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loci in Medical News

Genetic loci assigned for musical aptitude in Finnish families

Molecular and statistical genetic studies in 15 Finnish families have shown that there is a substantial genetic component in musical aptitude. Musical aptitude was determined using three tests: a test for auditory structuring ability (Karma Music test), and the Seashore pitch and time discriminati...

Siemens Showcases Innovative Products and Educational Offerings

...es a number of automated, productivity-enhancing features. Dimension Vista(R) 500 System , offering ultra-integration of technologies including loci advanced chemiluminescence technology and onboard automation for enhanced sensitivity and efficiency. IMMULITE(R) 2000 XPi System , offering en...

A breakthrough in gastric carcinogenesis

...troenterology They investigated the promoter methylation of CHFR in 59 cases of gastric cancer using methylation-specific PCR. Five microsatellite loci were analyzed using high-intensity microsatellite analysis reported previously, and p53 gene mutations were investigated by direct sequencing. They...

NYU School of Medicine pathology researchers solve another mystery in B lymphocyte development

...ally in children. Chromosomal translocations involving the antigen receptor loci are a common underlying mechanism. "V(D)J recombination plays a crucial ...data suggest that in parallel with X inactivation, homologous pairing of Ig loci contributes to allelic exclusion by ensuring that only one allele is target...

Gene Studies Reveal Cancer's Secrets

...ncerous tissue with normal bladder tissue, they found 158 "hypermethylated" loci and 366 "hypomethylated" locations. In addition, they found 21 places that ...ormal-appearing bladder tissue in patients with bladder cancer. These loci may be markers for identifying people at risk for bladder cancer, the resea...

Multifocal lung cancers appear to originate from single cancer clone

...e whether multiple tumors from an individual patient shared a common genetic pattern. The investigators analyzed the tumors for chromosome loss at six loci previously associated with lung cancer and for mutations in the TP53 gene. They also analyzed the X-chromosome inactivation pattern in tumors from fem...
loci in Medical Technology

Scientists Unmask Genetic Markers Associated With Psoriasis

...ed the study to look at 18 of the most interesting loci in an additional 5,048 cases and 5,051 controls. In all, seven of the 18 loci showed consistently strong association with psoria...work by Elder and colleagues, links four psoriasis loci (IL12B, IL23A, IL23R and IL4/IL13) together in a c...

Major deCODE-led Study Underscores Role of the Brain in Obesity

... and subscribers will receive an update to their personal profiles. The paper, entitled "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity," is published today in the online edition of Nature Genetics at http://www.nature.com/ng , and will appear i...

Research Explores the Effects of Stem Cell Source and Patient Age on Stem Cell Transplantation Outcomes

...43 were matched at eight out of eight possible HLA loci and 111 were matched at seven HLA loci. In those r...tem cell transplant, 518 were matched at eight HLA loci and 210 at seven HLA loci. In those receiving cord...od transplants, 28 were matched at five or six HLA loci and 110 matched at four HLA loci. The stu...

Siemens Healthcare Diagnostics Launches B12, Folate, and Ferritin Tests on Its Dimension vista Intelligent Lab System

...or anemia in patients, and further expand Siemens' loci immunoassay test menu for the Dimension Vista Syst... common forms of anemia." Through the use of the loci Advanced Chemiluminescence Technology, Siemens Hea...metabolism, including Folate, B12, and Ferritin by loci technology; Iron and Total Iron Binding Capacity b...

Microarray Sequence Capture Speeds Large-Scale Resequencing of Targeted Genomic Regions

...study, entitled "Direct Selection of Human Genomic loci by Microarray Hybridization," appears online (ahea...rmance targeting of thousands of specific genes or loci using a single microarray hybridization-based enri... Gibbs RA. 2007. Direct selection of human genomic loci by microarray hybridization. Nat Meth. Published o...

Researchers Discover a Common Variation in a Gene Segment that Increases the Risk for Prostate Cancer

...83267, these two genetic changes could account for as much as one quarter of prostate cancer cases in white men. The increased risk conferred by these loci was observed for all age groups studied. CGEMS allows us to look systematically across the entire human genome and search for common genetic variati...
loci in Medical Products

Dimension Vista System

Description:... The Dimension Vista 1500 integrated system will combine photometry, turbidemetry, nephelometry, IMT (integrated multisensor technology) and loci technologies. The new design will integrate analysis of electrolytes, general and special chemistries, drugs-of-abuse, therapeutic drugs, immunosuppre...
Company:Dade Behring, Inc.

