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Study aims to induce recovery from ankylosing spondylitis

Chinese patients will soon have the opportunity to take part in a study of a novel therapy aimed at reversing the autoimmune disease, ankylosing spondylitis. Approximately 200 patients will be chosen to participate in a clinical trial that aims to merge the latest molecular discoveries published b...

Researchers design unique method to induce immunity to certain STDs

Chlamydia trachomatis is the most common bacterial agent of sexually transmitted disease, accounting for more than a million reported infections in the United States each year. Researchers at the California NanoSystems Institute (CNSI) at UCLA and the David Geffen School of Medicine at UCL...

Lung cancer cells activate inflammation to induce metastasis

A research team from the University of California, San Diego School of Medicine has identified a protein produced by cancerous lung epithelial cells that enhances metastasis by stimulating the activity of inflammatory cells. Their findings, to be published in the January 1 issue of the journal Na...

Does HBV infection induce acute cellular DNA damage?

Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. There are two branches of the checkpoint response pathway, ataxia telangiectasia-mutated (ATM) pathway and ATM-Rad3-related (ATR) pathway. Virus replication presents the...

Maternal obesity can program fetal brain to induce adult-onset obesity

BUFFALO, N.Y. -- Researchers at the University at Buffalo have found that fetuses of obese mother rats were programmed in utero to develop obesity in adulthood. Moreover, they have shown for the first time that the metabolic programming occurs in the fetal hypothalamus, the area of the brain r...

Can rectal vitamin E induce remission in patients with mild to moderate ulcerative colitis?

It is believed that the generation of an exaggerated intestinal immune response to otherwise innocuous stimuli along with generation of oxygen free radicals plays a key role in the pathophysiology of UC. However, no disease-specific treatment for UC has yet emerged. Vitamin E is a major lipophilic...

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TARGETED GENE DELIVERY SIGNALS CANCER VACCINATION IN VIVO: Intravenous Infusions of Rexin-G Followed by Reximmune-C Induce Tumor Necrosis and Recruitment of Tumor Infiltrating Lymphocytes in Cancerous Lesions (ASCO 2008)

SAN MARINO, Calif., May 27 /PRNewswire/ -- Epeius Biotechnologies ( http://www.epeiusbiotech.com ) announced today that the results of a Phase I Feasibility Study of sequential targeted gene delivery -- using Rexin-G followed by Reximmune-C -- for cancer vaccination will be presented at the AS...

Telik Announces Publication of Positive Phase 1 Results of a Multicenter Study of Ezatiostat Hydrochloride (TELINTRA(R), TLK199) Tablets In Patients With Myelodysplastic Syndrome

...lular growth and differentiation of blood. TELINTRA has been shown to stimulate normal multilineage differentiation of blood stem cell precursors and induce cancer cell death in human leukemia cell lines. Additional information on TELINTRA is available at www.telik.com . About Telik Tel...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

...etter understanding of disease processes related to hypertension, heart disease, kidney failure and cancer. ZFNs are engineered proteins that induce double strand breaks at specific sites in an organism's DNA. Such double-strand breaks stimulate the cell's natural DNA-repair pathways and can resul...

Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study

...er reducing the bony support for the implant. The authors of the study suggest that the elasticity (low stiffness) of Trabecular Metal material may induce a transfer of stresses to the periacetabular bone that more closely replicates the normal physiologic load transfer, thereby decreasing the detrimenta...

Leading Experts Endorse Bioheart's Muscle Stem Cell MyoCell Therapy

...rt trials in Europe to date and added that "the myoblast therapy is at this time point the only stem cell therapy that is making the claim to actually induce neomyogenesis and that is why it deserves our attention." Dr. Warren Sherman, Director, Stem Cell Research and Regenerative Medicine, Columbia U...

MJFF's Rapid Response Innovation Awards Hit Mid-2009 With Over $1 Million Funded in High-Risk/High-Reward Approaches to Parkinson's Disease

...from the Spanish Influenza outbreak of 1918, documenting Parkinson's disease following exposure to flu virus. The researchers hypothesize that flu can induce aspects of PD including cell loss, as well as to show how viruses access the nervous system. Wassilios Meissner, MD, PhD, of University Hospit...

