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Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell. Scientists have known for many years that an enzyme called Dam (DNA adenine meth...

Gambling monkeys give insight into neural machinery of risk

Duke University Medical Center neurobiologists have pinpointed circuitry in the brains of monkeys that assesses the level of risk in a given action. Their findings -- gained from experiments in which they gave the monkeys a chance to gamble to receive juice rewards -- could give insights into why humans compulsively engage in risky behaviors, including gambling, unsafe sex, drug use and overeatin...

Clearing jams in copy machinery

Bacteria and humans use a number of tools to direct perhaps the most important function in cells -- the accurate copying of DNA during cell division. New research published this week in Molecular Cell from the laboratory of Rockefeller University's Michael O'Donnell, a Howard Hughes Medical Institute Investigator, now shows that one of these proteins, the beta sliding clamp, serves as a toolbelt...

Machinery of the 'marijuana munchies'

Marijuana--or more specifically its active ingredient, tetrahydrocannabinol--has a well-documented tendency to stimulate hunger. And while scientists have traced this property to cannabinoid receptors in the brain, they have had little understanding of the neural circuitry underlying this effect. Understanding this circuitry has important practical implications because blocking the cannabi...

New insight into machinery of immune cells' 'tentacles'

Researchers have identified new molecular components of the machinery that regulates formation of the tentacle-like filaments by which immune system T cells grasp other cells. This embrace by such filaments is critical for the T cell to establish communication with cells called "antigen presenting cells" (APCs). Such communication enables the T cell to program itself to target invading microbes f...

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Wisconsin Manufacturing and the Machinery for Change

Wisconsin got a much-needed boost from a recent , in which I discussed some of the economic reasons for a Wisconsin...
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Protein acts as "Master Switch" that cuts off cells' Cancer-Growth machinery

A Washington University research team headed by Shrikant Anant, PhD, is mighty excited about their new discovery that was reported in the journal, Molecular Cell. They have found a "master switch" - a protein named CUBGP2(cytidine-uridine-guanosine binding protein) - that makes cancer cells self-destruct. The findings that were published// apply only to cancer cells grown in a test tube. Human st...
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(Date:9/5/2008)...s the Latest Developments in Molecular,Testing and... /PRNewswire-USNewswire/ -- The practice of,pathol...g and the promise,of personalized medicine will ch...and other imaging technologies will change the way...ogists is taking a leadership role in,making sure ...
(Date:9/5/2008)...RNewswire-USNewswire/ -- The Health Resources,and ... million in grants to,increase and improve medical... grants continue President Bush,s historic expansi...w reach more economically,vulnerable and geographi...dministrator Elizabeth M. Duke said. "In 2007, mor...
(Date:9/5/2008)...tical ,anti-cloak, could bring objects out of hidi...-- Just in case someone develops a cloak of invisi... how to uncloak the objects it hides. , Accordi...in materials underneath an invisibility cloak woul...esearchers at Shanghai Jiao Tong University in Chi...
(Date:9/5/2008)...ain to commit to develop a National AIDS,Strategy ...p. 5 /PRNewswire-USNewswire/ -- The,Republican Nat...ion of the,domestic AIDS epidemic in the United St...erseas. Neither Presidential nominee Sen. John McC... mentioned AIDS in their remarks,to Convention del...
Breaking Medicine News(10 mins):Health News:Leaders in Pathology Meet in San Diego: Sept. 25 - 28, 2008 2Health News:HRSA Announces $39 Million in Grants to Expand, Improve Health Center Services 2Health News:Domestic AIDS Epidemic Ignored at Republican National Convention 2Health News:Domestic AIDS Epidemic Ignored at Republican National Convention 3
(Date:9/4/2008)...RBOR, N.Y. (Sept. 4, 2008) A variety of organism... biological rhythms, where the timing and duration...adjusted to allow them to adapt and survive, even ...cent years, significant advances have been made to...nd how they translate into modifications in cellul...
(Date:9/4/2008)...s available in German . , Cystic kidney disease...seases of the excretory organs are characterized b...haracteristic proteins in the renal cells. An inte...ientists from DKFZ and Heidelberg University Hospi...nvestigate these conditions. , The researchers ...
(Date:9/4/2008)...CR San Antonio Breast Cancer Symposium features th...slational and clinical breast cancer research. Thi...apeutic approaches, as well as strides being made ... help you take the best advantage of the symposium... encourage you to visit www.sabcs.org to view th...
(Date:9/4/2008)...h Wales have put aside their competitive interstat...roject, as announced by Innovation Minister Gavin ...Research, Verity Firth, today. , Scientists fro...and colleagues from New South Wales will compare t...stem cells: somatic cell nuclear transfer (SCNT) a...
Breaking Biology News(10 mins):Interdisciplinary volume on biological rhythms serves as both primer and in-depth resource 2Gaining a better understanding of kidney diseases 2Stem cell research puts interstate rivalry on hold 2New AHIP Study in Health Affairs Challenges Previous Assumptions About Medigaps Impact on Medicare Costs 14174 1New AHIP Study in Health Affairs Challenges Previous Assumptions About Medigaps Impact on Medicare Costs 14174 2New AHIP Study in Health Affairs Challenges Previous Assumptions About Medigaps Impact on Medicare Costs 14174 3Large Disparities in Kidney Testing Based on Disease Gender and State Quest Diagnostics Health Trends 28TM 29 Report Finds 14170 1Large Disparities in Kidney Testing Based on Disease Gender and State Quest Diagnostics Health Trends 28TM 29 Report Finds 14170 2Large Disparities in Kidney Testing Based on Disease Gender and State Quest Diagnostics Health Trends 28TM 29 Report Finds 14170 3Large Disparities in Kidney Testing Based on Disease Gender and State Quest Diagnostics Health Trends 28TM 29 Report Finds 14170 4Large Disparities in Kidney Testing Based on Disease Gender and State Quest Diagnostics Health Trends 28TM 29 Report Finds 14170 5Large Disparities in Kidney Testing Based on Disease Gender and State Quest Diagnostics Health Trends 28TM 29 Report Finds 14170 6Large Disparities in Kidney Testing Based on Disease Gender and State Quest Diagnostics Health Trends 28TM 29 Report Finds 14170 7The price paid for higher energy is highly dangerous to teeth 14167 1The price paid for higher energy is highly dangerous to teeth 14167 2An Important Message to Anyone Taking Viagra From The Women Who Love You and Zoller Labs 14163 1An Important Message to Anyone Taking Viagra From The Women Who Love You and Zoller Labs 14163 2
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