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lipoproteins in Medical News

Obese children may have abnormalities of lipoproteins

Childhood obesity may lead to abnormalities in lipoproteins and may lead to cardiovascular problems in children//. High-density lipoproteins (HDL) are good cholesterols that are good for the body, while low-density lipoproteins (LDL) are bad cholesterols and these should not be allowed to ac...

Protein may be strongest indicator of rare lung disease, study shows

...f lung transplantation. The study, led by Brent Kinder, MD, is published in the June 4 edition of the journal Chest . Surfactant proteins are lipoproteins that allow the lungs to stretch and function. These have previously been investigated by UC pulmonary researchers Frank McCormack, MD, and Jeffrey Whi...

JCI online early table of contents: April 13, 2009

...poproteins, molecules that accumulate in regions of blood vessels affected by atherosclerosis. Detailed analysis in mice indicated that NAbs that bind lipoproteins also bind atherosclerotic regions of blood vessels and cells that have died by a process known as apoptosis. The authors therefore suggest that future...

GEN Reports on Strategies to Overcome Blood-Brain Barrier

...n physiology to enable needed molecules to cross the BBB is receptor-mediated transport (RMT). The brain uses RMT to transport proteins, peptides, and lipoproteins that are needed for brain function across the BBB. Examples of biomolecules that are transported into the brain via RMT include insulin, insulin-like ...

Surgical study highlights pros and cons of gastric bypass surgery for severe obesity

...0 per cent and cases of dyslipidaemia abnormal concentrations of lipids or lipoproteins in the blood fell by 77 per cent. However 29 complications were reporte...number of patients with dyslipidaemia abnormal concentrations of lipids or lipoproteins in the blood fell from 39 to nine (from 20 to four in the proximal group a...

Lipoprotein Levels May Predict Women's Hypertension Risk

...udy suggests the link between high blood pressure and lipoprotein may be more important. "This is the first study that examines whether the size of lipoproteins may affect blood pressure in women. Our findings indicate that even before the onset of hypertension, the size of the lipoprotein particles may indica...

Little-Known Fat Can Be a Heartbreaker

...blood-clotting protein. "It's the worst of both worlds," said Goldberg. lipoproteins carry fat through the blood. Sometimes those fats are used for important functions, such as producing cell membranes. But, if you have too much lipoproteins in your blood, those fats can start collecting on your artery walls, eventu...

Men Won't Ask for Directions - Even About Their Health!

...alAge.com also suggests these heart-health tips: -- Pair O.J. with a bowl of oatmeal for breakfast, a proven dynamic duo for stabilizing low-density lipoproteins (LDL) in the blood. -- Avoid soda, which is associated with other eating habits that pack on pounds and undermine heart health. -- Bulk up with fo...

New Calcium Measure Better Predictor of Heart Risks

...s found a strong association between calcium coverage score and diabetes, hypertension and dyslipidemia -- abnormal concentrations of lipids (fats) or lipoproteins in the blood. They also found that calcium coverage score was a better predictor of future cardiac events than just measuring the amount of calcifi...

Coronary calcium distribution tied to heart attack risk

...d heart attack or other cardiac event. The results showed that diabetes, hypertension and dyslipidemia (abnormal concentrations of lipids [fats] or lipoproteins in the blood) were highly associated with calcium coverage score. The study also found that the calcium coverage scorewhich takes into account the loc...
lipoproteins in Medical Technology

Spherix Announces Positive Phase 2 Study Results

...at there will likely be a place for Naturlose in the treatment regime as either a stand-alone or an adjunct therapy. In addition, the effect on serum lipoproteins may lead to a role for Naturlose in the treatment of atherosclerosis and the metabolic syndrome." Phase 2 Study Design This phase 2 single...

Ion Mobility Diagnostic Test from Quest Diagnostics is First to Provide Direct Physical Measurement of Lipoprotein Particles, Cardiovascular Disease Indicators, Study Finds

...oth the size and concentration of a broad range of lipoproteins in blood plasma. Results of the study were publish...am that affect cardiovascular health. High-density lipoproteins (HDL), referred to as "good" cholesterol, promote ...diovascular function, but LDL and very-low density lipoproteins (VLDL), or "bad" cholesterol, may deposit on the w...

Anthera Announces Positive Phase II Clinical Results From A-002 Cardiovascular Disease Trial

...ed on improvements in cholesterol and markers of inflammation." "This trial revealed that A-002 treatment resulted in significant positive changes on lipoproteins and inflammation, major etiological factors that lead to atherosclerosis among cardiovascular patients treated with statins," said Dr. Robert Rosenson...

