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Malfunction in Medical News
Scientists Concerned Over Increasing Malfunction Of Heart Devices
Scientists in the US are worried over the increasing malfunction of heart devices, which they say were directly responsible for 61 deaths between 1990 and 2002. The Food and Drug Administration (FDA) released // a study at a meeting with physicians and heart-device manufacturers recently, which ...American Wins Lawsuit Over Penile Implant Malfunction
An American has won more than $400,000 in a lawsuit over a malfunctioned penile implant that gave him a 10-year erection//. Charles 'Chick' Lennon, 68, of New York city, received the steel and plastic implant in 1996, about two years before Viagra entered the market, reported the online editi...Unlocking the key to human fertility
..."Up until now, Doctors have struggled to understand idiopathic male infertility. Our latest research offers a plausible explanation for why some sperm malfunction or fail to function correctly." If the DNA carried by a sperm cell was unwound and stretched out, it would actually measure more than a metre in l...Photos: Don't Let Them See You Sweat This Summer
...stress, emotion or exercise, but often occurs spontaneously. The precise mechanism that triggers the condition is unclear but appears to be related to malfunction in the sympathetic nervous system -- the part of the autonomic nervous system that regulates "involuntary" bodily functions (those we don't exert cons...Stem Cells Used for 'Biological Pacemaker'
...ho have conduction problems with the electrical signals that govern the heart beat. However, that therapy has several shortcomings, including possible malfunction and the need for repeated replacement of the device's power packs and electrodes," study lead author Dr. Toshinao Takahashi, a research fellow at Chib...C'elle(SM) Featured on ABC Action News in Tampa Bay
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Ben-Gurion U. researchers identify how stressed fat tissue malfunctions
...d Metabolism ( J. Clin. Endocrinol. Metab. 2009; 94:2507-251) "Fat tissue in obesity is dysfunctional, yet, the processes that cause fat tissue to malfunction are poorly understood -- specifically, it is unknown how fat cells 'translate' stresses in obesity into dysfunction," said Dr. Assaf Rudich, senior le...Researchers identify individuals at risk for developing colon cancer
...ts in glycosylation, the process for making mucus, can contribute to tumor development," said Dr. Markowitz. "Knowing how these glycosylation enzymes malfunction and contribute to tumor formation may give us another target that can be potentially used to prevent the development of colon and other cancers. Certa...Sightseeing helicopter crashes in Hawaii decrease following FAA regulations
...ns were the most common precipitating factor throughout the study period, occurring at similar frequencies pre- and post- regulations. The most common malfunction was loss of power, most often caused by improper maintenance. Forty-six tourists and 9 pilots died in 16 fatal crashes during the 28-year study period...Sleep Disorders Linked to Arrhythmias
...thing disorder -- was associated with irregular heartbeats involving the lower chambers of the heart (ventricles). Central sleep apnea -- caused by a malfunction in brain signals that control breathing muscles -- was more strongly associated with irregular heart rhythms in the heart's upper chambers (atria). ...Malfunction in Medical Technology
...tation: When tendons around the mitral valve become loose or break, the valve leaflet becomes floppy, allowing regurgitation. A device to repair this malfunction was invented at Mayo Clinic and helps patients avoid open heart surgery. Instead, a slender device is inserted through the chest to the tip of the hea...
...Hematology in San Francisco, CA. Results from a study examining the ability of an investigational agent to improve endothelial dysfunction, a malfunction in the inner lining of blood vessels, in patients with sickle cell disease will be featured at a press conference on Saturday, December 6, at 9:30 a.m...
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...
...ffering severe head injury. Additionally, the study will further assess the safety of Oxycyte when given by intravenous infusion. Due to a technical malfunction whereby a complete measurement of oxygen levels in the brain of one treated patient was not made, nine patients were treated during this study to meet...
...Hematology in San Francisco, CA. Results from a study examining the ability of an investigational agent to improve endothelial dysfunction, a malfunction in the inner lining of blood vessels, in patients with sickle cell disease will be featured at a press conference on Saturday, December 6, at 9:30 a.m...
St. Jude Finds 'Dancing' Hair Cells Are Key to Humans' Acute Hearing
...ndings will enable better understanding of how hearing loss can result from malfunction of this amplification machinery due to genetic mutation or overdose of drug...the effects on hearing. Those mice showed a hearing defect that indicated a malfunction of somatic motility. While the knockout experiments were strong evidence fo......echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...
