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impairing in Medical News

Drug Combo Blocks Pain Without Impairing Movement

Chili pepper compound plus lidocaine derivative anesthetizes without numbness in rat study,, WEDNESDAY, Oct. 3 (HealthDay News) -- A visit to the dentist could one day involve no pain and no numbness, Harvard researchers report. In experiments with rats, the scientists combined ca...

Industrial Chemicals Are Impairing the Brain Development of Children Worldwide

Fetal and early childhood exposures to industrial chemicals in the environment can damage the developing brain and can lead to neurodevelopmental disorders (NDDs)—autism,// attention deficit disorder (ADHD), and mental retardation. Still, there has been insufficient research done to identify the in...

Dementia induced and blocked in Parkinson's fly model

... St. Louis, July 31, 2009 Parkinson's disease is well-known for impairing movement and causing tremors, but many patients also develop other serious problems, including sleep disturbances and significant losses in cognitive ...

Cell transplantation and cardiac repair

...onding author Dr. Hans Dohman of the Hospital Pro-Cardiaco in Rio de Janeiro, Brazil. While previous reports observed that microvascular obstruction impairing cell uptake by the heart could be an issue, the team hypothesized that an intravenous approach may overcome that potential. "We hypothesized that a...

EyeCare America Reminds Seniors: "Don't Lose Sight of Your Independence"

... of the things many seniors have trouble doing due to various eye diseases. In fact, by the age of 65, one in three Americans has some form of vision impairing eye disease. However, with the U.S. economy experiencing a major downturn, senior communities on fixed incomes are struggling to pay for health care....

Ironwood and Forest to Present Additional Phase 2b Data for Novel Gastrointestinal Agent Linaclotide

...ation of incomplete evacuation, and fewer than three bowel movements per week. The discomfort of CC significantly affects patients' quality of life by impairing their ability to work and participate in typical daily activities. About Digestive Disease Week (DDW) DDW is the largest international g...

25 Clinical Abstracts at National Conference Spotlight Clinical Utility of Somanetics INVOS System in Neonates

...atent - after birth instead of closing naturally as expected. In these cases, the PDA causes abnormal blood circulation, often straining the heart and impairing blood flow throughout the body. Studies are exploring how cerebral/somatic oximetry via the INVOS System may potentially be used to help detect oxygen...

VIA Pharmaceuticals Announces Positive Phase 2 Results of VIA-2291 in Cardiovascular Patients Using Serial MDCT Imaging of Coronary Plaque

...ture clinical trial; -- our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA...

Drug shows activity in men with advanced prostate cancer

...her evaluate the drug RD162 and a closely related compound, MDV3100. According to their findings, both drugs inhibit the androgen receptor function by impairing the receptor's ability to enter a CRPC cell's nucleus (called nuclear translocation), blocking it from binding to the DNA of its target genes, and pre...

Contact Lenses Boost Kids' Self-Image

...recreational activities without vision correction rather than risk breaking their glasses. Unlike glasses, contact lenses provide clear vision without impairing peripheral vision, so children may feel that their athletic competence improves, because they can see more clearly while participating in recreational...
impairing in Medical Technology

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

... leading to increased bioavailability of the opioid. Although the combination of EtOH and prescription opioids is frequently cited as having increased impairing effects, very few studies have examined the extent of the pharmacokinetic (PK) and pharmacodynamic (PD) interaction between them, particularly when ta...

New Bisphenol A Study Is of Very Limited Relevance to Human Health

...f Environmental Health Sciences (NIEHS). The study, "Neonatal bisphenol A exposure alters rat reproductive development and ovarian morphology without impairing activation of gonadotropin releasing hormone neurons," was funded by NIEHS and published online June 17 by the journal Biology of Reproduction. The st...

VIA Pharmaceuticals Meets With FDA to Discuss Next Steps For VIA-2291 and Phase 3 Outcome Trial in Cardiovascular Disease

...any future clinical trial; -- our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA- 2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA-2291 ...