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induce in Medical Products

ndigo OPTIMA Laser System

Description:... The ndigo OPTIMA Laser System is designed to induce interstitial laser coagulation or tissue ablation using a near infrared laser source. When used to induce interstitial laser coagulation, the laser delivers a controlled level of la...
Company:Johnson and Johnson

Foundation® Modular Revision System

Description:...ular Revision System offers a femoral option and tibial insert which provides a specially designed cam action that engages at 60 degrees of flexion to induce a smooth stable femoral roll-back motion and allow for 130 degrees of flexion. The constrained tibial insert in conjunction with the femur is designed...
Company:Encore Medical Corporation

Foundation® Posterior Stabilized Knee

Description:...ndation® PS knee offers a femoral option and tibial insert which provides a specially designed cam action that engages at 60 degrees of flexion to induce a smooth stable femoral roll-back motion and allow for 130 degrees of flexion. Femoral component comes in a PS open box design with prominent lateral ...
Company:Encore Medical Corporation

Foundation Posterior Stabilized Knee

Description:...e Foundation PS knee offers a femoral option and tibial insert which provides a specially designed cam action that engages at 60 degrees of flexion to induce a smooth stable femoral roll-back motion and allow for 130 degrees of flexion. Femoral component comes in a PS open box design with prominent lateral ...
Company:Encore Medical Corporation

Foundation Posterior Stabilized Knee System

Description:...e Foundation PS knee offers a femoral option and tibial insert which provides a specially designed cam action that engages at 60 degrees of flexion to induce a smooth stable femoral roll-back motion and allow for 130 degrees of flexion....
Company:Encore Medical Corporation

OP-1

Description:... OP-1, also known as BMP-7, is a member of a class of naturally occurring growth factors called Bone Morphogenetic Proteins. OP-1 Implant is known to induce new bone formation in both developing and mature skeletal systems. The FDA approved OP-1 Implant under the Humanitarian Device Exemption (HDE) in Octo...
Company:Stryker Corporation
induce in Medical Definition

Artificial induction of immunity

...uses it to lose its ability to produce disease, but still leaves it able to induce immunity to tetanus when injected into subjects. The heated, denatured toxi...tibodies to fit specific antigens, then produce them in large quantities to induce temporary immunity in people in advance of exposure to a specific pathogen...

Hyperesthesia

...peresthesia", and increased sound sensitivity is called "auditory hyperesthesia". Causes Excessive consumption of caffeine can temporarily induce this condition in humans, [1] due to excessive stimulaton of the spinal cord, as well as the cortex and medulla in the central nervous system. Howe...

Muscle atrophy

...isease ; burns, liver failure, etc. Other syndromes or conditions which can induce skeletal muscle atrophy are congestive heart disease and liver disease. ... treatment Muscle atrophy can be opposed by the signaling pathways which induce muscle hypertrophy, or an increase in muscle size. Therefore one way in whi...
induce in Medical Dictionary

Yawning

...is the act of stretching and yawning . ... What makes us yawn and why does it seem to be contagious? ... The Physiological Theory -- Our bodies induce yawning to drawn in more oxygen or ... This theory might support observations that suggest fetal yawning . ... Provine goes on to say that ...

Temperature measurement

...splayed. ... ... sources of temperature measurement information. Most manufacturers ... Changes in temperature at the measurement junction induce a change in electromotive ... About temperature measurment and associated sensor issues ... Is temperature measurement difficult? ... Source...

Stimulants

...ants , also sometimes called psychostimulants, are psychoactive drugs which induce temporary improvements in either mental or physical function or both. Examp... of Abuse - Stimulants ... Overview: Stimulants are substances that induce a number of characteristic symptoms. ... effects of the more common stimul...

Skin Rashes

... reaction to a drug, infection or allergy. ... home > topics a-z list > skin rashes in children article " Healthcare ... All drugs may induce skin reactions, although ... A macularpapular rash is the most common type of drug-induced skin reaction. ... Discuss all types of rashes ,...

Skin Rash

...trations, causes, home care, pictures, and more. ... A simple rash is called dermatitis, meaning inflammation of the skin . ... All drugs may induce skin reactions, although ... A macularpapular rash is the most common type of drug-induced skin reaction. ... Discuss all types of rashes ,...

Rh factor

...h blood type incompatibility is still the leading cause ... Rh factor n. Any of several substances on the surface of red blood cells that induce a strong antigenic response in individuals lacking the substance The Rh factor is a type of protein on the surface of red blood cells. ......
induce in Biological News

Trio of signals converge to induce liver and pancreas cell development in the embryo

PHILADELPHIA - Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies. With regenerated cells, researchers hope to one day fill the acute shortage ...

