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Abatement Technologies Sees Strong Demand as Hospitals Prepare for Stage 6 Flu Pandemic

... use special HEPA filters to remove deadly, infectious airborne pathogens from the air. According to independent testing, these systems can capture or inactivate more than 99.99% of the 0.3-micron size (0.000012-inch) organisms that pass through them. Portable HEPA-CARE models roll quietly to wherever the...

Catalyst Biosciences Announces Agreement With MedImmune to Discover and Develop Engineered Protease Therapeutics

...ment to include a second target. Alterase therapeutics are next-generation, protease biologics engineered with the ability to catalytically cleave and inactivate disease-causing proteins. MedImmune will be responsible for all development, manufacturing, and commercialization efforts associated with the products...

SANYO Donates Systems Effective vs. Flu to United Nations Organization Affiliate - World Association of Former United Nations Internes and Fellows (WAFUNIF)

... and infecting healthy cells. Independent testing in Japan and other countries has also demonstrated that electrolyzed water has the unique ability to inactivate human viruses. For more information on the 'Virus Washer' technology visit http://us.sanyo.com/vw . About SANYO SANYO Electric Co...

LSUHSC research finds single gene controls growth of some cancers

...ancers related to the Epstein-Barr virus and that existing therapeutics can inactivate it, will be published in the June 12, 2009 online issue of PLoS Pathogens ...erapeutics such as Vitamin K that can change oxidative stress within cells, inactivate EBNA1," notes Dr. Aiyar, who is also a member of the faculty of the LSUHSC ...

Family Health International Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research Project Led by David Sokal, M.D.

... research project led by David C. Sokal, M.D., studying a novel approach to inactivate HIV with minimal interference during breastfeeding. Dr. Sokal's projec... its tip and saturating the material with a commonly used compound that can inactivate HIV without harming the child. The researchers for the project are also lo...

Haledyne Debuts Air Sanitizing Technology for Healthier Home

..., or be in contact with, the UV-C emitter bulb, which is always shielded by the medallion cover. If the medallion cover is removed, a microswitch will inactivate the circuit and the bulbs will not be lit. The Healthy Fan starts at $229.00 and can be purchased online at www.HealthyFan.com . On average, the...

Six-Minute Surgical Instrument Sterilizer to Protect Patients and Save Hospitals $Billions

... effective means for healthcare facilities to immediately lower operating costs and properly protect patients undergoing surgery." The ability to inactivate all pathogens, including spores, with room temperature techniques in just six minutes to achieve 100% kill was absolutely unimaginable only a couple o...

Disruptive Hand Sanitation Product to Save Healthcare Industry Billions

...allowing hospitals to immediately lower infection rates, reach zero tolerance targets, and properly protect patients and workers." The ability to inactivate deadly pathogens such as MRSA and C. difficile spores and fully sanitize a nurse's or doctor's bare or gloved hands, in just one second, was absolutel...

Scientists May Have New Way to Fight the Flu

...t a broad range of flu strains. "We identified new human antibodies that inactivate influenza, not just bird flu, but any of the seasonal influenza viruses tha...nstitute. The antibodies recognize a new part of the influenza virus and inactivate the virus by a new mechanism, Marasco said, "so it's really a new target, n...

Anti-HIV gel shows promise in large-scale study in women

... PRO 2000 inhibits the entry of HIV into cells; BufferGel boosts the natural acidity of the vagina in the presence of seminal fluid, which can help to inactivate HIV and other pathogens. The volunteers in HPTN 035 were divided at random into four equal-sized groups: Those using BufferGel prior to eng...
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FDA Advisory Panel Makes Favorable Recommendation for GlaxoSmithKline and Genmab's ARZERRA(TM) (ofatumumab)

...r surface. B-cells normally protect the body from invading pathogens by developing into plasma cells, which make antibodies. These antibodies directly inactivate pathogens or attach to pathogens to prepare them for destruction by other white blood cells. About Ofatumumab Ofatumumab is an investigationa...

CSL Behring Receives Orphan-Drug Exclusivity for RiaSTAP(TM), First and Only Approved Treatment of Acute Bleeding Episodes in Patients with Congenital Fibrinogen Deficiency

...plasma donors for prior exposure to certain viruses, by testing for the presence of certain current virus infections, and by a process demonstrated to inactivate and/or remove certain viruses during manufacturing. Despite these measures, such products may still potentially transmit disease. There is also the ...