OLERUP SSP™ HLA Kits

Description:... Complete product line for typing all classical HLA loci including A, B, C DRA, DRB1, DRB3, DRB4, DRB5, DQA, DQB1, DPA1, and DPB1....
Company:QIAGEN

Vysis UroVysion Bladder Cancer Kit

Description:...red in hybridization buffer for ease of use. Unlabeled blocking DNA is also included with the probes to suppress sequences contained within the target loci that are common to other chromosomes. When hybridized and visualized, these probes provide information on chromosome copy number for chromosome ploidy...
Company:Abbott Diagnostics
loci in Biological News

Prostate Cancer Translational Research in Europe meeting: Search for biomarkers continues

...ion on PSA genetics may improve utility in screening. Rafnar also pointed out that although "...much work remains. finding causative variants at known loci define functions." The lecture by Prof. Freddie Hamdy (Oxford, UK), 'What is the best practice in bio-banking?' focussed on the dilemmas in prosta...

Domestication of Capsicum annuum chile pepper provides insights into crop origin and evolution

... and his team examined DNA sequence variation and patterns at three nuclear loci in a broad selection of semiwild and domesticated individuals. Dr. Kim et ...of long-distance seed dispersal by birds and mammals. Across the three loci studied, Dr. Kim and colleagues found an average reduction in diversity of ...

Identification of genetic variants affecting age at menopause could help improve fertility treatment

...th menopausal age, and a possible indication of the gene involved, but not a total proof of function", said Ms Stolk. "When we have a larger group of loci we intend to perform functional studies to study the exact biology and effect of this association." The scientists say that it may be several year ...

Study finds genetic links to age of first menstrual period and menopause

...e paper, "Genome-wide association studies identify loci associated with age at menarche and at natural men...more statistical power and revealed a total of two loci for timing of menarche and four for timing of meno...rofessor at Harvard Medical School, added, "Of the loci for timing of menopause, three were already strong...

New and improved tomato analyzer

... A main objective of the study was to investigate the quantitative trait loci (QTL), which are parts of the genetic code that control fruit shape. The QT...n the exterior silhouette alone. In the 'Sausage' species of tomato, two loci were identified as controlling more than 50% of the internal shape index, w...

When every photon counts

...antage of the conventional architecture is that the central positioning of the active eurochromatin allows more interactions between neighbouring gene loci and with the transcription apparatus in three dimensions; euchromatin in a peripheral shell factually has only two dimensions for contacts. However, i...
loci in Biological Technology

'Enrichment of Genomic Loci for Targeted Sequencing Application' Is Focus of 2009 AGBT Conference Workshop

LEXINGTON, Mass., Jan. 30 /PRNewswire/ -- Jeff Olson, Manager of Nucleic Acid Applications, of RainDance Technologies, Inc., will present " Enrichment of Genomic Loci for Targeted Sequencing Applications , " to explain application of the RainStorm micro-droplet technology on the new RDT 1000 in...

Fully automated DNA purification and efficient multiplex PCR for analysis of microsatellite loci

Marion Schmidt, Holger Engel, Markus Sprenger-Hauels, Corinna Kppers, Gaby Schulte, Silke Zobel, and Dirk Lffert QIAGEN GmbH, Hilden, Germany Microsatellites highly polymorphic DNA markers comprised of nucleotides ...

Automated Sequence Capture for Next-Generation Sequencing Paves the Way for Personalized Medicine

...es amongst geneticists: targeted re-sequencing of medically-relevant genome loci will greatly enhance the understanding of health and disease in crucial are...lysis) HybSelect will support the selection and enrichment of specific gene loci for Next Generation Sequencers. The new technology is available as a p...

RainDance Technologies Delivers RDT 1000, Sequence Enrichment Solution to The Genome Center at Washington University School of Medicine in St. Louis

...o the GC, along with customized PCR primer libraries to selectively amplify loci of interest for their research initiatives. Elaine Mardis, Ph.D., Co-Dire... in droplets enabling the amplification of hundreds to thousands of genomic loci in a single tube. The RainStorm format avoids the limitations of traditiona...

