Injury

UNC launches study of liver injury caused by drugs

The University of North Carolina at Chapel Hill is one of five clinical centers nationwide to receive funds from the National Institutes of Health to study why good medications are sometimes bad for the liver. During the next seven years, the Drug-Induced Liver Injury Network, or DILIN, will study patients who have suffered severe liver injury caused by prescription and over-the-counter m...

Brain-injury rehabilitation depends on acetylcholine circuitry

The ability of the brain to recover from such injury as stroke or trauma depends on a particular circuitry of neurons that "talk" to one another using the brain chemical acetylcholine, researchers led by James Conner and Mark Tuszynski in the Neural repair Group at UCSD have discovered. Their finding in rats could help enhance rehabilitation to recover from such injuries by leading to the develop...

Stem cell treatment improves mobility after spinal cord injury

A treatment derived from human embryonic stem cells improves mobility in rats with spinal cord injuries, providing the first physical evidence that the therapeutic use of these cells can help restore motor skills lost from acute spinal cord tissue damage. Hans Keirstead and his colleagues in the Reeve-Irvine Research Center at UC Irvine have found that a human embryonic stem cell-derived t...

Combination therapy leads to partial recovery from spinal cord injury in rats

Combining partially differentiated stem cells with gene therapy can promote the growth of new "insulation" around nerve fibers in the damaged spinal cords of rats, a new study shows. The treatment, which mimics the activity of two nerve growth factors, also improves the animals' motor function and electrical conduction from the brain to the leg muscles. The finding may eventually lead to new ways...

Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids

A first-of-its-kind multi-center trial has shown that cooling the body can have positive affects on children who suffered traumatic brain injury. The study's lead investigator, Children's Hospital of Pittsburgh neurosurgeon P. David Adelson, MD, and fellow researchers determined that induced moderate hypothermia initiated after severe traumatic brain injury (TBI) is a safe therapeutic inte...

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Back injury cured by engineers

According to engineers at Cleavland University, people with back injury use the wrong muscles and thereby put themselves at risk of further problems. Back injury is a common problem. People who have had a back problem tend to find it recurs. Researchers at the Biodynamics Laboratory have found that this is because they tend to protect their injury by creating a big stress on their spine afterward...

Recovery from lung injury

According to researchers older people have a less chance of surviving lung injury. But recovery is possible if ventilator treatment is given in time. On an average older people are more susceptible to lung problems that leave them needing the help of a ventilator.// What's not been clear is whether they do as well with treatment as those who are younger. A new study suggests that age is indeed a...

Alzheimer's followed by head injury

Research carried out in England has buttressed the suggestion that head injuries may be linked to the onset of Alzheimer's disease.Doctors at the National Institute on Aging in the UK have analysed the cases of soldiers who suffered head injuries// during World War II. They found that those who suffered moderate head injuries were twice as likely to develop Alzheimer's while those who...

Vitamins suppress artery injury after transplant

According to a new study, Vitamin C and E supplements protect the coronary arteries from narrowing after heart transplant. Heart transplantation can be a life-saver// but, the vessels linking the new heart let the patient down by becoming blocked. If only a way could be found of blocking this process known clinically as arteriosclerosis. Now doctors at The Hopkins Hospital in Boston, US, believe...

New methods to prevent injury of patients

According to researchers at the Hopkins University, Dallas, new ways should be adopted for patients' safety in hospitals. You can get injured in hospital, just as you can on the road and it may be that some of the more recent approaches to road safety can help people in hospital too.// Doctors at the Hopkins University suggest that what's needed is an approach which concentrates on the context of...

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Clinical Trial Suggests Bone Marrow Stem Cells Are Useful for Spinal Cord Injury; PrimeCell Therapeutics Provided Pre-Clinical Study

SYDNEY, Australia--(BUSINESS WIRE)--Jun 27, 2007 - PrimeCell(TM)Therapeutics LLC (http://www.primecelltherapeutics.com) todayannounced that it provided research support and pre-clinicalstudies for a clinical trial to assess the safety, feasibility andefficacy of implanting autologous bone marrow stem cells intospinal cord injury (SCI) patients. Dr. Luis Geffner presented a preliminary rep...

Research Indicates Geron's Human Embryonic Stem Cell-Based Therapeutic for Spinal Cord Injury Evades Direct Attack by the Human Immune System

MENLO PARK, Calif.--(BUSINESS WIRE)--Jun 11, 2007 - GeronCorporation (Nasdaq:GERN) today announced the presentation ofresearch studies indicating that GRNOPC1, the company's humanembryonic stem cell (hESC)-based therapeutic for the treatment ofspinal cord injury, evades a direct attack by the human immunesystem. Presented by Geron scientist Ross Okamura at the Federation ofClinical Immun...

Positive Statistical Analysis from Synthetic Blood's Oxycyte Traumatic Brain Injury Trial Indicates Achievement of Primary Endpoint

COSTA MESA, Calif.--(BUSINESS WIRE)--May 15, 2007 - Synthetic BloodInternational, Inc. (OTCBB:SYBD) today announced positive data froma statistical analysis of its Phase IIa study with Oxycyte(TM) inpatients with traumatic brain injury. In line with preliminarystudy results announced in December 2006, statistical resultsconfirmed that the primary endpoint of increasing patients' oxygentensi...

Inotek Pharmaceuticals Announces Publication of Animal Data from Study of PARP Inhibition as Potential Preventative of Brain Injury Following Stroke

BEVERLY, Mass.--(BUSINESS WIRE)--Apr 10, 2007 - InotekPharmaceuticals Corporation announced today the publication in thejournal Stroke of preclinical animal data showing that theadministration of a poly(ADP-Ribose) polymerase (PARP) inhibitorhas a large protective effect on the survival of certain braincells following a stroke. PARP is a nuclear enzyme that directs therepair of damaged DNA...

Injury at Medicine Dictionary

Traumatic Brain Injury

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Spinal Cord Injury

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Repetitive Strain Injury

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