Aegerion Pharmaceuticals, Inc. Presents Final Results of Phase II Clinical Trials for AEGR-733 at Drugs Affecting Lipid Metabolism (DALM) 2007 Conference

...bnormal lipid levels in the bloodstream). Inhibiting the MTP enzyme reduces blood levels of cholesterol and triglyceride by limiting the production of lipoproteins from the intestine and liver. In the United States alone, nearly 100 million adults have total blood cholesterol values of 200 mg/dL and higher, and 3...

Isis Pharmaceuticals Reports Positive Phase 2 Data for ISIS 301012 in Familial Hypercholesterolemia Patients Presented at ACC

...-lowering therapies and experienced at least 50% further reductions in LDL-cholesterol (LDL-C), with similar effects on apoB and other apoB-containing lipoproteins and triglycerides (TG). A third patient had apoB and LDL-C reductions of 29% and 32%, respectively, after just six weeks of dosing. HDL-cholesterol (H...

Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal

...lyses physically separate and break down lipoproteins. The SPIFE Lipoprotein analyzer (Helena Laboratories) offers lipoprotein phenotypingseparating lipoproteins into alpha, pre-beta and beta lipoproteins, as well as chylomicrons. Beyond identifying risk, a patients lipoprotein distribution also can serv...
lipoproteins in Medical Products

Lipoprint LDL Subfractionation System

Description:...sterol components which are not routinely tested by other methods. The Lipoprint test provides detailed results within the subfractions of low density lipoproteins (LDL). The Lipoprint system is easy to use and can be installed at any clinical or research laboratory....
Company:Quantimetrix Corporation

Pore Gradient Lipoprotein Electrophoresis System (PGGE)

Description:...m (PGGE) is designed to resolve lipoprotein sub-classes such as low density lipoproteins (LDL) and high density lipoproteins (HDL) based on particle size using nondenaturing pore gradient gel electrop...
Company:C.B.S. Scientific Company

HDL Plus Control

Description:... This control is designed to validate HDL cholesterol plus other major lipids, lipoproteins and apolipoprotein testing methods. This control is compatible with most major chemistry analyzers: AU Series, Cobas, Dimension, Hitachi, Synchron and...
Company:Quantimetrix Corporation

HDL-Cholesterol Reagent

Description:... Intended for the in vitro precipitation of very low density and low density lipoproteins in serum or plasma. Single vial, dry powder precipitating reagent. Total cholesterol reagent not included....
Company:Hemagen Diagnostics, Inc.
lipoproteins in Medical Dictionary

VLDL

... lipoprotein made by the liver. VLDL is one of the five major groups of lipoproteins that enable fats and cholesterol to move within the water-based solution ...L ) is one of three ... VLDL stands for very low density lipoprotein. lipoproteins are substances made of cholesterol, ... VLDL is considered a type of bad ...

Lipoprotein

...parameters that have been associated with ... lipoproteins are molecules made of ... a specific type of lip...lled lipoprotein -a, or Lp(a) ... High levels of lipoproteins can increase the risk ... lipoprotein synon...sembly that contains both proteins and lipids ... lipoproteins may be enzymes, proton pumps, ion pumps, or some ...

LDL

...ends to deposit in the ... Because LDL transports cholesterol to the arteries, increased levels are ... This is why cholesterol inside LDL lipoproteins is called bad cholesterol. ... LDL test ("bad" cholesterol) Lipid profile. High blood cholesterol and triglycerides ... However, LDL level...

HDL

... High-density lipoprotein ( HDL ) is one of the five major groups of lipoproteins which enable lipids like cholesterol and triglycerides to be transported within the water based blood stream. In healthy individuals, about thirty...
lipoproteins in Biological News

Trans fats hinder multiple steps in blood flow regulation pathways

...ega-3), which the body needs for a variety of functions, including blood flow regulation. Studies have shown that trans fats also increase low-density lipoproteins (LDLs) in the blood, a factor which some believe contributes to heart disease. Trans fats are associated with increased inflammation in the arterie...

CFI awards $854,098 to University of Montreal and partners

...overnment of Quebec and the private sector. She will study the number of particles that carry cholesterol in the blood, otherwise known as low density lipoproteins (LDL), as a risk factor for insulin resistance and Type 2 diabetes. "My research explores a novel hypothesis that high concentrations of LDL part...

GEN reports on strategies to overcome blood-brain barrier

...n physiology to enable needed molecules to cross the BBB is receptor-mediated transport (RMT). The brain uses RMT to transport proteins, peptides, and lipoproteins that are needed for brain function across the BBB. Examples of biomolecules that are transported into the brain via RMT include insulin, insulin-like ...

LSUHSC awarded patent for compound inhibiting cancer and other diseases

...the growth of cancerous tumors and diseases like diabetic retinopathy, obesity, and psoriasis. Apolipoprotein A-I is the major protein component of lipoproteins water soluble carrier molecules that transport cholesterol through the blood. LSUHSC researchers discovered that it can be used to destroy existing b...

