Scientists identify genetic pathways essential to RNA interference
A research team based at Massachusetts General Hospital (MGH) has identified 80 new genes essential to the process of RNA interference (RNAi), a powerful new research tool for inactivating genes in plants or animals. They used the RNAi process itself to find new genes that participate in the gene-silencing mechanism, which someday may help to fight human disease. The report will appear in the jou...Silence the gene, save the cell: RNA interference as promising therapy for ALS
Scientists at the Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have used RNA interference in transgenic mice to silence a mutated gene that causes inherited cases of amytrophic lateral sclerosis (ALS), substantially delaying both the onset and the progression rate of the fatal motor neuron disease. Their results will be published in the April issue of Nature Medicine, and in the...Scientists identify genetic pathways essential to RNA interference
A research team based at Massachusetts General Hospital (MGH) has identified 80 new genes essential to the process of RNA interference (RNAi), a powerful new research tool for inactivating genes in plants or animals. They used the RNAi process itself to find new genes that participate in the gene-silencing mechanism, which someday may help to fight human disease. The report will appear in the jou...Used in a new way, RNA interference permanently silences key breast cancer gene
In laboratory mouse experiments, researchers at The University of Texas M. D. Anderson Cancer Center have developed a way to use RNA interference (RNAi) so that it permanently hampers breast cancer development. The technique permanently silences activated STAT3, a crucial gene found in some human breast tumors, thus reducing the cancer's ability to become invasive. The study, presented at...RNA interference stops colon cancer spread in mice
Using one of the newest and most powerful tools of biomedical science, University of Texas Medical Branch at Galveston (UTMB) researchers have scored a dramatic success in the battle against colorectal cancer. The scientists were the first to use what are known as "small interfering RNAs" to block the spread of human colorectal cancer cells implanted in laboratory mice. Small interfering R...RNA Interference and Gene Silencing: History and Overview
May 20, 2002 Post-transcriptional gene silencing (PTGS), which was initially considered a bizarre phenomenon limited to petunias and a few other plant species, is now one of the hottest topics in molecular biology (<A href="#1">1 ). In the last few years, it has become clear that PTGS occurs in both plants...More siRNA Vectors for RNA Interference
Small Interfering RNAs (siRNAs) are short, double-stranded RNA molecules that can target complementary mRNAs for degradation via a cellular process termed RNA interference (RNAi) (Elbashir et al., 2001a). Recent publications have described the use of vectors expressing functional siRNAs to enable long-term...Interference helps Heart Patients
According to a study, intervention as simple as phone calls from a nurse can help keep heart-failure patients out of the hospital and significantly lower their medical costs.// The study involved 300 patients who were followed for six months after being sent home from two hospitals in the San Diego-based Sharp HealthCare network. Patients received either usual follow-up care or printed...Health Ministry’s Interference in AIIMS Could Prove Deleteriou
Most of India’s health ministers have been unable to resist the allure of the All India Institute of Medical Sciences and the present health minister, Anbumani Ramadoss// , is no different, in fact only worse in this matter. His inability to honor the institutes’ autonomy seems to be particularly acute. Ramadoss has used AIIMS as a site for variegated assertions, the most recent one bei...Understanding HIV Interference With Infected Cell Division
Montreal, July 12, 2007 Dr. Eric A. Cohen, a researcher at the IRCM (Institut de recherches cliniques de Montreal), and his team will publish on Friday, July 13, in PLoS Pathogens a discovery that could lead to the development of a new class of drugs to combat HIV. Human immunodeficiency virus type 1 (HIV-1) causes AIDS by depleting essential immune cells called CD4+T lymphocytes...PHANTOM Absorbable Cannulated Interference Screws
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