malfunctions

Ben-Gurion U. researchers identify how stressed fat tissue malfunctions

BEER-SHEVA, ISRAEL, July 14, 2009 Ben-Gurion University of the Negev (BGU) researchers, in a collaboration with colleagues from the University of Leipzig, Germany, have identified a signaling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-r...

Small Kidney Malfunctions Can Increase The Risk Of Deaths

For patients in hospitals, a small increase in the malfunction of the kidneys can lead to an increased risk of death, especially for patients suffering from acute kidney injury (AKI). Researchers from University of California // San Francisco had reported these results in the latest issue of the Jo...

Lexicon Initiates Phase 2 Clinical Trial of LX2931 in Patients With Rheumatoid Arthritis

...mune system. Inappropriate activation of lymphocytes is often associated with autoimmune diseases, a spectrum of disorders in which the immune system malfunctions and causes the body to attack its own organs, tissues and cells. Rheumatoid arthritis is an autoimmune disorder characterized by stiffness, pain, swe...

St. Jude Scientists Discover a New Mechanism Controlling Neuronal Migration

... Understanding how neurons migrate to their proper place during brain development will offer insights into how malfunctions in the machinery cause epilepsy and mental retardation MEMPHIS, Tenn., July 15 /PRNewswire-USNewswire/ -- The molecular machinery that help...

Inflammation may trigger Alzheimer's disease, Saint Louis University findings suggest

...blood. The blood-brain barrier transporter known as LRP is the pump that removes amyloid beta protein from the brain and into the bloodstream. "LRP malfunctions like a stop light stuck on red, and keeps amyloid beta protein trapped in the brain," said Banks, who also is a staff physician at Veterans Affairs Me...

Sightseeing helicopter crashes in Hawaii decrease following FAA regulations

...e ocean, crashes not involving malfunctions, and nonfatal crashes. Aircraft malfunctions were the most common precipitating factor throughout the study period, occu...ng the 28-year study period. "The persistence of mechanical problems and malfunctions is noteworthy, since they were related to the majority of crashes and not a...

EUROPACE raises remote monitoring profile

... There are many advantages for remote devices. With the current face to face visit approach, physicians commonly first learn about critical device malfunctions and physiological changes when the patient returns to the clinic for a regular scheduled follow-up and manual device interrogation, which only takes p...

Subway Defibrillators Save Lives

... One shock was inadequately delivered by the defibrillator operator. On all other occasions, defibrillators were operated adequately, and no technical malfunctions were observed, despite the strong electromagnetic field caused by the subway operation. Total costs of the Munich subway resuscitation project wer...

Non-Profit Gives $800,000 for Melanoma Research in 2009

...nd treatments ultimately leading to a cure." Approximately seven years ago, the cancer research community began unlocking the underlying genetic malfunctions that occur in cells causing melanoma. Today, researchers are beginning to correlate those discoveries to therapies that may have a meaningful impact ...

The Sudden Cardiac Arrest Association Shoots Straight for the Heart

... essentially a plumbing problem (such as a blocked artery) and SCA is an electrical issue of the heart. SCA occurs when the heart's electrical system malfunctions and the heart goes into a rapid heart beat and then stops beating. Most deaths from sudden cardiac arrest occur with little or no warning. Risk facto...

malfunctions in Medical Technology

Treatment Corrects Severe Insulin Imbalance in Animal Studies

...ide, and reached levels comparable to those in normal, healthy animals. Further studies identified the mechanisms in the hormone signaling system that malfunctions in HI. The next step, says De Leon, is a pilot study now under way to test the effect of exendin-(9-39) in children and adults with congenital HI. I...

Mayo Clinic Clarifies Diagnosis and Treatment for Rare, Serious Blood Vessel Disease of Brain and Spinal Cord

...ith confirmed diagnoses to collect enough data to analyze. -- It carries a high potential for serious complications, even death. A blood vessel that malfunctions may disrupt blood supply and oxygen to the brain or spinal cord, leading to a stroke. While angiography has been the preferred diagnostic technique ...

malfunctions in Medical Dictionary

Respiratory alkalosis

... . ... Respiratory Acidosis .ABNORMAL pH IN THE BODY: ACIDOSIS AND ALKALOSIS : ... Respiratory acidosis or alkalosis is caused by various malfunctions of the lungs. ... Brief and Straightforward Guide: What Is Respiratory Alkalosis ? ... Respiratory alkalosis is a medical condition charact...

Respiratory acidosis

...th acidosis and alkalosis can be of two different types: respiratory and metabolic. Respiratory acidosis or alkalosis is caused by various malfunctions of the ... Overview: Respiratory acidosis occurs when the arterial partial pressure of ... Acute respiratory acidosis can be life threat...

