inhibit

Topical treatment shown to inhibit HIV and herpes simplex virus infection

Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina. The study, which was fund...

Novel antiviral technology inhibits RSV infection in mice

A novel antiviral treatment combiningnanoparticle and gene silencing technologies thwarts attacks ofrespiratory syncytial virus (RSV) -- a virus associated with severebronchitis and asthma, an animal study by University of South Floridaresearchers found. The study was reported in the January 2005 issue ofthe journal Nature Medicine.RSV infects lung cells and can be life-threatening in very...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

A widely-used class of drugs that keep the HIV-virus infection from progressing to AIDS may cause serious and potentially lethal heart rhythm disturbances in some patients. The finding of a Mayo Clinic-led investigation appears in the current edition of The Lancet. In collaboration with colleagues from the HIV Program of Hennepin County Medical Center, Minneapolis; the University of Minn...

Breast Cancer May Be 'Uniquely Sensitive' To Inhibitors Of PI3K Pathway

"Because up to 75 percent of breast cancerpatients have an abnormality in a specific cell signaling pathway,drugs that target different molecules along that pathway may beespecially effective for treating the disease, says a researcher fromThe University of Texas M. D. Anderson Cancer Center." A clearer picture is now emergingabout the importance of the phosphatidylinositol 3 kinase...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

A novel delivery system that transports gene silencing nanoparticles into tumor cells has been shown to inhibit Ewing's sarcoma in an animal model of the disease. In this classic "Trojan horse" approach, a protein called transferrin that normally delivers iron into cells is modified to also smuggle into tumor cells siRNA (short interfering RNA) encased in nano-sized sugar polymers. The si...

More>>

inhibit at Biology Products

Mouse Anti-C1-inhibitor (C1-INH) Monoclonal Antibody, Unconjugated, Clone 8F3 from AntibodyShop A/S

Description:C1-inhibitor (C1-INH)...
Company:AntibodyShop A/S

QIAGEN RNase Inhibitor (7500 U) from QIAGEN

Description:For potent inhibition of RNase A-type ribonucleases QIAGEN RNase Inhibitor is a protein of nonhuman origin that binds noncovalently and inactivates a variety of ribonucleases (e.g., RNase A, B, and C). It does not interfere with RNase T1, T2, H, U1, U2, or CL3. QIAGEN RNase Inhibitor inhibits greater than 90% of RNase activity, whereas HPRI (human placental RNase inhibi...
Company:QIAGEN

RNase Inhibitor from Applied Biosystems

Description:RNase Inhibitor (Ribonuclease inhibitor) is a 50 kDa recombinant enzyme used to inhibit RNase activity. It does not contain DNase or endonuclease activity....
Company:Applied Biosystems

Recombinant RNasin^® Ribonuclease Inhibitor from Promega

Description:Natural and Recombinant RNasin Ribonuclease Inhibitors have broad spectrum RNase inhibitory properties, including the inhibition of eukaryotic RNases of the neutral type (1). The 50kDa protein exerts its inhibitory effect by noncovalently binding to RNases in a 1:1 ratio. The Ki value for the binding of RNasin Ribonuclease Inhibitor to RNase (e.g., RNase A) is approximately 1014M (24). Promega of...
Company:Promega

GeneChoice RNA Safe Recombinant Ribonuclease Inhibitor from GeneChoice, Inc.

Description:Ribonuclease Inhibitor is a recombinant protein that has been shown to help maintain the integrity of RNA in the preparation of cDNA by reverse transcription, in vitro RNA transcription, and in vitro protein synthesis. RNA Safe Inhibitor tightly binds RNases in a 1:1 ratio. It inhibits a broad range of eukaryotic RNases such as RNase A, RNase B, RNase C, and human placental RNase. RNA Safe does...
Company:GeneChoice, Inc.

More>>

inhibit at Biology Technology

Decontamination and inhibition of ribonucleases

It is common knowledge in most laboratories that RNA is more susceptible to degradation than DNA. Unlike Deoxyribonucleases (DNases), which require metal ions for activity (and can therefore easily be inactivated with chelating agents such as EDTA), ribonucleases (RNases) have virtually no cofactor requirements and adv...

Measurement of proteasome inhibition in live cells in Molecular Devices microplate fluorometers

Proteins inside eukaryotic cells exist in a dynamic state, in a highly-regulated balance between synthesis and degradation. Whereas prot...

A Microtiter-based Assay for the Determination of ID50s of b-lactamase Inhibitors Employing Reporter Substrates Detected at UV or Visible Wavelengths (MaxLine Application Note #20)

β -lactamases are either plasmid or chromosomally encoded bacterial enzymes which hydrolyze β -lactam antibiotics. The majority of β -lactamases produced by clinical isolates are serine active site enzymes. One successful approach to combating the serine active site β -lactamases is the use of β -lactamase inhibit...

Protector RNase Inhibitor

from rat lung, recombinant Catalog Number Pack Size 3335399 2000 units 3335402 10000 units (5 vials of 2000 U...

Protector RNase Inhibitor Enhance the Protection of RNA against Degradation

Is a new type of RNase inhibitor and inhibits a wide known spectrum ofRNases. Does not interfere with the performance of enzymes in an assay - evenwhen high amounts (e.g., up to 16-fold the standard concentr...

More>>

inhibit at Biology Definition

Selective serotonin reuptake inhibitor

(5-hydroxytryptamine or 5-HT), in the <a href="/ ?q=/ Biology-De...

