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inhibit in Medical News

Lab Study Finds Protein That May Inhibit Cancer Spread

Tests in mice show prosaposin injections reduce tumor growth MONDAY, June 22 (HealthDay News) -- A protein produced by certain kinds of tumors inhibits the spread of cancer and could potentially be harnessed as a cancer treatment, researchers say. Currently, there is no approved the...

Newly Identified Compounds May Inhibit Strep Infection

Discovery shows promise for reducing bacterial growth FRIDAY, May 1 (HealthDay News) -- Six compounds that may help fight strep infections have been identified by U.S. researchers. Antibiotic resistance is becoming more common among infection-causing bacteria, researchers have warne...

Vegetable-based drug could inhibit melanoma

Compounds extracted from green vegetables such as broccoli and cabbage could be a potent drug against melanoma, according to cancer researchers. Tests on mice suggest that these compounds, when combined with selenium, target tumors more safely and effectively than conventional therapy. "There a...

Dry beans inhibit development of mammary cancer

Madison, WI, February 2, 2009 - As the world seeks new ways to prevent and treat chronic diseases such as diabetes, heart disease and cancer, more research continues to be conducted on the benefits of certain foods in reducing people's risk of contracting these ailments. Legumes in particular are ...

Statin Use Doesn't Inhibit Lymphoma Drug Therapy

Cholesterol-lowering meds may actually help patients on rituximab, study suggests TUESDAY, Dec. 9 (HealthDay News) -- Cholesterol-lowering statin drugs don't interfere with rituximab, a medication used to treat lymphomas, say Mayo Clinic researchers, who also found that statins may act...

University of Illinois - Chicago Study: Raisins Contain Compounds that May Inhibit Cavity-causing Bacteria

CHICAGO, Oct. 27 /PRNewswire/ -- New research published in the journal, Phytochemistry Letters, reveals raisins may benefit oral health because the fruit possesses antimicrobial phytochemicals that suppress growth of some oral bacteria associated with dental cavities and gum disease. The study...

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inhibit in Medical Technology

SCH 530348 (TRA), a Novel Investigational Antiplatelet Agent, Shown to Inhibit Platelet Aggregation in PCI Patients

Inhibition Was Sustained and Dose-Dependent in Sub-Analysis of Phase II TRA- PCI Trial ORLANDO, Fla., Nov. 7 /PRNewswire-FirstCall/ -- SCH 530348 (TRA), the novel investigational antiplatelet agent in development by Schering-Plough Corporation (NYSE: SGP ), was sho...

Furamidine Found to Inhibit a Key Enzyme Involved in Cancer Cell DNA Repair Mechanisms

NEW YORK, Aug. 14 /PRNewswire-FirstCall/ -- Immtech Pharmaceuticals, Inc. (Amex: IMM ) commented today on a recent paper published in Nucleic Acids Research by a group of researchers at the National Cancer Institute on the ability of furamidine to inhibit a key enzyme involved in the DNA repa...

RTA 402 Shown to Inhibit STAT3 in Animal Model and Holds Significant Promise for Treating Breast Cancer

IRVING, Texas--(BUSINESS WIRE)--May 15, 2007 - Reata Pharmaceuticals, Inc. today announced the publication of an article in the May 2007 issue of the journal Cancer Research showing that RTA 402, the company's Phase 2 development candidate for cancer, was highly effective in a rigorous animal model...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...ated prominently in several scientific conferences, including ASCO and ADA, highlighting the versatility and broad applicability of antisense drugs to inhibit targets that could offer new avenues to treat disease, including cancer and type 2 diabetes. In addition to our clinical programs, we have active pro...

Nektar Therapeutics Reports Second Quarter 2009 Financial Results

...y platform with naloxol, a derivative of the opioid-antagonist drug, naloxone. Nektar's technology has been shown to increase oral bioavailability and inhibit penetration across the blood-brain barrier, an important potential advance for small molecule therapies. The product is being developed to treat opioi...

Cytokine PharmaSciences Initiates Phase I Study of Oral Anti-Inflammatory Agent, CPSI-2364

...ss of efficacy over time." CPSI-2364 is a chemically-modified form of the synthetic guanylhydrozone, semapimod. Semapimod has been shown to inhibit the signal transduction pathways that lead to the production of nitric oxide and important pro-inflammatory cytokines, including TNF-alpha, IL-1, IL-6...

