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Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

New work reported in the March issue of Cell Metabolism has provided insight into a key mechanism by which cells limit cholesterol synthesis. The finding suggests a novel approach to the development of cholesterol-lowering drugs that may boost the effect of statins, one of the most prescribed cholesterol inhibitors, according to researchers at the University of Texas Southwestern Medical Center.<...

Medical whistleblowers speak out

The US Food and Drug Administration (FDA) was "the single greatest obstacle to doing anything effective" about Vioxx, said FDA drug safety officer David Graham at an unprecedented roundtable of medical whistleblowers sponsored by the Public Library of Science (PLoS) and the Government Accountability Project. In comments that echoed his now infamous testimony to the US Senate Finance Commi...

The evolutionary triumph of flower power

Enjoying spring flowers? Flowers have flourished ?their beauty evolving over time ?simply because we like them, says Terry McGuire, associate professor of genetics at Rutgers and co-author of a paper that examines for the first time the whys and wherefores of flowering plants in an evolutionary context. While flowers originally came on the scene to attract potential pollinators like bugs...

Bumblebees copy one another when contending with unfamiliar flowers

Researchers have reported findings that offer a surprising new twist to our understanding of how bumblebees, a vital floral pollinator, select the flowers from which they collect nectar. When faced with unfamiliar plants, foraging bees do not choose flowers entirely alone but instead copy the choices of other bees. The new findings suggest that bees adjust their behavior when dealing with flowers...

Analysis of flower genes reveals the fate of an ancient gene duplication

In a step that advances our ability to discern the ancient evolutionary relationships between different genes and their biological functions, researchers have provided insight into the present-day outcome of a single gene duplication that occurred over a hundred million years ago in an ancestor of modern plants. The work is reported in Current Biology by a team led by Brendan Davies of the Univer...

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Lowering the fear factor for entrepreneurs, intra-preneurs

MILWAUKEE,WI.-Beware calling the next strange idea you hear strange: the person touting it just might be the next millionaire next door. A panel of experienced entrepreneurs speaking to attendees at the first Wisconsin Entrepreneurs Conference in Milwaukee last Wednesday have dealt with looks and whispers their entire working lives, and they encouraged their brethren in the audience to...

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Spouses and other partners lower blood pressure says new research

The May issue of Psychosomatic medicine reports that spending a little quality time with one's spouse and other partners seems to have a calming influence on a person's blood pressure. In a study that used portable monitors to track people's blood pressure, it turned out that the participants' pressure was lowest when they were with their partners, regardless of what they were doing....

Brisk Walking lowers memory loss in women

According to a research presented during the American Academy of Neurology in Philadelphia, brisk walking may help women keep their brains young. Women who walk regularly are less likely to experience the memory loss and other cognitive declines in mental function that can come with aging.// In the study, they concluded that the least active women walked an average of about a half mile...

B Vitamin protects and lowers toxicity of Arthritis Drug

Rheumatoid arthritis is an autoimmune disease that most often affects women in their 30s and 40s, especially women.The illness causes the immune system to attack the joints, which can cause pain, inflammation and joint destruction. Methotrexate is the standard drug used to treat the condition, but one third of the patients discontinue treatment early due to toxicity.//...

Tea drinkers have lower rates of heart disease

In comparison to coffee, tea drinkers have lower rates of heart disease and cancer, although few clinical studies have been done. Doctors are carrying out research into the effect of green tea in men with prostate cancer. They hope it will be just one of the many studies that will be done on the benefits of tea.// Generally tea drinkers are less likely to have heart disease or cancer, although t...

Estrogen lowers cancer risk

Italian scientists have found that women had about a 20 percent lower chance of developing cancer if they used oral contraceptives. This new research bolsters the theory that the female hormone estrogen might protect women from colorectal cancer. Dr. Carlo La Vecchia, who led the study said "For a while now we have suspected that estrogen in the pill could protect against bowel c...

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TiMAX Pe.R.I. Small Fragment Lower Extremity Plate

Description:The advanced performance benefits of TiMAX material have been applied to a new Pe.R.I. (Periarticular Reduction Implants) system. Greater strength and an ultra-low profile combine to provide a complete set of periarticular plates for the lower extremity. This complete set of periarticular plates consists of:...
Company:DePuy Orthopaedics, Inc.

Half Apron - Lower

Description:Mini: 12" x 14" Small: 14" x 16"Medium: 16" x 18" Large: 18" x 20"...
Company:MarShield

Ultra Lower Leg Walker

Description:Fracture walker designed to provide maximum comfort, protection and stability...
Company:Corflex, Inc.

Remote Blower With Bag-In/Bag-Out Option

Description:Remote Blower With Bag-In/Bag-Out Option...
Company:NuAire

Remote Blower Without Bag-In/Bag-Out Option

Description:Remote Blower Without Bag-In/Bag-Out Option...
Company:NuAire

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Point of Care Strep Tests Speed Treatment, Lower Costs

Beta-hemolytic group A streptococcus (S. pyogenes) is the most common bacterial agent associated with upper respiratory tract infections. Although it usually involves mild symptoms (such as headache, fever or abdominal pain) if left untreated streptococcal infection can worsen and become life-threatening. Early diagnosis and treatment of group A streptococcal pharyngitis has been shown to red...

Lexicon Develops Antibodies That Lower Triglycerides and Cholesterol as Potential New Therapy for Heart Disease

- Publication of New Cardiovascular Target from Lexicon's GeneticResearch - THE WOODLANDS, Texas, July 02, 2007 /PRNewswire-FirstCall/ --Lexicon Pharmaceuticals, Inc. today reported results frompreclinical research demonstrating that antibodies directed to apotential new target, angiopoietin-like protein 4 (ANGPTL4),rapidly lower triglycerides and cholesterol. Research suggests thata mon...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

CHICAGO--(BUSINESS WIRE)--Jun 23, 2007 - Late breaking datapresented at the American Diabetes Association (ADA) 67th AnnualScientific Sessions showed that, when used investigationally asinitial therapy, JANUVIA(TM) (sitagliptin) in combination withmetformin provided significant glycemic improvement and wasgenerally well tolerated over 54 weeks in patients with type 2diabetes. Additional new...

Breaking Multi-Center Study: Masimo SET Pulse Oximetry Technology Shown to Significantly Lower Instances of Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants

Study released at the Pediatric Academic Societies' Annual MeetingThis Month in Toronto Shows That Switching to Masimo SET PulseOximetry Technology Can Reduce the Risk Associated with ROP by 40% IRVINE, Calif., May 30, 2007 /PRNewswire/ -- Masimo, theinventor of Pulse CO-Oximetry and Read-Through Motion and LowPerfusion pulse oximetry, reported that a new independent studypresented at the...

Data Presented at ASH Demonstrate Nebivolol Lowers Blood Pressure as Long-Term Monotherapy and in Combination Therapy

Data Also Show Nebivolol Lowers Blood Pressure in Obese andNon-Obese Hypertensive Patients CHICAGO, May 21, 2007 /PRNewswire-FirstCall/ -- ForestLaboratories, Inc. today presented positive data from two clinicalstudies and one pooled analysis of nebivolol, a selective beta1-blocker with vasodilating properties currently under review bythe U.S. Food and Drug Administration (FDA) for the tr...

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