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malformations in Medical News

Adding Folic Acid to Flour Lessens Congenital Malformations

A new study has found that adding folic acid to flour considerably reduces congenital malformations . The study, conducted by Universit Laval's Department of Social and Preventive Medicine, has suggested that the addition of folic acid to flours has led to a 46 percent slump in the incidenc...

Scientists Bioengineer New Teeth in Mice

... of Medicine. "Tooth regeneration could be useful particularly in infant malformations such as cleft lip and palate, and other malformations involving teeth and bone of the oral cavity," Elsas said. Researchers h...

Grant received for eye disorder research

...ket, closing the eyelids and sometimes forcing the eye movement up or down. Duane syndrome usually causes vision problems. It can be accompanied by malformations of the skeleton, eyes, ears, kidneys and nervous system but more commonly occurs in isolation. Most sufferers of the condition are diagnosed by the...

New Scientific Evidence Suggests Humans Resistant to Phthalate Effect on Lab Rodents

...ed no gross testicular structural damage, and no other effects on the reproductive system development, male hormone levels, no hypospadias, which are malformations of the urethra in males, or on their number of germ cells, all the way through to adulthood. The researchers also separately dosed infant male marmose...

Study finds reproductive health effects from low doses of bisphenol-A

...f puberty. Female rats exposed to 50 milligrams per kilogram of body weight (mg/kg) during their first four days of life developed significant ovarian malformations and premature loss of their estrus cycle. "The 50 mg/kg level is important," says lead researcher Dr. Heather Patisaul, "because it is equivalent t...

Joan Massagué wins BBVA Foundation Frontiers of Knowledge Award in Biomedicine

...e inhibitor of cell growth. It is essential for the organism's normal development but, when disrupted, is also implicated in disease processes such as malformations and cancer. Massagu and his group identified the molecular pathway conveying the TGF- signal from the cell membrane to the nucleus rather like decodi...

Newborn weights affected by environmental contaminants

... Montreal, June 15, 2009 Recent epidemiological studies have revealed an increase in the frequency of genital malformations in male newborns (e.g., un-descended testes) and a decrease in male fertility. The role played by the growing presence in our environment of conta...

Off-label morning sickness drug deemed safe for fetuses -- Ben-Gurion U. researchers

...etoclopramide during the first trimester of pregnancy of the 81,703 infants born to mothers during the study period. The rate of major congenital malformations identified in the group that was exposed to metoclopramide during the first trimester was 5.3 percent% (182 of 3458 infants), as compared with a rate ...

Presentations at Leading Neurosurgery Meeting Highlight Benefits of CyberKnife Radiosurgery for the Treatment of CNS Indications

...bilities and benefits. At this year's AANS meeting, doctors presented on their experience treating intracranial tumors and spinal arterial venous malformations (AVMs) with CyberKnife radiosurgery. Key findings include: Randall W. Porter, M.D., from Barrow Neurological Institute presented ex...

Five UCSF Scientists Elected to National Academy of Sciences

...ons are refined, both prenatally and during infancy - researchers hope to be able to prevent nerve connections from forming incorrectly and to correct malformations when they do occur. Understanding the way in which the brain assembles and wires itself could provide insights into the cause of developmental dis...
malformations in Medical Technology

Scientists Discover Why Teeth Form in a Single Row

...d Osr2 to begin pinpointing the genetic network that controls teeth patterning and palate development. Their goal is to manipulate stem cells to treat malformations and to develop prevention strategies for cleft palate (e.g. the inclusion of folic acid in prenatal vitamins prevents neural tube defects in some case...

Advocate Christ Medical Center Using Glue-Like Liquid to Seal Off Brain Aneurysms

...s expertise in the treatment of brain aneurysms, the Christ Medical Center Neurosciences Institute also is a leader in the treatment of brain vascular malformations and stroke. In fact, last year, the Joint Commission, a national health care accrediting agency, awarded the medical center a two-year certification a...

Ardea Announces Progress with HIV Non-Nucleoside Reverse Transcriptase Inhibitor Program

... demonstrated no effects on male or female fertility or on early embryonic development at all tested doses. These results are in contrast to the fetal malformations reported in other NNRTI animal reproductive toxicity studies. Exploratory human testing (Phase 0) of RDEA427 was recently completed in which micro-d...

Elekta Announces Clinical Start-Up of New Leksell Gamma Knife(R) Perfexion(TM) at UPMC

...day. Gamma Knife(R) surgery is used to treat numerous neurosurgical conditions, including brain tumors such as metastatic cancer, as well as vascular malformations and certain functional disorders. This unmatched method provides pinpoint accuracy, high efficiency and outstanding results. Patients benefit from fas...

New England Journal of Medicine Publishes New Data on Gardasil, Merck's Cervical Cancer Vaccine

...g, fertility, pregnancy, parturition, lactation, embryo-fetal or pre- and postweaning development were observed. There were no vaccine-related fetal malformations or other evidence of teratogenesis noted in this study. In addition, there were no treatment-related effects on developmental signs, behavior, repro...