Competitive inhibitor

: competitive and noncompetitive inhibition. , the molecule acts on the same active site as the normal enzyme <a href...

inhibit at Biology Dictionary

Feedback inhibition

, 2nd Edition. Ne...

Competitive inhibition

<A href="http:/ / en.wikipedia.org/ ...

inhibit at Medicine News

Blood pressure control with ACE inhibitor or diuretic?

An Australian study published in The New England Journal of Medicine has challenged the American ALLHAT trial that showed diuretics were superior to ACE (angiotensin-converting enzyme) inhibitors and calcium channel blockers in controlling blood pressure. The Australian study included 6,083 people who were mostly white. Blood pressure reduction was the same in those who took a diuretic an...

Tomatoes Might Inhibit the Development Of Prostate Cancer

A new study finds that lycopene is not the only compound in tomatoes that could prevent prostate cancer.Lycopene is a carotenoid in tomatoes that gives //them that familiar red color. Research has suggested lycopene could reduce the risk of prostate cancer. But it is unclear if lycopene itself is responsible for the risk reduction. Researchers from the University of Illinois studied th...

Artificially made protein to inhibit angiogenesis

Researchers of Medical College of Georgia had successfully made a protein// that will stop the process of angiogenesis. Angiogenesis is the abnormal growth of blood vessels that may lead to obstructed vision or growth of a tumor. The new protein, when applied to animals suffering from corneal injury or skin cancer called melanoma, reduced the blood vessel proliferation by...

Identified Protein To Inhibit Cell Migration

Researchers from the University of North Carolina have identified a protein that may inhibit cellular movement, or migration. // The protein, CIB1, or calcium and integrin-binding protein 1, was originally discovered at UNC in 1997 as a blood platelet protein that may play a role in clotting. Cell migration belongs to the most rudimentary of cellular functions that allow processes su...

Phase 3 trials of two multi-kinase inhibitors against cancer

Sorafenib and stutent multi-kinase inhibitors against cancer is undergoing phase 3 trials// and these two drugs gained more appreciation in this years ASCO (American Society of Clinical Oncology) conference. This drug is gaining interest due to its multiple mechanism of action – known as Multi-kinase inhibitors. These drugs are in trial against different types of cancer and are found to b...

More>>

inhibit at Medicine Products

Shoulder Subluxation Inhibitor (SSI)

Description:Shoulder Subluxation Inhibitor (SSI) is an ideal bracing system to keep athletes on the field by reducing the risk of shoulder injury. The SSI is the only brace that allows TOTAL ANTERIOR RANGE OR MOTION without subluxation of the shoulder(s)....
Company:Boston Brace International

ADAMTS13 Activity & Inhibitor (VWF Cleaving Protease)

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Bethesda Quantitative Factor VIII, Inhibitor, Quantitative

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

C1 Inhibitor (C1INH)

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

C1-Esterase Inhibitor

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

More>>

inhibit at Medicine Technology

Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis

SAN FRANCISCO, July 10, 2007 /PRNewswire/ -- PortolaPharmaceuticals, Inc. announced positive Phase II data on its leadcompound, PRT054021, an oral Factor Xa inhibitor, today at the XXICongress of the International Society on Thrombosis and Haemostasis(ISTH) in Geneva, Switzerland. The EXPERT trial showed thatPRT054021 was safe, effective, and well tolerated for theprevention of venous th...

Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme

CAMBRIDGE, U.K. 2nd July 2007 - CeNeS Pharmaceuticals (AIM:CEN)("CeNeS" or "the Company") the Cambridge-based biopharmaceuticalcompany today announced that a paper published this week in CNSDrugs(1) further supports the hypothesis that acatechol-O-methyltransferase (COMT) inhibitor that acts in thebrain would be a useful agent to address profound cognitivedeficits in schizophrenia and bi...

Arisaph Pharmaceuticals Announces Results of its Potent Smart DPP-4 Inhibitor, ARI-2243, at the ADA

- ARI-2243 is an highly potent DPP-4 inhibitor, possessing Ki of 27pM BOSTON, June 25, 2007 /PRNewswire/ -- Arisaph Pharmaceuticals,Inc., a privately held drug discovery biopharmaceutical company,announced today the results of its potent, smart DPP-4 inhibitor,ARI-2243, presented at the 67th session of the American DiabetesAssociation meeting in Chicago, Illinois. The results showed that...

Anadys Pharmaceuticals Nominates ANA598, a Small-Molecule, Non-Nucleoside Inhibitor of The NS5b Polymerase, as a Candidate for Clinical Development in Chronic Hepatitis C Virus Infection

SAN DIEGO, June 20, 2007 /PRNewswire-FirstCall/ -- AnadysPharmaceuticals, Inc. , a biopharmaceutical company committed tothe discovery, development and commercialization of novel medicinesfor the treatment of hepatitis and cancer, announced today that ithas nominated ANA598 as a candidate for clinical development as anorally-administered direct antiviral for the treatment of chronichepat...

Ambrilia Highlights Encouraging Data for its HIV Integrase Inhibitor Program and Recent Developments at Annual Meeting

MONTREAL, QUEBEC--(CCNMatthews - June 14, 2007) - AmbriliaBiopharma Inc. (TSX:AMB), a biopharmaceutical company developingnovel small molecules and peptides to treat infectious diseases andcancer, held its Annual General and Special Meeting today, duringwhich the data reported yesterday on its novel series of HIVintegrase inhibitors and recent developments were highlighted. Themeeting wa...

More>>

inhibit at Medicine Definition

Depolarization-induced suppression of inhibition

....