Silence Therapeutics to Receive $1.9m Milestone Payment as Pfizer and Quark Commence Phase II Trial

...ize winning technology and one of the most exciting areas of drug discovery today. It represents a completely new approach to selectively 'silence' or inactivate disease relevant genes and as such it has the potential to create a new class of therapeutic products. RNAi could therefore offer a therapeutic approa...

Silence Therapeutics Announces Board Changes

...ize winning technology and one of the most exciting areas of drug discovery today. It represents a completely new approach to selectively 'silence' or inactivate disease relevant genes and as such it has the potential to create a new class of therapeutic products. RNAi could therefore offer a therapeutic approa...

Sangamo BioSciences Announces Presentation of Data on ZFP Therapeutic for Glioblastoma at American Association for Cancer Research (AACR) Meeting

...h as dexamethasone, must be administered to patients pre- and post-surgery to stop the brain-swelling caused by the tumor and surgery. Glucocorticoids inactivate or kill the T-cells through a protein known as the glucocorticoid receptor (GR), limiting the benefit of this novel therapy. Currently, this approach ...

PTC Therapeutics Announces Publication of Preclinical Data in PNAS

...ver 2,400 distinct genetic disorders where nonsense mutations are the cause of the disease in a significant percentage of patients. Nonsense mutations inactivate gene function and are known to cause anywhere from five to 70 percent of the individual cases of most inherited diseases, such as cystic fibrosis (10%...

Afid Therapeutics Obtains Positive Evaluation of its Triple Mode Viral Sequestration Agents

...ed results were obtained from a specialized, independent third party testing organization. The new viral sequestrating agents are designed to bind and inactivate viruses by 3 critical mechanisms thus blocking infection. They are aimed at viruses responsible for common causes of influenza in addition to SARS, bi...

Aeolus Pharmaceuticals' AEOL 10113 May Play an Important Role Regulating the Oxidative Damage Induced by Ionizing Radiation

...75% of pediatric patients with central nervous system malignancies. Success in controlling a brain cancer by radiation therapy hinges on being able to inactivate the cancer cells while preserving normal tissue function. This study evaluated retinal endothelial cell response to radiation in the presence of a m...

Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections

...ll in patients with cystic fibrosis as those patients have much higher levels of other negatively charged components in their sputum which bind to and inactivate the antimicrobial peptides. As a result, patients with cystic fibrosis are at high risk for lung infections throughout their lifetimes and the repeate...
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GenCatch™ Viral RNA Mini-Prep Kit

Description:...ethod to purify viral nucleic acids from cell-free samples. This system utilizes guanidine thiocyanate and 2-mercaptoethanol for their capabilities to inactivate RNase and denature proteins. Purified viral RNA is suitable fro applications such as RT-PCR, Northern and RNase protection assays. This system is idea...
Company:Epoch Biolabs, Inc

IGF-1 EIA Endocrine Function 026-AC-27F1 Insulin Growth Factor

Description:...a single IGF-1 determination is considered more reliable than a random GH determination. Patient samples are incubated briefly with a reagent to inactivate binding proteins, and then diluted for assay. In the OCTEIA IGF-1 kit a purified sheep polyclonal anti-IGF-1 is coated onto the inner surface of polys...
Company:ALPCO Diagnostics
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Protein C

...predisposes one to the formation of ... The function of protein C is to inactivate factor Va and factor VIIIa (the 'a' ... A lack (deficiency) of protein...Ia. ... Activated Protein C is a serine protease which functions to inactivate Factors Va and VIIIa. ... normal level of Protein C , but decreased func...
inactivate in Biological News

Use of high hydrostatic pressure to inactivate Hepatitis A virus in oysters studied

NOAA/Virginia Sea Grant has awarded Virginia Tech $119,000 to study whether high hydrostatic pressure will inactivate Hepatitis A virus in both shucked and unshucked oysters. The project, led by Daniel Holliman, an M.D. with the High Pressure Processing Laboratory, and Laura Douglas, lab manager,...

Female human embryos adjust the balance of X chromosomes before implantation

... stronger at the morula and blastocyst stages. "Our results are the first to show that, contrary to what was previously published, human embryos do inactivate a single X chromosome before implantation. We have shown that major characteristics that are present in mouse pre-implantation embryos are present als...