Ben-Gurion University of the Negev researchers help find that hypnosis can induce synesthesia

NEW YORK, Oct. 23, 2008 -- Hypnosis can induce "synesthetic" experiences where one sense triggers the involuntary use of another within an average brain, according to a new study in the journal Psychological Science, the premiere publication of the Association for Psychological Society. Th...

Massey researchers induce cell death in leukemia

Researchers from the Virginia Commonwealth University Massey Cancer Center today presented preclinical research at the American Association of Cancer Research's annual meeting suggesting the potential of a new combination treatment for chronic lymphocytic leukemia (CLL). In this study, led by S...

Model identifies genes that induce normal skin cells to become abnormal

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the ...

Neuropathic pain: The sea provides a new hope of relief

... (nociceptive pathways) and cause the person to experience mildly uncomfortable stimuli as very painful (hyperalgesia), or stimuli that would normally induce no discomfort at all as painful (allodynia). Thus, cold drafts or lightly brushing the skin can produce intense pain, severely affecting the person's...

Stress signals link pre-existing sickness with susceptibility to bacterial infection

...dness, deafness, stroke-like episodes, epilepsy, ataxia, muscle weakness and kidney disease. The metabolic abnormalities that cause these effects also induce a stress signal intended to help the body overcome its energy deficit. The stress-signal induces the production of more mitochondria, the energy gene...

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induce in Biological Technology

Pepscan Achieves a Breakthrough With CLIPS Immunogen Technology: Synthetic Peptide Antigen is Able to Induce Fully Functional Antibodies Against a Formerly Intractable GPCR Target CXCR7

LELYSTAD, The Netherlands, April 6 /PRNewswire/ -- Today, Pepscan reports that it has achieved a major scientific breakthrough through the use of its CLIPS-based synthetic peptide immunogen technology. By constructing synthetic 3D mimics of the ligand binding-site on CXCR7 it has induced funct...

Therapure Biopharma Inc. announces collaboration with Induce Biologics Inc.

Ontario biotech companies work together on innovative bone protein technology TORONTO, Oct. 28 /PRNewswire/ - Thomas Wellner, President and CEO of Therapure BioPharma Inc. and Dr. Cameron Clokie, President and CEO of Induce Biologics Inc. today announced a development partnership utilizing an...

Symbiotic microbes induce profound genetic changes in their hosts

MADISON Though bacteria are everywhere from the air we breathe and the food we eat to our guts and skin the vast majority are innocuous or even beneficial, and only a handful pose any threat to us. What distinguishes a welcome microbial guest from an unwanted intruder? Research from the Uni...

PharmatrophiX, Initially Funded by the Alzheimer's Drug Discovery Foundation, Announces Exclusive Global Collaboration with Elan

...te a receptor on brain cells (p75), protecting the cell from damage caused by the toxic amyloid molecules associated with Alzheimer's disease, but not induce the side effects triggered by the much larger natural biologic molecules. Out of the more than one million small molecules he studied, he ultimately f...

Keryx Biopharmaceuticals, Inc. Announces Second Quarter 2009 Financial Results

... first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase (PI3K)/Akt pathway, a key signaling cascade that has been shown to induce cell growth and cell transformation. KRX-0401 has demonstrated both safety and clinical efficacy in numerous adult and pediatric tumor types, both as ...

Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Second Quarter 2009 Financial Results on Thursday, August 6, 2009 at 8:30am EDT

... first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase (PI3K)/Akt pathway, a key signaling cascade that has been shown to induce cell growth and cell transformation. KRX-0401 has demonstrated both safety and clinical efficacy in numerous adult and pediatric tumor types, both as ...
induce in Biological Products

Anisomycin from Sigma-Aldrich

Description:...olated fromStreptomyces griseolusthat inhibits protein synthesis. Acts by inhibiting peptidyl transferase activity in eukaryote ribosomes. Reported to induce apoptosis in a variety of cells including promyelocytic leukemia cells, Jurkat cells, ventricular myocytes, and colon adenocarcinoma cells. Initiates ...
Company:Sigma-Aldrich

ENGENISTM siRNA Test System from Yorkshire Bioscience Ltd

Description:...ving the probability of selected sequence to be a good target from 30% to 60%. It is therefore clear that the ability of computer-selected sequence to induce RNA interference has to be confirmed experimentally. The ENGENISTM siRNA Test System allows for screening a large number of potential siRNA target seq...
Company:Yorkshire Bioscience Ltd