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inhibit in Medical Products

CSK-81®

Description:... deposits from delicate and micro instruments. CSK-81 helps pivot points, box joints and moving instrument parts function better. Use routinely to inhibit new rust and extend the life of your instruments. Simply soak your surgical instruments and CSK-81 will do the rest!...
Company:Instrument Specialists, Inc.

Ghrelin, Total ELISA Test

Description:... of leptin resistance in obesity remains to be elucidated. In addiction, the development of a Ghrelin antagonist, or the development of a mechanism to inhibit Ghrelin release to control appetite may be an important pharmaceutical development for the management of obesity. Finally, recent evidence suggest...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin AB ELISA Test

Description:...sisting of a common a-subunit linked to either a A subunit (Inhibin A) or B subunit (Inhibin B) by disulfide bridges, and in contrast to the Activins, inhibit FSH release. Messenger RNA studies demonstrate that both Inhibin and Activin are most abundant in the ovary and testis, but can be found in a variety...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin A ELISA Test

Description:...sisting of a common a-subunit linked to either a A subunit (Inhibin A) or B subunit (Inhibin B) by disulfide bridges, and in contrast to the Activins, inhibit FSH release. Messenger RNA studies demonstrate that both Inhibin and Activin are most abundant in the ovary and testis, but can be found in a variety...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin B ELISA Test

Description:...sisting of a common a-subunit linked to either a A subunit (Inhibin A) or B subunit (Inhibin B) by disulfide bridges, and in contrast to the Activins, inhibit FSH release. Messenger RNA studies demonstrate that both Inhibin and Activin are most abundant in the ovary and testis, but can be found in a variety...
Company:Diagnostic Systems Laboratories, Inc.

IGFBP-1, Total IRMA Test

Description:... of its regulation suggests that IGFBP-1 may be involved in glucose regulation and IGF-mediated substrate utilization [1,2]. IGFBP-1 has been shown to inhibit [3,4] as well as augment [5,6] IGF bioactivity. These paradoxical reports may be due to differential phosphorylation of IGFBP-1 which may significantl...
Company:Diagnostic Systems Laboratories, Inc.

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inhibit in Medical Dictionary

Norepinephrine

..... Infuse norepinephrine through a large stable vein to avoid tissue necrosis ... Norepinephrine acts at presynaptic alpha2 receptors to inhibit its own release. ... There is very limited clincial use of norepinephrine . ... ... such as dopamine or norepinephrine , generally have fewer si...

LSD

...t potent mood ... The effects of LSD are unpredictable. ... A sculptor attending an LSD party in Detroit (above left) is ... LSD is known to inhibit ... Cats on high dosages of LSD for a three-week period ... ...

Laser therapy

...herapy is an emerging medical and veterinary technique in which exposure to low-level laser light or light-emitting diodes are used to stimulate or inhibit cellular function possibly leading to beneficial clinical effects. The technique is also known by... What is laser therapy ? ... Laser thera...

Immunosuppressant drugs

... Immunosuppressive drugs or immunosuppressive agents are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: More about Immunosuppressant Drugs : Purpose Recomme...

Drug Resistance

... is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is... Drug resistance . Raising awarenes...

Clot

... forms in a vein deep ... If a clot in a vein breaks off and travels through your bloodstream, it can ... the clot from ... Anticoagulants inhibit the ability of blood to clot , or coagulate. ... existing blood clots . They prevent new clots from forming or existing clots from getting ....
inhibit in Biological News

Scripps research team identifies key molecules that inhibit viral production

The research, led by Professor Donny Strosberg of Scripps Florida, was published on March 4, 2009, in the Journal of General Virology 's advance, online edition, Papers in Press. In the new study, Strosberg and his colleagues describe peptides (molecules of two or more amino acids) derived fr...

Soy isoflavone may inhibit common gastrointestinal illness in infants

The soy isoflavone genistin--at concentrations present in soy infant formula-- may reduce a babys susceptibility to rotavirus infections by as much as 74 percent, according to a University of Illinois study published in Septembers Journal of Nutrition. Rotavirus is the primary cause of diarrhea...

Targeting sugar on blood vessels may inhibit cancer growth

In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the tumor. Their findings will be published in the May 7 on-line issue...