Data Published in The Lancet Show Gardasil was 100 Percent Effective in Preventing High-Grade Vulvar and Vaginal Lesions Caused by HPV Types 16 and 18

...g, fertility, pregnancy, parturition, lactation, embryo-fetal or pre- and postweaning development were observed. There were no vaccine-related fetal malformations or other evidence of teratogenesis noted in this study. In addition, there were no treatment-related effects on developmental signs, behavior, repro...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

...imes human exposure at the maximum recommended human dose (MRHD) of 100 mg/day based on AUC comparisons. Higher doses increased the incidence of rib malformations in offspring at 1000 mg/kg, or approximately 100 times human exposure at the MRHD. Sitagliptin administered to female rats from gestation day 6...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

...imes human exposure at the maximum recommended human dose (MRHD) of 100 mg/day based on AUC comparisons. Higher doses increased the incidence of rib malformations in offspring at 1000 mg/kg, or approximately 100 times human exposure at the MRHD. Sitagliptin administered to female rats from gestation day 6...
malformations in Medical Products

Onyx® Liquid Embolic System

Description:... Onyx Liquid Embolic System is a device utilized for the pre-surgical embolization of arteriovenous malformations (AVMs)....
Company:ev3, Inc.

Matrix Detachable Coils

Description:...nal operative techniques, or b) inoperable. Matrix Coils are also intended for embolization of other neurovascular abnormalities such as arteriovenous malformations and arteriovenous fistulae. Matrix Coils are also intended for arterial and venous embolizations in the peripheral vasculature. Our proven stretch-r...
Company:Boston Scientific Corporation

Novalis

Description:...ery and radiotherapy (SRS/SRT), represents cutting-edge technology for highly precise treatments of brain as well as head & neck tumors, arteriovenous malformations and certain functional disorders....
Company:BrainLAB Inc.
malformations in Medical Dictionary

Venous

..... Detailed Information on Various Birthmarks, Hemangiomas and Vascular malformations ... Venous malformations (cavernous hemangiomas) are the most common symptomatic ... Explanati...

Port-wine stain

...tches, usually on the More than one-third of infants are born with a pink patch at the nape of the ... Port - wine stains (nevus flammeus) are malformations of tiny blood vessels that ... Read about port - wine stains, how to care for them, and, if necessary, what ... If your child's port - wine ...

Palate

... Discusses cleft lip and cleft palate , which are facial and oral malformations ... What Is the Outlook for Children With Cleft Lip or Clef Palate ? ... Provides links to news and article on cleft lip and cleft palate . Co...

Neoplasm

...or urothelial neoplasms merit referral to a urology subspecialist for ... Detailed Information on Various Birthmarks, Hemangiomas and Vascular malformations ... Infantile hemangioma is a benign neoplasm that commonly develops in neonates ... Neoplasm produces antibody. Unknown immune mechanis...

Hemangioma

...mangioma is suspected, the challenge for the physician is to be sure ... Detailed Information on Various Birthmarks, Hemangiomas and Vascular malformations ... Photo#2 and 3 show another infantile hemangioma (birthmark) in the lower lip. ... Hemangioma and hemangioma -like vascular tumors and ...

Genetic Disorders

...of the sutures of the skull, ... Encyclopedia of Genetic Disorders Part I, ... A brief discussion of genetic , chromosomal and congenital malformations geared for the Respiratory therapist. ... to Genetic Disorders . Pediatric Respiratory ... The Fetal Concerns Program assists families in learn...

Cleft lip or palate

...r cleft palate are caused by multiple genes inherited from both ... Discusses cleft lip and cleft palate , which are facial and oral malformations ... What Is the Outlook for Children With Cleft Lip or Clef Palate ? ... Learn about cleft lip and palate - incomplete formations of ...

Cerebral angiography

..... and uses of angiography or angiogram, performed by ... cerebral vascular disease, such as stroke or bleeding in the brain. blood vessel malformations ... Cerebral angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the brain. ...

Birthmark

...ioma and hemangioma-like vascular tumors and vascular and lymphatic ... Detailed Information on Various Birthmarks , Hemangiomas and Vascular malformations ... Varicoid form venous malformationlow flow vascular birthmark ) in the calf. ... Learn about birthmark removal procedures and how cosmet...

Arteriovenous malformation

...nt on MedicineNet.com ... How do arteriovenous malformations damage the ... More about Arteriovenous malformations : Causes and symptoms Diagnosis Treatment Prognosis Resources Arteriovenous malformations Definition An arteriovenous malformation ...
malformations in Biological News

Brain malformations significantly associated with preterm birth, Wake Forest research shows

WINSTON-SALEM, N.C. New research out of Wake Forest University School of Medicine provides for the first time a solid scientific answer for the long-standing question of whether there is an association between preterm birth and brain malformations. In a study of more than 1,000 preterm infant...

