AlphaRx Reports Positive Preclinical Data on GAI-122 Against Liver Disease
GAI-122, an investigational injectable nano-emulsion formulated with
AlphaRx's proprietary drug delivery technology, provides significant
hepatoprotection in multiple animal models of acute hepatitis suggesting
that GAI-122 may reduce necro-inflammation and may halt disease
pr...
Gene's novel role may provide key to treating liver and neurodegenerative diseases
Scientists at Singapore's Bioprocessing Technology Institute (BTI) have made a novel discovery about how the gene, "Fas-apoptosis inhibitory molecule" (FAIM), protects both immune and
liver cells from apoptosis, or programmed cell death.
Their research is published in the current journal Cell...
JNCI news brief: Hepatitis B virus mutations may predict risk of liver cancer
Certain mutations in the DNA of the hepatitis B virus (HBV) are associated with the development of
liver cancer and may help predict which patients with HBV infections are at increased risk of the disease, according to a large meta-analysis in the Journal of the National Cancer Institute , publis...
Exercise helps patients with non-alcoholic fatty liver disease
Counseling patients with non-alcoholic fatty
liver disease (NAFLD) on how to increase physical activity leads to health benefits that are independent of changes in weight. These findings are in a new study in the July issue of Hepatology , a journal published by John Wiley & Sons on behalf of the...
Study examines dietary influences of liver disease
Diets high in protein and cholesterol are associated with a higher risk of hospitalization or death due to cirrhosis or
liver cancer, while diets high in carbohydrates are associated with a lower risk. These findings are in the July issue of Hepatology , a journal published by John Wiley & Sons o...
Study examines liver transplantation after drug induced acute liver failure
Liver transplantation offers a good chance for survival for patients with drug induced acute
liver failure, however, certain pre-transplant factors are associated with worse outcomes. Patients who are on life support, who have elevated serum creatinine, and children whose
liver failure was caused ...
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Liver in Medical Technology
Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome
AIEA, Hawaii, July 20 /PRNewswire/ -- The Centers for Disease Control and Prevention reported this week that the prevalence of obesity among Americans is now over 26%. Obesity exacerbates a constellation of diseases including diabetes,
liver disease, and heart disease, often in...
ALP Life Sciences, LLC Announces Nanoveson(TM) Patent Filing and Whitepaper Availability on Proposed Therapy for Non-Alcoholic Fatty Liver Disease (NAFLD) and Comorbid Diseases
BLACK MOUNTAIN, N.C., June 24 /PRNewswire/ -- ALP Life Sciences, LLC (Company) today announced the Nanoveson(TM) patent has been filed and the Nanoveson(TM) whitepaper is available at www.ALPLifeSciences.com/wp . After completing initial research, the Company is pursuing clinical trials an...
No Causality Found Between Black Cohosh and Liver Problems
Results of a Randomized Study Presented at ACOG 2009 Annual Meeting Confirming Teschke's Re-evaluation of Spontaneous Reports
CHICAGO, May 5 /PRNewswire/ -- Black cohosh has been widely used in Europe and also in North America to treat menopausal symptoms including hot flashes, night sweats, ...
Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting
Final results from three large PEGINTRON(TM) clinical studies address key questions in the treatment of hepatitis C
COPENHAGEN, Denmark, April 27 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP ) today reported that final results of three large PEGINTRON(TM) (peginterferon ...
InterMune Reports Presentation of Triple Combination Study of ITMN-191 at European Association for the Study of the Liver (EASL)
- Results inform selection of doses, regimens to be explored in Phase 2b study -
-- Phase 2b program anticipated to begin in summer 2009 --
COPENHAGEN , April 24 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN ) today announced that results from a 14-day Phase 1b clinical stu...
MultiCell Technologies Signs Liver Stem Cell R&D Agreement To Develop Products for the Study of Liver Cancer
WOONSOCKET, R.I., March 19 /PRNewswire-FirstCall/ --MultiCell Technologies, Inc. (OTC Bulletin Board: MCET) announced today that it has entered into a cooperative research and development agreement with Maxim Biotech, Inc. to develop products for the study of
liver stem cells and
liver cancer.
...
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Liver in Medical Products
Soluble Liver Antigen Antibody, IgG
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Iron, Liver
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Fe, Liver
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Cu, Liver
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Copper, Liver
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Sequitor Steerable Guidewire
Description:...l vasculature for various interventional procedures, including both uterine fibroid embolization and embolization of hypervascularized tumors, such as
liver tumors....