Sugarcoating fruit fly development

...ion of specialised tissues and organs in the wrong places. The scientists found that in the absence of Ogt, Polycomb proteins are no longer able to inactivate developmental genes. They showed that one specific Polycomb protein, called Polyhomeotic, is modified with the sugar tag by Ogt and might be the link ...

The story of X -- evolution of a sex chromosome

...ious genetic mutations are eliminated. The XX pair in females does recombine, but for the Y, the only way to get rid of a bad mutation in a gene is to inactivate or delete the entire gene. Over millions of years, inactive genes are lost, and the Y shrinks. "If you have no recombination, natural selection is ...

Jefferson researcher awarded Landenberger Foundation grant for ALS research

...creased during the disease, rendering pharmacological treatments for ALS mostly ineffective. This grant will support research towards finding ways to inactivate these transporter proteins to counteract their negative effect on ALS therapy. We are extremely grateful to the Margaret Q. Landenberger Research Fou...

SIRT1 takes down tumors

...And several studies suggest that it does. But other work indicates that the protein aids tumors. For example, SIRT1 chops off acetyl groups, which can inactivate the tumor suppressor p53. Yuan et al. determined SIRT1's effect on the transcription factor c-Myc, whose expression surges in many breast, colon, a...

Researchers isolate protein domain linked to tumor progression

... family of enzymes known as matrix metalloproteinases (MMPs). Now, researchers at Rensselaer Polytechnic Institute have shown that creating drugs that inactivate a different part of the MMP enzyme could have the capacity to target the tumor without the damaging side effects. Their findings, which hold promise f...

CSHL scientists discover how 'companion' cells to sperm protect them from genetic damage

... pass on to sperm. These small RNAs, the CSHL team shows, have the power to inactivate or "silence" specific DNA sequences. Thus they help set up gene expression ...ted from the companion cell and deposited into the sperm cells. There, they inactivate or "silence" transposon DNA via a phenomenon known as RNA interference. ...

Stowers Institute's Baumann Lab identifies key step in maturation pathway of telomerase

...ctional product in a single-step reaction." The work sheds light on human health by demonstrating that interfering with telomerase maturation can inactivate telomerase. Because finding inhibitors for telomerase has been challenging, the identification of a whole set of potential new targets is welcome news...

Cell movements totally modular, Stanford study shows

...boring cells, directional sensing and cell division. Vitorino went on to inactivate the more than 100 genes suspected of playing a role in controlling movement...dicating a modular system at work. "The cells don't need to activate and inactivate thousands of proteins to control sheet movements," Vitorino said. "Instead ...
inactivate in Biological Technology

SANYO Donates Air Purification Systems Effective Against Flu Viruses to New York Airports and Schools

...he technology and its use of electrolyzed water to inactivate human viruses. This is not only a way for us to en... that electrolyzed water has the unique ability to inactivate human viruses. "Electrolyzed water technology...es an 'Electrolyzed Water Disinfecting Element' to inactivate viruses and other airborne microbes and particles....

Bert W. O'Malley, M.D., Recipient of the 2008 National Medal for Science, Joins Bionovo's Scientific Advisory Board

...ntributed the first substantiated understanding of the mechanism of action of how agonists and antagonists of female hormones structurally activate or inactivate a receptor's ligand binding domain for eventual transcriptional regulation. His work was furthered when he discovered that intracellular coactivator/c...

Hong Kong Biotech Company, Filligent, Announces CE Certification of Its Revolutionary, Anti-Infective Medical Face Mask, the BioMask

...ssion of diseases. Using biochemistry at the molecular level, its proprietary technologies seek out dangerous pathogens and chemicals and then kill or inactivate them before they enter the human body. Filligent is able to select and filter out dangerous agents from the air, water, and from off surfaces -- inclu...

Secretropin(R) - Effective, Preferable, Affordable as an Alternative to Injectable Growth Hormone - Gains Momentum

...test nanoliposomal technology, which wraps the active agents in a protective envelop. Until this delivery technology was available, stomach acid would inactivate and destroy the active agents responsible for the increase in growth hormone production. Prior to Secretropin(R), this left injectable growth ho...

Sinovac Enters Veterinary Vaccine Market with Inactivated Rabies Vaccine

...rvicing the Chinese market. Our rabies vaccine is one of the first inactivated versions to be developed domestically in China. It is expected that the inactivate rabies vaccine will be manufactured in China, which should afford us a competitive cost advantage over imported formulations." Mr. Yin continue...