'Best of both worlds' -- Targeting a single gene could inhibit bone decay and stimulate bone growth

Researchers at the University of Pennsylvania’s School of Medicine have found by targeting the function of a single gene that it is possible to inhibit bone decay while simultaneously stimulating bone formation. This concept may lead to drug treatments for osteoporosis and other bone diseases. Seni...

Vegetables inhibit growth of prostate cancer in mice with human tumors

As long-lived predators at the top of the marine food chain, albatrosses accumulate toxic contaminants such as PCBs, DDT, and mercury in their bodies. A new study has found dramatic differences in contaminant levels between two closely related albatross species that forage in different areas of the...

Scientists inhibit cancer gene

By studying mice with skin cancer, researchers at the Huntsman Cancer Institute at the University of Utah discovered a way to inhibit a mutant gene found in up to 30 percent of human tumors. Called Ras, normal copies of this gene are important in cell signaling, or communication among cells. When...

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inhibit in Biological Technology

LNA-Based RNA oligonucleotides Potently Inhibit Cancer microRNAs

COPENHAGEN, April 20 /PRNewswire/ -- Santaris Pharma announced today promising findings on the in vitro and in vivo activity of microRNA-targeted therapeutics against cancer developed on the basis of its proprietary Locked Nucleic Acid (LNA) Drug Platform. In both in vitro and in vivo models S...

OncoGenex Reports Second Quarter 2009 Financial Results

...hase 2 clinical trials in prostate, lung and breast cancers, is designed to inhibit the production of a specific protein associated with treatment resistance; ...nsed from Isis Pharmaceuticals (NASDAQ: ISIS ), to effectively target and inhibit production of specific proteins in tumor cells. OncoGenex and Isis partnere...

OncoGenex Pharmaceuticals to Release Second Quarter 2009 Financial Results

...cer drug development. OGX-011, the lead candidate that has completed five Phase 2 clinical trials in prostate, lung and breast cancers, is designed to inhibit the production of a specific protein associated with treatment resistance; OGX-427 is in Phase 1 clinical development; SN2310 has completed the Phase ...

Nektar Therapeutics to Present at the BMO Capital Markets 9th Annual Focus on Healthcare Conference in New York City

...y platform with naloxol, a derivative of the opioid-antagonist drug, naloxone. Nektar's technology has been shown to increase oral bioavailability and inhibit penetration across the blood-brain barrier, an important potential advance for small molecule therapies. The product is being developed to treat opioi...

Nektar to Announce Financial Results for the Second Quarter of 2009 on Tuesday, August 4, 2009, After Close of U.S.-Based Financial Markets

...y platform with naloxol, a derivative of the opioid-antagonist drug, naloxone. Nektar's technology has been shown to increase oral bioavailability and inhibit penetration across the blood-brain barrier, an important potential advance for small molecule therapies. The product is being developed to treat opioi...

R-Tech Ueno Notifies R&D Items

... macular degeneration. 2. Development code RTU-007 (eye diseases) The license is obtained from Astellas Pharma Inc. for the substance to inhibit the enzyme that increases in patients with diabetes mellitus. We intend to proceed with the development of this substance to be indicated for diabetic...

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inhibit in Biological Products

Caspase Inhibitor Ac-DEVD-CHO, Unconjugated from Promega

Description:... caspase-3/7 (DEVDase) activity. The concentration of inhibitor required to inhibit caspase activity must be determined empirically for each system. Ten micromolar inhibitor is sufficient to inhibit caspase activity in extracts of apoptotic THP-1 cells....
Company:Promega

13(S)-HODE-d4, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...ODE by GC- or LC-mass spectrometry. 13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian lipoxygenases. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM, and down regulates the expression of the IRGpIIb/IIIa receptor....
Company:Cayman Chemical

13(S)-HODE-d4, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...ODE by GC- or LC-mass spectrometry. 13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian lipoxygenases. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM, and down regulates the expression of the IRGpIIb/IIIa receptor....
Company:Cayman Chemical

Mouse Anti-TATA Binding Proteins (TBP) Monoclonal Antibody, Unconjugated, Clone ITBP20 from Covance Research Products, Inc

Description:...ant human TBP and recognizes amino acids 41-57 and may be useful in applications where N-terminal fragmentation of TBP occurs. This antibody does not inhibit the activity of TBP (prepared either as a nuclear extract or as a minimal activity extract) in a DNA transcription assay. This antibody is effective i...
Company:Covance Research Products, Inc