NicOx Announces Pfizer Initiates Phase 2 Clinical Development for PF-03187207 in Japan
...ial to have an increased capacity to reduce high IOP relative to currently marketed agents. The development of abnormally high IOP, due to blockage or malfunction of systems controlling the amount of fluid in the eye, is believed to be one of the principal causes of glaucoma. The new Japanese trial is a 28-day...Surgeons Develop Innovative Life-Saving Treatments to Correct Massive Bleeding in Trauma Patients
... Findings from these studies resolved two major concerns about profound hypothermia: the danger that exposure to profound cooling might precipitate a malfunction in the coagulation process and cause bleeding and that it might reduce immune function and lead to infectious complications. "We found that cooling ...Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome
...ms occur more frequently in individuals with Turner syndrome than in the general population, including a heightened incidence of osteoporosis, cardiac malfunction diabetes and an increased risk of ear and hearing disorders. However, there is variability in the degree to which girls with Turner syndrome are affec...Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome
...ms occur more frequently in individuals with Turner syndrome than in the general population, including a heightened incidence of osteoporosis, cardiac malfunction diabetes and an increased risk of ear and hearing disorders. However, there is variability in the degree to which girls with Turner syndrome are affec......ffering severe head injury. Additionally, the study will further assess the safety of Oxycyte when given by intravenous infusion. Due to a technical malfunction whereby a complete measurement of oxygen levels in the brain of one treated patient was not made, nine patients were treated during this study to meet...
Stanford Researchers Find Brain Pathway of Depression in Rats
...sness. Reasoning that the brain is essentially a complex electrical circuit, Deisseroth's team set out to test the theory of whether brain circuitry malfunction could be at the root of depression. To explore the idea in a precise, quantitative way, they needed to develop a visualization tool that was faster an...Malfunction in Medical Products
Brasseler USA 2001 Universal Battery Charger
Description:...ery Packs simultaneously in less than 40 minutes. The Universal Charger is designed to operate on 120 volt AC grounded electrical power. If there is a malfunction in the operation of the Charger, do not remove top cover. Do not attempt to service the Battery Charger, there are no serviceable parts. Return to Bra...Company:Brasseler USA
Brasseler USA™ 2002 Battery Charger
Description:... Battery Packs simultaneously in less than 40 minutes. The 2002 Charger is designed to operate on 120 volt AC grounded electrical power. If there is a malfunction in the operation of the Charger do not remove top cover. Do not attempt to service the Battery Charger, there are no serviceable parts. Return to Bras...Company:Brasseler USA
Vapro Vapor Pressure Osmometer
Features:...ns are selected from a simple menu. The Vapro osmometer is self- calibrating and exceptionally stable. Built in self-diagnostics alert you to any malfunction or procedural error. Statistical functions display average and standard deviation of several samples, and the handy Clean Test monitors thermocoup...Company:Wescor, Inc.
Malfunction in Medical Dictionary
... Sick sinus syndrome , also called sinus node dysfunction, is a group of abnormal heart rhythms (arrhythmias) presumably caused by a malfunction of the sinus node, the heart's primary... Sick sinus syndrome (SSS) is a type of bradycardia in which the sinoatrial (SA) ... Some p...
... Polyneuropathy is a neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously. It may be acute and appear without warning, or chronic and develop gradually over a longer period of time. Many polyneuropathies h...
...me > Dogs Home Page > Lungs, Airways & Chest > Article: Laryngeal Paresis and Paralysis ... Laryngeal paresis (weakness) is caused by malfunction either of ... Definition of paresis from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word g...
...to the kidneys, resulting in retention of nitrogenous and non-nitrogenous waste products... renal failure ( ′rēnəl ′fālyər ) ( medicine ) Severe malfunction of the kidneys, producing ... Chronic failure usually results from long-term kidney diseases. ... Acute kidney failure — Comprehensive ove...
...ic in most patients. ... Hereditary Angioedema : Not an Allergy ... Hereditary angioedema is a genetic disorder due to a deficiency or malfunction of C1 inhibitor. ... If you or someone in your family has hereditary angioedema (HAE), this site can help with tips on managing this rare dise...
... Dysautonomia is a broad term that describes any disease or malfunction of the autonomic nervous system. This includes postural orthostatic tachycardia syndrome (POTS), vasovagal syncope, mitral valve prolapse dys...