RainDance Technologies to Present Workshop on Sequence Enrichment Using Innovative Microdroplet-Based Solutions at ASHG 2008

...till economically unrealistic. To exploit the full potential of new sequencing techniques, a robust method for isolating biologically relevant genomic loci on the megabase scale will be required. Analogous to what the massively parallel sequencing technologies have done to improve the efficiency of DNA ...

RainDance Technologies to Present 'Sequence Enrichment Using Droplet-Based Microfluidics' Workshop at ASHG 2008

...ing techniques, a robust method for isolating biologically relevant genomic loci on the megabase scale will be required. Analogous to what the massively p...ips. We will present the use of this novel method for enrichment of genomic loci with minimal selection bias prior to sequencing, demonstrating the utility ...
loci in Biological Products

SeeSNP Discovery / Resequencing from Agencourt Bioscience

Description:... Agencourt offers SNP loci identification through targeting resequencing. This service includes automated assay design, intensive assay validation/optimization, high throughput...
Company:Agencourt Bioscience
loci in Biological Definition

Allele frequency

...locus, c) a population of individuals carrying n loci in each of their somatic cells (e.g. two loci in the cells of diploid species, which contain t...y of that allele is the fraction or percentage of loci that the allele occupies within the population. ...

Bacterial conjugation

...li themselves do not seem to be the structures through which the actual exchange of DNA takes place; rather, some proteins coded in the tra or trb loci seem to open a channel between the bacteria. The transfer of DNA always runs from the F-positive towards the F-negative bacterium. If the F-plas...

Genetics

...n data on the phenotype and relationships of individuals. A more recent development of quantitative genetics is the analysis of quantitative trait loci . Traits that are under the influence of a large number of genes are known as quantitative traits, and their mapping to a location on the chromosome...

Isozyme

...in the same individual . This definition encompasses (1) enzyme variants that are the product of from different genes and thus represent different loci (described as isozymes ) and (2) enzymes that are the product of different alleles of the same gene (described as allozymes ). Isozymes are u...

Locus

... The word locus (plural loci ) is Latin for "place". In biology and evolutionary computation , a locus is the position of a gene (or other significant sequence) on a ...

Major histocompatibility complex

...0, 500, and 300 known alleles respectively -- diversity which is truly exceptional in the human genome. And population surveys of the other classical loci routinely find tens to a hundred alleles -- still highly diverse. And perhaps even more remarkable is that many of these alleles are quite ancient: i...
loci in Biological Dictionary

Loci

In the fields of genetics and evolutionary computation, a locus (plural loci ) is a fixed position on a chromosome such as the position of a biomarker that may be occupied by one or more genes. A variant of the DNA sequence at a given locus is called an allele. The... The 'method ...

Quantitative trait loci

Inheritance of quantitative traits or polygenic inheritance refers to the inheritance of a phenotypic characteristic that varies in degree and can be attributed to the interactions between two or more genes and their... quantitative trait locus ( ′kwäntə′tādiv ¦trāt ′lōkəs ) ( gen...

Polymorphic loci

Comparison of agarose type (non- polymorphic loci ) ... These primers amplify polymorphic loci , and alleles of different sizes can be observed. ... Many polymorphic loci have been identified, and scientists have tried to ... Therefore, for any polymorphic locus , one of the allel...

X chromosome

...... Britannica online encyclopedia article on X chromosome (genetics), ...the sex chromosomes , designated XX in females and XY in males. The loci of the blood group ... used the X chromosome , particularly for investigating ... of the X chromosome for addressing the ... genetics, as t...

VNTR

... MIRU- VNTR (MLVA)-, Spoligo-, RD (LSP)-, and SNP-data. ... Change VNTR loci set. 24 loci. Change VNTR loci order ... Definition of VNTR from Merriam-Webster's Medical Diction...

Unlinked

...not display in the ... ... interaction detection between two unlinked loci have advantages, as follows. ... First, since interaction between two unlinked loci can be characterized by LD ... The need to use the unlinked anonymous...
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