Cigarette after Valentine snuggle deadlier for some

...esearchers zeroed in on CETP, which manages a persons level of high-density lipoproteins (HDL), the good cholesterol. Unlike low-density lipoproteins (LDL), which build up plaque on artery walls and predispose a person to hea...

Mechanism for the in-vivo transport of siRNA

...e binding partners are the well-known cholesterol transporters High Density lipoproteins (HDL) and Low Density lipoproteins (LDL) as well as the albumin (protein) present everywhere in the blood. Wit...

Pistachios lower cholesterol, provide antioxidants

...the blood by 8.4 percent and low-density lipoprotein (LDL), the so-called bad cholesterol, by 11.6 percent. The study also found that non-high density lipoproteins (non-HDL) decreased by 11.2 percent. Non-HDL levels are considered reliable predictors of cardiovascular disease risk. The three-ounce pistachio...

Baby's genes affect mom's cholesterol levels

...er lipoprotein levels. Because increased levels of lipoproteins can lead to pre-eclampsia and pancreatitis in preg...s. "In pregnant women, the concentrations of these lipoproteins are particularly very high and it is thought that these lipoproteins are the forms that carry the lipids to the placent...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

... used to cook french fries and other fast food. Studies have shown that trans fats not only raise LDL levels in the bloodstream but lower high-density lipoproteins (HDL, or "good" cholesterol) and may have even stronger adverse effects than do saturated fats. The researchers report that when activated by harmf...
lipoproteins in Biological Technology

Atherotech Receives Patent for ApoB Measurement

...ion apoB results. The VAP Test is the only single cholesterol test that routinely reports apoB. ApoB is a protein found on all atherogenic (bad) lipoproteins present in blood circulation, and elevated apoB values represent increased risk for heart disease. In numerous well-designed prospective studies, apoB...

VAP Test Demonstrates Value of Fish Oil in Reducing Heart Risk for Super Bowl Champs

... EPA/DHA omega-3 fatty acid supplements in the form of fish oil soft gels. Results showed that the omega-3 oil raised the athletes' high-density lipoproteins (HDL--good cholesterol) and lowered triglycerides and other atherogenic subfractions. Elevated levels of triglycerides are associated with diabetes an...

Traditional Risk Factors Often Miss Heart Disease Warning Signs

...verlooked emerging risk factor was high levels of triglyceride rich remnant lipoproteins such as IDL (intermediate density lipoproteins) and very low density lipoproteins (VLDL(3)). Low HDL(2) was present in 72 percent of the study group, and hi...

Corgenix Receives Two Additional Patents on AtherOx(R) Technology

...lexes in biological samples. The latest patents add to previous US patents (# 5,900,359 issued May 4, 1999, Method for Determination of Oxidized lipoproteins and Use Thereof ; # 7,160,733 issued January 9, 2007, Ligand Specific to B2-glycoprotein I and Use Thereof; and # 7,422,864 issued September 9, 2008...

Corgenix Receives Third U.S. Patent on AtherOx(R) Technology

...J Lipid Res 2007; 48:768-781). The latest patent adds to previous U.S. patents (# 5,900,359 issued May 4, 1999, Method for Determination of Oxidized lipoproteins and Use Thereof, and # 7,160,733 issued January 9, 2007, Ligand Specific to B2-glycoprotein I and Use Thereof. These patents described the specific in...

Atherotech VAP Cholesterol Test Meets Updated ADA, ACC Measurement and Treatment Guidelines for High Risk Patients

... convened a consensus conference in association with the American College of Cardiology (ACC) and has issued updated guidelines for the measurement of lipoproteins such as LDL, HDL, non-HDL and apoB in CMR patients. "Doctors treating patients with cardiometabolic risk now have clear guidelines to follow, includ...

Anthera Presents Data on Varespladib at ATVB Meeting

...or the treatment of coronary heart disease. Posters include: -- Effects of a Selective Secretory Phospholipase A2 Inhibitor on Low-Density lipoproteins in CHD Patients with Diabetes. -- The Synergistic Inhibition of Atherogenesis in ApoE-/- Mice Between Pravastatin and the sPLA2 Inhibitor Varespl...

Mechanism for the in-vivo transport of siRNA

...e binding partners are the well-known cholesterol transporters High Density lipoproteins (HDL) and Low Density lipoproteins (LDL) as well as the albumin (protein) present everywhere in the blood. Wit...
lipoproteins in Biological Products

Oxidized LDL EIA Kit from Alpco Diagnostics

Description:...L Competitive Enzyme-Linked Immunosorbent Assay (ELISA) kit is intended to be used for the in vitro quantitative determination of oxidized low density lipoproteins (oxidized LDL) in human blood plasma. Lipoprotein measurements are used in t...
Company:Alpco Diagnostics
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