Neuronal 'traffic jam' marks early Alzheimer's disease
Early Alzheimer's disease may be precipitated by a "traffic jam" within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers. In mouse models of Alzheimer's disease and in human brain samples from people with the disease, researchers observed a characteristic breakdown in...FDA Warns Consumers Not to Use Home-Use Diagnostic Kits Marketed by Globus Media
The Food and Drug Administration (FDA) is warning consumers not to use unapproved home-use diagnostic test kits that have been marketed nationwide via the Internet by Globus Media, Montreal, Canada. The use of these products could result in false results that could lead to significant adverse health consequences. The illegal kits are labeled as: Rapid HIV Test Kit. * Rapid Syphilis Te...Biomarkers isolated from saliva successfully predict oral and breast cancer
Screening for breast cancer and the early detection of other tumors one day may be as simple as spitting into a collection tube or cup, according to recent studies by UCLA researchers. In one early study based on a risk model, presented here at the 96th Annual Meeting of the American Association for Cancer Research, the UCLA scientists reported that genetic "biomarkers" isolated in saliva...UCLA cancer researchers shake loose hidden biomarker
Using a common chemotherapy agent, researchers at UCLA's Jonsson Cancer Center and the Department of Pathology and Laboratory Medicine found a way to move an important biomarker expressed in prostate cancer, shaking it loose from one location in a cell ?where it could not be accessed by blood ?to another, easier to target area. The discovery, outlined in the cover article of May 11 editio...Serum Biomarker Chip from Whatman, Inc
Description:The first high-density serum biomarker chip to profile the relative abundance of cancer serum proteins. An antibody chip containing 120 human cancer serum biomarker-specific antibodies. A research tool that enables biomarker discovery scientists to study panels of biomarkers related to early detection, benefits of therapy and the likelihood of recurrence of cancer. Familiar gene expression chip f...MSC.12 class II safety cabinet (Type A1) - CE Marked (120V / 60Hz) from Thermo Scientific
Description:The Jouan MSC series of Class II Biological Safety Cabinets provides comfortable working conditions and certification to the world's highest safety standards. Fully automatic regulation ensures that the cabinets cannot be adjusted out of safe working conditions. Natural lighting, low noise and arm rest ensure safety through comfort....MSC.12 class II safety cabinet (Type A1) - CE Marked (230V / 50Hz) from Thermo Scientific
Description:The Jouan MSC series of Class II Biological Safety Cabinets provides comfortable working conditions and certification to the world's highest safety standards. Fully automatic regulation ensures that the cabinets cannot be adjusted out of safe working conditions. Natural lighting, low noise and arm rest ensure safety through comfort....Mouse Anti-Quail cell marker Antibody, Unconjugated from Developmental Studies Hybridoma Bank
Description:QCPN...HistoMark Biotin-Streptavidin Peroxidase Kit, Rat Primary Antibody from KPL
Description:HistoMark Biotin Streptavidin-HRP Systems provide rapid, precise localization of cell surface and intracellular antigens in frozen or paraffin-embedded tissue, cytospins and touch preparations. These systems also facilitate double or triple labeleing experiments, as detection can be performed simultaneously with primary antibodies of different animal species. Streptavidin demonstrates less non-s...Mammalian Expression Vectors with Interchangeable Selectable Markers
Site-specific recombinase-based vector system Stratagene system of eukaryotic expression vectors offers unparalleled convenience. The drug-resistance genes of these vectors can be exchanged without subcloning. Through site-specific recombination, hygromycin, puromycin,...Corn prices and ethanol: Are the markets flaky - or working as they should?
- About eight percent of the weight of a box of corn flakes is corn. Less than five percent of the price of a box of corn flakes represents the cost of the corn - the rest is transportation, packaging, Super Bowl commercials, little plastic-wrapped toys for your kids, and more. Heck, the price of the box alone probably exceeds the cost of the co...Drug innovation beats marketing, patents and mergers
While Genentech had revenues of $4.6 b...Bone Care marks solid quarter on Hectorol sales jump
Hectorol is a Vitamin D-based drug used to lower abnormally high levels of parathyroid hormone in patients with chronic kidney disease. Gross margins run about 75 percent....Quantitation of the Protein MIA as a Marker for Chondrocytes in Research Samples
MIA (Melanoma Inhibitory Activity) was cloned as asecreted protein from human melanoma cell lines [1]. MIAis expressed in and secreted from malignant melanomasand chondrocytes [2, 3]. As MIA expression in chondrocytesis dependent on the differentiation status of the cel...South Africa Wins landmark case against pharmaceutical giants
South Africa has scored a landmark legal victory over pharmaceutical giants wanting to stop South Africa from importing cheap AIDS drugs. The country with largest number of AIDS patients in the world now wants to secure affordable drugs from around the world to tackle its AIDS epidemic. The Health Ministry of South Africa, published 70 pages of draft legislation that would allow it to s...ZYBAN, The smoking cessation drug marked for its adverse reactions
GlaxoSmithKline's smoking cessation drug Zyban, which is being taken by over 5 million people world wide, is held responsilble for a raise in the suspected adverse reactions due to drug intake in UK. Pharmacovigilance statistics of MCA has shown a raise of about 37% more adverse reactions so called "yellow cards" during the period of January to April 2001 compared to that of last years....India's anti-AIDS drug market engaged in price war
The Indian pharmaceutical companies hope to strike a pot of gold by making cheap anti-AIDS drugs. This has triggered a price war that is likely to escalate in coming days. The large number of AIDS cases has lured many companies to develop anti-AIDS drugs and market it in India and abroad by adapting innovative approaches to pricing. The anti-AIDS drug market, currently dominated...Ranbaxy joins hand with Cipla to co-market ciprofloxacin
Two of the leading pharmaceutical industries, Ranbaxy Laboratories and Cipla announced an alliance to co-market Ranbaxy’s once-a-day formulation of Ciprofloxacin. The formulation had recently received Drug Controller General of India’s (DCGIs) approval for marketing in India. Ciproloxacin is a unique dosage form of the broad-spectrum antibiotic. The domestic market for ciprofloxacin is es...Medicis Pharmaceutical company enters pediatric market
Medicis is the leading independent pharmaceutical company in the United States focusing primarily on the treatment of dermatological conditions. Based in Wilmington, Mass., Ascent is a pharmaceutical company primarily dedicated to the specialty of pediatrics. Medicis Pharmaceutical Corporation and Ascent Pediatrics, Inc. today announced that they have entered into a definitive merger agre...Lindstrom Lasik Spatula and Marker
Description:This instrument marks the cornea for centration of the flap and provides a spatula for flap management in primary and enhancement cases. The corneal marker has a pararadial mark that is used to ensure proper alignment of the flap after treatment. The spatula may be used to atraumatically retract the flap and to flood it back into place following laser treatment. The chisel shaped end helps facili...Surgiscribe Surgical Marking Pens
Description:Gentian violet ink stands up to pre-operative prepping, Millimeter scale ruler printed on the pen's barrel for quick measuring. Flexible, smudge-proof two-sided ruler with both inch and metric scales. Packaged individually in a sterile Tyvek peel pouch....Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
Clinical guidelines from the disciplines of cardiology and laboratory and emergency medicine have all emphasized the importance of cardiac markers in diagnosing or ruling out acute myocardial infarction. The measurement of cardiac troponins is especially useful in the large fraction of patients presenting with acute coronary syndrome (ACS) who have...