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Molecular machine may lead to new drugs to combat human diseases

The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients. Purdue University researchers froze one of these molecular machines, which are chemical complexes known as a Group I intron, at mid-point in its work cycle. When frozen...

Building a protein name dictionary from full text: a machine learning term extraction approach

The majority of information in the biological literature resides in full text articles, instead of abstracts. Yet, abstracts remain the focus of many publicly available literature data mining tools. Most literature mining tools rely on pre-existing lexicons of biological names, often extracted from curated gene or protein databases. This is a limitation, because such databases have low coverage o...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell. Scientists have known for many years that an enzyme called Dam (DNA adenine meth...

Gambling monkeys give insight into neural machinery of risk

Duke University Medical Center neurobiologists have pinpointed circuitry in the brains of monkeys that assesses the level of risk in a given action. Their findings -- gained from experiments in which they gave the monkeys a chance to gamble to receive juice rewards -- could give insights into why humans compulsively engage in risky behaviors, including gambling, unsafe sex, drug use and overeatin...

Clearing jams in copy machinery

Bacteria and humans use a number of tools to direct perhaps the most important function in cells -- the accurate copying of DNA during cell division. New research published this week in Molecular Cell from the laboratory of Rockefeller University's Michael O'Donnell, a Howard Hughes Medical Institute Investigator, now shows that one of these proteins, the beta sliding clamp, serves as a toolbelt...

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Machine at Biology Products

EZ-Tn5 Plasmid-Based Deletion Machine from EPICENTRE Biotechnologies

Description:The EZ-Tn5™ Plasmid-Based Deletion Machine is based on the simple, highefficiency Tn5 in vitro transposition system developed by Goryshin and Reznikoff, and by York et al. for generation of nested families of deletions and inversions by intramolecular transposition into DNA targets cloned in a transposon-containing plasmid vector. Although most researchers will be interested in using the sys...
Company:EPICENTRE Biotechnologies
Machine at Biology Technology

Rapid PCR* Using Active Tube Temperature Control On Thermo's PCR Machines

Solutions Note The time taken to complete a standard PCRprotocol is becoming increasingly important forresearchers today. Whilst many manufacturers ofthermal cyclers focus on pushing the limits of ramprates, in this article we highlight how Thermo's approach of focussing on ach...

Voting machine source code must be available for review

Correction: the original story was based on an official summary that referred to the bill as introduced and did not take into account certain amendments. Under the law as enacted, the source code would be placed into escrow with the elections board. It would be analyzed in the case of a recount, but not open to the public. WTN very much regrets the error and any confusion it may have caused.</...

Machine like me

Computers aren't very good at tolerating unexpected difference. The boxes tend to get sulky and intractable when they encounter a spike in their power curve or an unanticipated condition in the data stream. They're a little like us that way. The difference, of course, is our ability to manage our own intractability, assuming we recognize it and choose to do somethin...

My 50 cents: Web sites and pinball machines

A pinball machine is a great metaphor for describing how a Web site works not the mechanical side of working that involves ASP, PHP and databases, but the reality of how a...

Milwaukee Brewers to get X-ray machine

Eastman Kodak Company, through its division, will provide a <a href="http://w...

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Machine at Medicine News

FDA approves first pocket-sized EKG machine

The government approved the first pocket-sized EKG machine, so small that it promises easier, faster heart measurements in ambulances, the emergency room - even a possible heart attack victim's bedroom. It's also the first hand-held computer-based medical device, part of a growing trend to miniaturize some of medicine's most important equipment. Electrocardiograms, also called EKGs or...

Machines take over the battle against hospital bugs

Hospital acquired infection is one of the most common reason which results in fatal complications among hospital patients. One of the most common and potentially dangerous bug which causes this type of infection is the bacterium// called acinetobacter. This bacterium is found naturally in the environment and survives drying and thrives in dust and on inanimate surfaces for long periods. This bac...

Condom Vending Machines Increasing Sexual Assaults On Women

The recent publication of the UN report shows staggering figures on the spread of AIDS and HIV //world wide, which also included India. The Indian Government thought it was taking a very positive step by installing ‘Anytime Condom” vending machines in commonly accessed public places. This included places like the bus stands, railway stations and public bathrooms especially in well educated states...

