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Reducing malarial transmission in Africa

There are 300 million cases of malaria each year worldwide, causing one million deaths. Around 90% of these deaths occur in Africa, mostly in young children. One of the greatest challenges facing Africa in the fight against malaria is drug resistance; resistance to chloroquine (CQ), the cheapest and most widely used antimalarial, is common throughout Africa, and resistance to sulfadoxine-pyrimeth...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

Researchers at Georgetown University Medical Center say they are moving closer to understanding why the most lethal form of human malaria has become resistant to drug treatment in the past three decades. They have been able to artificially construct, and then express in yeast, a protozoan gene that contributes to such resistance. And it was no small feat. The gene they laboriously constructed...
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Misleading anti-malarial drug

Promotional claims about the preventive efficacy of a malaria drug are being questioned by experts, who say the statements are misleading and should be withdrawn. Manufacturer GlaxoSmithKline markets the anti-malarial drug Malarone (atovaquone and proguanil) as being 97 per cent effective at preventing the aggressive falciparum strain of malaria, but the Drug and Therapeutics Bulletin (DTB) – pub...

Malarial gene ascertained

Researchers from UK have identified Australian researchers have identified a gene which allows the malaria parasite, Plasmodium falciparum, to develop imperviousness to antimalarial drugs.Plasmodium,is a single-celled organism which is transmitted to humans via the saliva of a biting mosquito, has historically evaded control efforts by building resistance to virtually all of the drugs used to tr...

Chloroquine and Primaquine combination Malarial drug for resistant parasites.

Researchers from LaTrobe University of Australia have found a new combination drug for combating Plasmodium falciparum, the parasite responsible for causing malaria. They used a combination of Chloroquine and Primaquine for treatment // helps in killing P. falciparum which is resistant to Chloroquine drug. Chloroquine is a largely used drug in the treatment of malaria since 1950s. Chlo...

Older Malarial Drugs Vs New Ones

In the 2000 World Health Organization (WHO) report it was stated that Malaria affects 300 to 500 million people every year across the world and is one of the leading// cause of illness and death in the sub-Saharan African countries. A new study conducted by Dr. Hasifa Bukirwa of the Uganda Malaria Surveillance Project and Julia Critchley of the Liverpool School of Tropical Medicine in England sta...

Malarial Epidemic In Tripura Takes Its Death Toll To 65

Health officials in Tripura have announced that, they are taking preventive steps with as many as 65 people having died of malaria from the past three months//. A senior health official has said that a Central team is also scheduled to visit Tripura to assess the situation and to provide expert help to deal with reports of drug resistance. He also stated that almost 200 teams, consi...

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