ImQuest Receives $6.4 M Five Year Award from NIH to Develop Long-Lasting Combination Topical Microbicides To Prevent HIV Transmission

...olio of microbicide products and the proposed combination microbicide will provide a three layer barrier to HIV infection. Initially, the product will inactivate HIV and HIV-infected cells in the semen upon introduction to the vagina. Secondly, two separate products in the combination will prevent the initial a...

Silence Therapeutics Receives Allowance from United States Patent and Trademark Office for its Core RNAi Patent

...ize winning technology and one of the most exciting areas of drug discovery today. It represents a completely new approach to selectively 'silence' or inactivate disease relevant genes and as such it has the potential to create a new class of therapeutic products. RNAi could therefore offer a therapeutic approa...

Silence Therapeutics Patent Update

...ize winning technology and one of the most exciting areas of drug discovery today. It represents a completely new approach to selectively 'silence' or inactivate disease relevant genes and as such it has the potential to create a new class of therapeutic products. RNAi could therefore offer a therapeutic approa...

Silence Obtains Important Patent Protection for Lead Internal Development Compound, Atu027

...ize winning technology and one of the most exciting areas of drug discovery today. It represents a completely new approach to selectively 'silence' or inactivate disease relevant genes and as such it has the potential to create a new class of therapeutic products. RNAi could therefore offer a therapeutic approa...

Organizational Changes at Silence Therapeutics

...ize winning technology and one of the most exciting areas of drug discovery today. It represents a completely new approach to selectively 'silence' or inactivate disease relevant genes and as such it has the potential to create a new class of therapeutic products. RNAi could therefore offer a therapeutic approa...
inactivate in Biological Products

Tritirachium album Proteinase K from USB Corp.

Description:... Concentration: 20 - 50 units/mg Applications: Used in the isolation of native, high molecular weight DNA and RNA. *Used as a general protease to inactivate DNases, RNases and to degrade proteins. *Specifically modifies cell surface proteins and glycoproteins for analysis of membrane structures for prote...
Company:USB Corp.

RNase Inhibitor (Cloned) from Ambion

Description:...eatic RNase A type enzymes. The mode of inhibition is noncompetitive; the inhibitor tightly binds RNases in a 1:1 ratio. The enzyme has been shown to inactivate RNases present in many tissues and cell types. Addition of the ribonuclease inhibitor has been shown to be useful whenever the integrity of RNA must b...
Company:Ambion

Sterilizing UV PCR Workstation from UVP

Description:...R Workstation brings together UV irradiation and antimicrobial stainless steel to create a dual-attack environment against PCR contamination! Quickly inactivate DNA between experiments with UV Maintain a clean environment with antimicrobial coated stainless steel Decontaminate apparatus and reagents within...
Company:UVP
inactivate in Biological Definition

Barr body

...methylation and histone H2A ubiquitylation , as well as direct modification of the DNA itself, via the methylation of CpG sites . These changes help inactivate gene expression on the inactive X-chromosome and to bring about its compaction to form the Barr body. See also X-inactivation Sex-deter...

Enzyme

...rating these regions by long stretches of 'spacer' amino acids where mutation is much less critical (although some mutations in these regions can also inactivate the product). This has the additional effect of making each region act, relative to mutation, somewhat like an independent subunit which can be duplic...
inactivate in Biological Dictionary

UvrA

...ative aminopeptidase gene (pepP) ... Here we suggest that uvrA and the nucleotide excision repair pathway are ... groups, it was necessary to inactivate the uvrA dependent nucleotide excision repair gene. ... mutant strain deficient in alkA tagA and uvrA , then exposed ... Crystal Structure o...

Transposable element

...classification ... Did You Know? Transposase is an enzyme that catalyzes transposition. ... Why the insertion of a transposable element can inactivate a gene? ... Transposable Genetic Elements . A. There are three types of transposable ... Transposable elements in eukaryotes are of two ...

Gene silencing

...liers with expert market research, ... 2008 Gene Silencing Dashboard™ dives ... GRAHAM : Gene silencing is a technology that permits one to inactivate genes in ... He's the principal inventor of Benitec's gene silencing technology. ... Article : RNAi Gene Silencing Applications Advance Gen...
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