Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
In a finding that broadens our insight intothe cause of certain kinds of UV-induced skin cancer, researchers atErasmus University Medical Center (Rotterdam, The Netherlands) haveemployed an evolutionarily ancient enzyme-repair system to identify theprincipal type of DNA damage responsible for the onset of skin-tumordevelopment. The researchers' findings also suggest that this enzymesystem m...Plants, animals share molecular growth mechanisms
A newly discovered plant protein complex that apparently switches on plants' growth machinery, has opened a scientific toolbox to learn about both plant and animal development, according Purdue University scientists. The protein complex triggers communication between molecules along a pathway that leads to the creation of long protein strings, called actin filaments, that are necessary fo...Male circumcision reduces risk of HIV transmission from women to men
The first study to examine the probability ofHIV infection per act of heterosexual sex among a population withmultiple sexual partners has found that uncircumcised men have morethan twice the risk of acquiring HIV than do circumcised men.In the study, published in the Feb. 15 issue of The Journal ofInfectious Diseases, now available online, Jared Baeten and colleaguesfrom the United States...Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
Sacramento - Today, Affymetrix, Inc.announced plans to make eight new GeneChip(R) plant and animal genomearrays available in 2005 as part of its Consortia Program, includingcanine, Rhesus macaque, Medicago trancatula (legume), Brassica, tomato,citrus, poplar and sugar cane. More than 20 research presentations atthis week's Plant and Animal Genome Conference XIII in San Diego,Calif. feature...Study Links Ebola Outbreaks To Animal Carcasses
All recent Ebola virus outbreaks in humans in forests between Gabon and the Republic of Congo were the result of handling infected wild animal carcasses, according to a study by the Wildlife Conservation Society (WCS) and its regional partners. Appearing in the February edition of the journal Emerging Infectious Diseases, the study found that many animal carcasses tested for Ebola between 2001 an...Mastercycler ep gradient S thermal cycler from Eppendorf North America
Description:To keep pace with these technological advances, the challenges of tomorrow must b...AccuSpot LC-MALDI Plate Spotter from Shimadzu
Description:The AccuSpot automates LC micro-fractionation, spotting and preparation for MS analysis. With the AccuSpot system, LC eluent can be accurately and continuously spotted onto target plates, in trace amounts. This allows for automatic preparation of target plates for MALDI-TOF-MS measurements. When used in conjunction with Shimadzus Two-Dimensional Micro LC System and Shimadzu Biotechs AXIMA MALDI-T...Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.
Description:ions and aligns them with histological images so you can localize drugs and metabolites prior to synthesizing radiolabeled c...Small Non-coding RNA Discovery Microarray - Comprehensive Service from LC Sciences
Description:LC Sciences provides a comprehensive microarray service for systematic discovery of small regulatory/functional RNA embedded within non-coding RNAs (ncRNAs) using a novel Paraflo technology and proprietary probe design, which enables highly sensitive and specific direct detection of small RNAs (1). This comprehensive service includes custom probe design (according to submitted target RNA sequence...Canine Pancreatic Microsomal Membranes from Promega
Description:Microsomal vesicles are used to study co-translational and initial post-translational processing of proteins. Processing events such as signal peptide cleavage, membrane insertion, translocation and core glycosylation can be examined by the translation of the appropriate mRNA in vitro in the presence of these microsomal membranes. In addition, processing and glycosylation events may be studied by...A Positive Selection Assay for Mutation Analysis in Big Blue Animals
Select-cII mutation assay kit Animals Stratagene Stratagene now offers an alternative way to perform mutational analysis inthe Big Blue<sup...New Mammalian Two-Hybrid System Detects Protein-Protein Interactions
Stratagene hybrid genes are used to detect protein-protein interactions via the activationof reporter gene expression. This expression occurs as a resul...Highest Transfection Efficiency of an Endotoxin-Sensitive Mammalian Cell Line
midiprep kit Stratagene EF plasmid midiprep kit, a kit based on anion exchange chromatography, magneticbeads, and cesium ch...An Epitope Tagging Vector for Gene Expression in Mammalian Cells