Company:BioSphere Medical, Inc.
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Liver in Medical Definition
Atransferrinemia
...inemia is characterized by anemia and hemosiderosis in the heart and
liver . The iron damage to the heart can lead to heart failure . The anemia is t...hyroid , kidney and bone joints , leading to mild to severe symptoms of
liver and heart failure, arthropathy and hypothyroidism . Death may occur due...
Biotextile
...olely on synthetic foreign implanted material. One of Dr. Martin King's graduate students, Jessica Gluck, has demonstrated that viable and functioning
liver cells can be grown on textile scaffolds.
External links
website NC State’s College of Textiles on biotextiles
...
Excoriation
...itching/pruritus: dry skin, dermatitis , atopic dermatitis , scabies , etc. The condition is characteristic of a symptom of other illnesses like
liver failure where pruritus is caused by increases of bilirubin .
It is usually associated with neurotic excoriations . Neurotic excoriations are co...
Medical procedure
...lonoscopy
Laparoscopy
Esophageal motility study
Medical imaging
Angiography
Cerebral angiography
Coronary angiography
liver angiography
Renal angiography
Pulmonary angiography
Lymphangiography
Ventriculography
Aortography
Retinal angiography
Abreu...
Pathology
...sophagus - Eye - Gallbladder - Head/Neck -
liver - Larynx - Lung - Mediastinum (chest) - Mou...Umbilical - Incisional - Diaphragmatic
liver
Alcoholic
liver disease - Cholestasis - Hepatitis - ...
Hy's Law
... Hy's law is prognostic indicator that a pure Drug -Induced
liver Injury (DILI) leading to jaundice, without a hepatic transplant , has a c... is based on observations by Hy Zimmerman , a major scholar of drug-induced
liver injury. [1]
References
^ fda.gov
...
Liver in Medical Dictionary
Liver
Current and accurate information for patients about RFA (for
Liver Tumors). Learn what you might experience, how to prepare for the exam, benefits, risks and more.
Liver disease overview, including information on fatty
liver , hepatitis and cirrhosis, from YourTotalHealth. ... About l...
Fatty liver
Fatty
liver , also known as fatty
liver disease (FLD), steatorrhoeic hepatosis, or steatosis hepatitis, is a reversible condition where large vacuoles of triglyceride fat accumulate in
liver cells via the process of steatosis.... ... the American
Liver Foundation. ... Fatty
liver ...
Yellow Fever
...d a Flavivirus. ... Yellow fever is caused by a small virus that is spread by ... A person with advanced yellow fever may show signs of
liver failure, renal failure, and shock. ... Yellow fever information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient sto...
Wilson disease
...fests as neurological or psychiatric symptoms and
liver disease . It is treated with... Describes th...Wilson disease cannot release copper from. the
liver at a normal rate, due to a muta ... Wilson's...ssive trait. ... The Web Site of the American
liver Foundation. ... Wilson Disease , Genetic Disord...
VLDL
...ajor groups of lipoproteins that enable fats and cholesterol to move within the water-based solution of the bloodstream. VLDL is assembled in the
liver from... Like LDL cholesterol, very-low-density lipoprotein ( VLDL ) cholesterol is considered a type of ... VLDL contains the highest amoun...
Vitamin K
...ized in sufficient quantities by an organism, and must be obtained from the diet.... Vitamin K is an essential nutrient that is needed by the
liver in order to form proteins that promote blood clotting and prevent abnormal bleeding. Non-profit foundation providing reliable, scientifically a...
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Liver in Biological News
Scientists link immune system's natural killer cells to infant liver disease
CINCINNATI Scientists have linked an overactive response by one of the immune system's key weapons against infection natural killer, or NK, cells to the onset of biliary atresia in infants, a disease where blocked bile ducts can cause severe
liver damage and death.
Researchers at Cincinnati ...
Trio of signals converge to induce liver and pancreas cell development in the embryo
PHILADELPHIA - Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies. With regenerated cells, researchers hope to one day fill the acute shortage ...
International Serious Adverse Events Consortium announces initial study results in its global research collaboration to identify genetic markers related to drug induced liver injury
Chicago (June 1, 2009) The International Serious Adverse Events Consortium (SAEC) announced today initial results from its research designed to discover genetic markers that may predict individuals at risk for serious drug induced
liver injury (DILI). The SAEC is a nonprofit research corporation...
