Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
In a finding that broadens our insight intothe cause of certain kinds of UV-induced skin cancer, researchers atErasmus University Medical Center (Rotterdam, The Netherlands) haveemployed an evolutionarily ancient enzyme-repair system to identify theprincipal type of DNA damage responsible for the onset of skin-tumordevelopment. The researchers' findings also suggest that this enzymesystem m...Antibiotic might fight HIV-induced neurological problems
By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body. Five monkeys infected with simian immunodeficiency virus (SIV), a very close relative of HIV, and treated wi...NYU and MSKCC research provides model for understanding chemically induced cancer initiation
A team from the chemistry and biology departments of New York University, in collaboration with Memorial Sloan Kettering Cancer Center (MSKCC), has uncovered a conformational switch--a change in shape in a carcinogen-damaged DNA site--in tumor suppressor genes altered by a known cancer-causing chemical found in cigarette smoke. This finding may open new horizons for understanding the initiation o...Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief
new study shows, for the first time, that the release of the body's own marijuana-like compounds is crucial to stress-induced analgesia ?the body's way of initially shielding pain after a serious injury. The work, led by scientists at the University of Georgia and the University of California, Irvine, may yield a target for new drug therapies that will completely bypass the current argume...Researches discover gene critical for protection against septic-shock-induced death
Disruption of a single gene, Nrf2, plays a critical role in regulating the body's innate immune response to sepsis and septic shock, according to a study by a research team led by Shyam Biswal, PhD, at the Johns Hopkins Bloomberg School of Public Health. The researchers found that the absence of Nrf2 caused a dramatic increase in mortality due to septic shock in mice. The study's findings...RAW 264.7 cell line slides ( mouse: Abelson murine leukemia virus - induced tumor ) from GeneTex
Description:Mouse RAW 264. 7 cells were cultured in DMEM with 4 mM L-glutamine medium and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background staining. Each well i...PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (100X) from Lab Vision
Description:This product is designed to deparaffinize and perform Heat Induced Antigen Retrieval (HIER) on formalin fixed paraffin-embedded tissue sections mounted on glass microscope slides. Deparffinization is accomplished by melting the paraffin at the high temperature used in HIER (over 90degrees C) along with emulsification of the paraffin by detergent. Formaldehyde fixation impairs or totally destroys...PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (10X) from Lab Vision
Description:This product is designed to deparaffinize and perform Heat Induced Antigen Retrieval (HIER) on formalin fixed paraffin-embedded tissue sections mounted on glass microscope slides. Deparffinization is accomplished by melting the paraffin at the high temperature used in HIER (over 90degrees C) along with emulsification of the paraffin by detergent. Formaldehyde fixation impairs or totally destroys...Fast, Accurate Assessment of siRNA-induced Gene Silencing
Cells-to-Signal Kit: Small Sample Prep for qRT-PCR Real-time, quantitative RT-PCR (qRT-PCR) is the most sensitive way to detect and quantitate mRNA and is often used to validate techniques that monitor changes in gene expression, including array analyses and RNA...Aspirin Induced Asthma , A Little-Known Inducer
Aspirin-induced asthma is a severe reaction to aspirin or other painkillers that is characterized by the onset of asthma 30 minutes to three hours // after taking the medications. British researchers analyzed more than 20 studies on asthma and found more than 20 percent of adults and about 5 percent of children suffer from the condition. Researchers say most of these patients were also...Causes of drug induced liver disease
A new study by investigators from Sahlgrenska University Hospital in Gothenburg, Sweden,// had done a study on the factors and outcomes of the health condition called drug-induced liver disease. Drug induced liver disease happens with some medication. Although stops when the medication is withdrawn, some effects of this condition may be requiring liver transplant or can be fatal. An ob...Induced abortion results in years of trauma.
A study on mental agony experienced by women after abortion which was headed by Anne Nordal Broen revealed shocking results. // It showed that the sufferings of the women who had induced abortions were many times higher and extended to longer time periods than those who had miscarriage. The study included women from the Buskerud Hospital in Drammen, who had miscarriage (40) and...Handling skin irritation induced by Radiation Therapy
Radiation therapy is one of the important treatment options for curing breast cancer. Though it is simple and painless one of the most common temporary side effect is skin// irritation. Skin irritation induced by radiotherapy varies from patient to patient. It usually occurs in patients who received chemotherapy shortly before or during radiation therapy. It is also severe among women w...Induced Labor A Danger to both Mother and Baby
According to a research conducted by Elisabeth Erekson, new Saint Louis University it was found that induced labor result in severe complications to both the mother// and the baby. These women suffer from a higher risk of developing chorioamnionitis. It results in an infection which affects the placental tissues and amniotic fluid. The results of her research are to be presented at the annual mee...AquaTherm Water-Induced Thermotherapy (WIT) System
Description:One of the most innovative and elegantly simple alternatives for BPH treatment, Water-Induced Thermotherapy (WIT) provides an ideal solution for physicians seeking to treat patients in the office. No other option provides a better combination of safety, simplicity, and proven outcomes. The AquaTherm System heats, circulates, and maintains precise control of water in a closed-loop catheter system....Heparin-Associated Antibody Detection (Heparin-Induced Thrombocytopenia)
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Opexa Advances Monocyte Derived Islet Technology to Proof of Principle in stz-induced NOD/SCID Mice
THE WOODLANDS, Texas--(BUSINESS WIRE)--Jun 27, 2007 - OpexaTherapeutics, Inc. (NASDAQ:OPXA), a company involved in thedevelopment and commercialization of cell therapies, presentedposter presentations at the 5th International Society for Stem CellResearch Annual Meeting (ISSCR) in Cairns, Queensland, Australiafrom June 17-20 and at the 13th Annual Meeting of the InternationalSociety for Cel...