Adrenal glands

... vitamins, herbs, adrenal fatigue disorder natural therapy ... Human adrenal glands secrete vitamin C in ... Adrenal gland disorders malfunctions of the paired adrenal glands . ... The adrenal glands each consist of two morphologically and functionally distinct ... Adrenal disease ...

malfunctions in Biological News

Gene malfunctions cause schizophrenia, depression symptoms in mice

Researchers have demonstrated for the first time that malfunction of a gene that had been associated with schizophrenia and depression does indeed cause symptoms of those disorders. They said their findings in mice offer a possible animal model for developing treatments for schizophrenia and depres...

Structure of protective protein in the eye lens revealed

...ens, αB-crystallin is also very common in the brain and in the heart and muscle tissue. In the eye lens, they counteract diseases like cataracts. malfunctions of the αB-crystallin in tissue cells can give rise to cancer and neurological defects, including Alzheimer's disease. Many research groups ha...

Researchers design first model motor nerve system that's insulated and organized like the human body

.... Nerve malfunctions, called neuropathies, involve a breakdown in the way the brain sends and receives electric signals along nerve cells, leading to malfunctions at the nodes of Ranvier, along with demyelination". Hickman's team has now achieved the first successful model nodes of Ranvier formation on motor ner...

American Chemical Society's Weekly PressPac -- June 3, 2009

...d transcriptional activators. That's because they control a key process known as transcription, in which instructions coded in genes produce proteins. malfunctions in these activators could lead to altered transcription patterns that lead to disease. For example, variations in the tumor suppressor gene p53 are fo...

Biologists discover link between CGG repeats in DNA and neurological disorders

...that the CGG repeats did not respond to the key checkpoint protein called Mrc1 in yeast or claspin in humans. Both proteins work to repair replication malfunctions during the S phase of the cell cycle. Apparently, the unusual structure of CGG repeats acts to escape the cellular checkpoints. As a consequence, chro...

Studies offer guide as protein interaction mapping comes of age

... a comprehensive catalogue known as the interactome. Such information will be critical to understanding the basic mechanics of cellular life, and how malfunctions in these processes contribute to cancer. Unfortunately, the data collected by different teams of researchers has been somewhat inconsistent. One gr...

Researchers continue to find genes for type 1 diabetes

...gy at McGill University in Montreal. Type 1 diabetes, formerly called juvenile diabetes, usually begins in childhood, when the body's immune system malfunctions and destroys insulin-producing beta cells in the pancreas. Without insulin, blood sugar levels run out of control and can impair blood flow and damage...

Study provides insight on a common heart rhythm disorder

...stems to ensure that cellular components don't float around randomly," Mohler said. "Understanding how these cells behave may help us learn how to fix malfunctions that occur when people age or experience common forms of cardiac disease. "Genes that make ankyrin or proteins like it are probably going to be the...

Site used by sodium to control sensitivity of certain potassium ion channels

...mbrane potential is accomplished by potassium flowing out of the cell through potassium channels. If Kir5.1 is linked to sodium reabsorption, then malfunctions of this channel could interfere with the sodium uptake mechanisms from blood vessels through the kidney cells and lead to hypertension. Logothetis and...

Biophysical method may help to recover hearing

...iophysics and bio-mechanics of the natural sensor. They have identified modifications that would enable the remapping of frequencies where the cochlea malfunctions to neighboring intact cochlear areas. This remapping is performed in such a way that no auditory information is lost and the tuning capabilities of th...

malfunctions in Biological Technology

Addiction Treatment Finds Success Treating Brain Deficiencies through the Belly

... effectiveness in counseling and exercise interventions. "Many programs look at nutritional deficits in the brain, but few if any examine the malfunctions in the mechanism that fuels the brain where the deficiency actually starts - in the gut," said Erin McClelland, MS, Executive Director of the cen...

JCI table of contents: April 22, 2008

...people with Alzheimer disease (AD) is the presence of tangles, insoluble twisted fibers that build up inside the nerve cells of the brain resulting in malfunctions in communication between nerves and later in their death. As these tangles are due to abnormal aggregation of the tau protein, AD is classified as a t...

malfunctions in Biological Definition

Brain

...ongenital . Tay-Sachs disease , Fragile X syndrome , Down syndrome , and Tourette syndrome are all linked to genetic or chromosomal errors. malfunctions in the embryonic development of the brain can be caused by genetic factors or by drug use or disease in the mother. Brains in philosophy Some...

Developmental biology

...ch considers the diversity of organismal form in an evolutionary context. The findings of developmental biology can help to understand developmental malfunctions such as chromosomal aberrations , for example, Down syndrome . An understanding of the specialization of cells during embryogenesis may shield inf...

Immunology

...tem in all organisms . It deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders ( autoimmune diseases , hypersensitivities , immune deficiency , allograft rejection); the physica...