New link in liver cancer
Liver damage can be triggered by various insults, including hepatitis infection or alcohol-induced cirrhosis. In severe cases, this damage can lead to cancer. A new study by researchers at the National Institutes of Health and Osaka University reveals how one protein helps decide the fate of damag...
Difference in fat storage may explain lower rate of liver disease in African-Americans
DALLAS March 27, 2009 Where different ethnic groups store fat in their bodies may account for differences in the likelihood they'll develop insulin resistance and non-alcoholic fatty
liver disease, researchers at UT Southwestern Medical Center have found.
According to research reported in th...
Researchers identify gene linked to aggressive progression of liver cancer
RICHMOND, Va. (Feb. 17, 2009) Virginia Commonwealth University researchers have identified a gene that plays a key role in regulating
liver cancer progression, a discovery that could one day lead to new targeted therapeutic strategies to fight the highly aggressive disease.
Hepatocellular carc...
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Liver in Biological Technology
Study Finds Noninvasive Blood Test for Liver Fibrosis May Alleviate Need for Liver Biopsies for Some Patients with Chronic Hepatitis C
MADISON, N.J., June 8 /PRNewswire-FirstCall/ -- A study in the June issue of Clinical Gastroenterology and Hepatology , published by Elsevier, demonstrates that the Hepascore(TM)
liver fibrosis blood-serum test panel may help physicians more accurately diagnose and stage
liver fibrosis in patie...
Ocera Therapeutics Presents Data on AST-120 in Patients With Hepatic Encephalopathy at the European Association for the Study of Liver Disease Annual Meeting
The Company also Initiates the Phase 2b ASTUTE Clinical Trial for Mild Hepatic Encephalopathy
SAN DIEGO, April 28 /PRNewswire/ -- Ocera Therapeutics, Inc., a privately held biopharmaceutical company, announced that data from its phase 2 study of AST-120 for the treatment of patients with low-...
Idenix Announces Data Presentations from Three HCV Discovery and Development Programs at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL)
CAMBRIDGE, Mass., March 18 /PRNewswire-FirstCall/ -- Idenix Pharmaceuticals, Inc. (Nasdaq: IDIX ), a biopharmaceutical company engaged in the discovery and development of drugs for the treatment of human viral diseases, today announced that four abstracts from the company's hepatitis C antiviral...
INFORM-1 Interim Results Accepted for Late-Breaker Presentation at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL)
-- Results from first low-dose cohorts plus data from subsequent higher-dose cohorts to be presented at EASL --
BRISBANE, Calif., March 18 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN ) today announced that an abstract from the clinical study of ITMN-191 (R7227) in combinatio...
Stem Cell Innovations' PluriCells(TM) to Form the Basis of a Liver Assist Device to Support Patients Waiting for Transplant.
HOUSTON, Feb. 5 /PRNewswire-FirstCall/ -- In a paper published in the most recent issue of Current Gastroenterology Reports, Drs. Norman L. Sussman, Brendan M. McGuire and James H. Kelly describe the need and requirements for a successful
liver assist device. "There are currently three times as ...
Intensive Lifestyle Intervention Program for Overweight or Obese Patients with Nonalcoholic Steatohepatitis Reduces Weight and Improves Overall Liver Health
Research to be presented Sunday, November 2, 2008 at this year's
liver meeting in San Francisco, California, October 31 - November 4
SAN FRANCISCO, Oct. 27 /PRNewswire/ -- Nonalcoholic steatohepatitis
(NASH) is strongly associated with obesity, and there is no approved
medical therapy for...
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Liver in Biological Products
Calf Liver tRNA from Novagen
Description: Novagen's Calf
Liver tRNA is qualified for use in reticulocyte lysates for in vitro translation, and is the same supplement used in the Red Nova Lysate ....
Company:Novagen
Anti-G Protein Gq / 11a Subunit, Internal Sequence, a.a. 115-133 Polyclonal Antibody, Unconjugated from CHEMICON
Description:... Recognizes the 41 and 43 kDa G-proteins present in
liver plasma membranes and Gq/11alpha expressed in the Sf9 insect cell expression system. Negative for recombinant G(I)alpha subtypes....
Company:CHEMICON
Chicken Anti-DCTD (dCMP deaminase) Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.
Description:...eukemia; Pregnancy; Herpesviruses; Adenocarcinoma;
liver Cancer; Lung Cancer; Lung Tumor; Lung Diseases; He...; Plasma; Bone Marrow; Fibroblast; T-Cell; Tonsil;
liver Cancer;
liver Tumor; Lymphoid; Ovary; Pharynx; Nucleus; Chromoso...
