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Past experience of pheromones induces dominant courtship behavior in fruit flies

By investigating the interplay between pheromone signaling and behavior in fruit flies, researchers have begun to understand how an adult fly's earlier experience as a young individual can influence its behavior towards other flies as an adult. In particular, the researchers found that pheromone signals in the context of experience with adult flies can influence how young flies will behave once t...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

Scientists have completed the first human clinical trial of a recombinant vaccine for the deadly toxin ricin ?a potential bioterror threat ?and the results indicate the vaccine is safe and effective in eliciting ricin-neutralizing antibodies, the UT Southwestern Medical Center researchers report. The nearly year-long pilot study involved three groups of five volunteers each. Individuals in...

H5N1 avian flu virus vaccine induces immune responses in healthy adults

Results from a clinical trial demonstrate that high doses of an experimental H5N1 avian influenza vaccine can induce immune responses in healthy adults. Approximately half of those volunteers who received an initial and a booster dose of the highest dosage of the vaccine tested in the trial developed levels of infection-fighting antibodies that current tests predict would neutralize the v...

Radiation-killed bacteria vaccine induces broad immune response in mice

Vaccines made with bacteria killed by gamma irradiation, rather than by standard methods of heat or chemical inactivation, may be more effective, say researchers supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). Vaccines made from gamma-irradiated bacteria also may not need to be kept cold; an advantage in settings whe...

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Antibiotic induces liver damage in children with E.COLI infections.

The strain of bacteria known as E. coli 0157:H7 causes some of the most serious digestive infections in both children and adults. Infections with this organism are often caused by eating undercooked meat. A major study shows using antibiotics to treat children with E. coli bacterial infection increases the risk of developing a potentially deadly liver disorder. "Our data suggests that an...

UV Radiation induces Melanoma

Children who suffer sunburn very early in life are far more likely to suffer the most dangerous form of skin cancer, suggest researchers. In humans, melanocytes, the pigment-producing skin cells where melanoma develops, are on the surface of the skin. It is thought that some melanomas are the result of genetic damage caused when the UV radiation strikes these pigment cells. Babies and you...

High expression of interferon induces lupus disease

Scientists had been able to find a biomarker that will help in medical practitioners to diagnose lupus disease in their early state only for effective treatment.// Lupus is a condition that happens when the body’s tissues are affected by the body’s own immune system. Patients affected with lupus may produce abnormal antibodies in their blood that may attack the body’s own tissues than...

Citrinin, a fungal toxin, induces apoptosis via mitochondrial pathway

The Mycotoxin citrinin (CTN) is a secondary metabolite produced by several fungal species that belong mainly to the genus Penicillium and Monascus. It is widely considered as a hazard contaminant of foods// and feeds, including corn, wheat, rice, barley and nuts, and is known to be cytotoxic and genotoxic to various mammalian cells. CTN has been suggested as a causative factor in renal di...

Plant based fake meat induces repulsive reaction

In a strongly worded news the Centre for Science in the Public Interest, has received more than 130 complaints from British and American consumers// to ban the sale of - the fake meat made from fungus that is sold under the brand name Quorn. It was found to induce vomiting and many people fell ill. Quorn is the brand name for a line of foods made with fungi based 'mycoprotein.' That in...

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EntreMed's Aurora Kinase Inhibitor Induces Tumor Regression in Preclinical Models

ROCKVILLE, Md., June 01, 2007 /PRNewswire-FirstCall/ --EntreMed, Inc. , a clinical-stage pharmaceutical company developingtherapeutics for the treatment of cancer and inflammatory diseases,announced the presentation of preclinical results for its Aurorakinase - angiogenesis inhibitor, ENMD-981693. The data werepresented during oral and poster presentations by EntreMedscientists at the 2n...

Cell Genesys Reports GVAX Immunotherapy for Prostate Cancer Induces a Broad, Patient-Specific Antibody Response

SOUTH SAN FRANCISCO, Calif., April 17, 2007/PRNewswire-FirstCall/ -- Cell Genesys, Inc. today reported immuneresponse data from two previously conducted Phase 2 clinical trialsof GVAX immunotherapy for prostate cancer. Evaluation of antibodyresponses in patients with advanced prostate cancer from thesestudies shows that the GVAX cell-based immunotherapy inducesantibody responses to a bro...