ila Wolf, Jeffrey Shelton, Emmanuel Labourier, and David Brown R&D Division, Ambion, Inc. MicroRNAs (miRNAs) are small, siRNA-like molecules, encoded in the genomes of plants and animals,...

Rapidly Prepare Probes and Markers for Small RNA Analysis

Ideal for analyzing miRNA, siRNA, and other small RNAs Prepare high specific activity RNA or DNA probes Contains reagents to prepare Decade Markers and single-base </B...

siRNA Expression Vectors with Selectable Markers

siRNA expression vectors are now available, each with an antibiotic resistance gene to facilitate selection in mammalian cultured cells. These new vectors are ideal for the long-term study of gene specific kno...

Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma

As the study of protein biomarkers increases in importance, extensive lists of candidate markers are being developed based on protein pathway information and discovery-based proteomics experiments. Even larger numbers of candidate genomic markers exist from DNA transcriptional profiling based on microarray-based gene expressio...

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Markers at Medicine News

Scientific markers of aging described

According to researchers, low body temperature, low insulin and high levels of a specific hormone seem to be linked to a slowdown of the aging process. It is now well known that calorie restriction// increases the lifespan of animals. Now researchers at the National Institute of Aging have some new clues about slowing down the aging process. They compared a group of 500 healthy men, taking part i...

Biochemical Markers Might Help Predict Heart Problems

Damage to the heart is one of the most worrisome long-term side effects of high-dose chemotherapy, say specialists. Hence they feel the // need to identify biochemical markers that might indicate which patients are at greatest risk and how severe their heart disease might be. Troponin I is a protein present only in heart cells. TNI blood concentration is a well-established marker of hea...

Molecular markers for early diagnosis of breast and ovarian cancer

Scientists from Ludwig Institute of Cancer Research and Lviv Regional Oncology center//, Ukraine has developed a new simple and affordable blood test for early detection of breast and ovarian cancer. However, they did not find the proteins in women without cancer. "Attempts to find a single reliable early protein, or 'marker', for breast or ovarian cancer diagnosis have not been very s...

Elevated Insulin Levels To Influence Levels Of Inflammatory Markers

Increase in the levels of insulin can raise the level of inflammatory makers that influence the Alzheimer’s’ Disease. The study is being published by Archives of Neurology. Conditions of insulin resistance and hyper-insulinemia are associated with elevated levels //of inflammatory markers and increase the risk for Alzheimer disease (AD). Inflammation has been proposed as a key pathogen...

Fluorescent markers to distinguish Trypanosoma brucei strains causing Sleeping Sickness

Multiple-genotype infections are increasingly recognized as important factors in disease evolution, parasite transmission dynamics, and the evolution of drug resistance. However, the distinction of co-infecting site genotypes and the tracking of their dynamics have been // ficult with traditional methods based on various genotyping techniques, leaving most questions unaddressed. Trypan...

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Markers at Medicine Products

Surgical Markers

Description:An Ultra-Fine point marker for the surgeons exacting requirements. A Universal point that contains a fine to broad line marking system and a point which allows surgeons to angle the marker to their requirements. A Ruler, an optional convenience that is plastic, which means it will not tear or smear upon contact with liquids. The ink is gentian violet and stands up to scrubs....
Company:Accu-line Products, Inc.

TLS Surgical Markers

Description:TLS Surgical Markers allows the surgeon to effectively diagram incision sites with a scrub-resistant, gentian violet ink. All TLS Surgical Markers are provided sterile, with a ruler and are individually packaged in peel pouches. Micro tip marker for fine line intricate marking, blue barrel....
Company:Porex Surgical Products Group

SQUEEZE-MARK Surgical Markers

Description:Squeeze-mark Surgical Markers have a unique squeezable barrel that provides a continuous flow for writing over wet prep solutions. Micro tip for fine-line intricate marking. Markers with optional rulers and sterile labels are also available. They are provided sterile, packaged individually in peel pouches. Squeeze-mark, MicroTip with Ruler & Labels....
Company:Porex Surgical Products Group

CIC (C1-q) EIA Auto-Immune Markers 001-EK-CIC Circulating Immune Complexes

Description:Circulating Immune Complexes from patient serum or plasma, standards and controls are incubated with human C1q absorbed onto microtiter wells. After a washing step, an alkaline phosphatase labeled conjugate is added, which binds to the Fc region of human IgG. After another washing step, the enzyme substrate is pipetted followed by a stopping step. The absorption is measured at 405 nm....
Company:ALPCO Diagnostics

GBM -Ab EIA Auto-Immune Markers 013-GBM-96 Glomerular Basement Membrane

Description:GBM -Ab EIA Auto-Immune Markers 013-GBM-96 Glomerular Basement Membrane...
Company:ALPCO Diagnostics

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Markers at Medicine Technology

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

CHICAGO--(BUSINESS WIRE)--Jun 25, 2007 - New data from aninvestigational study released at the American Diabetes Association(ADA) 67th Annual Scientific Sessions showed that initialcombination therapy with Januvia(TM) (sitagliptin) and metformindemonstrated significant improvement in markers of beta cellfunction in patients with type 2 diabetes. Pancreatic islet betacell function determines...

First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes

-- Additional Findings Reported on Glucose Homeostasis Effects inNormal and Diabetic Rats -- CHICAGO, June 25, 2007 /PRNewswire-FirstCall/ -- In a 14-day,Phase IIa study of the safety profile of multiple doses of theinvestigational compound dapagliflozin, a selective inhibitor ofthe Sodium-Glucose Transporter 2 (SGLT2) administered alone orconcomitantly with metformin in subjects with Typ...

Pharmacyclics Identifies Functional Biomarkers for its Novel HDAC Inhibitor and Demonstrates Preclinical Anti-Tumor Activity with Bruton's Tyrosine Kinase Inhibitors

SUNNYVALE, Calif. and LOS ANGELES, April 18, 2007/PRNewswire-FirstCall/ -- Pharmacyclics, Inc. today announced datafrom two preclinical studies, one identifying a functionalbiomarker for its novel histone deacetylase (HDAC) inhibitor andanother demonstrating preclinical anti-tumor activity with itsBruton's tyrosine kinase (BTK) inhibitor compounds. The data werepresented at the American...

Millennium Discovers Biomarkers Potentially Predictive of Response to Velcade (Bortezomib) for Injection

- Findings Published in Blood Highlight Millennium Leadership inPersonalized Medicine and Could Strengthen the Role of VELCADE asFoundation of Therapy in Broad Range of Multiple Myeloma Patients - CAMBRIDGE, Mass., April 17, 2007 /PRNewswire-FirstCall/ --Findings published in the April 15th issue of Blood show that ateam of researchers led by Millennium Pharmaceuticals, Inc. hasdiscovered...

Markers at Medicine Definition

Surrogate markers

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