Embryo biopsy does not affect early growth and risk of congenital malformations in PGD/PGS babies

This release is also available in Spanish . Barcelona, Spain: A study of 70 singleton babies born after preimplantation genetic diagnosis and screening has shown that the procedure does not adversely affect their early growth and risk of congenital malformations. The lead researcher, ...

Gene is likely cause of stroke-inducing vascular malformations

UCSF scientists have discovered that a gene controlling whether blood vessels differentiate into arteries or veins during embryonic development is linked to a vascular disorder in the brain that causes stroke. The UCSF studies were done in mice, and the new findings are the first to provide inf...

ICSI or IVF: Babies born from frozen embryos do just as well

...and, although they found a slightly higher rate of malformations in babies born from medicated cycles, the differen...es, gestational ages, birth weights and congenital malformations were similar for both IVF and ICSI singleton babie...ot significantly impair offspring outcome." The malformations ranged from heart defects to defects caused by her...

Complications early in pregnancy or in previous pregnancies adversely affect existing or subsequent pregnancies

...ditions; in addition, it increased the risk of placenta praevia (where the placenta partially or completely blocks the cervix) six-fold and congenital malformations nearly two-fold. If a previous pregnancy had to be terminated for any reason, this increased the risk of premature rupture of the membrane, premature ...

Why the thumb of the right hand is on the left hand side

...centration-dependent and controls the pattern formation of an organism. A mutation in this signaling pathway induces dramatic and embryonically lethal malformations in the early developmental stage such as the formation of just one central eye. Defects in the Hedgehog signaling pathway in humans are a cause for on...

Mouse model provides a new tool for investigators of human developmental disorder

...ctural defects might contribute to WHS symptoms, as is the case in the heart defects and swallowing difficulties. The report, "Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice" was written by Catarina Catela, Daniel Bilbao-Cortes, Esfir Slonimsky, Paschalis Kr...

Frogs reveal clues about the effects of alcohol during development

...tal alcohol spectrum disorder (FASD) and Fetal alcohol syndrome (FAS) cause malformations in babies, including facial defects, short stature, and mental and behavior...tal alcohol spectrum disorder (FASD) and Fetal alcohol syndrome (FAS) cause malformations in babies, including facial defects, short stature, and mental and behavior...

Bone deformities linked to inbreeding in Isle Royale wolves

...ertebraewhich can cause full or partial paralysis of the rear legs and tail, as well as back pain. It is a condition also seen in domestic dogs. Other malformations were found in the wolves as well. For the last 12 years, every one of the dead wolves the researchers have found has displayed bone deformities. ...

UF scientist tapped by Howard Hughes Medical Institute to pursue 'best ideas'

...cesses that take place in external genitalia development, like outgrowth and closure of the urethral tube," Cohn said. "The incidence of genitourinary malformations in humans came as a huge surprise to me. A staggeringly high frequency of one in 250 kids has a urethral tube defect, and that number has more than do...
malformations in Biological Technology

Scientists identify gene vital to early embryonic cells forming a normal heart and skull

...fy to form certain tissues. Although the study was conducted using mouse embryos, the findings are significant in efforts to understand congenital malformations of the heart and craniofacial region in people. Especially relevant, the researchers said, is the insight gained into early molecular events during em...

First U.S. Implants of Newly Approved Embozene(TM) Color-Advanced Microspheres Embolization Platform

... embolization platform for the treatment of hypervascularized tumors (tumors with a large number of blood vessels in many locations) and arteriovenous malformations (defects in the circulatory system), CeloNova BioSciences today announced that the product has been successfully used to treat several patients at two...

March of Dimes Awards $250,000 Prize to Leaders in Understanding Embryonic Development

...in signal and its attachment to cholesterol, and led to an understanding of malformations caused by deficiencies in hedgehog signaling, including brain and facial malformations associated with holoprosencephaly (when the brain fails to completely devel...
malformations in Biological Definition

Edward's syndrome

...l jaw; small mouth; low-set ears; and clenched fists with overlapping fingers. Those with Edward's syndrome also have heart defects , and other organ malformations such that most systems of the body are affected. Edward's Syndrome also results in significant developmental delays. For this reason a full-term E...

Infertility

...ndometriosis Pelvic adhesions Pelvic inflammatory disease (PID, usually due to chlamydia ) Tubal occlusion Uterine factors Uterine malformations Uterine fibroids ( leiomyoma ) Asherman's Syndrome Cervical factors Cervical stenosis Antisperm antibodies Vaginal factors V...
malformations in Biological Dictionary

Heritability

...s are always relative to the genetic and ... Britannica online encyclopedia article on heritability (biology), Although hereditary diseases and malformations are, unfortunately, by no means uncommon in the ... MU Extension, University of Missouri ... Heritability is the single most important considerat...
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