Biomarkers isolated from saliva successfully predict oral and breast cancer
Screening for breast cancer and the early detection of other tumors one day may be as simple as spitting into a collection tube or cup, according to recent studies by UCLA researchers. In one early study based on a risk model, presented here at the 96th Annual Meeting of the American Association for Cancer Research, the UCLA scientists reported that genetic "biomarkers" isolated in saliva...UCLA cancer researchers shake loose hidden biomarker
Using a common chemotherapy agent, researchers at UCLA's Jonsson Cancer Center and the Department of Pathology and Laboratory Medicine found a way to move an important biomarker expressed in prostate cancer, shaking it loose from one location in a cell ?where it could not be accessed by blood ?to another, easier to target area. The discovery, outlined in the cover article of May 11 editio...Measurement Challenges In Detecting Cancer Biomarkers
Effective control of sexually transmitted diseases (STDs) requires treatment of the sexual partners of infected patients. A new study shows that providing infected men with antibiotics to give their partners is more effective than traditional means of contacting and treating the partners, according to an article in the Sept. 1 issue of Clinical Infectious Diseases, now available online. Men with...U-M scientists discover identifying markers for primitive blood-forming stem cells
Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood. By reading the bar code, scientists can separate stem cells from their more advanced descen...Serum Biomarker Chip from Whatman, Inc
Description:The first high-density serum biomarker chip to profile the relative abundance of cancer serum proteins. An antibody chip containing 120 human cancer serum biomarker-specific antibodies. A research tool that enables biomarker discovery scientists to study panels of biomarkers related to early detection, benefits of therapy and the likelihood of recurrence of cancer. Familiar gene expression chip f...Mouse Anti-Quail cell marker Antibody, Unconjugated from Developmental Studies Hybridoma Bank
Description:QCPN...2-D MARKER from Pierce Biotechnology, Inc.
Description:The new Pierce ready-to-use 2-D gel marker mix was designed specifically to aid the proteome analyst. This 2-D gel marker mix contains a complement of seven reduced and denatured proteins that offer important features of value to those who use markers to assess 2-D system performance or estimate pI and molecular weight values of proteins undergoing 2-D separation and analysis. A uniqu...Strep•Tag® II Perfect Protein™ Markers, 16–100 kDa, Lyophilized from Novagen
Description:These protein size markers are a mixture of Strep•Tag® II fusion proteins ranging from 16 to 100 kDa. The markers provide precise size references for proteins on SDS-polyacrylamide gels after staining with Coomassie blue. Because each of the proteins contains the Strep•Tag II sequence, the markers can also be detected by the Strep•Tag II Monoclonal Antibody in Western blots. Th...dsRNA Marker from Abnova Corporation
Description:The dsRNA Marker consists of ten double-stranded RNAs, 10, 20, 30, 50, 100, 200, 300, 400, 500 and 1,000 base pairs. The dsRNA Marker is an ideal size marker for determinating sizes of double-stranded RNAs. A twenty bp RNA band including in the dsRNA Marker is adjusted to approximately 25 ng/µl in concentration. The dsRNA Marker is manufactured for non-denaturing polyacrylamide gel electrop...Mammalian Expression Vectors with Interchangeable Selectable Markers
Site-specific recombinase-based vector system Stratagene system of eukaryotic expression vectors offers unparalleled convenience. The drug-resistance genes of these vectors can be exchanged without subcloning. Through site-specific recombination, hygromycin, puromycin,...Quantitation of the Protein MIA as a Marker for Chondrocytes in Research Samples
MIA (Melanoma Inhibitory Activity) was cloned as asecreted protein from human melanoma cell lines [1]. MIAis expressed in and secreted from malignant melanomasand chondrocytes [2, 3]. As MIA expression in chondrocytesis dependent on the differentiation status of the cel...MicroRNA Profiling by Array Analysis Reveals Critical BioMarkers
Jaclyn Shingara, Kerri Keiger, Ila Wolf, Jeffrey Shelton, Emmanuel Labourier, and David Brown R&D Division, Ambion, Inc. MicroRNAs (miRNAs) are small, siRNA-like molecules, encoded in the genomes of plants and animals,...Rapidly Prepare Probes and Markers for Small RNA Analysis
Ideal for analyzing miRNA, siRNA, and other small RNAs Prepare high specific activity RNA or DNA probes Contains reagents to prepare Decade Markers and single-base </B...siRNA Expression Vectors with Selectable Markers
siRNA expression vectors are now available, each with an antibiotic resistance gene to facilitate selection in mammalian cultured cells. These new vectors are ideal for the long-term study of gene specific kno...New diagnostic marker for prostate cancer
Researchers of the University of Michigan, have found a gene which acts as a specific diagnostic marker for prostate cancer. Using a technique called DNA microarray analysis, which allows investigation of the activity of thousands of different genes in tissue samples. //The gene is called a-methylacyl-CoA racemase (AMACR) and it's never before been seen in association with cancer. In...Scientific markers of aging described
According to researchers, low body temperature, low insulin and high levels of a specific hormone seem to be linked to a slowdown of the aging process. It is now well known that calorie restriction// increases the lifespan of animals. Now researchers at the National Institute of Aging have some new clues about slowing down the aging process. They compared a group of 500 healthy men, taking part i...Tumour marker for melanoma found
According to a recent study it is observed that a molecular marker is linked to prognosis in malignant melanoma. In cancer research today, there is increasing emphasis on looking for molecules// specific to that cancer which might aid in monitoring the progression of the disease. Scientists at New York University now report on a molecular marker called HDM2 which appears to be important in tracki...Osteoporosis and kidney stones gene marker identified
A new study by researchers at the University of Texas has found a gene mutation in people with a family history of kidney stones, which makes them absorb too much calcium. They reported on six gene mutations which increase the risk of kidney stones, because they cause too much calcium absorption - a condition known as absorptive hypercalciuria (AH). They also added that people with kidney stones...Lindstrom Lasik Spatula and Marker
Description:This instrument marks the cornea for centration of the flap and provides a spatula for flap management in primary and enhancement cases. The corneal marker has a pararadial mark that is used to ensure proper alignment of the flap after treatment. The spatula may be used to atraumatically retract the flap and to flood it back into place following laser treatment. The chisel shaped end helps facili...Fechtner Trabeculectomy Marker
Description:Fechtner Trabeculectomy Marker...Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
Clinical guidelines from the disciplines of cardiology and laboratory and emergency medicine have all emphasized the importance of cardiac markers in diagnosing or ruling out acute myocardial infarction. The measurement of cardiac troponins is especially useful in the large fraction of patients presenting with acute coronary syndrome (ACS) who have...