Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...Live Recombinant Adenovirus Vaccine Technique Explored
Researchers at the Johns Hopkins Bloomberg School of Public Health are exploring ways to develop new vaccines for a variety of illnesses using genetically modified adenoviruses, a common cause of respiratory infections. Oral adenovirus vaccines have long been proven to be safe and effective. The researchers believe their process for constructing a replicating live recombinant adenovirus could lea...Research Gives Hope For Liver Damage
Millions of patients suffering from liverdamage (cirrhosis) and failure may benefit from research by theUniversities of Edinburgh and Southampton which may lead to newlife-saving treatments. There is currently no cure for liver cirrhosisand a patient's only hope of survival is to receive a liver transplant.The Edinburgh scientists from the University's Centre for InflammationResearch, in co...New Breast Cancer Test Could Save Lives
A team of researchers at the University of Bristol is developing a revolutionary new test to detect breast cancer at an early stage. If successful, this test will be effective for women of all ages; given that breast cancer is the largest killer of women between the ages of 35-55 in Europe, the test could have a dramatic effect on the number of deaths from this disease. The test, which ut...Interspecies Trial Array 2: N Brain, N Liver, N Muscle, N Kidney from CHEMICON
Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...Hep G2 cell line slides ( human: liver; hepatocellular carcinoma ) from GeneTex
Description:Human Hep G2 cells were cultured in Minimum Essential Medium (Eagle) with 2 mM L-glutamine and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background stain...PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection
Description:PULSin is an innovative reagent for highly efficient transfer of functional proteins to the cytoplasm of living cells. Unlike DNA transfection, with PULSin Protein & Antibody Delivery Reagent the amount and timing of exogenous proteins in cells can be controlled, even lethal proteins can now be studied. Real time function blocking and protein localization studies can now be easily performed u...PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection
Description:Protein/antibody delivery using PULSin may be superior to transfection in some applications. For example, unlike traditional transfection, with PULSin you can study lethal proteins and control the level and time course of proteins in cells. Likewise, delivery of blocking antibodies may provide more information than traditional RNA interference experiments. With PULSin you can target in...PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection
Description:Protein/antibody delivery using PULSin may be superior to transfection in some applications. For example, unlike traditional transfection, with PULSin you can study lethal proteins and control the level and time course of proteins in cells. Likewise, delivery of blocking antibodies may provide more information than traditional RNA interference experiments. With PULSin you can target in...pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins
Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...High-Titer Retroviral Vectors for Gene Delivery
High-TiterRetroviral Vectors for Gene Delivery Stratagene The high-titer retroviral vectors pFB and pFB-Neo can be used with anyMoloney Murine L...Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR Performance
Improve reliability of PCR reactions with Herculase enhanced DNApolymerase Stratagene enhanced DNApolymerase,* a novel enzyme formulation that providessuperior performance in both routine and demanding PCR applications. Previous...Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures
Jochen Meier, Ivonne Strmel, Radu Iosub, Sonja Schmidt, and Rosemarie Grantyn Developmental Physiology, Johannes Mller Institute, Humboldt University Medical School (Charit), Berlin, Germany Efficient delivery of DNA to primary neuronal cell cultures is of critical importance...Blood Cells Capable of Regenerating Liver
Livers can be regenerated using stem cells from blood -- an important discovery that means patients may be able to grow their own liver transplants using bone marrow. This adds to a growing body of evidence that stem cells, known as "master cells" because they can produce a variety of different kinds of cells, might one day be manipulated to create custom-grown organ transplants....Painkillers Do Not Shorten Dying Patients' Lives
According to some British researhers increasing doses of painkillers to ease the agony of terminally ill patients does not shorten their lives.Some health professionals have criticized the practice, comparing it to euthanasia, but doctors at St Christopher's Hospice in London claim patients receiving higher doses of drugs such as morphine live just as long as those who do not. In re...Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery
A test for fetal fibronectin can predict whether a pregnant woman is at risk for early labor and delivery. Those at high risk for pre-term births are women with previous pre-term deliveries, those with multiple gestation pregnancy, and those who suffer from diabetes and/or hypertension. The current approach for finding whether a woman will go into premature labor is the use of a clinical...Glivec - New Hope For CMC Patients
For those unlucky to be afflicted by the deadly chronic myeloid leukemia (CMC) and their near and dear ones, there's some good news. One of the deadliest forms of leukemia - commonly called 'blood cancer' - kills thousands across the globe. Chronic myeloid leukemia was one of the deadliest killers around and still continues to be one. But there's good news. Multinational pharmaceut...Ebola Virus - 'Outbreak' Claims More Lives In Uganda.
The curse of Uganda – the deadly Ebola virus in its latest outbreak has claimed around 156 lives by December 5th according to Health Ministry officials in Kampala. More shocking is the fact that the dead include many health workers including doctors & nurses. But what shocked the nation was the death of Dr. Mathew Zukeviya, who was a prominent doctor spearheading the fight against Ebola...Lacrimal Intubation Set, Olive Tip, 27 gauge, 3/box
Description:Set consist of two 27 gauge, stainless steel probes with Crawford Olive tips. Probes are 11.5 cm (4.5 inches) long with 30.5 cm (12 inches) of flexible tubing (O.D. - 0.60 mm, I.D. - 0.30 mm) attached onto the probe. 3 sets per box....Gills-Welsh Irrigating-Aspirating Cannula with Flat Olive Tip
Description:Left. 23 gauge thin wall irrigation. 25 gauge thin wall aspiration. Angled 20 degree shaft 10 mm from tip to bend. Irrigation tip set 0.5 mm behind aspiration tip. Side taper irrigation-aspiration through hub. Uses 46 cm (18.1 inches) of silicone tubing (N5941 4). Polished finish. Overall lengths excluding hub: 23 mm, 0.9 inches....Topcon IDS-200 Instrument Delivery System
Description:This exciting new product has generated lots of interest, and continues to be one of the most efficient instruments in Ophthalmology and Optometry today. Time Saving benefits any practice. This system can present the auto refractor values directly to the patient. The ultimate in space efficiencyfits comfortably in a 7' X 7' examination room without the need for external projection mirrors....When Volume Matters, Immunoassay Systems Deliver
Although new and innovative technology has enabled more and more laboratory testing to occur at the bedside or physicians office, the central laboratory is hardly threatened with extinction. National volume data suggest that medium and large labs are busier than ever before, and the huge range of their capabilities, gold standard reliability and ability to handle very large volumes of tests a...