IBM and EU Partners Create a Better Way to Fight AIDS Virus

...ariant. EuResist is a powerful online system that helps doctors choose the treatment with the highest probability of halting virus replication and impairing evolution of drug resistance. Although there have been tremendous leaps and bounds in the management of the virus that causes AIDS, HIV has the ...

Ironwood and Forest Present Additional Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation

...mplete evacuation, and fewer than three bowel movements per week. The discomfort and bloating of CC significantly affects patients' quality of life by impairing their ability to work and participate in typical daily activities. About Digestive Disease Week (DDW) DDW is the largest international gath...

Stallergenes S.A.: Positive Results From a Phase IIb/III Clinical Trial on the House Dust Mite Desensitization Tablet

...use dust mites can trigger allergic rhinitis, worsening over time with a natural progression towards asthma. The symptoms may be severe, significantly impairing patients' quality of life. About the Stalair(R) Development Program According to World Health Organization (WHO) estimates, 20 to 25% of...

Raptor Pharmaceuticals Corp. Announces Positive Phase IIa Clinical Study Results for Convivia(TM) Program

...DH2 deficiency, sometimes referred to as "Asian flushing syndrome," is an inherited metabolic disorder affecting 40% to 50% of East Asian populations, impairing the activity of the liver enzyme aldehyde dehydrogenase ("ALDH2"). When people with ALDH2 deficiency drink alcoholic beverages, there is an accumulati...

VIA Pharmaceuticals Announces Positive Results of Phase 2 Studies of VIA-2291 in Patients With Serious Cardiovascular Disease

...ts for the FDG-PET clinical trial; -- failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA-2291 on e...

VIA Pharmaceuticals Completes Patient Visits in Phase 2 Acute Coronary Syndrome (ACS) Trial

...ts for the FDG-PET clinical trial; -- failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA-2291 on e...

VIA Pharmaceuticals to Present at American Heart Association Scientific Sessions 2008

...for the FDG-PET clinical trial; -- failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA-2291 o...
impairing in Medical Products

Cardiff Pediatric Contrast Test

Description:... the ability of the visual system to detect large but faint targets. There are some pathological conditions that reduce contrast sensitivity without impairing visual acuity, and the test will help in the identification of these conditions. However, reduced contrast sensitivity and reduced visual acuity o...
Company:Richmond Products, Inc.

Symbia T6, TruePoint SPECT·CT system

Features:... incredibly fast CT acquisition with the best possible dose utilization CT CARE Solutions designed to keep radiation exposure to a minimum without impairing scanner performance or image quality. e.media patient comfort and education system for interactive multimedia capability. syngo , Siemens' un...
Company:Siemens Medical Solutions USA, Inc.
impairing in Biological News

A silent pandemic: Industrial chemicals are impairing the brain development of children worldwide

Fetal and early childhood exposures to industrial chemicals in the environment can damage the developing brain and can lead to neurodevelopmental disorders (NDDs)--autism, attention deficit disorder (ADHD), and mental retardation. Still, there has been insufficient research done to identify the ind...

Mice brains shrink during winter, impairing some learning and memory

The brains of one species of mouse actually shrink during the winter, causing the mice to have more difficulty with some types of learning, a new study found. The results showed that, during the short days of winter, white-footed mice had impaired spatial memory ?the mental map that helps them r...

Codeine use and accident risk

...d more than approximately 400 tablets per year, the risk of being involved in a traffic accident was 3 times as large. When the use of other potential impairing medicines was excluded, the risk of accident sank significantly. For sporadic codeine users there was no increased risk of accident. There was not a s...

Understanding how oxidative stress impairs endothelial progenitor cell function

...idative damage is a possibility because once the damage has occurred it may not be reversible." High cholesterol causes increased oxidative stress, impairing the function of EPCs. In addition to being implicated in cardiovascular diseases, oxidative stress is also a factor in diabetes. "Further studies o...

Systems biology brings hope of speeding up drug development

...drome is the term for various conditions that can lead to diseases such as type 2 diabetes where cells of the body develop resistance against insulin, impairing the regulation of blood glucose levels. The aim of SBMS is to understand the molecular and cellular systems that underlie risk factors associated with...