PARP Inhibitor XI, DR2313 from Calbiochem

Description:...nase activity of GAPDH, ADH, LDH, or the ADP-ribosylase activity of bacterial diphtheria toxin even at concentrations as high as 10 µM. Shown to inhibit H 2 O 2 -induced PAR formation and neuronal cell death in primary rat cerebral cortex culture in vitro (EC 50 = 270 nM) and exhibit neuroprotective...
Company:Calbiochem

Rabbit Anti-Human PHAS-II Polyclonal Antibody, Unconjugated from Lab Vision

Description:...ein II) is involved in translation initiation. PHAS-II is highest in liver and kidney. PHAS proteins bind to eIF-4E, the mRNA cap-binding protein, and inhibit translation of capped mRNA in vitro and in cells. Phosphorylation in the appropriate site(s) promotes dissociation of PHAS/eIF-4E complexes. This allo...
Company:Lab Vision

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inhibit in Biological Definition

Antibiotic

... macrolides Antibiotics which interfere the 30S ribosomal unit Tetracyclines; aminoglycosides including gentamicin Drugs which inhibit folate synthesis Sulfonamides and trimethoprim Drugs which interfere with DNA synthesis Metronidazole, quinolones, novobiocin ...

Cancer

..., has been shown to lower the risk of prostate cancer. Other examples of drugs that show promise for chemoprevention include COX-2 inhibitors (which inhibit a cyclooxygenase enzyme involved in the synthesis of proinflammatory prostaglandins ). Considerable research effort is now devoted to the develop...

Cryptozoology

... has now been discovered), mountain gorilla , and komodo dragon are a few such creatures. Supporters note that unyielding skepticism may in fact inhibit discovery of unknown animals. Others have suggested a rigid World view disallows many academics from accepting evidence contrary to their preconce...

Enzyme

...at serve regulatory functions, which increase or inhibit the enzyme's activity. These typically bind metal...edback inhibition. The end products P 1 and P 2 inhibit the first committed step of their individual pathw... first individual committed step. Together , they inhibit the first common committed step. (5) Cumulative f...

Fermentation

...p food energy and can make conditions unsuitable for undesirable microorganisms. For example, in pickling the acid produced by the dominant bacteria inhibit the growth of all other microorganisms. Fermentated foods, by region World wide: olives , vinegar , wine , yoghurt Asia India: ...

Malaria

...ause malaria. Treatment and prevention If diagnosed early, malaria can be treated, but prevention is always much better, and substances that inhibit the parasite are widely used by visitors to the tropics. Since the 17th century quinine has been the prophylactic of choice for malaria. The devel...
inhibit in Biological Dictionary

Transfer RNA

... research information, and more. ... Total Aminoacyl- Transfer RNA Pool Is Greater ... Messenger RNA . RNA Interference. Protein Destruction. inhibit Protein Expression. MRNA Degradation ... Rna . Search multiple engines for messenger rna . www. ... Transfer RNA and its Interactions with Se...

Transcriptase

...le helix... Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors, and cancer . RTIs inhibit activity of reverse transcriptase , a viral DNA polymerase enzyme that retroviruses need to reproduce. Information about transcriptase in th...

Trans-

... professionals, educators, ... trans fats are "just as bad" as saturated. fats (the kind found in butter, meat fat and the ... Trans fats inhibit the body's use of omega-3. fatty acids and ... Blame it on the trans . ... Because food labels don't have to disclose how much trans a food co...

Trans

... professionals, educators, ... trans fats are "just as bad" as saturated. fats (the kind found in butter, meat fat and the ... Trans fats inhibit the body's use of omega-3. fatty acids and ... Blame it on the trans . ... Because food labels don't have to disclose how much trans a food co...

Syncytium

...ing when one cell contracts, they all ... To test the MAbs' ability to inhibit syncytium formation, 50 μl of K562/VCAM1 ... New MAbs inhibit HTLV-1 syncytium formation. ... ... the envelope V3 domain differ in...

Spermatogenesis

...he male reproductive organs, the ... SPERMATOGENESIS . Spermatogenesis is the process of sperm cell development. ... the X chromosome that inhibit spermatogenesis are inactivated in XY somatic cells. ... Shop for Proteomics of Spermatogenesis - Books at Shop.com. Books|Non-Fiction|Englis...
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