Protein acts as "Master Switch" that cuts off cells' Cancer-Growth machinery

A Washington University research team headed by Shrikant Anant, PhD, is mighty excited about their new discovery that was reported in the journal, Molecular Cell. They have found a "master switch" - a protein named CUBGP2(cytidine-uridine-guanosine binding protein) - that makes cancer cells self-destruct. The findings that were published// apply only to cancer cells grown in a test tube. Human st...

New X-ray machine launched by GE Healthcare

GE Healthcare, a division of US-based General Electric (GE), Tuesday launched HF Advantage, the next generation X-ray system designed, developed and made in India for the domestic and international markets. // Powered by high-frequency X-ray technology, the state-of-the-art product is equipped with a high-power 32KW generator hitherto used in high-end CTs and X-ray machines....

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Machine at Medicine Products

PRECISION GRAFT Machined Cortical Ring

Description:An all-cortical structure provides the structural benefits of cortical bone. Precision machined to exact specifications to promote healthy lordosis and vertebral body distraction....
Company:Regeneration Technologies, Inc.

The Hacker HCM4000 Automatic CoverSlipping Machine

Description:The exclusive mountant media dispensing system eliminates the formation of air bubbles under the coverglass. All new microwaveable slide baskets interface with most automated staining machines. Available with semi-disposable, ready to load, pre-filled coverglass and mountant dispensers. Compact footprint requires minimal counterspace....
Company:Hacker Instruments & Industries

PL-A741 Mono 1.3 Megapixel Machine Vision Camera

Description:The PL-A741 is PixeLINKs most popular machine vision camera. It is a monochrome 1.3 megapixel digital FireWire camera with global shutter, external trigger and a rich set of on-board features that provides high-quality ditigal video streams to the computer. The PL-A741 combines the functionality of a frame grabber with a CMOS imager to provide a solid machine vision camera in a simple to use p...
Company:PixeLINK

GeneMachines HybStation

Description:The GeneMachines HybStation is the first automated system for the hybridization of microarrays. The unit automates all thermal and wash cycles for the hybridization of microarrays spotted on standard glass slides. Mini...
Company:Genomic Solutions

GeneMachines Hyb4

Description:The GeneMachines Hyb4 is built upon the success of the first automated hybridization for microarrays. The unit automates all thermal and wash cycles for the hybridization of microarrays spotted on standard glass slides. Minimizes handling...
Company:Genomic Solutions

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Machine at Medicine Technology
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Breaking Biology News(10 mins):Greenland ice core reveals history of pollution in the Arctic 2Regional Law Enforcement Data Exchange System Expands 2Regional Law Enforcement Data Exchange System Expands 3Workers Settle Contract at 10 Bay Area Nursing Homes 23160 1Workers Settle Contract at 10 Bay Area Nursing Homes 23160 2Study 3A 9 11 Dogs Suffered Few Health Effects 23157 1Study 3A 9 11 Dogs Suffered Few Health Effects 23157 2State National Long Term Care Community Applauds Arkansas Leaders in U S Senate and U S House for Helping Lead Effort to Block 24770 Million Bush 23152 1State National Long Term Care Community Applauds Arkansas Leaders in U S Senate and U S House for Helping Lead Effort to Block 24770 Million Bush 23152 2State National Long Term Care Community Applauds Arkansas Leaders in U S Senate and U S House for Helping Lead Effort to Block 24770 Million Bush 23152 3Pharmacy Students Taught Improved Medication Adherence and Holistic Health Services Through Program Incorporating InforMedixs Med eXpert 28TM 29 Syste 6360 1Pharmacy Students Taught Improved Medication Adherence and Holistic Health Services Through Program Incorporating InforMedixs Med eXpert 28TM 29 Syste 6360 2Pharmacy Students Taught Improved Medication Adherence and Holistic Health Services Through Program Incorporating InforMedixs Med eXpert 28TM 29 Syste 6360 3Pharmacy Students Taught Improved Medication Adherence and Holistic Health Services Through Program Incorporating InforMedixs Med eXpert 28TM 29 Syste 6360 4
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