..., diabetes, high blood pressure, and obesity. ... rheumatic, symptoms, valvular, ischemic, heart disease in ... coronary heart disease malfunction of the heart caused by blockage of one of the arteries ... 500 000 people die from coronary heart disease each year. ... The coronary ar...
...istinguish colors and have what is called color blindness . ... What Is Color Blindness ? ... Color blindness results from an absence or malfunction of certain color - sensitive cells in the retina. ... Color Blindness - Topic Overview (continued) ... Color Blindness . Contact Lenses—R...
... dominant trait. ... Collagen disease can occur when the body has a malfunction in the immune system. ... Dermatomyositis is a collagen disease that ...he free encyclopedia ... Collagen disease can occur when the body has a malfunction in the immune system. ... (Redirected from Collagen vascular dis...
... Polyneuropathy is a neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously. It may be acute and appear without warning, or chronic and develop gradually over a longer period of time. Many polyneuropathies h...
...me > Dogs Home Page > Lungs, Airways & Chest > Article: Laryngeal Paresis and Paralysis ... Laryngeal paresis (weakness) is caused by malfunction either of ... Definition of paresis from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word g...
...to the kidneys, resulting in retention of nitrogenous and non-nitrogenous waste products... renal failure ( ′rēnəl ′fālyər ) ( medicine ) Severe malfunction of the kidneys, producing ... Chronic failure usually results from long-term kidney diseases. ... Acute kidney failure — Comprehensive ove...
...ic in most patients. ... Hereditary Angioedema : Not an Allergy ... Hereditary angioedema is a genetic disorder due to a deficiency or malfunction of C1 inhibitor. ... If you or someone in your family has hereditary angioedema (HAE), this site can help with tips on managing this rare dise...
... Dysautonomia is a broad term that describes any disease or malfunction of the autonomic nervous system. This includes postural orthostatic tachycardia syndrome (POTS), vasovagal syncope, mitral valve prolapse dys...
..., diabetes, high blood pressure, and obesity. ... rheumatic, symptoms, valvular, ischemic, heart disease in ... coronary heart disease malfunction of the heart caused by blockage of one of the arteries ... 500 000 people die from coronary heart disease each year. ... The coronary ar...
...istinguish colors and have what is called color blindness . ... What Is Color Blindness ? ... Color blindness results from an absence or malfunction of certain color - sensitive cells in the retina. ... Color Blindness - Topic Overview (continued) ... Color Blindness . Contact Lenses—R...
... dominant trait. ... Collagen disease can occur when the body has a malfunction in the immune system. ... Dermatomyositis is a collagen disease that ...he free encyclopedia ... Collagen disease can occur when the body has a malfunction in the immune system. ... (Redirected from Collagen vascular dis...
Malfunction in Biological News
Iron-moving malfunction may underlie neurodegenerative diseases, aging
ANN ARBOR, Mich.---A glitch in the ability to move iron around in cells may underlie a disease known as Type IV mucolipidosis (ML4) and the suite of symptoms---mental retardation, poor vision and diminished motor abilities---that accompany it, new research at the University of Michigan shows. ...How genetic malfunction causes a form of retardation
Researchers have discovered that the genetic malfunction that causes a form of mental retardation called Noonan Syndrome (NS) produces an imbalance in the genesis of two types of cells in the developing embryonic brain. This imbalance, they theorize, could explain how the genetic abnormality gives ...Researchers design first model motor nerve system that's insulated and organized like the human body
... with the model. Other planned experiments will focus on how electrical signals travel through myelinated and unmyelinated nerves to reveal how nerves malfunction as well as for spinal cord injury studies. "Being able to study these fully developed structures means we can really start looking at these things in ...Chemical in blood may explain susceptibility to bladder pain
... cystitis ultimately could affect the way signals are transmitted in the brain. The results, while preliminary, suggest that the disease is not just a malfunction of the bladder, but might instead have origins in the central nervous system, researchers say. Symptoms of interstitial cystitis, known as IC, incl...UT Southwestern researchers probe kidney damage, protection in lupus
... DALLAS April 21, 2009 Kidney damage associated with the autoimmune disease lupus is linked to a malfunction of immune cells that causes them to congregate in and attack the organs, researchers at UT Southwestern Medical Center have discovered in a mouse stud...Malfunction of the respiratory epithelium is a cause of allergy?