MitoPT Detection of Mitochondrial Permeability from B-Bridge International

Description:... The MitoPT kit is used in conjunction with your existing apoptosis protocols. Grow your cells in culture and induce apoptosis according to your existing procedure (also reserve a non-induced population of cells as a negative control). Once you have induced apoptosis...
Company:B-Bridge International

TransIT-siQUEST Transfection Reagent from Mirus Bio Corporation

Description:... Cellular uptake of long double stranded RNA (dsRNA) has been shown to induce RNA interference in a diverse group of organisms as well as insect cells in... dsRNA-mediated destruction of the target messenger RNA (mRNA). Attempts to induce RNA interference using long dsRNA in mammalian cell lines have been met wit...
Company:Mirus Bio Corporation

TransIT-siQUEST Transfection Reagent from Mirus Bio Corporation

Description:... Cellular uptake of long double stranded RNA (dsRNA) has been shown to induce RNA interference in a diverse group of organisms as well as insect cells in... dsRNA-mediated destruction of the target messenger RNA (mRNA). Attempts to induce RNA interference using long dsRNA in mammalian cell lines have been met wit...
Company:Mirus Bio Corporation

SOS Soluble Protien Service from Genlantis

Description:... most insoluble clones The new protein Solubility Optimization Service (SOS) uses proprietary tools and know-how recently developed at Genlantis to induce solubility or significantly enhance solubility of recombinant proteins expressed in BL21(DE3) cells. The SOS process uses 24 unique conditions per gen...
Company:Genlantis
induce in Biological Definition

Apoptosis

...icity or exposure to ionizing radiation, such as ultraviolet or X-rays, can induce a cell to begin an apoptotic process. A fascinating example, resulting from...ogrammed cell death, excess of apoptotic material and altered clearance may induce autoreactive immune responses. On the other side of the spectrum, failure t...

Barr body

...ng that random inactivation only takes place when two X-chromosomes are present. The provision of an extra artificial Xic in early embryogenisis can induce inactivation of the single X found in male cells. The roles of Xist and Tsix appear to be antagonistic. The loss of Tsix expression on the fut...

Cancer

...ith mesothelioma . In more general terms, chemicals called carcinogens and free radicals are known to cause mutations. Chronic inflammation may induce malignancy, as neutrophil granulocytes secrete free radicals. Mutations can also be inherited. Inheriting certain mutations in the BRCA1 gene re...

Genetic code

...itiation codon (start codon). But unlike stop codons, these are not sufficient to begin the process; nearby initiation sequences are also required to induce transcription into mRNA and binding by ribosomes . The most notable start codon is AUG, which also codes for methionine. CUG and UUG, and in pro...

Cytotoxic T cell

...king it expand and eventually lyse . T C also release granzyme , a serine protease , that can enter target cells via the perforin-formed pore and induce apoptosis (cell death). Most T C cells have present on the cell surface the protein CD8 , which is attracted to portions of the Class I MHC molec...

DNA

...ain. Supercoiled DNA The B form of the DNA helix twists 360 per 10.6 bp in the absence of strain. But many molecular biological processes can induce strain. A DNA segment with excess or insufficient helical twisting is referred to, respectively, as positively or negatively " supercoiled ". DNA in ...
induce in Biological Dictionary

Triplet repeat expansion

...xpansion During in vitro DNA Replication ... DNA instability appeared to induce triplet repeat expansion in vitro. ... Abasic Sites induce Triplet - repeat Expansion during DNA Replication in Vitro ... The occu...

Termination codon

...ponsible for some ... Since premature termination codons are frequently known to ... regions where a premature termination codon should not induce nonsense-mediated mRNA decay. ... Effects of an Opal Termination Codon Preceding the nsP4 Gene Sequence in the ... when translation terminate...

RNA interference

...nce (RNAi) pathway. ... RNA interference (RNAi) is the process of mRNA degradation that is induced by ... Introduction of synthetic siRNAs can induce RNA interference in mammalian cells. ... An up-to-the-minute listing of publications using of RNA interference ... The following RNA Int...

Pseudorevertant

...f ... Symbiotic pseudorevertant of MYa179. This study. E. coli. MM294A. pro-82 thi-1 endA hsdR17 supE44 ... These pseudorevertant endonucleases induce E. coli SOS response (as evidenced by ... Both pseudorevertant proteins were purified and shown to increase specific ... Genetic characterizati...