Stratagene The pCMV-Tag1 vector is an epitope tagging vector designed for geneexpression in mammalian cells. A target gene inserted into the pCMV-Tag1 vectorca...Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results
Michelle Cayouette Jane Moores Jason Capodanno Michael Rahilly Stratagene produces consistent PCR results in every well. The RoboCycler systems uniquedesign uses thermal blo...Feeding channel created by malaria parasite - a new target for malaria treatments
Researchers have found pore-like holes in the membranes of red blood cells infected by the deadliest form of the malaria parasite. The parasite, Plasmodium falciparum, apparently uses these holes to supply itself with the nutrients it needs to grow and reproduce. The discovery may lead to the development of new treatments for malaria, a widespread and devastating disease. Mala...Transdermal HRT not cardioprotective in postmenopausal women with CAD
Transdermal hormone replacement therapy (HRT) does not reduce the risk of cardiac events in postmenopausal women with existing coronary artery disease (CAD). In the PHASE trial (Papworth HRT Atherosclerosis Study), researchers randomized 255 postmenopausal women with angiographically proven coronary artery disease to receive either transdermal HRT--17-beta-estradiol with or without cy...Endangered species may be successfully cloned in another animal's womb
Scientists for the first time have found a way for the survival of endangered animal species of the world. In a major breakthrough a Massachusetts scientists who engineered the feat has managed to clone cells from an endangered animal (Asian Gaur) and successfully impregnated an Iowa cow with the clone. The scientific journal Cloning has reported in its upcoming edition that...Transdermal HRT not cardioprotective in postmenopausal women with Coronary Artery Disease
Transdermal hormone replacement therapy (HRT) does not reduce the risk of cardiac events in postmenopausal women with existing coronary artery disease (CAD). In the PHASE trial (Papworth HRT Atherosclerosis Study), researchers randomized 255 postmenopausal women with angiographically proven coronary artery disease to receive either transdermal HRT--17-beta-estradiol with or without cy...Heart disease in the newborn is related to maternal malnutrition
In its December issue Heart has carried a study on maternal malnutrition in the first trimester of pregnancy and how it causes coronary heart diseases in the newborn. Dr. Tessa .J. Rosé boom of the university of Amsterdam and her team have studied the occurrence of coronary heart diseases in children and correlated the findings to maternal malnutrition in the three trimesters of pregnancy...Ziegler Double Ended Lacrimal Dilator
Description:Double ended dilator probes with gentle curve. Stainless steel. Round knurled handle with polished finish. Overall length: 5.3 inches....Castroviejo Double Ended Lacrimal Dilator
Description:One end with needle point and other end with medium taper. Stainless steel. Round knurled handle with polished finish. Overall length: 5.7 inches....New Advances in Gastric Diagnostics: Smaller is Better
In recent years, miniaturization has opened up exciting possibilities in the area of gastric diagnostics. New technology may make routine GI diagnostic procedures as simple as swallowing a vitamin pill-sized encapsulated unit in the not-too-far future, and the present reality is that these units are becoming valuable adjuncts to traditional diagnostics. Capsule endoscopy (enteroscopy...Bench-Top Centrifuges--Basic Tools for the Small Lab
No matter how elementary or advanced, every clinical laboratory possesses one essential devicea centrifuge. It may be a bench-top or floor model, refrigerated or non-cooled, but this apparatus, because of its unique ability to fractionate liquid specimens by creating spin-induced high g-forces, has long been a standard tool for both diagnosis and research applications. For all this utility, t...Prothrombin Time Comes in Small (CLIA-Waived) Packages
Determining prothombin levels is necessary to plan or evaluate anticoagulant therapy, to diagnose various inherited conditions, such as hyperhomocystinemia, elevated factor VIII levels, dysfibrinogenemia, factor XII deficiency and disorders of plasmin generation, and to assess acquired conditions, such as pregnancy, postoperative state, antiphospholipid syndrome, hyperhomocystinemia, among ot...RTA 402 Shown to Protect Animals Against Toxicities of Standard Cancer Treatments
IRVING, Texas--(BUSINESS WIRE)--Jun 29, 2007 - ReataPharmaceuticals, Inc. today announced the presentation of newpreclinical data showing their lead anti-cancer agent, theSynthetic Triterpenoid RTA 402, is effective at protecting againstcommon toxicities caused by traditional cancer treatments. Thisdata was presented at the annual meeting of the MultinationalAssociation of Supportive Care i...