... One reason for the development of allergy may be malfunction of the respiratory epithelium, which allows allergens to bind to, enter and travel through the epithelium. Two studies by Finnish research groups on t...Damon Runyon Cancer Research Foundation awards prestigious fellowships to 13 top young investigators
...sensitive fluorescence assays that will allow observation of single molecules of individual enzymes, providing insight into how cellular machinery may malfunction in cancers. William Rodney Hardy, PhD, with his sponsor Michael R. Green, MD, PhD, at the University of Massachusetts Medical School, Worcester, M......n the fly's nervous system", Alexander Borst recapitulates the group's work of the last few years. The scientists' next goal is to ascertain whether a malfunction of the VS network has any direct bearing on the fly's flight skills. "For when it comes down to influencing a certain pattern of behaviour, cells and ...
Sudden cardiac death without recognizable cause
...ardiac ion channels are responsible for at least a third of these deaths. As the ion channels are involved in stimulation and conduction in the heart, malfunction can cause cardiac arrythmias, which may lead to ventricular fibrillation. These primary electrical heart disorders are mostly subject to autosomal...Researchers advance knowledge of little 'nano-machines' in our body
...Canada-U.S. biophysicists will improve the understanding of ion channels, akin to little 'nano-machines' or 'nano-valves' in our body, which when they malfunction can cause genetic illnesses that attack muscles, the central nervous system and the heart. As reported in the current issue of the Proceedings of...Malfunction in Biological Technology
Cryo-Cell Renews Upromise Industry-Exclusive Agreement
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Leading Heart Specialist Joins Duska Therapeutics as Scientific Consultant
...ack, heart failure, stroke and even death. He has also discovered a general mechanism by which protein function is regulated (termed S-nitrosylation), malfunction of which contributes to many human diseases. Dr. Stamler has conducted research on nitric oxide-redox imbalance in the failing heart and cardiovascu...Cryo-Cell International, Inc. Reports Third Quarter 2008 Results
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Cryo-Cell International and EndGenitor Technologies Announce Research Collaboration
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Cryo-Cell International, Inc. Reports Second Quarter 2008 Results
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Stem Cells From Menstrual Blood Show Therapeutic Potential
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Cryo-Cell International, Inc. Reports First Quarter 2008 Results
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ......6-773-7721. About Immune Deficiency Disorders Primary Immune Deficiencies (PIDs) are a group of disorders, usually genetic in nature, that cause a malfunction of the immune system, either in part or in totality, thus preventing the patient from fighting off infections caused by everyday microorganisms. For i...
Cryo-Cell International, Inc. Reports Results for Fiscal 2007
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Cryo-Cell Announces Research Collaboration Agreement with Saneron CCEL Therapeutics, Inc.
...echnological breakthrough or medical breakthrough that would render the Company's business of stem cell preservation obsolete; any material failure or malfunction in our storage facilities; any natural disaster such as a tornado, other disaster (fire) or act of terrorism that adversely affects stored specimens; ...Malfunction in Biological Definition
...
Enzymes and health
Enzymes are essential to living organisms, and a malfunction of even a single enzyme out of approximately 2,000 types present in our b...ad to severe or lethal illness. An example of a disease caused by an enzyme malfunction in humans is phenylketonuria (PKU). The enzyme phenylalanine hydroxylase...
...ions can be subdivided into germline mutations, which can be passed on to progeny and somatic mutations , which (when accidental) often lead to the malfunction or death of a cell and can cause cancer . Mutations introduce new genetic variation, without which evolution cannot proceed. Neutral mutations do...
...ions can be subdivided into germline mutations, which can be passed on to progeny and somatic mutations , which (when accidental) often lead to the malfunction or death of a cell and can cause cancer . Mutations introduce new genetic variation, without which evolution cannot proceed. Neutral mutations do...
Malfunction in Biological Dictionary
...ms, gum disease, the treatment of tooth decay, cavity ... The salivary glands can be affected in various diseases. ... Salivary glands that malfunction or swell can decrease saliva production. ... There are three major pairs of salivary glands in the mouth. ... The major salivary glands con...
... mutation mean? ... point mutation . Etymology: L, punctus, pricked, mutare, to change ... Point mutations are often caused by chemicals or malfunction of DNA replication. ... Another Point mutation that occur within the protein coding region of a gene may ... B. Historically, point mu...