Researchers analyze how new anti-MRSA abtibiotics function

...e the health and integrity of the cell wall are critical to the survival of these organisms, it is not surprising that many antibiotics work by either impairing biosynthesis of the cell wall, or simply bind to it to inhibit full structural maturation. In 2006, Mobashery and his team of researchers provided the...

Turtle studies suggest health risks from environmental contaminants

... The same chemicals that keep food from sticking to our frying pans and stains from setting in our carpets are damaging the livers and impairing the immune systems of loggerhead turtlesan environmental health impact that also may signal a danger for humans. Jennifer Keller, a researcher at ...

Scientists identify molecular cause for one form of deafness

...Researchers have now learned that mutations in a protein called espin can cause floppiness in tiny bundles of protein filaments within the hair cells, impairing the passage of vibrations and resulting in deafness. Filamentous actin (F-actin) is a rod-like protein that provides structural framework in livin...

Scientists unravel clue in cortisol production

...al. But the hormone's effects are many and varied, lowering the activity of the immune system, helping create memories with short-term exposure, while impairing learning if there's too much for too long. Given the variety of its effects,understanding how cortisol is made is essential to producing medications t...

Heavy smoking cuts women's chance of pregnancy -- even with donated oocytes

...if it is confirmed as a real association it suggests that, paradoxically, tobacco constituents affect the uterus in different ways in different women, impairing implantation in some and having the opposite effect in others. "It is already known that there is paradoxical dose-dependent effect of nicotine ...
impairing in Biological Technology

VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ

...ients in any future clinical trials; our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; our ability to successfully complete our clinical trials of VIA-2291 on expecte...

New Test from Quest Diagnostics Helps Physicians Choose HIV Antiretroviral Therapy in Patients with History of Drug Resistance

...y. About HIV and AIDS HIV, or the human immunodeficiency virus, is a retrovirus that infects cells of the human immune system, destroying or impairing their function. The two major viruses that cause AIDS are HIV-1 and HIV-2. The most common, HIV-1, is found worldwide, while HIV-2 is primarily confin...

VIA Pharmaceuticals' DGAT1 Inhibitors Featured in American Diabetes Association Poster Presentation

...ture clinical trial; -- our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of ...

VIA Pharmaceuticals Announces Complete Enrollment in FDG-PET Phase 2 Study of VIA-2291 in Cardiovascular Patients

...ture clinical trial; -- our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of ...

VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ

...ture clinical trial; -- our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA...

VIA Pharmaceuticals to Present Poster at AHA Arteriosclerosis, Thrombosis and Vascular Biology Conference 2009

...y future clinical trial; -- our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA-229...

VIA Pharmaceuticals Complies With NASDAQ Rules

...well as any future clinical trial; our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; our ability to successfully complete our clinical trials of VIA-2291 on expec...

VIA Pharmaceuticals Secures Financing Up to $10.0 Million

...well as any future clinical trial; our failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; our ability to successfully complete our clinical trials of VIA-2291 on expec...

Intra-Cellular Therapies Reports Positive Final Results of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

...rch, Chief of Sleep Medicine for the Henry Ford Hospital Sleep Disorders and Research Center. "These data show that ITI-007 can maintain sleep without impairing next day functioning." SUMMARY OF PHASE II SMI RESULTS ITI-007 is an orally available investigational new drug being developed at low dose...

VIA Pharmaceuticals Announces Grant of New Patent on Lead Compound VIA-2291

...y future clinical trial; -- failure to obtain sufficient data from enrolled patients that can be used to evaluate VIA-2291, thereby impairing the validity or statistical significance of our clinical trials; -- our ability to successfully complete our clinical trials of VIA...
impairing in Biological Definition

Long-term potentiation

...he accuracy of these maps determines how well a rat learns about its environment, and thus how well it can navigate about it. Tonegawa found that by impairing the NMDA receptor, specifically by genetically removing the NMDAR1 subunit in the CA1 region, the place fields generated were substantially less spe...
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