Company:GenWay Biotech, Inc.
Rabbit Anti-ZO-1 (N-term) Monoclonal Antibody,, Clone ZMD.437 from Invitrogen
Description:...the N-terminus of the ~225 kDa ZO-1 protein. Reactivity: Human Dog Rat Mouse (positive controls: MDCK-II A431 Caco-2 Rat-1 NRK-52E cells frozen mouse
liver heart blood vessel and brain mossy fiber terminal tissues Human pancreas prostate and small intestine tissues). Applications: Western blotting Immuno...
Company:Invitrogen
Total Protein - Alzheimer's Disease: Brain: Pons from BioChain
Description:... Total Proteins from over 50 different human Alzheimer, Diabetic,
liver Cirrhosis, and Lupus diseased tissues are available....
Company:BioChain
Total Protein - Diabetic Disease: Small Intestine: Jejunum from BioChain
Description:... Total Proteins from over 50 different human Alzheimer, Diabetic,
liver Cirrhosis, and Lupus diseased tissues are available....
Company:BioChain
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Liver in Biological Definition
Liver
The
liver is an organ in vertebrates including humans. It plays a major role in metabolism and has a number of functions in the body including detoxification, glycogen storage and plasma protein synthesis. It also produces bile which is important for digestion. Medical terms related...
Alcohol
...re or death and with chronic use can cause severe health problems, such as
liver and brain damage.
Other alcohols are substantially more poisonous than...hol , for instance, is oxidized by alcohol dehydrogenase enzymes in the
liver to the poisonous formaldehyde , which can cause blindness or death. Intere...
Albumin
... white.
Albumin is a blood plasma protein that is produced in the
liver and forms a large proportion of all plasma protein. It is also found in e...)
Buffers pH
Causes of albumin deficiency:
Cirrhosis of the
liver (most commonly)
Decreased production (as in starvation)
Excess excret...
Ames test
... simply kill the bacterial culture in which case a "thin lawn" is observed.
S-9
In some Ames assays an S-9 mix is added. The S-9 mix contains
liver enzymes , generally from a rat. These enzymes can metabolize the agent being tested in order to predict the mutagenic properties within a living syst...
Anatomy
...s :
Anus
Appendix
Brain
Breast
Colon or large intestine
Diaphragm
Ear
Eye
Heart
Kidney
Labia
Larynx
liver
Lung
Nose
Ovary
Pharynx
Pancreas
Penis
Placenta
Rectum
Skin
Small intestine
Spleen
Stomach
Tongue ...
Blood
...ducts, drugs and other foreign chemicals to the
liver to be degraded and to the kidney to be excreted...ceous component is produced overwhelmingly in the
liver , while hormones are produced by the endocrine gl... spleen and the Kuppfer cells in the liver. The
liver also clears proteins and amino acids (the kidney...
Liver in Biological Dictionary
Liver
The
liver is a vital organ present in vertebrates and some other animals; it has a wide range of functions, a few of which are detoxification, protein synthesis, and production of biochemicals necessary for digestion. The...
Liver disease is a broad term describing any single number of...
Yellow fever
...e alternate name ... Yellow fever is caused by a small virus that is spread by ... A person with advanced yellow fever may show signs of
liver failure, renal failure, and shock. ... To identify cases of yellow fever associated with travel and prevent further spread of the ... helps ...
Venules
...us with venules . Venules pool together to form larger ... Abstract and Introduction: Hepatic vein thrombosis should be suspected when ascites,
liver enlargement, ... occlusion of hepatic venules to fatal Budd-Chiari ... ... venous system contains small vessels, venules , which branch toget...
Uric acid
...acid in a urine sample that is collected over 24 hours. ... have slightly lower uric acid levels than men. ... Uric acid is made in the
liver and excreted by the kidneys. ... Supersaturated uric acid in the urine (uricosuria) can crystallize to form ... uric acid gout food high...
Urea cycle
...oving ammonia from the blood stream. The urea cycle involves a... urea cycle n. The sequence of chemical reactions that takes place in the
liver and that results in ... Insufficiency of the urea cycle occurs in some genetic ... Linking families, friends and professionals who are dedicat...
Urea
...rea cycle n. The sequence of chemical reactions that takes place in the
liver and that results in ... 3 ATP + 2 H2O urea + Fumarate + 2 ADP + 4 Pi ...... blood that comes from the waste product urea . ... Urea is made in the
liver and passed ... ...