Source of molecular triggers in cutaneous T cell lymphoma identified
In a study published in the journal Blood, Yale scientists identify the molecular triggers that stimulate Cutaneous T Cell Lymphoma (CTCL) cells to clonally expand into large populations of malignant lymphocytes. CTCL is the most common adult malignancy of T lymphocytes, the white blood cells of the immune system. Finding CTCL triggering factors has been a major goal of Richard L. Edelson...Potential Cure for Lymphoma in HIV patients
Stem cell transplants have become thestandard of care for patients with relapsed lymphoma, but not forpatients who suffer from both this disease and HIV. A new study showingthat this treatment is a viable option for select patients withHIV-associated lymphoma will be published in the January 15, 2005,issue of Blood, the official journal of the American Society ofHematology.Because of the i...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
The genes TEL2 and MYC cooperate with each other to promote pediatric cases of the immune system cancer B-cell lymphoma. This finding, from investigators at St. Jude Children's Research Hospital, is published in the current issue of Molecular Cell Biology (MCB). B-cell lymphoma is a cancer in which the antibody-producing cells (B lymphocytes) multiply uncontrollably and crowd out other blo...New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
A new form of treatment for lymphoma that takes a fraction of the ti...Reversal of role for a viral protein associated with the development of lymphoma
Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns). During processing, introns are snipped out and exons pasted together to form a template for proteins called messenger RNA (mRNA). Mistakes in RNA processing can reduce the expression of a function...EL - 4 cell line slides ( mouse: T lymphocyte; lymphoma ) from GeneTex
Description:Mouse EL-4 cells were cultured in DMEM and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background staining. Each well is loaded with approximately 7. 5 x...Raji cell line slides ( human: B lymphocyte; Burkitt's lymphoma ) from GeneTex
Description:Human Raji cells were cultured in RPMI 1640 medium with 2 mM L-glutamine and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background staining. Each well is...Lymphoma's Link to Hepatitis C
Researchers at the University of Hopkins found a new study shows some cancer patients who also have the hepatitis C virus may benefit from treatment with the drug, interferon.Past research has suggested a connection between the hepatitis C virus and some B-cell non-Hodgkin's lymphoma's. //A patient with both of these diseases was treated with the antiviral treatment interferon. The patient resp...Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas
Stanford, CA -- Successful eradication of Helicobacter may not prevent future aggressive gastric lymphoma since resting B cells are left behind. This was reported by Research led by Dr. Anne Mueller at Stanford University // School of Medicine. The paper by Mueller et al., "The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MA...Artificial sweetener, Aspartame, may be the potential cause of lymphoma, leukaemia
It has been found through an animal study that Aspartame can cause lymphoma, leukaemia. The study points out that drinking four to five 20-ounce bottles of diet soda sweetened with aspartame each day would be the //cause of cancers. The study would be published in March issue of Environmental Health Perspectives, an US government-run environmental science journal. The method...No Lymphoma Risk From Rheumatoid Arthritis Drugs
There has been an increasing fear regarding the elevated risk of lymphoma associated with rheumatoid arthritis treatment// A new study by Swedish researchers has found that such treatments may not confer an increased susceptibility to cancer, the results of which can be seen in the latest issue of Arthritis & Rheumatism journal. The risk of cancer has been found to increase with worse...Leukemia/Lymphoma Phenotyping (Comprehensive-Bone Marrow)
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Leukemia/Lymphoma Phenotyping (Comprehensive - Miscellaneous)
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Leukemia/Lymphoma Phenotyping (Comprehensive-Whole Blood)
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...