Proto-oncogene

...ogenesis, and how the proto - oncogene is mutated to give rise to ... Britannica online encyclopedia article on proto - oncogene , ...ability to induce cancer. An oncogene is a sequence of deoxyribonucleic acid (DNA) that has been ... The oncogenes page provides a brief discussion of the ki...

Oncogene

...gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell. genetic material that carries the ability to induce cancer. An oncogene is a sequence of deoxyribonucleic acid (DNA) that has been altered or mutated from its original form, the proto- oncogene . ...
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(Date:9/30/2014)... Austin, TX (PRWEB) September 30, 2014 ... for Facial Plastic Surgery, has been approved to be ... of Facial Plastic and Reconstructive Surgery (AAFPRS) fellowship program. ... their meeting in Orlando, Florida. , The Educational and ... throughout the medical community. It represents the finest postgraduate ...
(Date:9/30/2014)... September 30, 2014 Gummy teeth ... gum depigmentation treatments for dark gums. Dark gums are ... people feel extremely self-conscious about their smiles. Dr. Farnoosh ... gums. “I am one of the few dental professionals ... have treated celebrities, business leaders, high-ranking officials and patients ...
(Date:9/30/2014)... HealthDay Reporter TUESDAY, Sept. ... supplements won,t prevent the return of a common type of ... In fact, 64.1 percent of those taking fish oil for ... over the course of 16 months, compared to 63.2 ... did not reduce the twin ills of inflammation or oxidative ...
(Date:9/30/2014)... MYERS, Fla. (PRWEB) September 30, 2014 ... Hospital, is giving breast cancer patients a new, more ... surgeries. , Women who undergo mastectomies, biopsies and lumpectomy ... and promote healing. But after seeing her patients describe ... felt compelled to create a new bra in her ...
(Date:9/30/2014)... New York, New York (PRWEB) September 30, 2014 ... will honor Kenro Izu – founder of the nonprofit, ... City on November 6, 2014, for building a hospital ... sustainable pediatric care. , Izu first encountered Cambodia’s ... suffering from a variety of disabilities and illnesses during ...
Breaking Medicine News(10 mins):Health News:Dr. Edward Buckingham Approved to be Fellowship Director for Facial Plastic Surgery 2Health News:Dr. Edward Buckingham Approved to be Fellowship Director for Facial Plastic Surgery 3Health News:Gummy Smile Dentist, Dr. Alex Farnoosh, is Now Offering Gum Depigmentation for Dark Gums 2Health News:Fish Oil Supplements Have Little Effect on Irregular Heartbeat: Study 2Health News:Fish Oil Supplements Have Little Effect on Irregular Heartbeat: Study 3Health News:Surgeon Creates New Bra for Breast Cancer Patients, Post-Surgery 2Health News:Surgeon Creates New Bra for Breast Cancer Patients, Post-Surgery 3Health News:Nobel Prize For Child Advocates Announces 2014 Health Award Honoree 2Health News:Nobel Prize For Child Advocates Announces 2014 Health Award Honoree 3
(Date:9/29/2014)... to a new Food and Brand Lab pilot study, ... participation in the National School Lunch Program (NSLP) by ... 16%! , Chefs Move to Schools (CMTS), an initiative ... schools in order to provide nutrition instruction to students ... , A CMTS event was held in an Upstate ...
(Date:9/29/2014)... team says recently identified radiation detection properties of a ... for homeland security and medical advances. , In a ... of Optics Letters , UT Arlington Physics Professor ... to fabricate transparent nanoscintillators by heating nanoparticles composed of ... formed. A scintillator refers to a material that ...
(Date:9/29/2014)... bad rap, and understandably so. The grain-of-rice-sized insects are ... of acres in the Western U.S. and Canada over ... belief, these pests may not be to blame for ... through the region. Instead, weather and topography play a ... these bark-boring beetles. , New research led by the ...
Breaking Biology News(10 mins):Chefs move to schools can increase school meal participation and vegetable intake among students 2UT Arlington researchers develop new transparent nanoscintillators for radiation detection 2UT Arlington researchers develop new transparent nanoscintillators for radiation detection 3Tree killers, yes, fire starters, no: Mountain pine beetles get a bad rap, study says 2Tree killers, yes, fire starters, no: Mountain pine beetles get a bad rap, study says 3Tree killers, yes, fire starters, no: Mountain pine beetles get a bad rap, study says 4
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