... pituitary is a pea-sized gland that is housed within a bony structure (sella ... Pituitary : The Master Gland ... diagnose pituitary gland malfunction using ... Pituitary Gland Disorders. Hypopituitarism ... In some cases, the pituitary gland's production of a single hormone decreases. ....
... mutation mean? ... point mutation . Etymology: L, punctus, pricked, mutare, to change ... Point mutations are often caused by chemicals or malfunction of DNA replication. ... Another Point mutation that occur within the protein coding region of a gene may ... B. Historically, point mu...
... pituitary is a pea-sized gland that is housed within a bony structure (sella ... Pituitary : The Master Gland ... diagnose pituitary gland malfunction using ... Pituitary Gland Disorders. Hypopituitarism ... In some cases, the pituitary gland's production of a single hormone decreases. ....
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(Date:7/13/2014)... 13, 2014 Advanced boilers are ... least amount of fossil fuels, produce high-capacity power, ... to increased global warming and climate change concerns, ... reduce harmful gas emissions and pollutants coming from ... in the global advance boilers market., The global ...
(Date:7/13/2014)... HealthDay Reporter FRIDAY, July 11, 2014 ... people with diabetes is being developed to measure sugar levels ... Scientists at Brown University in Providence, R.I., created the ... light, metal and a special enzyme that changes color when ... to prick their fingers to draw blood to check their ...
(Date:7/13/2014)... Max International has recently ... be the featured guest at its Charity Exhibition and ... Attendees will learn about Max’s health products and ... basketball games and perform in a 3 point shoot-out. ... and energy-boosting supplements , has recently announced former NBA ...
(Date:7/13/2014)... July 13, 2014 A decreased ability to ... impairment and Alzheimer,s disease, while examinations of the ... protein associated with Alzheimer,s, in the brain, according ... today at the Alzheimer,s Association International Conference 2014 ... the studies, the decreased ability to identify odors ...
(Date:7/13/2014)... ECS is being founded by Seattle ... a special needs child, I have become keenly aware ... contemporary special education resources and evidence-based instruction. Emerald City ... families in the Seattle metro area that are looking ... We welcome the opportunity to serve our community and ...
Breaking Medicine News(10 mins):Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 2Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 3Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 2Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 3Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 2Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 3Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 4Health News:Smell and eye tests show potential to detect Alzheimer's early 2Health News:Smell and eye tests show potential to detect Alzheimer's early 3Health News:Smell and eye tests show potential to detect Alzheimer's early 4Health News:Smell and eye tests show potential to detect Alzheimer's early 5Health News:Smell and eye tests show potential to detect Alzheimer's early 6Health News:Smell and eye tests show potential to detect Alzheimer's early 7Health News:New Private School, Emerald City School, Founded in Downtown Seattle Now Accepting 1st to 6th Grade Students Who Learn Differently 2[0] North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor[0] Saliva Test Might Someday Replace Needle Prick for Diabetics[0] Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event[0] Smell and eye tests show potential to detect Alzheimer's early[0] New Private School, Emerald City School, Founded in Downtown Seattle Now Accepting 1st to 6th Grade Students Who Learn Differently
(Date:7/11/2014)... Evidence exists that cannabinoid receptor type 1 ... Ca2+ influx, and reduce neurotransmitter release. However, ... 1 can increase extracellular Ca2+ influx and ... his team, Tongji Hospital Affiliated to Tongji ... Technology, China used whole cell voltage-clamp and ...
(Date:7/10/2014)... COLORADO SPRINGS, Colo. , June 27, 2014 ... announces that the National Institute of Standards and ... appointed 10 of its academic research and forensic ... Board (FSSB). The Board is an element of ... These AAFS members are among the first appointments ...
(Date:7/10/2014)... 2, 2014 It is a great honor ... appointment of the world-renowned Thoracic and Cardiovascular surgeon, Mark ... Dr. Ginsburg, with over 34 years of experience, ... and Good Samaritan Regional Medical Center. Dr. Ginsburg has ... 1980,s and is considered an expert in the implantation ...
Breaking Biology News(10 mins):Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3Avery Biomedical Devices, Inc. announces the appointment of Mark E Ginsburg, M.D. to its Board of Directors 2| Copyright © 2003-2012 Bio-Medicine. All rights reserved. ABOUT | CONTACT US | DISCLAIMER | PRIVACY POLICY | TERMS AND CONDITIONS |  |